Related references
Note: Only part of the references are listed.Nebulised ALX-0171 for respiratory syncytial virus lower respiratory tract infection in hospitalised children: a double-blind, randomised, placebo-controlled, phase 2b trial
Steve Cunningham et al.
LANCET RESPIRATORY MEDICINE (2021)
Cryo-EM structure of the 2019-nCoV spike in the prefusion conformation
Daniel Wrapp et al.
SCIENCE (2020)
Structural and Functional Basis of SARS-CoV-2 Entry by Using Human ACE2
Qihui Wang et al.
CELL (2020)
Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies
Daniel Wrapp et al.
CELL (2020)
Structure, Function, and Antigenicity of the SARS-CoV-2 Spike Glycoprotein
Alexandra C. Walls et al.
CELL (2020)
SARS-CoV-2 Cell Entry Depends on ACE2 and TMPRSS2 and Is Blocked by a Clinically Proven Protease Inhibitor
Markus Hoffmann et al.
CELL (2020)
An Infectious cDNA Clone of SARS-CoV-2
Xuping Xie et al.
CELL HOST & MICROBE (2020)
Cross-neutralization ofSARS-CoV-2 by a human monoclonal SARS-CoV antibody
Dora Pinto et al.
NATURE (2020)
Structure of the SARS-CoV-2 spike receptor-binding domain bound to the ACE2 receptor
Jun Lan et al.
NATURE (2020)
Deep Mutational Scanning of SARS-CoV-2 Receptor Binding Domain Reveals Constraints on Folding and ACE2 Binding
Tyler N. Starr et al.
CELL (2020)
Structures of Human Antibodies Bound to SARS-CoV-2 Spike Reveal Common Epitopes and Recurrent Features of Antibodies
Christopher O. Barnes et al.
CELL (2020)
Neutralization of SARS-CoV-2 by Destruction of the Prefusion Spike
Jiandong Huo et al.
CELL HOST & MICROBE (2020)
Neutralizing Antibody and Soluble ACE2 Inhibition of a Replication-Competent VSV-SARS-CoV-2 and a Clinical Isolate of SARS-CoV-2
James Brett Case et al.
CELL HOST & MICROBE (2020)
Measuring SARS-CoV-2 neutralizing antibody activity using pseudotyped and chimeric viruses
Fabian Schmidt et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2020)
SARS-coronavirus-2 replication in Vero E6 cells: replication kinetics, rapid adaptation and cytopathology
Natacha S. Ogando et al.
JOURNAL OF GENERAL VIROLOGY (2020)
Neutralizing nanobodies bind SARS-CoV-2 spike RBD and block interaction with ACE2
Jiangdong Huo et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2020)
Antibody cocktail to SARS-CoV-2 spike protein prevents rapid mutational escape seen with individual antibodies
Alina Baum et al.
SCIENCE (2020)
Isolation of potent SARS-CoV-2 neutralizing antibodies and protection from disease in a small animal model
Thomas F. Rogers et al.
SCIENCE (2020)
Structure-based design of prefusion-stabilized SARS-CoV-2 spikes
Ching-Lin Hsieh et al.
SCIENCE (2020)
Structural basis for neutralization of SARS-CoV-2 and SARS-CoV by a potent therapeutic antibody
Zhe Lv et al.
SCIENCE (2020)
Structural basis of a shared antibody response to SARS-CoV-2
Meng Yuan et al.
SCIENCE (2020)
Receptor binding and priming of the spike protein of SARS-CoV-2 for membrane fusion
Donald J. Benton et al.
NATURE (2020)
Structures and distributions of SARS-CoV-2 spike proteins on intact virions
Zunlong Ke et al.
NATURE (2020)
In situ structural analysis of SARS-CoV-2 spike reveals flexibility mediated by three hinges
Beata Turonova et al.
SCIENCE (2020)
Ultrapotent human antibodies protect against SARS-CoV-2 challenge via multiple mechanisms
M. Alejandra Tortorici et al.
SCIENCE (2020)
The Architecture of Inactivated SARS-CoV-2 with Postfusion Spikes Revealed by Cryo-EM and Cryo-ET
Chuang Liu et al.
STRUCTURE (2020)
An alpaca nanobody neutralizes SARS-CoV-2 by blocking receptor interaction
Leo Hanke et al.
NATURE COMMUNICATIONS (2020)
Cross-Neutralization of a SARS-CoV-2 Antibody to a Functionally Conserved Site Is Mediated by Avidity
Hejun Liu et al.
IMMUNITY (2020)
Infection fatality rate of SARS-CoV2 in a super-spreading event in Germany
Hendrik Streeck et al.
NATURE COMMUNICATIONS (2020)
An ultrapotent synthetic nanobody neutralizes SARS-CoV-2 by stabilizing inactive Spike
Michael Schoof et al.
SCIENCE (2020)
Selection, biophysical and structural analysis of synthetic nanobodies that effectively neutralize SARS-CoV-2
Tania F. Custodio et al.
NATURE COMMUNICATIONS (2020)
Escape from neutralizing antibodies by SARS-CoV-2 spike protein variants
Yiska Weisblum et al.
