4.5 Article

Thiophene-Pyrazolourea Derivatives as Potent, Orally Bioavailable, and Isoform-Selective JNK3 Inhibitors

Related references

Note: Only part of the references are listed.
Article Biochemistry & Molecular Biology

Discovery of 3-alkyl-5-aryl-1-pyrimidyl-1H-pyrazole derivatives as a novel selective inhibitor scaffold of JNK3

Youri Oh et al.

JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2020)

Article Chemistry, Medicinal

Novel scaffold evolution through combinatorial 3D-QSAR model studies of two types of JNK3 inhibitors

Hoyong Jung et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)

Article Neurosciences

Increased levels of cerebrospinal fluid JNK3 associated with amyloid pathology: links to cognitive decline

Sarah Gourmaud et al.

JOURNAL OF PSYCHIATRY & NEUROSCIENCE (2015)

Article Chemistry, Medicinal

Pyridopyrimidinone Derivatives as Potent and Selective c-Jun N-Terminal Kinase (JNK) Inhibitors

Ke Zheng et al.

ACS MEDICINAL CHEMISTRY LETTERS (2015)

Article Multidisciplinary Sciences

Structural Basis and Biological Consequences for JNK2/3 Isoform Selective Aminopyrazoles

HaJeung Park et al.

SCIENTIFIC REPORTS (2015)

Article Biochemistry & Molecular Biology

Discovery of Potent and Selective Covalent Inhibitors of JNK

Tinghu Zhang et al.

CHEMISTRY & BIOLOGY (2012)

Article Neurosciences

JNK3 Perpetuates Metabolic Stress Induced by Aβ Peptides

Sung Ok Yoon et al.

NEURON (2012)

Article Biochemistry & Molecular Biology

JNK Inhibition Protects Dopamine Neurons and Provides Behavioral Improvement in a Rat 6-Hydroxydopamine Model of Parkinson's Disease

Candice E. Crocker et al.

ACS CHEMICAL NEUROSCIENCE (2011)

Article Biochemistry & Molecular Biology

Differences in activation of ERK1/2 and p38 kinase in Jnk3 null mice following KA treatment

Luisa de Lemos et al.

JOURNAL OF NEUROCHEMISTRY (2010)

Article Chemistry, Medicinal

The neuroprotective action of JNK3 inhibitors based on the 6,7-dihydro-5H-pyrrolo[1,2-a]imidazole scaffold

PP Graczyk et al.

BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)

Article Multidisciplinary Sciences

JNK-mediated induction of cyclooxygenase 2 is required for neurodegeneration in a mouse model of Parkinson's disease

S Hunot et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Multidisciplinary Sciences

A critical role of neural-specific JNK3 for ischemic apoptosis

CY Kuan et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Review Biotechnology & Applied Microbiology

Targeting JNK for therapeutic benefit: From JuNK to gold?

AM Manning et al.

NATURE REVIEWS DRUG DISCOVERY (2003)

Article Biochemistry & Molecular Biology

Nocodazole-induced p53-dependent c-Jun N-terminal kinase activation reduces apoptosis in human colon carcinoma HCT116 cells

H Zhang et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2002)