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Olanzapine augments the effect of selective serotonin reuptake inhibitors by suppressing GABAergic inhibition via antagonism of 5-HT6 receptors in the dorsal raphe nucleus
Nozomi Asaoka et al.
NEUROPHARMACOLOGY (2015)
Increased Serotonin Transporter Expression Reduces Fear and Recruitment of Parvalbumin Interneurons of the Amygdala
Marco Bocchio et al.
NEUROPSYCHOPHARMACOLOGY (2015)
Mice Lacking the Serotonin Htr2B Receptor Gene Present an Antipsychotic-Sensitive Schizophrenic-Like Phenotype
Pothitos M. Pitychoutis et al.
NEUROPSYCHOPHARMACOLOGY (2015)
Individual Differences in Impulsive Action Reflect Variation in the Cortical Serotonin 5-HT2A Receptor System
Latham H. L. Fink et al.
NEUROPSYCHOPHARMACOLOGY (2015)
DECONSTRUCTING 5-HT6 RECEPTOR EFFECTS ON STRIATAL CIRCUIT FUNCTION
D. Eskenazi et al.
NEUROSCIENCE (2015)
DISTRIBUTION OF SEROTONIN RECEPTOR 5-HT6 mRNA IN RAT NEURONAL SUBPOPULATIONS: A DOUBLE IN SITU HYBRIDIZATION STUDY
L. Helboe et al.
NEUROSCIENCE (2015)
SEROTONIN-2C AND-2A RECEPTOR CO-EXPRESSION ON CELLS IN THE RAT MEDIAL PREFRONTAL CORTEX
C. Nocjar et al.
NEUROSCIENCE (2015)
THE INS AND OUTS OF THE STRIATUM: ROLE IN DRUG ADDICTION
L. M. Yager et al.
NEUROSCIENCE (2015)
Activation of serotonin 5-HT2C receptor suppresses behavioral sensitization and naloxone-precipitated withdrawal symptoms in heroin-treated mice
Xian Wu et al.
NEUROSCIENCE LETTERS (2015)
Structure and function of serotonin G protein-coupled receptors
John D. McCorvy et al.
PHARMACOLOGY & THERAPEUTICS (2015)
Vortioxetine, a novel antidepressant with multimodal activity: Review of preclinical and clinical data
Connie Sanchez et al.
PHARMACOLOGY & THERAPEUTICS (2015)
mTOR IN BRAIN PHYSIOLOGY AND PATHOLOGIES
Joel Bockaert et al.
PHYSIOLOGICAL REVIEWS (2015)
Pathways and Barriers for Ion Translocation through the 5-HT3A Receptor Channel
Danilo Di Maio et al.
PLOS ONE (2015)
Attenuation of cocaine-induced reinstatement of drug seeking in squirrel monkeys by direct and indirect activation of 5-HT2C receptors
Daniela Rueedi-Bettschen et al.
PSYCHOPHARMACOLOGY (2015)
Alpha-smooth muscle actin and serotonin receptors 2A and 2B in dogs with myxomatous mitral valve disease
S. E. Cremer et al.
RESEARCH IN VETERINARY SCIENCE (2015)
Yif1B Is Involved in the Anterograde Traffic Pathway and the Golgi Architecture
Jeanine Alterio et al.
TRAFFIC (2015)
The phospholipase D superfamily as therapeutic targets
Michael A. Frohman
TRENDS IN PHARMACOLOGICAL SCIENCES (2015)
Serotonin markers show altered transcription levels in an experimental pig model of mitral regurgitation
S. E. Cremer et al.
VETERINARY JOURNAL (2015)
Design, Synthesis, and Evaluation of Tetrasubstituted Pyridines as Potent 5-HT2C Receptor Agonists
Guy Rouquet et al.
ACS MEDICINAL CHEMISTRY LETTERS (2015)
Selective pharmacological blockade of the 5-HT7 receptor attenuates light and 8-OH-DPAT induced phase shifts of mouse circadian wheel running activity
Jonathan Shelton et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2015)
Long-lasting beneficial effects of central serotonin receptor 7 stimulation in female mice modeling Rett syndrome
Bianca De Filippis et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2015)
Activation of 5-HT7 receptor stimulates neurite elongation through mTOR, Cdc42 and actin filaments dynamics
Luisa Speranza et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2015)
Novel agonists for serotonin 5-HT7 receptors reverse metabotropic glutamate receptor-mediated long-term depression in the hippocampus of wild-type and Fmr1 KO mice, a model of Fragile X Syndrome
Lara Costa et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2015)
Identification of essential residues for binding and activation in the human 5-HT7(a) serotonin receptor by molecular modeling and site-directed mutagenesis
Agata Antonina Rita Impellizzeri et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2015)
Cognitive Impairment Induced by Delta9-tetrahydrocannabinol Occurs through Heteromers between Cannabinoid CB1 and Serotonin 5-HT2A Receptors
Xavier Vinals et al.
PLOS BIOLOGY (2015)
5-HT2B Receptor Antagonists Inhibit Fibrosis and Protect from RV Heart Failure
Wiebke Janssen et al.
BIOMED RESEARCH INTERNATIONAL (2015)
Distribution of 5-HT3, 5-HT4, and 5-HT7 Receptors Along the Human Colon
Nor S. Yaakob et al.
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY (2015)
The 5-HT7 receptor as a potential target for treating drug and alcohol abuse
Sheketha R. Hauser et al.
FRONTIERS IN NEUROSCIENCE (2015)
5-HT6 receptor agonism facilitates emotional learning
Marcela Pereira et al.
FRONTIERS IN PHARMACOLOGY (2015)
Serotonin 2a Receptor and Serotonin la Receptor Interact Within the Medial Prefrontal Cortex During Recognition Memory in Mice
Juan F. Morici et al.
FRONTIERS IN PHARMACOLOGY (2015)
Central serotonin-2A (5-HT2A) receptor dysfunction in depression and epilepsy: the missing link?
Bruno P. Guiard et al.
FRONTIERS IN PHARMACOLOGY (2015)
Serotonin, neural markers, and memory
Alfredo Meneses
FRONTIERS IN PHARMACOLOGY (2015)
The role of serotonin 5-HT2A receptors in memory and cognition
Gongliang Zhang et al.
FRONTIERS IN PHARMACOLOGY (2015)
The role of serotonin and its receptors in activation of immune responses and inflammation
M. S. Shajib et al.
ACTA PHYSIOLOGICA (2015)
Serotonin2C receptors modulate dopamine transmission in the nucleus accumbens independently of dopamine release: behavioral, neurochemical and molecular studies with cocaine
Adeline Cathala et al.
ADDICTION BIOLOGY (2015)
Improved Anti-Emetic Efficacy of 5-HT3 Receptor Antagonists in Cancer Patients with Genetic Polymorphisms of ABCB1 (MDR1) Drug Transporter
Teuta Zoto et al.
BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY (2015)
Serotonin 5-HT4 receptors and forebrain cholinergic system: receptor expression in identified cell populations
Raul Penas-Cazorla et al.
BRAIN STRUCTURE & FUNCTION (2015)
5-HT6 Receptor Recruitment of mTOR Modulates Seizure Activity in Epilepsy
Liang Wang et al.
MOLECULAR NEUROBIOLOGY (2015)
Pilot study of Biomarkers for predicting effectiveness of ramosetron in diarrhea-predominant irritable bowel syndrome: expression of S100A10 and polymorphisms of TPH1
A. Shiotani et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2015)
Pharmacological Characterization of 5-HT1A Autoreceptor-Coupled GIRK Channels in Rat Dorsal Raphe 5-HT Neurons
Alberto Montalbano et al.
PLOS ONE (2015)
Critical involvement of 5-HT2C receptor function in amphetamine-induced 50-kHz ultrasonic vocalizations in rats
Markus Woehr et al.
PSYCHOPHARMACOLOGY (2015)
Investigating interactions between phentermine, dexfenfluramine, and 5-HT2C agonists, on food intake in the rat
Andrew J. Grottick et al.
PSYCHOPHARMACOLOGY (2015)
Decrease of mRNA Editing after Spinal Cord Injury is Caused by Down-regulation of ADAR2 that is Triggered by Inflammatory Response
Antonio Fabio Di Narzo et al.
SCIENTIFIC REPORTS (2015)
Serotonin 5-HT2 Receptor Interactions with Dopamine Function: Implications for Therapeutics in Cocaine Use Disorder
Leonard L. Howell et al.
PHARMACOLOGICAL REVIEWS (2015)
Fulfilling the Promise of Biased G Protein-Coupled Receptor Agonism
Louis M. Luttrell et al.
MOLECULAR PHARMACOLOGY (2015)
Detection of New Biased Agonists for the Serotonin 5-HT2A Receptor: Modeling and Experimental Validation
Maria Marti-Solano et al.
MOLECULAR PHARMACOLOGY (2015)
Native Serotonin 5-HT2C Receptors Are Expressed as Homodimers on the Apical Surface of Choroid Plexus Epithelial Cells
Katharine Herrick-Davis et al.
MOLECULAR PHARMACOLOGY (2015)
5-HT is a potent relaxant in rat superior mesenteric veins
Stephanie W. Watts et al.
PHARMACOLOGY RESEARCH & PERSPECTIVES (2015)
Synthesis and Structure-Activity Relationships of N-Benzyl Phenethylamines as 5-HT2A/2c Agonists
Martin Hansen et al.
ACS CHEMICAL NEUROSCIENCE (2014)
Association Between HTR7 Genetic Polymorphisms and Alcohol Dependence, Using the Alcohol Use Disorders Identification Test (AUDIT)
Jeong-Hyun Kim et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2014)
Systematic review with meta-analysis: highly selective 5-HT4 agonists (prucalopride, velusetrag or naronapride) in chronic constipation
A. Shin et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2014)
Transglutaminase 2-mediated serotonylation in pulmonary hypertension
K. C. Penumatsa et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2014)
Lurasidone as Adjunctive Therapy With Lithium or Valproate for the Treatment of Bipolar I Depression: A Randomized, Double-Blind, Placebo-Controlled Study
Antony Loebel et al.
AMERICAN JOURNAL OF PSYCHIATRY (2014)
Lurasidone Monotherapy in the Treatment of Bipolar I Depression: A Randomized, Double-Blind, Placebo-Controlled Study
Antony Loebel et al.
AMERICAN JOURNAL OF PSYCHIATRY (2014)
Effect of Sarizotan, a 5-HT1a and D2-Like Receptor Agonist, on Respiration in Three Mouse Models of Rett Syndrome
Ana P. Abdala et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2014)
Selective Serotonin Reuptake Inhibitors for the Treatment of Irritable Bowel Syndrome
Andrew W. Bundeff et al.
ANNALS OF PHARMACOTHERAPY (2014)
Systemic administration and local microinjection into the central nervous system of the 5-HT7 receptor agonist LP-211 modify the sleep-wake cycle in the rat
Jaime M. Monti et al.
BEHAVIOURAL BRAIN RESEARCH (2014)
Reductions of p11 and 5-HT1B Receptor Availability in Limbic Brain Regions in Cocaine Dependence
Per Svenningsson
BIOLOGICAL PSYCHIATRY (2014)
Discovery and pharmacological profile of new hydrophilic 5-HT4 receptor antagonists
Bjarne Brudeli et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
The discovery of diazepinone-based 5-HT3 receptor partial agonists
David D. Manning et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2014)
The serotonin transporter gene polymorphism (5-HTTLPR) and irritable bowel syndrome: a meta-analysis of 25 studies
Zhi-Feng Zhang et al.
BMC GASTROENTEROLOGY (2014)
Expression analysis of genes and pathways associated with liver metastases of the uveal melanoma
Yuanyuan Zhang et al.
BMC MEDICAL GENETICS (2014)
Functional expression of 5-HT7 receptor on the substantia gelatinosa neurons of the trigeminal subnucleus caudalis in mice
Eun Ju Yang et al.
BRAIN RESEARCH (2014)
Efficacy of palonosetron for the prevention of postoperative nausea and vomiting: a randomized, double-blinded, placebo-controlled trial
H. R. Chun et al.
BRITISH JOURNAL OF ANAESTHESIA (2014)
Deletion of Serotonin 2B Receptor Provokes Structural Alterations of Mouse Dental Tissues
Sasha Dimitrova-Nakov et al.
CALCIFIED TISSUE INTERNATIONAL (2014)
Phosphodiesterase 4 interacts with the 5-HT4(b) receptor to regulate cAMP signaling
S. Weninger et al.
CELLULAR SIGNALLING (2014)
Tissue transglutaminase promotes serotonin-induced AKT signaling and mitogenesis in pulmonary vascular smooth muscle cells
Krishna Penumatsa et al.
