Related references
Note: Only part of the references are listed.The mutational constraint spectrum quantified from variation in 141,456 humans
Konrad J. Karczewski et al.
NATURE (2020)
Escape from nonsense-mediated decay associates with anti-tumor immunogenicity
Kevin Litchfield et al.
NATURE COMMUNICATIONS (2020)
A guide to cancer immunotherapy: from T cell basic science to clinical practice
Alex D. Waldman et al.
NATURE REVIEWS IMMUNOLOGY (2020)
Single-Molecule Imaging Uncovers Rules Governing Nonsense-Mediated mRNA Decay
Tim A. Hoek et al.
MOLECULAR CELL (2019)
Quality and quantity control of gene expression by nonsense-mediated mRNA decay
Tatsuaki Kurosaki et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Advances in cancer immunotherapy 2019-latest trends
Stephan Kruger et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2019)
A dominant-negative effect drives selection of TP53 missense mutations in myeloid malignancies
Steffen Boettcher et al.
SCIENCE (2019)
The impact of nonsense-mediated mRNA decay on genetic disease, gene editing and cancer immunotherapy
Rik G. H. Lindeboom et al.
NATURE GENETICS (2019)
Biological plasticity rescues target activity in CRISPR knock outs
Arne H. Smits et al.
NATURE METHODS (2019)
CRISPR-Cas9-based mutagenesis frequently provokes on-target mRNA misregulation
Rubina Tuladhar et al.
NATURE COMMUNICATIONS (2019)
Evolution of the nonsense-mediated decay pathway is associated with decreased cytolytic immune infiltration
Boyang Zhao et al.
PLOS COMPUTATIONAL BIOLOGY (2019)
Identifying Genes Whose Mutant Transcripts Cause Dominant Disease Traits by Potential Gain-of-Function Alleles
Zeynep Coban-Akdemir et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2018)
Targeting nonsense-mediated mRNA decay in colorectal cancers with microsatellite instability
Adem Bokhari et al.
ONCOGENESIS (2018)
Negative selection in tumor genome evolution acts on essential cellular functions and the immunopeptidome
Luis Zapata et al.
GENOME BIOLOGY (2018)
Transcriptome-wide identification of NMD-targeted human mRNAs reveals extensive redundancy between SMG6-and SMG7-mediated degradation pathways
Martino Colombo et al.
RNA (2017)
Insertion-and-deletion-derived tumour-specific neoantigens and the immunogenic phenotype: a pan-cancer analysis
Samra Turajlic et al.
LANCET ONCOLOGY (2017)
Bayesian inference of negative and positive selection in human cancers
Donate Weghorn et al.
NATURE GENETICS (2017)
Simultaneous epitope and transcriptome measurement in single cells
Marlon Stoeckius et al.
NATURE METHODS (2017)
Using ALoFT to determine the impact of putative loss-of-function variants in protein-coding genes
Suganthi Balasubramanian et al.
NATURE COMMUNICATIONS (2017)
A pan-cancer genome-wide analysis reveals tumour dependencies by induction of nonsense-mediated decay
Zhiyuan Hu et al.
NATURE COMMUNICATIONS (2017)
Control of gene expression through the nonsense-mediated RNA decay pathway
Andrew Nickless et al.
CELL AND BIOSCIENCE (2017)
b Allelic imbalance of somatic mutations in cancer genomes and transcriptomes
Je-Keun Rhee et al.
SCIENTIFIC REPORTS (2017)
Universal Patterns of Selection in Cancer and Somatic Tissues
Inigo Martincorena et al.
CELL (2017)
Leveraging Rules of Nonsense-Mediated mRNA Decay for Genome Engineering and Personalized Medicine
Maximilian W. Popp et al.
CELL (2016)
Analysis of protein-coding genetic variation in 60,706 humans
Monkol Lek et al.
NATURE (2016)
The rules and impact of nonsense-mediated mRNA decay in human cancers
Rik G. H. Lindeboom et al.
NATURE GENETICS (2016)
Nonsense-mediated mRNA decay: novel mechanistic insights and biological impact
Evangelos D. Karousis et al.
WILEY INTERDISCIPLINARY REVIEWS-RNA (2016)
Polypyrimidine tract binding protein 1 protects mRNAs from recognition by the nonsense-mediated mRNA decay pathway
Zhiyun Ge et al.
ELIFE (2016)
Integrated genome and transcriptome sequencing of the same cell
Siddharth S. Dey et al.
NATURE BIOTECHNOLOGY (2015)
Intron retention is a widespread mechanism of tumor-suppressor inactivation
Hyunchul Jung- et al.
NATURE GENETICS (2015)
Gene expression analysis identifies global gene dosage sensitivity in cancer
Rudolf S. N. Fehrmann et al.
