Fluorescent sensor for in-vivo bio-imaging, precise tracking of Fe3+ ions in Zebrafish embryos and visual measuring of Cu2+ ions in pico-molar level

Feasibly synthesized novel rhodam ne based chemosensor (RS) has been described for the detection of paramagnetic and biologically important Cu2+ and Fe3+ ions. Among all the transition metal ions, this chemosensor was able to precisely spot out the Cu2+ /Fe3+ ion couple by its spirolactam cleavage, consequently enhanceing their absorbances at 521 and 529 nm for Cu2+ and Fe3+ ions respectively even at low concentrations [263 pM (Cu2+) and 2 nM (Fe3+)], which is prominently lower than the WHO and the United States Environmental Protection Agency (USEPA) strategies. This metal pair (Cu2+/Fe3+) has more tendencies to cleave the lactam ring even in the presence of higher concentrations of other relevant metal ions. Such remarkable behaviour of RS has been motivated us to apply zebrafish bio-imaging and molecular logic circuits. (C) 2020 Published by Elsevier B.V. on behalf of King Saud University.

Automated summary

The newly synthesized chemical sensor RS can accurately detect Cu2+ and Fe3+ ions, effectively enhancing their absorption peaks even at low concentrations, and demonstrating high detection sensitivity. Its remarkable properties and performance in the presence of different metal ions make it suitable for zebrafish bio-imaging and molecular logic circuits.