CELLULAR SIGNALLING (2014)
Stimulation of 5-HT4 receptor enhances differentiation of mouse induced pluripotent stem cells into neural progenitor cells
Toshiaki Ishizuka et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2014)
Association of ABCB1 Polymorphisms With the Efficacy of Ondansetron in Chemotherapy-induced Nausea and Vomiting
Hui He et al.
CLINICAL THERAPEUTICS (2014)
Role(s) of the 5-HT2C Receptor in the Development of Maximal Dentate Activation in the Hippocampus of Anesthetized Rats
Gergely Orban et al.
CNS NEUROSCIENCE & THERAPEUTICS (2014)
Interplay between Serotonin 5-HT1A and 5-HT7 Receptors in Depressive Disorders
Vladimir S. Naumenko et al.
CNS NEUROSCIENCE & THERAPEUTICS (2014)
Effectiveness of lurasidone in schizophrenia or schizoaffective patients switched from other antipsychotics: a 6-month, open-label, extension study
Leslie Citrome et al.
CNS SPECTRUMS (2014)
Transcriptional Dys-regulation in Anxiety and Major Depression: 5-HT1A Gene Promoter Architecture as a Therapeutic Opportunity
Paul R. Albert et al.
CURRENT PHARMACEUTICAL DESIGN (2014)
Serotonin 5-HT4 Receptors: A New Strategy for Developing Fast Acting Antidepressants?
Rebeca Vidal et al.
CURRENT PHARMACEUTICAL DESIGN (2014)
The serotonin 6 receptor controls neuronal migration during corticogenesis via a ligand-independent Cdk5-dependent mechanism
Moritz Jacobshagen et al.
DEVELOPMENT (2014)
Pathophysiological and neurochemical mechanisms of postoperative nausea and vomiting
Charles C. Horn et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
Looking beyond 5-HT3 receptors: A review of the wider role of serotonin in the pharmacology of nausea and vomiting
Kevin D. Johnston et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
Molecular mechanisms of 5-HT3 and NK1 receptor antagonists in prevention of emesis
Camilo Rojas et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
Nausea and the quest for the perfect anti-emetic
Paul L. R. Andrews et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2014)
ASP5736, a novel 5-HT5A receptor antagonist, ameliorates positive symptoms and cognitive impairment in animal models of schizophrenia
Mayako Yamazaki et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2014)
Coupling of serotonergic input to NMDA receptor-phosphorylation following peripheral nerve injury via rapid, synaptic up-regulation of ND2
Zigor Aira et al.
EXPERIMENTAL NEUROLOGY (2014)
Pharmacological rescue of Ras signaling, GluA1-dependent synaptic plasticity, and learning deficits in a fragile X model
Chae-Seok Lim et al.
GENES & DEVELOPMENT (2014)
Pharmacological reduction of mucosal but not neuronal serotonin opposes inflammation in mouse intestine
Kara Gross Margolis et al.
GUT (2014)
A unique gene expression signature associated with serotonin 2C receptor RNA editing in the prefrontal cortex and altered in suicide
Antonio Fabio Di Narzo et al.
HUMAN MOLECULAR GENETICS (2014)
Serotonin 5-HT7 Receptor Is Critically Involved in Acute and Chronic Inflammation of the Gastrointestinal Tract
Daria Guseva et al.
INFLAMMATORY BOWEL DISEASES (2014)
Enhancement of alcohol drinking in mice depends on alterations in RNA editing of serotonin 2C receptors
Yoshihisa Watanabe et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2014)
Methylation at a transcription factor-binding site on the 5-HT1A receptor gene correlates with negative symptom treatment response in first episode schizophrenia
Hao Tang et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2014)
The Developmental Basis of Epigenetic Regulation of HTR2A and Psychiatric Outcomes
Alison G. Paquette et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2014)
Serotonin 2A receptor agonist binding in the human brain with [11C]Cimbi-36
Anders Ettrup et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2014)
Dual Histamine H3R/Serotonin 5-HT4R Ligands with Antiamnesic Properties: Pharmacophore-Based Virtual Screening and Polypharmacology
Alban Lepailleur et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2014)
Distribution of Serotonin 4(a) Receptors in the juvenile Rat Brain and Spinal Cord
Beato Suwa et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2014)
Leptin at 20: an overview
Jeffrey Friedman
JOURNAL OF ENDOCRINOLOGY (2014)
Multiparameter Optimization in CNS Drug Discovery: Design of Pyrimido[4,5-d]azepines as Potent 5-Hydroxytryptamine 2C (5-HT2C) Receptor Agonists with Exquisite Functional Selectivity over 5-HT2A and 5-HT2B Receptors
R. Ian Storer et al.
JOURNAL OF MEDICINAL CHEMISTRY (2014)
5-HT7 Receptors Are Involved in Neurogenic Dural Vasodilatation in an Experimental Model of Migraine
Xiaojuan Wang et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2014)
Comparative effect of lurasidone and blonanserin on cortical glutamate, dopamine, and acetylcholine efflux: role of relative serotonin (5-HT) 2A and DA D2 antagonism and 5-HT1A partial agonism
Mei Huang et al.
JOURNAL OF NEUROCHEMISTRY (2014)
Mice with Compromised 5-HTT Function Lack Phosphotyrosine-Mediated Inhibitory Control over Prefrontal 5-HT Responses
Nathalie M. Goodfellow et al.
JOURNAL OF NEUROSCIENCE (2014)
In Vivo Evaluation of 18F-MNI698: An 18F-Labeled Radiotracer for Imaging of Serotonin 4 Receptors in Brain
Adriana Alexandre S. Tavares et al.
JOURNAL OF NUCLEAR MEDICINE (2014)
Physiological underpinnings of irritable bowel syndrome: neurohormonal mechanisms
Michael Camilleri
JOURNAL OF PHYSIOLOGY-LONDON (2014)
Characterization of Protein Serotonylation via Bioorthogonal Labeling and Enrichment
Jason Ching-Yao Lin et al.
JOURNAL OF PROTEOME RESEARCH (2014)
A 6-week randomized, double-blind, placebo-controlled, comparator referenced trial of vabicaserin in acute schizophrenia
Joan H. Q. Shen et al.
JOURNAL OF PSYCHIATRIC RESEARCH (2014)
Role of melatonin, serotonin 2B, and serotonin 2C receptors in modulating the firing activity of rat dopamine neurons
Franck Chenu et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2014)
Quantitative Phosphoproteomics Unravels Biased Phosphorylation of Serotonin 2A Receptor at Ser280 by Hallucinogenic versus Nonhallucinogenic Agonists
Samah Karaki et al.
MOLECULAR & CELLULAR PROTEOMICS (2014)
Pimavanserin as treatment for Parkinson's disease psychosis
Susan H. Fox
LANCET (2014)
Safety and efficacy of idalopirdine, a 5-HT6 receptor antagonist, in patients with moderate Alzheimer's disease (LADDER): a randomised, double-blind, placebo-controlled phase 2 trial
David Wilkinson et al.
LANCET NEUROLOGY (2014)
X-ray structure of the mouse serotonin 5-HT3 receptor
Gherici Hassaine et al.
NATURE (2014)
Cdk5 induces constitutive activation of 5-HT6 receptors to promote neurite growth
Fanny Duhr et al.
NATURE CHEMICAL BIOLOGY (2014)
NEURONAL DIFFERENTIATION 5-HT6R can do it alone
Jinsoo Seo et al.
NATURE CHEMICAL BIOLOGY (2014)
Improving cognition in schizophrenia with antipsychotics that elicit neurogenesis through 5-HT1A receptor activation
Rudy Schreiber et al.
NEUROBIOLOGY OF LEARNING AND MEMORY (2014)
Novel partial 5HT3 agonist pumosetrag reduces acid reflux events in uninvestigated GERD patients after a standard refluxogenic meal: a randomized, double-blind, placebo-controlled pharmacodynamic study
R. S. Choung et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2014)
Effect of prucalopride on symptoms of chronic constipation
J. Tack et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2014)
Regionally dependent neuromuscular functions of motilin and 5-HT4 receptors in human isolated esophageal body and gastric fundus
J. Broad et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2014)
Extensive projections of myenteric serotonergic neurons suggest they comprise the central processing unit in the colon
T. Okamoto et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2014)
Influence of a new 5-HT4 receptor partial agonist, YKP10811, on visceral hypersensitivity in rats triggered by stress and inflammation
M. Gilet et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2014)
Drugs acting at 5-HT4, D2, motilin, and ghrelin receptors differ markedly in how they affect neuromuscular functions in human isolated stomach
J. Broad et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2014)
Prucalopride decreases esophageal acid exposure and accelerates gastric emptying in healthy subjects
B. F. Kessing et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2014)
5-HT7 Receptors and Tryptophan Hydroxylase in Lymphocytes of Rats: Mitogen Activation, Physical Restraint or Treatment with Reserpine
Mary Urbina et al.
NEUROIMMUNOMODULATION (2014)
Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits
Guomei Tang et al.
NEURON (2014)
Bidirectional Modulation of Incubation of Cocaine Craving by Silent Synapse-Based Remodeling of Prefrontal Cortex to Accumbens Projections
Yao-Ying Ma et al.
NEURON (2014)
Serotonin induces depolarization in lateral amygdala neurons by activation of TRPC-like current and inhibition of GIRK current depending on 5-HT2C receptor
Ryo Yamamoto et al.
NEUROPHARMACOLOGY (2014)
Serotonin at the nexus of impulsivity and cue reactivity in cocaine addiction
Kathryn A. Cunningham et al.
NEUROPHARMACOLOGY (2014)
Expression of 5-HT2A receptors in prefrontal cortex pyramidal neurons projecting to nucleus accumbens. Potential relevance for atypical antipsychotic action
Giuseppe Mocci et al.
NEUROPHARMACOLOGY (2014)
Developmental Effects of Serotonin 1A Autoreceptors on Anxiety and Social Behavior
Zoe R. Donaldson et al.
NEUROPSYCHOPHARMACOLOGY (2014)
Functional Status of the Serotonin 5-HT2C Receptor (5-HT2CR) Drives Interlocked Phenotypes that Precipitate Relapse-Like Behaviors in Cocaine Dependence
Noelle C. Anastasio et al.
NEUROPSYCHOPHARMACOLOGY (2014)
Rapid Anxiolytic Effects of a 5-HT4 Receptor Agonist Are Mediated by a Neurogenesis-Independent Mechanism
Indira Mendez-David et al.
NEUROPSYCHOPHARMACOLOGY (2014)
Clozapine Acts as an Agonist at Serotonin 2A Receptors to Counter MK-801-Induced Behaviors through a βArrestin2-Independent Activation of Akt
Cullen L. Schmid et al.
NEUROPSYCHOPHARMACOLOGY (2014)
Pharmacological Stimulation of the Brain Serotonin Receptor 7 as a Novel Therapeutic Approach for Rett Syndrome
Bianca De Filippis et al.
NEUROPSYCHOPHARMACOLOGY (2014)
SPINAL nNOS REGULATES PHRENIC MOTOR FACILITATION BY A 5-HT2B RECEPTOR- AND NADPH OXIDASE-DEPENDENT MECHANISM
P. M. Macfarlane et al.
NEUROSCIENCE (2014)
Alterations in the serotonin system in schizophrenia: A systematic review and meta-analysis of postmortem and molecular imaging studies
Sudhakar Selvaraj et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2014)
Controversies on the role of 5-HT2C receptors in the mechanisms of action of antidepressant drugs
Cedric B. P. Martin et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2014)
Direct Interaction and Functional Coupling between Human 5-HT6 Receptor and the Light Chain 1 Subunit of the Microtubule-Associated Protein 1B (MAP1B-LC1)
Soon-Hee Kim et al.
PLOS ONE (2014)
Regulation of Amyloid Precursor Protein Processing by Serotonin Signaling
Anna A. Pimenova et al.
PLOS ONE (2014)
Snx14 Regulates Neuronal Excitability, Promotes Synaptic Transmission, and Is Imprinted in the Brain of Mice
Hsien-Sung Huang et al.
PLOS ONE (2014)
The snoRNA MBII-52 Regulates Cocaine-Induced Conditioned Place Preference and Locomotion in Mice
Hongjie Chen et al.
PLOS ONE (2014)
A Dynamic View of Molecular Switch Behavior at Serotonin Receptors: Implications for Functional Selectivity
Maria Marti-Solano et al.
