Lean NAFLD: an underrecognized and challenging disorder in medicine

Classically, Non-Alcoholic Fatty Liver Disease (NAFLD) has been thought to be driven by excessive weight gain and obesity. The overall greater awareness of this disorder has led to its recognition in patients with normal body mass index (BMI). Ongoing research has helped to better understand potential causes of Lean NAFLD, the risks for more advanced disease, and potential therapies. Here we review the recent literature on prevalence, risk factors, severity of disease, and potential therapeutic interventions.

Automated summary

NAFLD is not only associated with obesity but can also occur in individuals with normal body weight. Research on Lean NAFLD helps to better understand the risk factors, disease progression, and potential treatments for this condition.