Journal
TETRAHEDRON LETTERS
Volume 65, Issue -, Pages -Publisher
PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2020.152748
Keywords
Sulfenylation; Thiosulfonate; Indole; Lewis acid; C-S bond
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The activation of 8-quinolinethiosulfonates by zinc chloride enables the C3-alkylsulfenylation of indoles at room temperature under aerobic conditions, which is compatible with substrates containing various functional groups.
The activation of 8-quinolinethiosulfonates by zinc chloride promotes the usually difficult to achieve C3-alkylsulfenylation of indoles at room temperature under aerobic conditions. This strategy is compatible with substrates containing various functional groups. (C) 2021 Elsevier Ltd. All rights reserved.
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