PLOS ONE (2014)
Serotonin 1A receptors and sexual behavior in male rats: A review
Eelke M. S. Snoeren et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2014)
Lorcaserin, a selective 5-HT2C receptor agonist, decreases alcohol intake in female alcohol preferring rats
Amir H. Rezvani et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2014)
Spinal 5-HT5A receptors mediate 5-HT-induced antinociception in several pain models in rats
Enriqueta Munoz-Islas et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2014)
The neural and genetic basis of executive function: Attention, cognitive flexibility, and response inhibition
Sheree F. Logue et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2014)
Serotonin 1A receptors and sexual behavior in female rats: A review
Eelke M. S. Snoeren et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2014)
Arrhythmias, elicited by catecholamines and serotonin, vanish in human chronic atrial fibrillation
Torsten Christ et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Design of donecopride, a dual serotonin subtype 4 receptor agonist/acetylcholinesterase inhibitor with potential interest for Alzheimer's disease treatment
Cedric Lecoutey et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Platelet 5-HT1A receptor correlates with major depressive disorder in drug-free patients
Zhang-Jin Zhang et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2014)
The effects of benzofury (5-APB) on the dopamine transporter and 5-HT2-dependent vasoconstriction in the rat
Patrick Dawson et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2014)
The involvement of serotonin polymorphisms in autistic spectrum symptomatology
Amaia Hervas et al.
PSYCHIATRIC GENETICS (2014)
Monoamine modulation of tonic GABAA inhibition
Vincenzo Crunelli et al.
REVIEWS IN THE NEUROSCIENCES (2014)
Selective agonists for serotonin 7 (5-HT7) receptor and their applications in preclinical models: an overview
Pantaleo Di Pilato et al.
REVIEWS IN THE NEUROSCIENCES (2014)
P5-HT1A receptors in mood and anxiety: recent insights into autoreceptor versus heteroreceptor function
Alvaro L. Garcia-Garcia et al.
PSYCHOPHARMACOLOGY (2014)
Effects of the 5-HT2C receptor agonist meta-chlorophenylpiperazine on appetite, food intake and emotional processing in healthy volunteers
J. M. Thomas et al.
PSYCHOPHARMACOLOGY (2014)
Interaction of psychoactive tryptamines with biogenic amine transporters and serotonin receptor subtypes
Bruce E. Blough et al.
PSYCHOPHARMACOLOGY (2014)
Serotonin-1A receptor stimulation mediates effects of a metabotropic glutamate 2/3 receptor antagonist, 2S-2-amino-2-(1S,2S-2-carboxycycloprop-1-yl)-3-(xanth-9-yl)propanoic acid (LY341495), and an N-methyl-D-aspartate receptor antagonist, ketamine, in the novelty-suppressed feeding test
Kenichi Fukumoto et al.
PSYCHOPHARMACOLOGY (2014)
An evaluation of the safety and efficacy of cariprazine in patients with acute exacerbation of schizophrenia: A phase II, randomized clinical trial
Suresh Durgam et al.
SCHIZOPHRENIA RESEARCH (2014)
Serotonin Enhances Megakaryopoiesis and Proplatelet Formation via p-Erk1/2 and F-Actin Reorganization
Jie Yu Ye et al.
STEM CELLS (2014)
The Prokaryote Ligand-Gated Ion Channel ELIC Captured in a Pore Blocker-Bound Conformation by the Alzheimer's Disease Drug Memantine
Chris Ulens et al.
STRUCTURE (2014)
5-HT7 receptors as modulators of neuronal excitability, synaptic transmission and plasticity: physiological role and possible implications in autism spectrum disorders
Lucia Ciranna et al.
FRONTIERS IN CELLULAR NEUROSCIENCE (2014)
Activity-dependent serotonergic excitation of callosal projection neurons in the mouse prefrontal cortex
Emily K. Stephens et al.
FRONTIERS IN NEURAL CIRCUITS (2014)
Antipsychotic Induced Weight Gain: Genetics, Epigenetics, and Biomarkers Reviewed
Tahireh A. Shams et al.
CURRENT PSYCHIATRY REPORTS (2014)
Emerging therapeutic options for acute migraine: focus on the potential of lasmiditan
Paul B. Rizzoli
NEUROPSYCHIATRIC DISEASE AND TREATMENT (2014)
Cellular mechanisms of the 5-HT7 receptor-mediated signaling
Daria Guseva et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2014)
Serotonin-prefrontal cortical circuitry in anxiety and depression phenotypes: pivotal role of pre- and post-synaptic 5-HT1A receptor expression
Paul R. Albert et al.
FRONTIERS IN BEHAVIORAL NEUROSCIENCE (2014)
Colonic Migrating Motor Complexes, High Amplitude Propagating Contractions, Neural Reflexes and the Importance of Neuronal and Mucosal Serotonin
Terence K. Smith et al.
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY (2014)
Variation within the serotonin (5-HT) 5-HT2C receptor system aligns with vulnerability to cocaine cue reactivity
N. C. Anastasio et al.
TRANSLATIONAL PSYCHIATRY (2014)
Pinpointing brainstenn mechanisms responsible for autonomic dysfunction in Rett syndrome: therapeutic perspectives for 5-HT1A agonists
Ana P. Abdala et al.
FRONTIERS IN PHYSIOLOGY (2014)
Role of SAP97 in the Regulation of 5-HT2AR Endocytosis and Signaling
Henry A. Dunn et al.
MOLECULAR PHARMACOLOGY (2014)
International Union of Basic and Clinical Pharmacology. XC. Multisite Pharmacology: Recommendations for the Nomenclature of Receptor Allosterism and Allosteric Ligands
Arthur Christopoulos et al.
PHARMACOLOGICAL REVIEWS (2014)
Agonism of the 5-Hydroxytryptamine 1F Receptor Promotes Mitochondrial Biogenesis and Recovery from Acute Kidney Injury
Sara M. Garrett et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2014)
From Hofmann to the Haight Ashbury, and into the Future: The Past and Potential of Lysergic Acid Diethlyamide
David E. Smith et al.
JOURNAL OF PSYCHOACTIVE DRUGS (2014)
Role of the N-Terminal Region in G Protein-Coupled Receptor Functions: Negative Modulation Revealed by 5-HT2B Receptor Polymorphisms
Arnauld Belmer et al.
MOLECULAR PHARMACOLOGY (2014)
Structure-Based Design of PDZ Ligands as Inhibitors of 5-HT2A Receptor/PSD-95 PDZ1 Domain Interaction Possessing Anti-hyperalgesic Activity
Alexandre Vogrig et al.
ACS CHEMICAL BIOLOGY (2013)
Activation of 5-HT6 Receptors Modulates Sleep-Wake Activity and Hippocampal Theta Oscillation
Susanna Ly et al.
ACS CHEMICAL NEUROSCIENCE (2013)
Extensive Rigid Analogue Design Maps the Binding Conformation of Potent N-Benzylphenethylamine 5-HT2A Serotonin Receptor Agonist Ligands
Jose I. Juncosa et al.
ACS CHEMICAL NEUROSCIENCE (2013)
5-HT4 Receptors Constitutively Promote the Non-Amyloidogenic Pathway of APP Cleavage and Interact with ADAM10
Maud Cochet et al.
ACS CHEMICAL NEUROSCIENCE (2013)
Synergism Between a Serotonin 5-HT2A Receptor (5-HT2AR) Antagonist and 5-HT2CR Agonist Suggests New Pharmacotherapeutics for Cocaine Addiction
Kathryn A. Cunningham et al.
ACS CHEMICAL NEUROSCIENCE (2013)
Partial Agonism of 5-HT3 Receptors: A Novel Approach to the Symptomatic Treatment of IBS-D
Nicholas A. Moore et al.
ACS CHEMICAL NEUROSCIENCE (2013)
A Dialogue between the Immune System and Brain, Spoken in the Language of Serotonin
Nicole L. Baganz et al.
ACS CHEMICAL NEUROSCIENCE (2013)
Array-Based Profiling of DNA Methylation Changes Associated with Alcohol Dependence
Huiping Zhang et al.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH (2013)
Serotonin contributes to high pulmonary vascular tone in a sheep model of persistent pulmonary hypertension of the newborn
Cassidy Delaney et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
NF-κB pathway is involved in CRP-induced effects on pulmonary arterial endothelial cells in chronic thromboembolic pulmonary hypertension
Marijke Wynants et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2013)
A novel regulator of angiogenesis in endothelial cells: 5-hydroxytriptamine 4 receptor
Jasmina Profirovic et al.
ANGIOGENESIS (2013)
Effects of the 5-HT4 receptor agonist, cisapride, on neuronally evoked responses in human bladder, urethra, and ileum
F. Aura Kullmann et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2013)
Role of 5-HT5A receptors in the consolidation of memory
Roberto Gonzalez et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
The effects of systemic and local microinjection into the central nervous system of the selective serotonin 5-HT6 receptor agonist WAY-208466 on sleep and wakefulness in the rat
Jaime M. Monti et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
Blonanserin reverses the phencyclidine (PCP)-induced impairment in novel object recognition (NOR) in rats: Role of indirect 5-HT1A partial agonism
M. Horiguchi et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
Amisulpride promotes cognitive flexibility in rats: The role of 5-HT7 receptors
Agnieszka Nikiforuk et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
The role of 5-HT7 receptor antagonism in the amelioration of MK-801-induced learning and memory deficits by the novel atypical antipsychotic drug lurasidone
Tomoko Horisawa et al.
BEHAVIOURAL BRAIN RESEARCH (2013)
Phencyclidine decreases tickling-induced 50-kHz ultrasound vocalizations in juvenile rats: a putative model of the negative symptoms of schizophrenia?
Denis Boulay et al.
BEHAVIOURAL PHARMACOLOGY (2013)
Structural insights into Cys-loop receptor function and ligand recognition
Mieke Nys et al.
BIOCHEMICAL PHARMACOLOGY (2013)
5-Hydroxytryptamine and Its Receptors in Systemic Vascular Walls
Takuji Machida et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2013)
Multiple Regulatory Variants Modulate Expression of 5-Hydroxytryptamine 2A Receptors in Human Cortex
Ryan M. Smith et al.
BIOLOGICAL PSYCHIATRY (2013)
Selective Serotonin Reuptake Inhibitors Inhibit Human Osteoclast and Osteoblast Formation and Function
Jason M. Hodge et al.
BIOLOGICAL PSYCHIATRY (2013)
Acidic biphenyl derivatives: Synthesis and biological activity of a new series of potent 5-HT4 receptor antagonists
Bjarne Brudeli et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2013)
Discovery of TD-8954, a clinical stage 5-HT4 receptor agonist with gastrointestinal prokinetic properties
R. Murray McKinnell et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
Synthesis and biological evaluation of positron emission tomography radiotracers targeting serotonin 4 receptors in brain: [18F]MNI-698 and [18F]MNI-699
Fabien Caille et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2013)
The 5-HT3AB Receptor Shows an A3B2 Stoichiometry at the Plasma Membrane
Timothy F. Miles et al.
BIOPHYSICAL JOURNAL (2013)
Platelet serotonin promotes the recruitment of neutrophils to sites of acute inflammation in mice
Daniel Duerschmied et al.
BLOOD (2013)
Degeneration of serotonergic neurons in amyotrophic lateral sclerosis: a link to spasticity
Christel Dentel et al.
BRAIN (2013)
Pharmacological profile of engineered 5-HT4 receptors and identification of 5-HT4 receptor-biased ligands
Florence Gaven et al.
BRAIN RESEARCH (2013)
Serotonergic innervation and serotonin receptor expression of NPY-producing neurons in the rat lateral and basolateral amygdaloid nuclei
M. Bonn et al.
BRAIN STRUCTURE & FUNCTION (2013)
Translational neuropharmacology: the use of human isolated gastrointestinal tissues
G. J. Sanger et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Discriminating between 5-HT3A and 5-HT3AB receptors
A. J. Thompson et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
5-Chloroindole: a potent allosteric modulator of the 5-HT3 receptor
Amy S. Newman et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
Cholinergic interactions between donepezil and prucalopride in human colon: potential to treat severe intestinal dysmotility
J. Broad et al.
BRITISH JOURNAL OF PHARMACOLOGY (2013)
An in Vivo Tagging Method Reveals that Ras Undergoes Sustained Activation upon Transglutaminase-Mediated Protein Serotonylation
Jason Ching-Yao Lin et al.
CHEMBIOCHEM (2013)
PET Radiotracers for Molecular Imaging of Serotonin 5-HT1A Receptors
T. Billard et al.
CURRENT MEDICINAL CHEMISTRY (2013)
Predictive In Silico Studies of Human 5-hydroxytryptamine Receptor Subtype 2B (5-HT2B) and Valvular Heart Disease
Terry-Elinor Reid et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2013)
Association of ABCB1 Polymorphisms with the Antiemetic Efficacy of Granisetron plus Dexamethasone in Breast Cancer Patients
Daiki Tsuji et al.
