Journal
PHYTOTHERAPY RESEARCH
Volume 35, Issue 5, Pages 2296-2316Publisher
WILEY
DOI: 10.1002/ptr.6948
Keywords
algal metabolites; antiviral; COVID-19; HIV; HSV; SARS-CoV-2
Categories
Funding
- UGC, India
- DAVV, Indore
- IIT Indore
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The Covid-19 pandemic has significantly impacted global health, with increasing confirmed cases and deaths. While no specific medicine or vaccine is available yet, research is ongoing, including the development of vaccines and exploration of herbal remedies. India's use of herbal remedies as a preventive measure has contributed to a lower severity of Covid-19 compared to other countries, highlighting the potential of natural treatments in combating the virus.
Covid-19 pandemic severely affected human health worldwide. Till October 19, 2020, total confirmed patients of COVID-19 are 39,944,882, whereas 1,111,998 people died across the globe. Till to date, we do not have any specific medicine and/or vaccine to treat COVID-19; however, research is still going on at war footing. So far vaccine development is concerned, here it is noteworthy that till now three major variants (named A, B, and C) of severe acute respiratory syndrome-coronavirus2 (SARS-CoV-2) have been recognized. Increased mutational rate and formation of new viral variants may increase the attrition rate of vaccines and/or candidate chemotherapies. Herbal remedies are chemical cocktails, thus open another avenue for effective antiviral therapeutics development. In fact, India is a large country, which is densely populated, but the overall severity of COVID-19 per million populations is lesser than any other country of the world. One of the major reasons for the aforesaid difference is the use of herbal remedies by the Government of India as a preventive measure for COVID-19. Therefore, the present review focuses on the epidemiology and molecular pathogenesis of COVID-19 and explores algal metabolites for their antiviral properties.
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