4.5 Article

Cardiotoxic Potential of Hydroxychloroquine, Chloroquine and Azithromycin in Adult Human Primary Cardiomyocytes

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

Human Heart Cardiomyocytes in Drug Discovery and Research: New Opportunities in Translational Sciences

Najah Abi-Gerges et al.

CURRENT PHARMACEUTICAL BIOTECHNOLOGY (2020)

Article Medicine, General & Internal

Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China

Dawei Wang et al.

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2020)

Article Pharmacology & Pharmacy

Acute chloroquine poisoning: A comprehensive experimental toxicology assessment of the role of diazepam

Dyfrig A. Hughes

BRITISH JOURNAL OF PHARMACOLOGY (2020)

Article Cardiac & Cardiovascular Systems

Effect of Chloroquine, Hydroxychloroquine, and Azithromycin on the Corrected QT Interval in Patients With SARS-CoV-2 Infection

Moussa Saleh et al.

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2020)

Article Cardiac & Cardiovascular Systems

Chloroquine-induced torsades de pointes in a patient with coronavirus disease 2019

Yishay Szekely et al.

HEART RHYTHM (2020)

Editorial Material Cardiac & Cardiovascular Systems

COVID-19 treatments, QT interval, and arrhythmic risk: The need for an international registry on arrhythmias

Lia Crotti et al.

HEART RHYTHM (2020)

Review Infectious Diseases

A review on possible modes of action of chloroquine/hydroxychloroquine: repurposing against SAR-CoV-2 (COVID-19) pandemic

Satyajit Tripathy et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)

Article Infectious Diseases

Hydroxychloroquine and azithromycin as a treatment of COVID-19: results of an open-label non-randomized clinical trial

Philippe Gautret et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)

Article Cardiac & Cardiovascular Systems

Human Purkinje in silico model enables mechanistic investigations into automaticity and pro-arrhythmic abnormalities

Cristian Trovato et al.

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2020)

Article Cardiac & Cardiovascular Systems

Chloroquine-induced QTc prolongation in COVID-19 patients

M. P. H. van den Broek et al.

NETHERLANDS HEART JOURNAL (2020)

Article Multidisciplinary Sciences

Multiparametric Mechanistic Profiling of Inotropic Drugs in Adult Human Primary Cardiomyocytes

Najah Abi-Gerges et al.

SCIENTIFIC REPORTS (2020)

Editorial Material Cardiac & Cardiovascular Systems

Chloroquine or Hydroxychloroquine for COVID-19: Is Cardiotoxicity a Concern?

Timothy J. Kamp et al.

JOURNAL OF THE AMERICAN HEART ASSOCIATION (2020)

Article Multidisciplinary Sciences

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

David E. Gordon et al.

NATURE (2020)

Article Cardiac & Cardiovascular Systems

Effects of hydroxychloroquine treatment on QT interval

Matthew Hooks et al.

HEART RHYTHM (2020)

Review Infectious Diseases

Macrolides and viral infections: focus on azithromycin in COVID-19 pathology

Arianna Pani et al.

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)

Review Infectious Diseases

Cardiac effects and toxicity of chloroquine: a short update

Kanigula Mubagwa

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS (2020)

Article Infectious Diseases

Treatment with hydroxychloroquine, azithromycin, and combination in patients hospitalized with COVID-19

Samia Arshad et al.

INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES (2020)

Article Medicine, Research & Experimental

Effect of Combination Therapy of Hydroxychloroquine and Azithromycin on Mortality in Patients With COVID-19

Marinella Lauriola et al.

CTS-CLINICAL AND TRANSLATIONAL SCIENCE (2020)

Article Public, Environmental & Occupational Health

Outcomes of 3,737 COVID-19 patients treated with hydroxychloroquine/azithromycin and other regimens in Marseille, France: A retrospective analysis

Jean-Christophe Lagier et al.

TRAVEL MEDICINE AND INFECTIOUS DISEASE (2020)

Article Emergency Medicine

Toxicokinetics of hydroxychloroquine following a massive overdose

Jonathan de Olano et al.

AMERICAN JOURNAL OF EMERGENCY MEDICINE (2019)

Article Cardiac & Cardiovascular Systems

Workshop Report FDA Workshop on Improving Cardiotoxicity Assessment With Human-Relevant Platforms

Li Pang et al.

CIRCULATION RESEARCH (2019)

Meeting Abstract Pharmacology & Pharmacy

Optimization of cardiac CiPA targets (hCav1.2 and hKCNQ1/hminK) on the QPatch HT automated system

Bryan J. Koci et al.

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2019)

Article Cardiac & Cardiovascular Systems

Revisiting the Cardiotoxic Effect of Chloroquine

Marguerite Blignaut et al.

CARDIOVASCULAR DRUGS AND THERAPY (2019)

Article Immunology

Systemic lupus erythematosus: Diagnosis and clinical management

Andrea Fava et al.

