4.7 Review

Application areas of 3D bioprinting

Journal

DRUG DISCOVERY TODAY
Volume 21, Issue 8, Pages 1257-1271

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.drudis.2016.04.006

Keywords

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Funding

  1. National Science Foundation CMMI Awards [1349716, 1462232]
  2. Diabetes in Action Research and Education Foundation [426]
  3. China Scholarship Council [201308360128]
  4. Directorate For Engineering
  5. Div Of Civil, Mechanical, & Manufact Inn [1624515, 1600118] Funding Source: National Science Foundation
  6. Div Of Civil, Mechanical, & Manufact Inn
  7. Directorate For Engineering [1349716, 1462232] Funding Source: National Science Foundation

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Three dimensional (3D) bioprinting has been a powerful tool in patterning and precisely placing biologics, including living cells, nucleic acids, drug particles, proteins and growth factors, to recapitulate tissue anatomy, biology and physiology. Since the first time of cytoscribing cells demonstrated in 1986, bioprinting has made a substantial leap forward, particularly in the past 10 years, and it has been widely used in fabrication of living tissues for various application areas. The technology has been recently commercialized by several emerging businesses, and bioprinters and bioprinted tissues have gained significant interest in medicine and pharmaceutics. This Keynote review presents the bioprinting technology and covers a first-time comprehensive overview of its application areas from tissue engineering and regenerative medicine to pharmaceutics and cancer research.

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