DRUG METABOLISM AND PHARMACOKINETICS (2013)
Structural basis of ligand recognition in 5-HT3 receptors
Divya Kesters et al.
EMBO REPORTS (2013)
Synthesis and pharmacological properties of a new hydrophilic and orally bioavailable 5-HT4 antagonist
Bjarne Brudeli et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2013)
The serotonin-2 receptor modulator, (-)-trans-PAT, decreases voluntary ethanol consumption in rats
James Kasper et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2013)
Neurochemical profiles of some novel psychoactive substances
Les Iversen et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2013)
Multiple roles of serotonin in pain control mechanisms -Implications of 5-HT7 and other 5-HT receptor types
Florent Viguier et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2013)
The relationship between gastric motility and nausea: Gastric prokinetic agents as treatments
Gareth J. Sanger et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2013)
Serotonin inhibits apoptosis of pulmonary artery smooth muscle cells through 5-HT2A receptors involved in the pulmonary artery remodeling of pulmonary artery hypertension
Ya Liu et al.
EXPERIMENTAL LUNG RESEARCH (2013)
Cariprazine, a new, orally active dopamine D2/3 receptor partial agonist for the treatment of schizophrenia, bipolar mania and depression
Tanja Veselinovic et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2013)
Association Between HTR1A Gene Polymorphisms and Attention Deficit Hyperactivity Disorder in Korean Children
Young Hyun Park et al.
GENETIC TESTING AND MOLECULAR BIOMARKERS (2013)
The enteric serotonergic system is altered in patients with diverticular disease
Martina Boettner et al.
GUT (2013)
The 5-HT4 Receptor Levels in Hippocampus Correlates Inversely With Memory Test Performance in Humans
Mette Ewers Haahr et al.
HUMAN BRAIN MAPPING (2013)
Overexpression of 5-Hydroxytryptamine 2B Receptor Gene in Pulmonary Hypertension: Still a Long Way to Understand its Transcriptional Regulation
Luc Maroteaux
HYPERTENSION (2013)
Serotonin2C ligands exhibiting full negative and positive intrinsic activity elicit purposeless oral movements in rats: distinct effects of agonists and inverse agonists in a rat model of Parkinson's disease
Sylvia Navailles et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2013)
Behavioural and neuroplastic properties of chronic lurasidone treatment in serotonin transporter knockout rats
Alessia Luoni et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2013)
Expression of α1-adrenergic receptors in rat prefrontal cortex: cellular co-localization with 5-HT2A receptors
Noemi Santana et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2013)
Augmentation of antipsychotic drug action by azapirone 5-HT1A receptor partial agonists: a meta-analysis
Taro Kishi et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2013)
5-HT1A-receptor agonist modified amygdala activity and amygdala-associated social behavior in a valproate-induced rat autism model
Chao-Chuan Wang et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2013)
A selective 5-HT1a receptor agonist improves respiration in a mouse model of Rett syndrome
Erica S. Levitt et al.
JOURNAL OF APPLIED PHYSIOLOGY (2013)
Lorcaserin and pimavanserin: emerging selectivity of serotonin receptor subtype-targeted drugs
Herbert Y. Meltzer et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Serotonin 2C receptors in pro-opiomelanocortin neurons regulate energy and glucose homeostasis
Eric D. Berglund et al.
JOURNAL OF CLINICAL INVESTIGATION (2013)
Polymorphisms of the HTR3B gene are associated with post-surgery emesis in a Chinese Han population
Xiao-Xu Ma et al.
JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS (2013)
Effects of Aripiprazole, Risperidone, and Olanzapine on 5-HT1A Receptors in Patients With Schizophrenia
Jerome Lerond et al.
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2013)
Effects on gastrointestinal functions and symptoms of serotonergic psychoactive agents used in functional gastrointestinal diseases
Madhusudan Grover et al.
JOURNAL OF GASTROENTEROLOGY (2013)
Targeted Inhibition of Serotonin Type 7 (5-HT7) Receptor Function Modulates Immune Responses and Reduces the Severity of Intestinal Inflammation
Janice J. Kim et al.
JOURNAL OF IMMUNOLOGY (2013)
Serotonin Skews Human Macrophage Polarization through HTR2B and HTR7
Mateo de las Casas-Engel et al.
JOURNAL OF IMMUNOLOGY (2013)
Neural Cell Adhesion Molecule-Mediated Fyn Activation Promotes GABAergic Synapse Maturation in Postnatal Mouse Cortex
Bidisha Chattopadhyaya et al.
JOURNAL OF NEUROSCIENCE (2013)
Short-Term Quetiapine Treatment Alters the Use of Reinforcement Signals during Risky Decision-Making and Promotes the Choice of Negative Expected Values in Healthy Adult Males
Philippa L. Rock et al.
JOURNAL OF NEUROSCIENCE (2013)
Peptide Inhibitors Disrupt the Serotonin 5-HT2C Receptor Interaction with Phosphatase and Tensin Homolog to Allosterically Modulate Cellular Signaling and Behavior
Noelle C. Anastasio et al.
JOURNAL OF NEUROSCIENCE (2013)
The 5-HT5A Receptor Regulates Excitability in the Auditory Startle Circuit: Functional Implications for Sensorimotor Gating
Paul C. P. Curtin et al.
JOURNAL OF NEUROSCIENCE (2013)
Metabolism of a Serotonin-4 Receptor Partial Agonist 4-{4-[4-Tetrahydrofuran-3-yloxy)-Benzo[d]Isoxazol-3-yloxymethyl]-Piperidin-1-ylmethyl}-Tetrahydropyran-4-ol (TBPT): Identification of an Unusual Pharmacologically Active Cyclized Oxazolidine Metabolite in Human
Aarti Sawant-Basak et al.
JOURNAL OF PHARMACEUTICAL SCIENCES (2013)
Flibanserin Treatment Increases Appetitive Sexual Motivation in the Female Rat
Helene Gelez et al.
JOURNAL OF SEXUAL MEDICINE (2013)
Efficacy of Flibanserin in Women with Hypoactive Sexual Desire Disorder: Results from the BEGONIA Trial
Molly Katz et al.
JOURNAL OF SEXUAL MEDICINE (2013)
5-HT2 Receptors Facilitate JC Polyomavirus Entry
Benedetta Assetta et al.
JOURNAL OF VIROLOGY (2013)
A Hybrid Structural Approach to Analyze Ligand Binding by the Serotonin Type 4 Receptor (5-HT4)
Pius S. Padayatti et al.
MOLECULAR & CELLULAR PROTEOMICS (2013)
Tyrosine Phosphorylation of the Rho Guanine Nucleotide Exchange Factor Trio Regulates Netrin-1/DCC-Mediated Cortical Axon Outgrowth
Jonathan DeGeer et al.
MOLECULAR AND CELLULAR BIOLOGY (2013)
Serotonin promotes the proliferation of serum-deprived hepatocellular carcinoma cells via upregulation of FOXO3a
Chao Liang et al.
MOLECULAR CANCER (2013)
RNA splicing and editing modulation of 5-HT2C receptor function: relevance to anxiety and aggression in VGV mice
C. B. P. Martin et al.
MOLECULAR PSYCHIATRY (2013)
Bidirectional regulation of emotional memory by 5-HT1B receptors involves hippocampal p11
T. M. Eriksson et al.
MOLECULAR PSYCHIATRY (2013)
OPINION Signalling bias in new drug discovery: detection, quantification and therapeutic impact
Terry Kenakin et al.
NATURE REVIEWS DRUG DISCOVERY (2013)
Serotonin signalling in the gut-functions, dysfunctions and therapeutic targets
Gary M. Mawe et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2013)
p11 and its role in depression and therapeutic responses to antidepressants
Per Svenningsson et al.
NATURE REVIEWS NEUROSCIENCE (2013)
Chronic 5-HT4 receptor activation decreases Ab production and deposition in hAPP/PS1 mice
Ina Tesseur et al.
NEUROBIOLOGY OF AGING (2013)
Targeting 5-HT1A receptors in astrocytes to protect dopaminergic neurons in parkinsonian models
Ikuko Miyazaki et al.
NEUROBIOLOGY OF DISEASE (2013)
Serotonin receptor of type 6 (5-HT6) in human prefrontal cortex and hippocampus post-mortem: An immunohistochemical and immunofluorescence study
Donatella Marazziti et al.
NEUROCHEMISTRY INTERNATIONAL (2013)
Postprandial symptoms originating from the stomach in functional dyspepsia
H. Vanheel et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2013)
5-HT radioligands for human brain imaging with PET and SPECT
Louise M. Paterson et al.
MEDICINAL RESEARCH REVIEWS (2013)
Support for 5-HT2C receptor functional selectivity in vivo utilizing structurally diverse, selective 5-HT2C receptor ligands and the 2,5-dimethoxy-4-iodoamphetamine elicited head-twitch response model
Clinton E. Canal et al.
NEUROPHARMACOLOGY (2013)
Rett syndrome treatment in mouse models: Searching for effective targets and strategies
Laura Ricceri et al.
NEUROPHARMACOLOGY (2013)
Evidence for a role of a dopamine/5-HT6 receptor interaction in cocaine reinforcement
V. Valentini et al.
NEUROPHARMACOLOGY (2013)
5-HT1A receptors direct the orientation of plasticity in layer 5 pyramidal neurons of the mouse prefrontal cortex
C. N. J. Meunier et al.
NEUROPHARMACOLOGY (2013)
Effects of lurasidone in behavioral models of depression. Role of the 5-HT7 receptor subtype
Lindsay N. Cates et al.
NEUROPHARMACOLOGY (2013)
The serotonin receptor 7 promotes neurite outgrowth via ERK and Cdk5 signaling pathways
L. Speranza et al.
NEUROPHARMACOLOGY (2013)
Cocaine Modulation of Frontostriatal Expression of Zif268, D2, and 5-HT2c Receptors in High and Low Impulsive Rats
Morgane Besson et al.
NEUROPSYCHOPHARMACOLOGY (2013)
Pyrvinium pamoate changes alternative splicing of the serotonin receptor 2C by influencing its RNA structure
Manli Shen et al.
NUCLEIC ACIDS RESEARCH (2013)
The effects of combining serotonin reuptake inhibition and 5-HT7 receptor blockade on circadian rhythm regulation in rodents
Ligia Westrich et al.
PHYSIOLOGY & BEHAVIOR (2013)
Transient, 5-HT2B receptor-mediated facilitation in neuropathic pain: Up-regulation of PKCγ and engagement of the NMDA receptor in dorsal horn neurons
Zigor Aira et al.
PAIN (2013)
Identification of a Novel Protein-Protein Interaction Motif Mediating Interaction of GPCR-Associated Sorting Proteins with G Protein-Coupled Receptors
Olivier Bornert et al.
PLOS ONE (2013)
Serotonin Receptor 2C and Insulin Secretion
Qiang Zhang et al.
PLOS ONE (2013)
Regulation of Serotonin-Induced Trafficking and Migration of Eosinophils
Bit Na Kang et al.
PLOS ONE (2013)
PDZ Domain-Mediated Interactions of G Protein-Coupled Receptors with Postsynaptic Density Protein 95: Quantitative Characterization of Interactions
Thor C. Moller et al.
PLOS ONE (2013)
Effects of the Selective 5-HT7 Receptor Antagonist SB-269970 and Amisulpride on Ketamine-Induced Schizophrenia-like Deficits in Rats
Agnieszka Nikiforuk et al.
PLOS ONE (2013)
Disruption of 5-HT2A Receptor-PDZ Protein Interactions Alleviates Mechanical Hypersensitivity in Carrageenan-Induced Inflammation in Rats
Anne-Sophie Wattiez et al.
PLOS ONE (2013)
Serotonin 2B Receptor (5-HT2B R) Signals through Prostacyclin and PPAR-β/δ in Osteoblasts
Yasmine Chabbi-Achengli et al.
PLOS ONE (2013)
Serotonin 1A, 1B, and 7 receptors of the rat medial nucleus accumbens differentially regulate feeding, water intake, and locomotor activity
Kara A. Clissold et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2013)
Inhibition and impulsivity: Behavioral and neural basis of response control
Andrea Bari et al.
PROGRESS IN NEUROBIOLOGY (2013)
HTR4 gene structure and altered expression in the developing lung
Emily Hodge et al.
RESPIRATORY RESEARCH (2013)
Persistent effects of chronic clozapine on the cellular and behavioral responses to LSD in mice
Jose L. Moreno et al.
PSYCHOPHARMACOLOGY (2013)
Ketamine elicits sustained antidepressant-like activity via a serotonin-dependent mechanism
Valentina Gigliucci et al.