JOURNAL OF AUTOIMMUNITY (2019)

Review Public, Environmental & Occupational Health

Cardiac Complications Attributed to Chloroquine and Hydroxychloroquine: A Systematic Review of the Literature

Clotilde Chatre et al.

DRUG SAFETY (2018)

Meeting Abstract Cardiac & Cardiovascular Systems

HYDROXYCHLOROQUINE OVERDOSE PRESENTING AS ACQUIRED QT INTERVAL PROLONGATION AND TORSADE DE POINTES

Ifesinachi Ndukwu et al.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY (2017)

Article Cardiac & Cardiovascular Systems

Electrophysiologic Studies on the Risks and Potential Mechanism Underlying the Proarrhythmic Nature of Azithromycin

Mengdan Zhang et al.

CARDIOVASCULAR TOXICOLOGY (2017)

Article Cardiac & Cardiovascular Systems

Azithromycin Causes a Novel Proarrhythmic Syndrome

Zhenjiang Yang et al.

CIRCULATION-ARRHYTHMIA AND ELECTROPHYSIOLOGY (2017)

Article Pharmacology & Pharmacy

Human ex-vivo action potential model for pro-arrhythmia risk assessment

Guy Page et al.

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2016)

Article Pharmacology & Pharmacy

An evaluation of 30 clinical drugs against the comprehensive in vitro proarrhythmia assay (CiPA) proposed ion channel panel

William J. Crumb et al.

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2016)

Article Pharmacology & Pharmacy

The Comprehensive in Vitro Proarrhythmia Assay (CiPA) initiative Update on progress

Thomas Colatsky et al.

JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS (2016)

Letter Biotechnology & Applied Microbiology

Assessing drug safety in human tissues - what are the barriers?

Anthony Holmes et al.

NATURE REVIEWS DRUG DISCOVERY (2015)

Article Cardiac & Cardiovascular Systems

Azithromycin Can Prolong QT Interval and Suppress Ventricular Contraction, but Will Not Induce Torsade de Pointes

Hiroshi Ohara et al.

CARDIOVASCULAR TOXICOLOGY (2015)

Article Cardiac & Cardiovascular Systems

Rechanneling the cardiac proarrhythmia safety paradigm: A meeting report from the Cardiac Safety Research Consortium

Philip T. Sager et al.

AMERICAN HEART JOURNAL (2014)

Editorial Material Medicine, General & Internal

Cardiovascular risks of antibiotics

Helene Vaillant-Roussel et al.

EXERCER-LA REVUE FRANCOPHONE DE MEDECINE GENERALE (2014)

Article Primary Health Care

Azithromycin and Levofloxacin Use and Increased Risk of Cardiac Arrhythmia and Death

Gowtham A. Rao et al.

ANNALS OF FAMILY MEDICINE (2014)

Article Rheumatology

Suspected Hydroxychloroquine-Associated QT-Interval Prolongation in a Patient With Systemic Lupus Erythematosus

Nadia D. Morgan et al.

JCR-JOURNAL OF CLINICAL RHEUMATOLOGY (2013)

Review Allergy

Hydroxychloroquine: From Malaria to Autoimmunity

Ilan Ben-Zvi et al.

CLINICAL REVIEWS IN ALLERGY & IMMUNOLOGY (2012)

Article Pharmacology & Pharmacy

Validation of an in vitro contractility assay using canine ventricular myocytes

A. R. Harmer et al.

TOXICOLOGY AND APPLIED PHARMACOLOGY (2012)

Review Pharmacology & Pharmacy

Mechanisms of hypokalemia-induced ventricular arrhythmogenicity

Oleg E. Osadchii

FUNDAMENTAL & CLINICAL PHARMACOLOGY (2010)

Article Cardiac & Cardiovascular Systems

Azithromycin-induced torsade de pointes

Bien-Hsien Huang et al.

PACE-PACING AND CLINICAL ELECTROPHYSIOLOGY (2007)

Article Public, Environmental & Occupational Health

Azithromycin/Chloroquine combination does not increase cardiac instability despite an increase in monophasic action potential duration in the anesthetized guinea pig

Anthony A. Fossa et al.

AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE (2007)

Article Cardiac & Cardiovascular Systems

Azithromycin as a cause of QT-interval prolongation and torsade de pointes in the absence of other known precipitating factors

Anna Kezerashvili et al.

JOURNAL OF INTERVENTIONAL CARDIAC ELECTROPHYSIOLOGY (2007)

Article Cardiac & Cardiovascular Systems

Pro-arrhythmic effects of amiodarone and concomitant rate-control medication

Jan Wilko Schrickel et al.

EUROPACE (2006)

Article Pharmacology & Pharmacy

Inhibition of hERG K+ currents by antimalarial drugs in stably transfected HEK293 cells

M Traebert et al.

EUROPEAN JOURNAL OF PHARMACOLOGY (2004)

Article Cardiac & Cardiovascular Systems

Fever as a precipitant of idiopathic ventricular fibrillation in patients with normal hearts

JL Pasquié et al.

JOURNAL OF CARDIOVASCULAR ELECTROPHYSIOLOGY (2004)