ELIFE (2020)
Unexpected Receptor Functional Mimicry Elucidates Activation of Coronavirus Fusion
Alexandra C. Walls et al.
CELL (2019)
Real-time cryo-electron microscopy data preprocessing with Warp
Dimitry Tegunov et al.
NATURE METHODS (2019)
Caplacizumab Treatment for Acquired Thrombotic Thrombocytopenic Purpura
M. Scully et al.
NEW ENGLAND JOURNAL OF MEDICINE (2019)
Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry
Yushun Wan et al.
JOURNAL OF VIROLOGY (2019)
Guidelines for using Bsoft for high resolution reconstruction and validation of biomolecular structures from electron micrographs
J. Bernard Heymann
PROTEIN SCIENCE (2018)
UCSF ChimeraX: Meeting modern challenges in visualization and analysis
Thomas D. Goddard et al.
PROTEIN SCIENCE (2018)
Exploiting Nanobodies' Singular Traits
Jessica R. Ingram et al.
ANNUAL REVIEW OF IMMUNOLOGY, VOL 36 (2018)
EzColocalization: An ImageJ plugin for visualizing and measuring colocalization in cells and organisms
Weston Stauffer et al.
SCIENTIFIC REPORTS (2018)
Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2
Wenfei Song et al.
PLOS PATHOGENS (2018)
Universal protection against influenza infection by a multidomain antibody to influenza hemagglutinin
Nick S. Laursen et al.
SCIENCE (2018)
New tools for automated high-resolution cryo-EM structure determination in RELION-3
Jasenko Zivanov et al.
ELIFE (2018)
Past, Present and Future Approaches to the Prevention and Treatment of Respiratory Syncytial Virus Infection in Children
Eric A. F. Simoes et al.
INFECTIOUS DISEASES AND THERAPY (2018)
cryoSPARC: algorithms for rapid unsupervised cryo-EM structure determination
Ali Punjani et al.
NATURE METHODS (2017)
Addressing preferred specimen orientation in single-particle cryo-EM through tilting
Yong Zi Tan et al.
NATURE METHODS (2017)
Immunogenicity and structures of a rationally designed prefusion MERS-CoV spike antigen
Jesper Pallesen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2017)
Bivalent llama single-Domain antibody Fragments against Tumor necrosis Factor have Picomolar Potencies due to intramolecular interactions
Els Beirnaert et al.
FRONTIERS IN IMMUNOLOGY (2017)
Generation and Characterization of ALX-0171, a Potent Novel Therapeutic Nanobody for the Treatment of Respiratory Syncytial Virus Infection
Laurent Detalle et al.
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY (2016)
A single domain antibody fragment that recognizes the adaptor ASC defines the role of ASC domains in inflammasome assembly
Florian I. Schmidt et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2016)
Structure, Function, and Evolution of Coronavirus Spike Proteins
Fang Li
ANNUAL REVIEW OF VIROLOGY, VOL 3 (2016)
Camelid Ig V genes reveal significant human homology not seen in therapeutic target genes, providing for a powerful therapeutic antibody platform
Alex Klarenbeek et al.
MABS (2015)
EMRinger: side chain directed model and map validation for 3D cryo-electron microscopy
Benjamin A. Barad et al.
NATURE METHODS (2015)
A robust pipeline for rapid production of versatile nanobody repertoires
Peter C. Fridy et al.
NATURE METHODS (2014)
Site-specific C-terminal and internal loop labeling of proteins using sortase-mediated reactions
Carla P. Guimaraes et al.
NATURE PROTOCOLS (2013)
Strategies for extended serum half-life of protein therapeutics
Roland E. Kontermann
CURRENT OPINION IN BIOTECHNOLOGY (2011)
Different host cell proteases activate the SARS-coronavirus spike-protein for cell-cell and virus-cell fusion
Graham Simmons et al.
VIROLOGY (2011)
MolProbity: all-atom structure validation for macromolecular crystallography
Vincent B. Chen et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Features and development of Coot
P. Emsley et al.
ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY (2010)
PHENIX: a comprehensive Python-based system for macromolecular structure solution
Paul D. Adams et al.
ACTA CRYSTALLOGRAPHICA SECTION D-STRUCTURAL BIOLOGY (2010)
Jalview Version 2-a multiple sequence alignment editor and analysis workbench
Andrew M. Waterhouse et al.
BIOINFORMATICS (2009)
General Strategy to Humanize a Camelid Single-domain Antibody and Identification of a Universal Humanized Nanobody Scaffold
Cecile Vincke et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Inference of macromolecular assemblies from crystalline state
Evgeny Krissinel et al.
JOURNAL OF MOLECULAR BIOLOGY (2007)
Phaser crystallographic software
Airlie J. McCoy et al.
JOURNAL OF APPLIED CRYSTALLOGRAPHY (2007)
Human monoclonal antibody combination against SARS coronavirus: Synergy and coverage of escape mutants
Jan ter Meulen et al.
PLOS MEDICINE (2006)
Share Paper
