Diagnostic value of microRNAs for malignant pleural mesothelioma: A mini-review

Malignant pleural mesothelioma (MPM) is a type of cancer originating from the pleura with high aggressiveness and poor prognosis. A timely diagnosis is crucial to improve its prognosis. Laboratory biomarkers have significant advantages of reduced invasiveness, low cost, and are observer-independent, and therefore represent a promising diagnostic tool for MPM. MicroRNA is a family of non-coding RNA that regulates gene expression at the post-transcriptional level. Accumulated studies showed that microRNA, either in tissue, circulating, and body fluid, has potential diagnostic value for various disorders. Here, we reviewed the diagnostic value of microRNA for MPM.

Automated summary

Malignant pleural mesothelioma is a highly aggressive cancer with a poor prognosis, emphasizing the importance of timely diagnosis. Laboratory biomarkers offer advantages of reduced invasiveness and cost, making them a promising diagnostic tool. MicroRNA has potential diagnostic value in tissue, circulating, and body fluids.