PSYCHOPHARMACOLOGY (2013)
Aggression-reducing effects of F15599, a novel selective 5-HT1A receptor agonist, after microinjection into the ventral orbital prefrontal cortex, but not in infralimbic cortex in male mice
Dirson Joao Stein et al.
PSYCHOPHARMACOLOGY (2013)
Structural Basis for Molecular Recognition at Serotonin Receptors
Chong Wang et al.
SCIENCE (2013)
Structural Features for Functional Selectivity at Serotonin Receptors
Daniel Wacker et al.
SCIENCE (2013)
Serial Femtosecond Crystallography of G Protein-Coupled Receptors
Wei Liu et al.
SCIENCE (2013)
Gating of Pentameric Ligand-Gated Ion Channels: Structural Insights and Ambiguities
Corrie J. B. daCosta et al.
STRUCTURE (2013)
Indoleamine 2,3 dioxygenase and metabolic control of immune responses
David H. Munn et al.
TRENDS IN IMMUNOLOGY (2013)
Serotonin 2c receptor RNA editing in major depression and suicide
Rebecca Lyddon et al.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY (2013)
Agomelatine, a novel intriguing antidepressant option enhancing neuroplasticity: A critical review
Maurizio Pompili et al.
WORLD JOURNAL OF BIOLOGICAL PSYCHIATRY (2013)
Effects of 5-HT2B, 5-HT3 and 5-HT4 receptor antagonists on gastrointestinal motor activity in dogs
Hiroki Morita et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2013)
Predominant mucosal expression of 5-HT4(+h) receptor splice variants in pig stomach and colon
Evelien K. V. Priem et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2013)
5-Hydroxytryptamine (serotonin) in the gastrointestinal tract
Michael D. Gershon
CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY (2013)
Structural basis for potentiation by alcohols and anaesthetics in a ligand-gated ion channel
Ludovic Sauguet et al.
NATURE COMMUNICATIONS (2013)
A safe lithium mimetic for bipolar disorder
Nisha Singh et al.
NATURE COMMUNICATIONS (2013)
Tandospirone, a 5-HT1A partial agonist is effective in treating anorexia nervosa: a case series
Kyoji Okita et al.
ANNALS OF GENERAL PSYCHIATRY (2013)
High dose of 8-OH-DPAT decreases maximal dentate gyrus activation and facilitates granular cell plasticity in vivo
Gergely Orban et al.
EXPERIMENTAL BRAIN RESEARCH (2013)
Role of 5-HT2C receptors in the enhancement of c-Fos expression induced by a 5-HT2B/2C inverse agonist and 5-HT2 agonists in the rat basal ganglia
S. Navailles et al.
EXPERIMENTAL BRAIN RESEARCH (2013)
Functional anatomy of 5-HT2A receptors in the amygdala and hippocampal complex: relevance to memory functions
Cristiano Bombardi et al.
EXPERIMENTAL BRAIN RESEARCH (2013)
Functional significance of serotonin receptor dimerization
Katharine Herrick-Davis
EXPERIMENTAL BRAIN RESEARCH (2013)
The 5' untranslated region of the serotonin receptor 2C pre-mRNA generates miRNAs and is expressed in non-neuronal cells
Zhaiyi Zhang et al.
EXPERIMENTAL BRAIN RESEARCH (2013)
Decreased tryptophan metabolism in patients with autism spectrum disorders
Luigi Boccuto et al.
MOLECULAR AUTISM (2013)
BDNF overexpression in mouse hippocampal astrocytes promotes local neurogenesis and elicits anxiolytic-like activities
G. Quesseveur et al.
TRANSLATIONAL PSYCHIATRY (2013)
5-HT3 and 5-HT4 antagonists inhibit peristaltic contractions in guinea-pig distal colon by mechanisms independent of endogenous 5-HT
Tiong C. Sia et al.
FRONTIERS IN NEUROSCIENCE (2013)
Efficacy and safety of oral prucalopride in women with chronic constipation in whom laxatives have failed: an integrated analysis
Jan Tack et al.
UNITED EUROPEAN GASTROENTEROLOGY JOURNAL (2013)
Radiosynthesis and preclinical evaluation of [11C]prucalopride as a potential agonist PET ligand for the 5-HT4 receptor
Hans J. C. Buiter et al.
EJNMMI RESEARCH (2013)
Kinetics of 5-HT2B Receptor Signaling: Profound Agonist-Dependent Effects on Signaling Onset and Duration
David J. Unett et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2013)
Serotonin contracts the rat mesenteric artery by inhibiting 4-aminopyridine-sensitive Kv channels via the 5-HT2A receptor and Src tyrosine kinase
Dong Jun Sung et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2013)
The arylpiperazine derivatives N-(4-cyanophenylmethyl)4-( 2-diphenyl)-1-piperazinehexanamide and N-benzyl-4( 2-diphenyl)-1-piperazinehexanamide exert a long-lasting inhibition of human serotonin 5-HT7 receptor binding and cAMP signaling
Patricio Atanes et al.
PHARMACOLOGY RESEARCH & PERSPECTIVES (2013)
Fluorescence Correlation Spectroscopy Analysis of Serotonin, Adrenergic, Muscarinic, and Dopamine Receptor Dimerization: The Oligomer Number Puzzle
Katharine Herrick-Davis et al.
MOLECULAR PHARMACOLOGY (2013)
Exploration of Synthetic Approaches and Pharmacological Evaluation of PNU-69176E and Its Stereoisomer as 5-HT2C Receptor Allosteric Modulators
Chunyong Ding et al.
ACS CHEMICAL NEUROSCIENCE (2012)
Increased intra-individual reaction time variability in cocaine-dependent subjects: Role of cocaine-related cues
Shijing Liu et al.
ADDICTIVE BEHAVIORS (2012)
Systematic review: cardiovascular safety profile of 5-HT4 agonists developed for gastrointestinal disorders
J. Tack et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2012)
Comparison of effects of a selective 5-HT reuptake inhibitor versus a 5-HT4 receptor agonist on in vivo neurogenesis at the rectal anastomosis in rats
Isao Kawahara et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2012)
Serotonylated fibronectin is elevated in pulmonary hypertension
Lin Wei et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2012)
Selective blockade of 5-HT7 receptors facilitates attentional set-shifting in stressed and control rats
Agnieszka Nikiforuk
BEHAVIOURAL BRAIN RESEARCH (2012)
Effect of 5-HT5A antagonists in animal models of schizophrenia, anxiety and depression
Ferenc Kassai et al.
BEHAVIOURAL PHARMACOLOGY (2012)
Post-Translational Modifications of the Serotonin Type 4 Receptor Heterologously Expressed in Mouse Rod Cells
David Salom et al.
BIOCHEMISTRY (2012)
Mast cell-nerve axis with a focus on the human gut
Sabine Buhner et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE (2012)
Activation of 5-HT7 Serotonin Receptors Reverses Metabotropic Glutamate Receptor-Mediated Synaptic Plasticity in Wild-Type and Fmr1 Knockout Mice, a Model of Fragile X Syndrome
Lara Costa et al.
BIOLOGICAL PSYCHIATRY (2012)
Discovery, oral pharmacokinetics and in vivo efficacy of a highly selective 5-HT4 receptor agonist: Clinical compound TD-2749
Daniel D. Long et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2012)
Serotonin 5-HT2B receptors are required for bone-marrow contribution to pulmonary arterial hypertension
Jean-Marie Launay et al.
BLOOD (2012)
An integrative computational systems biology approach identifies differentially regulated dynamic transcriptome signatures which drive the initiation of human T helper cell differentiation
Tarmo Aijo et al.
BMC GENOMICS (2012)
SB 206553, a putative 5-HT2C inverse agonist, attenuates methamphetamine-seeking in rats
Steven M. Graves et al.
BMC NEUROSCIENCE (2012)
Activation of serotonin receptors promotes microglial injury-induced motility but attenuates phagocytic activity
Grietje Krabbe et al.
BRAIN BEHAVIOR AND IMMUNITY (2012)
Identification of alternatively spliced multiple transcripts of 5-hydroxytryptamine receptor in mouse
Shafquat Azim et al.
BRAIN RESEARCH BULLETIN (2012)
Imaging brain signal transduction and metabolism via arachidonic and docosahexaenoic acid in animals and humans
Mireille Basselin et al.
BRAIN RESEARCH BULLETIN (2012)
Preclinical and clinical characterization of the selective 5-HT1A receptor antagonist DU-125530 for antidepressant treatment
M. C. Scorza et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Distribution of 5-ht1E receptors in the mammalian brain and cerebral vasculature: an immunohistochemical and pharmacological study
M. T. Klein et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
The 5-HT3B subunit affects high-potency inhibition of 5-HT3 receptors by morphine
Daniel T. Baptista-Hon et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
5-HT6 receptor agonists and antagonists enhance learning and memory in a conditioned emotion response paradigm by modulation of cholinergic and glutamatergic mechanisms
S. Woods et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Regional- and agonist-dependent facilitation of human neurogastrointestinal functions by motilin receptor agonists
J. Broad et al.
BRITISH JOURNAL OF PHARMACOLOGY (2012)
Fluoxetine inhibits monocrotaline-induced pulmonary arterial remodeling involved in inhibition of RhoA-Rho kinase and Akt signalling pathways in rats
Han-Ming Wang et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2012)
Gut-Derived Serotonin Is a Multifunctional Determinant to Fasting Adaptation
Grzegorz Sumara et al.
CELL METABOLISM (2012)
μ-opioid and 5-HT1A receptors heterodimerize and show signalling crosstalk via G protein and MAP-kinase pathways
Didier Cussac et al.
CELLULAR SIGNALLING (2012)
RhoBTB3 interacts with the 5-HT7a receptor and inhibits its proteasomal degradation
Anne Matthys et al.
CELLULAR SIGNALLING (2012)
Expression of Serotonin Receptors in Human Hepatocellular Cancer
Christopher Soll et al.
CLINICAL CANCER RESEARCH (2012)
5-HT Receptor-Associated Protein Networks: New Targets for Drug Discovery in Psychiatric Disorders?
Philippe Marin et al.
CURRENT DRUG TARGETS (2012)
Fluorescent Probes: From Bench to Bedside
Enza Lacivita et al.
CURRENT MEDICINAL CHEMISTRY (2012)
Management of highly emetogenic chemotherapy
David Warr
CURRENT OPINION IN ONCOLOGY (2012)
Low Densities of Serotonin and Peptide YY Cells in the Colon of Patients with Irritable Bowel Syndrome
M. El-Salhy et al.
DIGESTIVE DISEASES AND SCIENCES (2012)
5-HT6 receptor recruitment of mTOR as a mechanism for perturbed cognition in schizophrenia
Julie Meffre et al.
EMBO MOLECULAR MEDICINE (2012)
Depression and epilepsy: Epidemiologic and neurobiologic perspectives that may explain their high comorbid occurrence
Andres M. Kanner et al.
EPILEPSY & BEHAVIOR (2012)
Serotonin2C receptors in the nucleus accumbens are involved in enhanced alcohol-drinking behavior
Kanji Yoshimoto et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2012)
Role of peripheral versus spinal 5-HT7 receptors in the modulation of pain undersensitizing conditions
A. Brenchat et al.
EUROPEAN JOURNAL OF PAIN (2012)
Vasoconstrictor 5-HT receptors in the smooth muscle of the rat middle cerebral artery
Aniko Kovacs et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Involvement of 5-HT7 receptors in the pathogenesis of temporal lobe epilepsy
Zhiyong Yang et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2012)
Biochemical and pharmacological study of N-linked glycosylation of the human serotonin 5-HT7(a) receptor
Evelien Gellynck et al.
FEBS JOURNAL (2012)
Transglutaminase-mediated transamidation of serotonin, dopamine and noradrenaline to fibronectin: Evidence for a general mechanism of monoaminylation
Rene Hummerich et al.
FEBS LETTERS (2012)
Mitral bioprosthesis hypertrophic scaring and native aortic valve fibrosis during benfluorex therapy
Estelle Ayme-Dietrich et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2012)
Neuronal Serotonin Regulates Growth of the Intestinal Mucosa in Mice
Erica R. Gross et al.
GASTROENTEROLOGY (2012)
Activation of Colonic Mucosal 5-HT4 Receptors Accelerates Propulsive Motility and Inhibits Visceral Hypersensitivity
Jill M. Hoffman et al.
GASTROENTEROLOGY (2012)
Peroxisome Proliferator-Activated Receptor-γ Ameliorates Pulmonary Arterial Hypertension by Inhibiting 5-Hydroxytryptamine 2B Receptor
Yahan Liu et al.
