4.5 Article

Validation of the new DSM-5-TR criteria for prolonged grief disorder and the PG-13-Revised (PG-13-R) scale

Journal

WORLD PSYCHIATRY
Volume 20, Issue 1, Pages 96-106

Publisher

WILEY
DOI: 10.1002/wps.20823

Keywords

Prolonged grief disorder; DSM‐ 5‐ TR; PG‐ 13‐ R; ICD‐ 11; pathological grief; bereavement; post‐ traumatic stress disorder

Categories

Funding

  1. Medical Research Council [MR/V001841/1] Funding Source: Medline
  2. NCATS NIH HHS [UL1 TR002384] Funding Source: Medline
  3. NCI NIH HHS [R35 CA197730, R21 CA218313, R01 CA106370] Funding Source: Medline
  4. NIA NIH HHS [T32 AG049666] Funding Source: Medline
  5. NIMHD NIH HHS [R01 MD007652] Funding Source: Medline
  6. NIMH NIH HHS [R21 MH095378, R01 MH063892, R21 MH121886] Funding Source: Medline
  7. NINR NIH HHS [R21 NR018693] Funding Source: Medline
  8. Wellcome Trust [200796/Z/16/Z] Funding Source: Medline
  9. Wellcome Trust [200796/Z/16/Z] Funding Source: Wellcome Trust

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Based on data from Yale University, Utrecht University, and Oxford University, the American Psychiatric Association has recently included Prolonged Grief Disorder (PGD) as a new mental disorder in the DSM-5-TR. The study found that PG-13-R grief symptoms represent a unidimensional construct with high internal consistency, and the PGD diagnosis was distinct from other mental disorders like PTSD, MDD, and GAD at baseline.
Although the concept of pathological grief dates back at least as far as Freud's Mourning and Melancholia, there has been opposition to its recognition as a distinct mental disorder. Resistance has been overcome by evidence demonstrating that distinctive symptoms of prolonged grief disorder (PGD) - an attachment disturbance featuring yearning for the deceased, loss of meaning and identity disruption - can endure, prove distressing and disabling, and require targeted treatment. In acknowledgement of this evidence, the American Psychiatric Association Assembly has recently voted to include PGD as a new mental disorder in the DSM-5-TR. We tested the validity of the new DSM criteria for PGD and of an adapted version of our PG-13 scale, the PG-13-Revised (PG-13-R), designed to map onto these criteria, using data from investigations conducted at Yale University (N=270), Utrecht University (N=163) and Oxford University (N=239). Baseline assessments were performed at 12-24 months post-loss; follow-up assessments took place 5.3-12.0 months later. Results indicated that the PG-13-R grief symptoms represent a unidimensional construct, with high degrees of internal consistency (Cronbach's alpha = 0.83, 0.90 and 0.93, for Yale, Utrecht and Oxford, respectively). The DSM PGD diagnosis was distinct from post-traumatic stress disorder (phi=0.12), major depressive disorder (phi=0.25) and generalized anxiety disorder (phi=0.26) at baseline. Temporal stability was remarkable for this diagnosis (r=0.86, p<0.001). Kappa agreement between a PG-13-R threshold symptom summary score of 30 and the DSM symptom criterion for PGD was 0.70-0.89 across the datasets. Both the DSM PGD diagnosis and the PG-13-R symptom summary score at baseline were significantly associated (p<0.05) with symptoms and diagnoses of major depressive disorder, post-traumatic stress disorder and/or generalized anxiety disorder, suicidal ideation, worse quality of life and functional impairments at baseline and at follow-up, in the Yale, Utrecht and Oxford datasets. Overall, the DSM-5-TR criteria for PGD and the PG-13-R both proved reliable and valid measures for the classification of bereaved individuals with maladaptive grief responses.

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