4.7 Editorial Material

Carbapenem and Colistin Resistance in Enterobacter: Determinants and Clones

Journal

TRENDS IN MICROBIOLOGY
Volume 29, Issue 6, Pages 473-476

Publisher

CELL PRESS
DOI: 10.1016/j.tim.2020.12.009

Keywords

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Funding

  1. National Natural Science Foundation of China [81772233, 81661130159, 81861138055]
  2. West China Hospital of Sichuan University (1.3.5 project for disciplines of excellence) [ZYYC08006, 312190022]
  3. Newton Advanced Fellowship, Royal Society, UK [NA150363]
  4. Medical Research Council [MR/S013660/1]
  5. MRC [MR/S013660/1] Funding Source: UKRI

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Enterobacter is a globally important pathogen with resistance to carbapenem and colistin. Further research is needed to understand colistin heteroresistance and the emergence of certain Enterobacter lineages clinically.
Enterobacter is a globally important pathogen. Here we clarify its taxonomy and review recent developments in its resistance to carbapenem and colistin, illustrating that Enterobacter has a large arsenal of mechanisms to grow under antimicrobial pressure. Further studies are required to decipher colistin heteroresistance and understand why certain Enterobacter lineages have emerged clinically.

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