HYPERTENSION (2012)
Modulation of neuroplasticity pathways and antidepressant-like behavioural responses following the short-term (3 and 7 days) administration of the 5-HT4 receptor agonist RS67333
Jesus Pascual-Brazo et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2012)
A double-blind, randomized, placebo-controlled, active reference study of Lu AA21004 in patients with major depressive disorder
Enric Alvarez et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2012)
5-Hydroxytryptamine 5HT2C Receptors Form a Protein Complex with N-Methyl-D-aspartate GluN2A Subunits and Activate Phosphorylation of Src Protein to Modulate Motoneuronal Depolarization
Gregory E. Bigford et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Oligomer Size of the Serotonin 5-Hydroxytryptamine 2C (5-HT2C) Receptor Revealed by Fluorescence Correlation Spectroscopy with Photon Counting Histogram Analysis EVIDENCE FOR HOMODIMERS WITHOUT MONOMERS OR TETRAMERS
Katharine Herrick-Davis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Heterodimerization of serotonin receptors 5-HT1A and 5-HT7 differentially regulates receptor signalling and trafficking
Ute Renner et al.
JOURNAL OF CELL SCIENCE (2012)
Tryptophan hydroxylase-1 regulates immune tolerance and inflammation
Elizabeth C. Nowak et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2012)
Design, Synthesis, and Structure-Activity Relationships of Highly Potent 5-HT3 Receptor Ligands
Mark H. P. Verheij et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Discovery and Pharmacological Profile of New 1H-Indazole-3-carboxamide and 2H-Pyrrolo[3,4-c]quinoline Derivatives as Selective Serotonin 4 Receptor Ligands
Guido Furlotti et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Synthesis and Structure-Affinity Relationships of Selective High-Affinity 5-HT4 Receptor Antagonists: Application to the Design of New Potential Single Photon Emission Computed Tomography Tracers
Emmanuelle Dubost et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
Identification of Multiple 5-HT4 Partial Agonist Clinical Candidates for the Treatment of Alzheimer's Disease
Michael A. Brodney et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
5-HT2B antagonism arrests non-canonical TGF-β1-induced valvular myofibroblast differentiation
Joshua D. Hutcheson et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)
Serotonin 5-HT2A receptor-mediated hypertrophy is negatively regulated by caveolin-3 in cardiomyoblasts and neonatal cardiomyocytes
Jeanne Mialet-Perez et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2012)
5-Hydroxytryptamine 2C receptors tonically augment synaptic currents in the nucleus tractus solitarii
James R. Austgen et al.
JOURNAL OF NEUROPHYSIOLOGY (2012)
The Native Serotonin 5-HT5A Receptor: Electrophysiological Characterization in Rodent Cortex and 5-HT1A-Mediated Compensatory Plasticity in the Knock-Out Mouse
Nathalie M. Goodfellow et al.
JOURNAL OF NEUROSCIENCE (2012)
A New Vesicular Scaffolding Complex Mediates the G-Protein-Coupled 5-HT1A Receptor Targeting to Neuronal Dendrites
Sana Al Awabdh et al.
JOURNAL OF NEUROSCIENCE (2012)
5-HT7R/G12 Signaling Regulates Neuronal Morphology and Function in an Age-Dependent Manner
Fritz Kobe et al.
JOURNAL OF NEUROSCIENCE (2012)
Radiosynthesis and Preclinical Evaluation of 18F-F13714 as a Fluorinated 5-HT1A Receptor Agonist Radioligand for PET Neuroimaging
Laetitia Lemoine et al.
JOURNAL OF NUCLEAR MEDICINE (2012)
Radiosynthesis and Characterization of 11C-GSK215083 as a PET Radioligand for the 5-HT6 Receptor
Christine A. Parker et al.
JOURNAL OF NUCLEAR MEDICINE (2012)
Proteomics Strategy to Identify Substrates of LNX, a PDZ Domain-containing E3 Ubiquitin Ligase
Zhengguang Guo et al.
JOURNAL OF PROTEOME RESEARCH (2012)
Flibanserin and 8-OH-DPAT Implicate Serotonin in Association between Female Marmoset Monkey Sexual Behavior and Changes in Pair-Bond Quality
Yves Aubert et al.
JOURNAL OF SEXUAL MEDICINE (2012)
Open-Label Extension Study of Flibanserin in Women with Hypoactive Sexual Desire Disorder
Christopher Jayne et al.
JOURNAL OF SEXUAL MEDICINE (2012)
Treatment of Hypoactive Sexual Desire Disorder in Premenopausal Women: Efficacy of Flibanserin in the DAISY Study
John Thorp et al.
JOURNAL OF SEXUAL MEDICINE (2012)
On the presence of serotonin in mammalian cardiomyocytes
Klaus Poenicke et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2012)
Efficacy and tolerability of lasmiditan, an oral 5-HT1F receptor agonist, for the acute treatment of migraine: a phase 2 randomised, placebo-controlled, parallel-group, dose-ranging study
Markus Farkkila et al.
LANCET NEUROLOGY (2012)
5-HT2B receptors are required for serotonin-selective antidepressant actions
S. L. Diaz et al.
MOLECULAR PSYCHIATRY (2012)
Inotropic effects of prokinetic agents with 5-HT4 receptor agonist actions on human isolated myocardial trabeculae
Wenxia Chai et al.
LIFE SCIENCES (2012)
Activation of neuronal P2X7 receptor-pannexin-1 mediates death of enteric neurons during colitis
Brian D. Gulbransen et al.
NATURE MEDICINE (2012)
The migrating motor complex: control mechanisms and its role in health and disease
Eveline Deloose et al.
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY (2012)
Study of the regulation of the inotropic response to 5-HT4 receptor activation via phosphodiesterases and its cross-talk with C-type natriuretic peptide in porcine left atrium
S. Weninger et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2012)
Quantitative analysis of 5HT2C receptor RNA editing patterns in psychiatric disorders
Richard T. O'Neil et al.
NEUROBIOLOGY OF DISEASE (2012)
Assessment of serotonin release capacity in the human brain using dexfenfluramine challenge and [18F]altanserin positron emission tomography
Boris B. Quednow et al.
NEUROIMAGE (2012)
GABA, but not opioids, mediates the anti-hyperalgesic effects of 5-HT7 receptor activation in rats suffering from neuropathic pain
Florent Viguier et al.
NEUROPHARMACOLOGY (2012)
Modulatory effects of two novel agonists for serotonin receptor 7 on emotion, motivation and circadian rhythm profiles in mice
Walter Adriani et al.
NEUROPHARMACOLOGY (2012)
Effects of the 5-HT2C receptor agonist Ro60-0175 and the 5-HT2A receptor antagonist M100907 on nicotine self-administration and reinstatement
Paul J. Fletcher et al.
NEUROPHARMACOLOGY (2012)
The role of 5-HT1A receptors in fish oil-mediated increased BDNF expression in the rat hippocampus and cortex: A possible antidepressant mechanism
Aparecida Vines et al.
NEUROPHARMACOLOGY (2012)
The 5-HT2C Receptor Agonist Lorcaserin Reduces Nicotine Self-Administration, Discrimination, and Reinstatement: Relationship to Feeding Behavior and Impulse Control
Guy A. Higgins et al.
NEUROPSYCHOPHARMACOLOGY (2012)
Reduced Forebrain Serotonin Transmission is Causally Involved in the Development of Compulsive Cocaine Seeking in Rats
Yann Pelloux et al.
NEUROPSYCHOPHARMACOLOGY (2012)
5-HT1A and 5-HT7 receptors contribute to lurasidone-induced dopamine efflux
Mei Huang et al.
NEUROREPORT (2012)
DIFFERENTIAL DISTRIBUTION OF SEROTONIN RECEPTOR SUBTYPES IN BNSTALG NEURONS: MODULATION BY UNPREDICTABLE SHOCK STRESS
R. Hazra et al.
NEUROSCIENCE (2012)
Selective serotonin receptor stimulation of the medial nucleus accumbens differentially affects appetitive motivation for food on a progressive ratio schedule of reinforcement
Wayne E. Pratt et al.
NEUROSCIENCE LETTERS (2012)
Antinociceptive effect of peripheral serotonin 5-HT2B receptor activation on neuropathic pain
Nataliya Urtikova et al.
PAIN (2012)
Selective impairment of spinal mu-opioid receptor mechanism by plasticity of serotonergic facilitation mediated by 5-HT2A and 5-HT2B receptors
Zigor Aira et al.
PAIN (2012)
mRNA expression of 5-hydroxytryptamine 1B, 1D, and 1F receptors and their role in controlling the release of calcitonin gene-related peptide in the rat trigeminovascular system
Dipak V. Amrutkar et al.
PAIN (2012)
Identification of New Genes Involved in Human Adipogenesis and Fat Storage
Joern Soehle et al.
PLOS ONE (2012)
The Cardiac Ventricular 5-HT4 Receptor Is Functional in Late Foetal Development and Is Reactivated in Heart Failure
Trond Brattelid et al.
PLOS ONE (2012)
Quantitative Analysis of Focused A-To-I RNA Editing Sites by Ultra-High-Throughput Sequencing in Psychiatric Disorders
Hu Zhu et al.
PLOS ONE (2012)
Use of Buspirone and Fluoxetine for Breathing Problems in Rett Syndrome
Sarenur Gokben et al.
PEDIATRIC NEUROLOGY (2012)
A new approach for studying GPCR dimers: Drug-induced inactivation and reactivation to reveal GPCR dimer function in vitro, in primary culture, and in vivo
Milt Teitler et al.
PHARMACOLOGY & THERAPEUTICS (2012)
Role of peripheral and spinal 5-HT2B receptors in formalin-induced nociception
Claudia Cervantes-Duran et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2012)
5-HT7 receptor activation attenuates thermal hyperalgesia in streptozocin-induced diabetic mice
Ahmet Ulugol et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2012)
Serotonin receptor expression along the dorsal-ventral axis of mouse hippocampus
Kenji F. Tanaka et al.
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2012)
Transcriptional regulation of the 5-HT1A receptor: implications for mental illness
Paul R. Albert
PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES (2012)
Influence of the 5-HTR1A C-1019G polymorphism on clinical phenotypes of autism spectrum disorders
Jun Egawa et al.
PSYCHIATRY RESEARCH (2012)
In vivo electrophysiological and neurochemical effects of the selective 5-HT1A receptor agonist, F13640, at pre- and postsynaptic 5-HT1A receptors in the rat
Laia Llado-Pelfort et al.
PSYCHOPHARMACOLOGY (2012)
The role of 5-HT1A receptors in phencyclidine (PCP)-induced novel object recognition (NOR) deficit in rats
M. Horiguchi et al.
PSYCHOPHARMACOLOGY (2012)
A High-Coverage Genome Sequence from an Archaic Denisovan Individual
Matthias Meyer et al.
SCIENCE (2012)
Structure and Pharmacology of Pentameric Receptor Channels: From Bacteria to Brain
Pierre-Jean Corringer et al.
STRUCTURE (2012)
5-HT2A receptor blockade and 5-HT2C receptor activation interact to reduce cocaine hyperlocomotion and fos protein expression in the caudate-putamen
Lara A. Pockros et al.
SYNAPSE (2012)
Selective serotonergic excitation of callosal projection neurons
Daniel Avesar et al.
FRONTIERS IN NEURAL CIRCUITS (2012)
Dependencies among Editing Sites in Serotonin 2C Receptor mRNA
Liran Carmel et al.
PLOS COMPUTATIONAL BIOLOGY (2012)
Replication of functional serotonin receptor type 3A and B variants in bipolar affective disorder: a European multicenter study
C. Hammer et al.
TRANSLATIONAL PSYCHIATRY (2012)
Serotonin 1A receptor-mediated signaling through ERK and PKCα is essential for normal synaptogenesis in neonatal mouse hippocampus
A. Mogha et al.
TRANSLATIONAL PSYCHIATRY (2012)
The nucleus accumbens 5-HTR4-CART pathway ties anorexia to hyperactivity
A. Jean et al.
TRANSLATIONAL PSYCHIATRY (2012)
On the existence and function of galanin receptor heteromers in the central nervous system
Kjell Fuxe et al.
Frontiers in Endocrinology (2012)
Association between the HTR2B gene and the personality trait of fun seeking
Bi Zhu et al.
PERSONALITY AND INDIVIDUAL DIFFERENCES (2012)
The Serotonin 2C Receptor Antagonist SB 242084 Exhibits Abuse-Related Effects Typical of Stimulants in Squirrel Monkeys
Daniel F. Manvich et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
Translational Evaluation of JNJ-18038683, a 5-Hydroxytryptamine Type 7 Receptor Antagonist, on Rapid Eye Movement Sleep and in Major Depressive Disorder
Pascal Bonaventure et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
Effects of Serotonin 2C Receptor Agonists on the Behavioral and Neurochemical Effects of Cocaine in Squirrel Monkeys
Daniel F. Manvich et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
Serotonin and Blood Pressure Regulation
Stephanie W. Watts et al.