NATURE GENETICS (2015)
Nonsense-mediated mRNA decay: an intricate machinery that shapes transcriptomes
Soren Lykke-Andersen et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2015)
Resistance of mRNAs with AUG-proximal nonsense mutations to nonsense-mediated decay reflects variables of mRNA structure and translational activity
Francisco J. C. Pereira et al.
NUCLEIC ACIDS RESEARCH (2015)
Identification of elements in human long 3′ UTRs that inhibit nonsense-mediated decay
Kalodiah G. Toma et al.
RNA (2015)
Effect of predicted protein-truncating genetic variants on the human transcriptome
Manuel A. Rivas et al.
SCIENCE (2015)
Identification and characterization of essential genes in the human genome
Tim Wang et al.
SCIENCE (2015)
Identification and Characterization of Small Molecules That Inhibit Nonsense-Mediated RNA Decay and Suppress Nonsense p53 Mutations
Leenus Martin et al.
CANCER RESEARCH (2014)
Synonymous Mutations Frequently Act as Driver Mutations in Human Cancers
Fran Supek et al.
CELL (2014)
Patients With Colorectal Tumors With Microsatellite Instability and Large Deletions in HSP110 T17 Have Improved Response to 5-Fluorouracil-Based Chemotherapy
Ada Collura et al.
GASTROENTEROLOGY (2014)
Nonsense-mediated decay in genetic disease: Friend or foe?
Jake N. Miller et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2014)
Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation
John G. Doench et al.
NATURE BIOTECHNOLOGY (2014)
Tug-of-war between driver and passenger mutations in cancer and other adaptive processes
Christopher D. McFarland et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Dissecting Disease Inheritance Modes in a Three-Dimensional Protein Network Challenges the Guilt-by-Association Principle
Yu Guo et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2013)
Transcriptome and genome sequencing uncovers functional variation in humans
Tuuli Lappalainen et al.
NATURE (2013)
In situ sequencing for RNA analysis in preserved tissue and cells
Rongqin Ke et al.
NATURE METHODS (2013)
Early LQT2 nonsense mutation generates N-terminally truncated hERG channels with altered gating properties by the reinitiation of translation
Matthew R. Stump et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)
Rescue of nonsense mutations by amlexanox in human cells
Sara Gonzalez-Hilarion et al.
ORPHANET JOURNAL OF RARE DISEASES (2012)
Identification of hundreds of novel UPF1 target transcripts by direct determination of whole transcriptome stability
Hidenori Tani et al.
RNA BIOLOGY (2012)
A Systematic Survey of Loss-of-Function Variants in Human Protein-Coding Genes
Daniel G. MacArthur et al.
SCIENCE (2012)
A whole-genome analysis of premature termination codons
Elizabeth T. Cirulli et al.
GENOMICS (2011)
Inhibition of Nonsense-Mediated RNA Decay by the Tumor Microenvironment Promotes Tumorigenesis
Ding Wang et al.
MOLECULAR AND CELLULAR BIOLOGY (2011)
Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis
Coralie Dorard et al.
NATURE MEDICINE (2011)
Rare and Common Regulatory Variation in Population-Scale Sequenced Human Genomes
Stephen B. Montgomery et al.
PLOS GENETICS (2011)
Induction of tumour immunity by targeted inhibition of nonsense-mediated mRNA decay
Fernando Pastor et al.
NATURE (2010)
A meta-analysis of nonsense mutations causing human genetic disease
Matthew Mort et al.
HUMAN MUTATION (2008)
Failsafe nonsense-mediated mRNA decay does not detectably target eIF4E-bound mRNA
Daiki Matsuda et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2007)
Nonsense-mediated mRNA decay modulates clinical outcome of genetic disease
Mehrdad Khajavi et al.
EUROPEAN JOURNAL OF HUMAN GENETICS (2006)
The 185delAG mutation (c.68_ 69delAG) in the BRCA1 gene triggers translation reinitiation at a downstream AUG codon
Monique Buisson et al.
HUMAN MUTATION (2006)
Evidence that translation reinitiation leads to a partially functional Menkes protein containing two copper-binding sites
Marianne Paulsen et al.
AMERICAN JOURNAL OF HUMAN GENETICS (2006)
EJC-independent degradation of nonsense immunoglobulin-μ mRNA depends on 3′ UTR length
M Bühler et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2006)
Nonsense mutations in close proximity to the initiation codon fail to trigger full nonsense-mediated mRNA decay
A Inácio et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Attenuation of an amino-terminal premature stop codon mutation in the ATRX gene by an alternative mode of translational initiation
MT Howard et al.
JOURNAL OF MEDICAL GENETICS (2004)
Evidence for the widespread coupling of alternative splicing and nonsense-mediated mRNA decay in humans
BP Lewis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Mutant BRCA1 genes antagonize phenotype of wild-type BRCA1
SJ Fan et al.
ONCOGENE (2001)
The exon-exon junction complex provides a binding platform for factors involved in mRNA export and nonsense-mediated mRNA decay
H Le Hir et al.
EMBO JOURNAL (2001)