4.4 Article

Aminomethylation of imidazopyridines using N,N-dimethylformamide as an aminomethylating reagent under Cu(II)-catalysis

Journal

TETRAHEDRON LETTERS
Volume 61, Issue 49, Pages -

Publisher

PERGAMON-ELSEVIER SCIENCE LTD
DOI: 10.1016/j.tetlet.2020.152581

Keywords

Aminomethylation; Imidazopyridine; DMF; Cu(II)-catalysis; Radical

Funding

  1. CSIR, New Delhi [02(0307)/17/EMR-II]
  2. UGC-New Delhi (UGC-JRF)

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N,N-Dimethylformamide has been explored as an aminomethylating reagent in the functionalization of imidazopyridine under Cu(II)-catalysis. A library of aminomethylated imidazopyridines with broad functionalities was synthesized in good yields. (C) 2020 Elsevier Ltd. All rights reserved.

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