PHARMACOLOGICAL REVIEWS (2012)
Pharmacological Effects of Lu AA21004: A Novel Multimodal Compound for the Treatment of Major Depressive Disorder
A. Mork et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2012)
Risk factors for intestinal ischaemia among patients registered in a UK primary care database: a nested case-control study
C. Huerta et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2011)
Review article: the role of gastric motility in the control of food intake
P. Janssen et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2011)
Genome-Wide Association Study of Theta Band Event-Related Oscillations Identifies Serotonin Receptor Gene HTR7 Influencing Risk of Alcohol Dependence
Mark Zlojutro et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2011)
Serotonin Activates Dendritic Cell Function in the Context of Gut Inflammation
Nan Li et al.
AMERICAN JOURNAL OF PATHOLOGY (2011)
Activation of 5-hydroxytryptamine-1A receptors suppresses cardiovascular responses evoked from the paraventricular nucleus
Jouji Horiuchi et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2011)
Role of Protein Transamidation in Serotonin-Induced Proliferation and Migration of Pulmonary Artery Smooth Muscle Cells
Yinglin Liu et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2011)
Modulation of Striatal Projection Systems by Dopamine
Charles R. Gerfen et al.
ANNUAL REVIEW OF NEUROSCIENCE, VOL 34 (2011)
Serotonergic involvement in methamphetamine-induced locomotor activity: A detailed pharmacological study
Emily Steed et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
The effects of selective antagonists of serotonin 5-HT7 and 5-HT1A receptors on MK-801-induced impairment of learning and memory in the passive avoidance and Morris water maze tests in rats: Mechanistic implications for the beneficial effects of the novel atypical antipsychotic lurasidone
Tomoko Horisawa et al.
BEHAVIOURAL BRAIN RESEARCH (2011)
Impulsive behaviour in rats induced by intracortical DOI infusions is antagonized by co-administration of an mGlu2/3 receptor agonist
Lena Wischhof et al.
BEHAVIOURAL PHARMACOLOGY (2011)
5-HT2A receptor signalling through phospholipase D1 associated with its C-terminal tail
Zoe Barclay et al.
BIOCHEMICAL JOURNAL (2011)
Novel serotonin type 3 receptor partial agonists for the potential treatment of irritable bowel syndrome
David D. Manning et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Serotonin receptor 3A polymorphism c.-42C > T is associated with severe dyspepsia
Suhreta Mujakovic et al.
BMC MEDICAL GENETICS (2011)
Enhancement of reference memory in aged rats by specific activation of 5-HT4 receptors using an olfactory associative discrimination task
Evelyne Marchetti et al.
BRAIN RESEARCH (2011)
Characteristics of the actions by which 5-HT affects electrical and mechanical activities in rabbit jugular vein
Takeo Itoh et al.
BRITISH JOURNAL OF PHARMACOLOGY (2011)
The utility of rat models of impulsivity in developing pharmacotherapies for impulse control disorders
Catharine A. Winstanley
BRITISH JOURNAL OF PHARMACOLOGY (2011)
Allosteric modulation of the 5-HT3 receptor
Paul A. Davies
CURRENT OPINION IN PHARMACOLOGY (2011)
5-HT6 receptor and cognition
Xabier Codony et al.
CURRENT OPINION IN PHARMACOLOGY (2011)
5-HT3 receptors: potential of individual isoforms for personalised therapy
Beate Niesler
CURRENT OPINION IN PHARMACOLOGY (2011)
5-HT4 receptors, a place in the sun: act two
Joel Bockaert et al.
CURRENT OPINION IN PHARMACOLOGY (2011)
Targeting the 5-HT3 receptor in the treatment of irritable bowel syndrome
Robin C. Spiller
CURRENT OPINION IN PHARMACOLOGY (2011)
It might be a big family but the pain remains-last chance saloon for selective 5-HT receptor ligands?
Nick Andrews et al.
CURRENT OPINION IN PHARMACOLOGY (2011)
Communication between 5-HT and small GTPases
Charles P. Mercado et al.
CURRENT OPINION IN PHARMACOLOGY (2011)
The role of serotonin receptors in the action of atypical antipsychotic drugs
H. Y. Meltzer et al.
CURRENT OPINION IN PHARMACOLOGY (2011)
Convergence of the Insulin and Serotonin Programs in the Pancreatic β-Cell
Yasuharu Ohta et al.
DIABETES (2011)
Adipocytes express a functional system for serotonin synthesis, reuptake and receptor activation
A. K. Stunes et al.
DIABETES OBESITY & METABOLISM (2011)
The Risk of Ischaemic Colitis in Irritable Bowel Syndrome Patients Treated with Serotonergic Therapies
James H. Lewis
DRUG SAFETY (2011)
Increased expression of 5-HT6 receptors in dorsolateral striatum decreases habitual lever pressing, but does not affect learning acquisition of simple operant tasks in rats
Daniel Eskenazi et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2011)
ST1936 stimulates cAMP, Ca2+, ERK1/2 and Fyn kinase through a full activation of cloned human 5-HT6 receptors
Teresa Riccioni et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Drug discovery targeting human 5-HT2c receptors: Residues S3.36 and Y7.43 impact ligand Binding pocket structure via hydrogen bond formation
Clinton E. Canal et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
C-122, a novel antagonist of serotonin receptor 5-HT2B, prevents monocrotaline-induced pulmonary arterial hypertension in rats
David A. Zopf et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
The 5-HT1 receptors inhibiting the rat vasodepressor sensory CGRPergic outflow: Further involvement of 5-HT1F, but not 5-HT1A or 5-HT1D, subtypes
Abimael Gonzalez-Hernandez et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2011)
Terguride ameliorates monocrotaline-induced pulmonary hypertension in rats
R. Dumitrascu et al.
EUROPEAN RESPIRATORY JOURNAL (2011)
Novel roles for biogenic monoamines: from monoamines in transglutaminase-mediated post-translational protein modification to monoaminylation deregulation diseases
Diego J. Walther et al.
FEBS JOURNAL (2011)
The Tryptophan Hydroxylase Inhibitor LX1031 Shows Clinical Benefit in Patients With Nonconstipating Irritable Bowel Syndrome
Philip M. Brown et al.
GASTROENTEROLOGY (2011)
Altered ADAR 2 equilibrium and 5HT2CR editing in the prefrontal cortex of ADAR 2 transgenic mice
M. Singh et al.
GENES BRAIN AND BEHAVIOR (2011)
Increase of Capsaicin-Induced Trigeminal Fos-Like Immunoreactivity by 5-HT7 Receptors
Esther Martinez-Garcia et al.
HEADACHE (2011)
Activation of Serotonin Receptor-2B Rescues Small-for-Size Liver Graft Failure in Mice
Yinghua Tian et al.
HEPATOLOGY (2011)
Bioinformatic analyses to select phenotype affecting polymorphisms in HTR2C gene
Francesco Piva et al.
HUMAN PSYCHOPHARMACOLOGY-CLINICAL AND EXPERIMENTAL (2011)
Regulation of antigen-specific CTL and Th1 cell activation through 5-Hydroxytryptamine 2A receptor
Makoto Inoue et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2011)
5-HT1A Receptor Binding is Increased After Recovery from Bulimia Nervosa Compared to Control Women and is Associated with Behavioral Inhibition in Both Groups
Ursula F. Bailer et al.
INTERNATIONAL JOURNAL OF EATING DISORDERS (2011)
The melatonergic agonist and clinically active antidepressant, agomelatine, is a neutral antagonist at 5-HT2C receptors
Mark J. Millan et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2011)
Association of ABCB1, 5-HT3B Receptor and CYP2D6 Genetic Polymorphisms with Ondansetron and Metoclopramide Antiemetic Response in Indonesian Cancer Patients Treated with Highly Emetogenic Chemotherapy
Dyah A. Perwitasari et al.
JAPANESE JOURNAL OF CLINICAL ONCOLOGY (2011)
Cerebral Serotonin 4 Receptors and Amyloid-beta in Early Alzheimer's Disease
Karine Madsen et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Fyn, a Potential Target for Alzheimer's Disease
Kai Yang et al.
JOURNAL OF ALZHEIMERS DISEASE (2011)
Engineering a Prokaryotic Cys-loop Receptor with a Third Functional Domain
Raman Goyal et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Rings of Charge within the Extracellular Vestibule Influence Ion Permeation of the 5-HT3A Receptor
Matthew R. Livesey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Regulation of dorsal raphe nucleus function by serotonin autoreceptors: A behavioral perspective
Ross A. McDevitt et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2011)
Behind an enteric neuron there may lie a glial cell
Michael D. Gershon
JOURNAL OF CLINICAL INVESTIGATION (2011)
Glial cells in the mouse enteric nervous system can undergo neurogenesis in response to injury
Catia Laranjeira et al.
JOURNAL OF CLINICAL INVESTIGATION (2011)
Can We Really Accelerate and Enhance the Selective Serotonin Reuptake Inhibitor Antidepressant Effect? A Randomized Clinical Trial and a Meta-Analysis of Pindolol in Nonresistant Depression
Maria J. Portella et al.
JOURNAL OF CLINICAL PSYCHIATRY (2011)
Serotonin Receptor Diversity in the Human Colon: Expression of Serotonin Type 3 Receptor Subunits 5-HT3C, 5-HT3D, and 5-HT3E
Johannes Kapeller et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2011)
Interaction of the natural anxiolytic Galphimine-B with serotonergic drugs on dorsal hippocampus in rats
Enrique Jimenez-Ferrer et al.
JOURNAL OF ETHNOPHARMACOLOGY (2011)
Platelet-derived serotonin links vascular disease and tissue fibrosis
Clara Dees et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2011)
5-HT3 receptor ion size selectivity is a property of the transmembrane channel, not the cytoplasmic vestibule portals
Nicole K. McKinnon et al.
JOURNAL OF GENERAL PHYSIOLOGY (2011)
Continuous drug delivery in early- and late-stage Parkinson's disease as a strategy for avoiding dyskinesia induction and expression
P. Jenner et al.
JOURNAL OF NEURAL TRANSMISSION (2011)
Density and function of central serotonin (5-HT) transporters, 5-HT1A and 5-HT2A receptors, and effects of their targeting on BTBR T plus tf/J mouse social behavior
Georgianna G. Gould et al.
JOURNAL OF NEUROCHEMISTRY (2011)
The identification of N-glycosylated residues of the human 5-HT3B receptor subunit: importance for cell membrane expression
Andrew N. Massoura et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Motoneuron Excitability and Muscle Spasms Are Regulated by 5-HT2B and 5-HT2C Receptor Activity
Katherine C. Murray et al.
JOURNAL OF NEUROPHYSIOLOGY (2011)
Essential Role for Phosphatidylinositol 4,5-Bisphosphate in the Expression, Regulation, and Gating of the Slow Afterhyperpolarization Current in the Cerebral Cortex
Claudio Villalobos et al.
JOURNAL OF NEUROSCIENCE (2011)
Serotonin-1A Autoreceptors Are Necessary and Sufficient for the Normal Formation of Circuits Underlying Innate Anxiety
Jesse W. Richardson-Jones et al.
JOURNAL OF NEUROSCIENCE (2011)
Serotonin Receptor 5-HT2B Mediates Serotonin-Induced Mechanical Hyperalgesia
Shih-Yuan Lin et al.
JOURNAL OF NEUROSCIENCE (2011)
The Suppressive Effect of an Intra-Prefrontal Cortical Infusion of BDNF on Cocaine-Seeking Is Trk Receptor and Extracellular Signal-Regulated Protein Kinase Mitogen-Activated Protein Kinase Dependent
Timothy W. Whitfield et al.
JOURNAL OF NEUROSCIENCE (2011)
Essential Roles of Enteric Neuronal Serotonin in Gastrointestinal Motility and the Development/Survival of Enteric Dopaminergic Neurons
Zhishan Li et al.
JOURNAL OF NEUROSCIENCE (2011)
Potentiation of Morphine Analgesia by Adjuvant Activation of 5-HT7 Receptors
Alex Brenchat et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2011)
Toward Selective Drug Development for the Human 5-Hydroxytryptamine 1E Receptor: A Comparison of 5-Hydroxytryptamine 1E and 1F Receptor Structure-Affinity Relationships
Michael T. Klein et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Characterization of Vabicaserin (SCA-136), a Selective 5-Hydroxytryptamine 2C Receptor Agonist
John Dunlop et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Lorcaserin, a 5-HT2C Agonist, Decreases Nicotine Self-Administration in Female Rats
Edward D. Levin et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
The Role of 5-Hydroxytryptamine 7 Receptors in the Phencyclidine-Induced Novel Object Recognition Deficit in Rats
M. Horiguchi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Cysteine modification reveals which subunits form the ligand binding site in human heteromeric 5-HT3AB receptors
A. J. Thompson et al.
JOURNAL OF PHYSIOLOGY-LONDON (2011)
Increased expression of the 5-HT6 receptor by viral mediated gene transfer into posterior but not anterior dorsomedial striatum interferes with acquisition of a discrete action-outcome task
Daniel Eskenazi et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2011)
Multifunctional Pharmacology of Flibanserin: Possible Mechanism of Therapeutic Action in Hypoactive Sexual Desire Disorder
Stephen M. Stahl et al.
