Journal
STEM CELL RESEARCH
Volume 50, Issue -, Pages -Publisher
ELSEVIER
DOI: 10.1016/j.scr.2020.102123
Keywords
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Funding
- National Natural Science Foundation of China [81660130]
- Natural Science Foundation of Gansu Province, China [18JR3RA045]
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A stem cell line GWCMCi001-A was established from PBMCs of a 4-year-old male patient with IgAN using episomal plasmids, serving as an ideal in vitro model to study the pathogenesis of IgAN.
Immunoglobulin A nephropathy (IgAN) is a common primary glomerular disease contributing to end-stage renal failure. In this study, the induced pluripotent stem cell line GWCMCi001-A from PBMCs of a 4-year-old male patient with IgAN using the episomal plasmids was established, which is an ideal in vitro model to understand the exact pathogenesis of IgAN.
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