JOURNAL OF SEXUAL MEDICINE (2011)
Risperidone-Induced Inactivation and Clozapine-Induced Reactivation of Rat Cortical Astrocyte 5-Hydroxytryptamine7 Receptors: Evidence for In Situ G Protein-Coupled Receptor Homodimer Protomer Cross-Talk
Carol Smith et al.
MOLECULAR PHARMACOLOGY (2011)
Binding Sites for Bilobalide, Diltiazem, Ginkgolide, and Picrotoxinin at the 5-HT3 Receptor
A. J. Thompson et al.
MOLECULAR PHARMACOLOGY (2011)
Principles of activation and permeation in an anion-selective Cys-loop receptor
Ryan E. Hibbs et al.
NATURE (2011)
SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors
Paul Temkin et al.
NATURE CELL BIOLOGY (2011)
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
Maria Soler Artigas et al.
NATURE GENETICS (2011)
Stimulating healthy tissue regeneration by targeting the 5-HT2B receptor in chronic liver disease
Mohammad R. Ebrahimkhani et al.
NATURE MEDICINE (2011)
LX-1031, a tryptophan 5-hydroxylase inhibitor, and its potential in chronic diarrhea associated with increased serotonin
M. Camilleri
NEUROGASTROENTEROLOGY AND MOTILITY (2011)
Influence of the 5-HT3 receptor antagonist ondansetron on gastric sensorimotor function and nutrient tolerance in healthy volunteers
P. Janssen et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2011)
Functional Genomics of Serotonin Receptor 2A (HTR2A): Interaction of Polymorphism, Methylation, Expression and Disease Association
Virginia R. Falkenberg et al.
NEUROMOLECULAR MEDICINE (2011)
Serotonin 2C Receptor Activates a Distinct Population of Arcuate Pro-opiomelanocortin Neurons via TRPC Channels
Jong-Woo Sohn et al.
NEURON (2011)
Possible involvement of serotonin 5-HT2 receptor in the regulation of feeding behavior through the histaminergic system
Tomotaka Murotani et al.
NEUROPHARMACOLOGY (2011)
Activation of 5-HT6 receptors inhibits corticostriatal glutamatergic transmission
Annalisa Tassone et al.
NEUROPHARMACOLOGY (2011)
Co-expression of serotonin 5-HT1B and 5-HT4 receptors in p11 containing cells in cerebral cortex, hippocampus, caudate-putamen and cerebellum
Martin Egeland et al.
NEUROPHARMACOLOGY (2011)
Impulsive action induced by amphetamine, cocaine and MK801 is reduced by 5-HT2C receptor stimulation and 5-HT2A receptor blockade
Paul J. Fletcher et al.
NEUROPHARMACOLOGY (2011)
5-HT2C receptor regulation of defensive responses in the rat dorsal periaqueductal gray
Paula Shimene de Melo Yamashita et al.
NEUROPHARMACOLOGY (2011)
Increased serotonin axons (immunoreactive to 5-HT transporter) in postmortem brains from young autism donors
Efrain C. Azmitia et al.
NEUROPHARMACOLOGY (2011)
On the role of brain 5-HT7 receptor in the mechanism of hypothermia: Comparison with hypothermia mediated via 5-HT1A and 5-HT3 receptor
Vladimir S. Naumenko et al.
NEUROPHARMACOLOGY (2011)
Selective serotonin 5-HT2C receptor activation suppresses the reinforcing efficacy of cocaine and sucrose but differentially affects the incentive-salience value of cocaine- vs. sucrose-associated cues
Kathryn A. Cunningham et al.
NEUROPHARMACOLOGY (2011)
Implication of 5-HT2B receptors in the serotonin syndrome
Silvina Laura Diaz et al.
NEUROPHARMACOLOGY (2011)
Influence of social isolation in the rat on serotonergic function and memory - Relevance to models of schizophrenia and the role of 5-HT6 receptors
Charles A. Marsden et al.
NEUROPHARMACOLOGY (2011)
Deconstructing Antiobesity Compound Action: Requirement of Serotonin 5-HT2B Receptors for Dexfenfluramine Anorectic Effects
Sophie M. Banas et al.
NEUROPSYCHOPHARMACOLOGY (2011)
Pharmacological Blockade of 5-HT7 Receptors as a Putative Fast Acting Antidepressant Strategy
Ouissame Mnie-Filali et al.
NEUROPSYCHOPHARMACOLOGY (2011)
SEROTONIN 2A AND 2B RECEPTOR-INDUCED PHRENIC MOTOR FACILITATION: DIFFERENTIAL REQUIREMENT FOR SPINAL NADPH OXIDASE ACTIVITY
P. M. MacFarlane et al.
NEUROSCIENCE (2011)
5-HYDROXYTRYPTAMINE 2C RECEPTORS IN THE DORSAL STRIATUM MEDIATE STRESS-INDUCED INTERFERENCE WITH NEGATIVELY REINFORCED INSTRUMENTAL ESCAPE BEHAVIOR
P. V. Strong et al.
NEUROSCIENCE (2011)
5-HT2C Receptors Localize to Dopamine and GABA Neurons in the Rat Mesoaccumbens Pathway
Marcy J. Bubar et al.
PLOS ONE (2011)
Pharmacological Blockade of Serotonin 5-HT7 Receptor Reverses Working Memory Deficits in Rats by Normalizing Cortical Glutamate Neurotransmission
Pascal Bonaventure et al.
PLOS ONE (2011)
Serotonin-Mediated Tuning of Human Helper T Cell Responsiveness to the Chemokine CXCL12
Elena Magrini et al.
PLOS ONE (2011)
Expression and Function of Serotonin 2A and 2B Receptors in the Mammalian Respiratory Network
Marcus Niebert et al.
PLOS ONE (2011)
Serotonin Receptor Expression in Human Prefrontal Cortex: Balancing Excitation and Inhibition across Postnatal Development
Evelyn K. Lambe et al.
PLOS ONE (2011)
Serotonin Augments Gut Pacemaker Activity via 5-HT3 Receptors
Hong-Nian Liu et al.
PLOS ONE (2011)
Differences between human wild-type and C23S variant 5-HT2C receptors in inverse agonist-induced resensitization
Jutta Walstab et al.
PHARMACOLOGICAL REPORTS (2011)
Potential mechanisms of prospective antimigraine drugs: A focus on vascular (side) effects
Kayi Y. Chan et al.
PHARMACOLOGY & THERAPEUTICS (2011)
Therapeutics of 5-HT3 receptor antagonists: Current uses and future directions
Tina K. Machu
PHARMACOLOGY & THERAPEUTICS (2011)
Serotonin receptors and heart valve disease-It was meant 2B
Joshua D. Hutcheson et al.
PHARMACOLOGY & THERAPEUTICS (2011)
Blockade of 5-HT7 receptors reduces tactile allodynia in the rat
Evelyn Amaya-Castellanos et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2011)
Iloperidone, Asenapine, and Lurasidone: A Brief Overview of 3 New Second-Generation Antipsychotics
Leslie Citrome
POSTGRADUATE MEDICINE (2011)
Ineffective erythropoiesis with reduced red blood cell survival in serotonin-deficient mice
Pascal Amireault et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Serotonin reverts age-related capillarization and failure of regeneration in the liver through a VEGF-dependent pathway
Katarzyna Furrer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Discovery of β-Arrestin-Biased Dopamine D2 Ligands for Probing Signal Transduction Pathways Essential for Antipsychotic Efficacy
John A. Allen et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
E-6801, a 5-HT6 receptor agonist, improves recognition memory by combined modulation of cholinergic and glutamatergic neurotransmission in the rat
Ian Kendall et al.
PSYCHOPHARMACOLOGY (2011)
Blockade of nucleus accumbens 5-HT2A and 5-HT2C receptors prevents the expression of cocaine-induced behavioral and neurochemical sensitization in rats
Avi E. Zayara et al.
PSYCHOPHARMACOLOGY (2011)
Reversal of sibutramine-induced anorexia with a selective 5-HT2C receptor antagonist
Suzanne Higgs et al.
PSYCHOPHARMACOLOGY (2011)
Serotonin control of sleep-wake behavior
Jaime M. Monti
SLEEP MEDICINE REVIEWS (2011)
Therapeutic potential of β-arrestin- and G protein-biased agonists
Erin J. Whalen et al.
TRENDS IN MOLECULAR MEDICINE (2011)
The translational value of rodent gastrointestinal functions: a cautionary tale
Gareth J. Sanger et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2011)
Switching-on of serotonergic calcium signaling in activated hepatic stellate cells
Kyu-Sang Park et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2011)
Relationship between attentional bias to cocaine-related stimuli and impulsivity in cocaine-dependent subjects
Shijing Liu et al.
AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE (2011)
Excess of serotonin affects neocortical pyramidal neuron migration
O. Riccio et al.
TRANSLATIONAL PSYCHIATRY (2011)
Altered 5-HT2C receptor agonist-induced responses and 5-HT2C receptor RNA editing in the amygdala of serotonin transporter knockout mice
Pablo R Moya et al.
BMC Pharmacology & Toxicology (2011)
The hungry stomach: physiology, disease, and drug development opportunities
Gareth J. Sanger et al.
FRONTIERS IN PHARMACOLOGY (2011)
Sertindole in the Management of Schizophrenia
Mario F. Juruena et al.
JOURNAL OF CENTRAL NERVOUS SYSTEM DISEASE (2011)
Dual Therapy with Cidofovir and Mirtazapine for Progressive Multifocal Leukoencephalopathy in a Sarcoidosis Patient
Jae Hyun Parka et al.
CASE REPORTS IN NEUROLOGY (2011)
Antagonist Functional Selectivity: 5-HT2A Serotonin Receptor Antagonists Differentially Regulate 5-HT2A Receptor Protein Level In Vivo
Prem N. Yadav et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2011)
Metabolism and Pharmacokinetics of Naronapride (ATI-7505), a Serotonin 5-HT4 Receptor Agonist for Gastrointestinal Motility Disorders
S. Scott Bowersox et al.
DRUG METABOLISM AND DISPOSITION (2011)
Critical role of 5-HT1A, 5-HT3, and 5-HT7 receptor subtypes in the initiation, generation, and propagation of the murine colonic migrating motor complex
Eamonn J. Dickson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2010)
Cardiac overexpression of the human 5-HT4 receptor in mice
Ulrich Gergs et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2010)
Serotonin activates murine alveolar macrophages through 5-HT2C receptors
Zbigniew Mikulski et al.
AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY (2010)
Repinotan, a Selective 5-HT1A-R-Agonist, Antagonizes Morphine-Induced Ventilatory Depression in Anesthetized Rats
U. Guenther et al.
ANESTHESIA AND ANALGESIA (2010)
Spinal 5-HT7 Receptors Play an Important Role in the Antinociceptive and Antihyperalgesic Effects of Tramadol and Its Metabolite, O-Desmethyltramadol, via Activation of Descending Serotonergic Pathways
Omer Yanarates et al.
ANESTHESIOLOGY (2010)
GPCR Interacting Proteins (GIPs) in the Nervous System: Roles in Physiology and Pathologies
Joel Bockaert et al.
ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY (2010)
Serotonin release and uptake in the gastrointestinal tract
Paul P. Bertrand et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2010)
The 5-HT7 receptor as a mediator and modulator of antidepressant-like behavior
Gor Sarkisyan et al.
BEHAVIOURAL BRAIN RESEARCH (2010)
Behavioral and neurochemical effects of chronic L-DOPA treatment on nonmotor sequelae in the hemiparkinsonian rat
Karen L. Eskow Jaunarajs et al.
BEHAVIOURAL PHARMACOLOGY (2010)
Dopamine D2 and 5-hydroxytryptamine 5-HT2A receptors assemble into functionally interacting heteromers
Dasiel O. Borroto-Escuela et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2010)
Hetero-dimerization of serotonin 5-HT2A and dopamine D2 receptors
Sylwia Lukasiewicz et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2010)
Addiction: Decreased reward sensitivity and increased expectation sensitivity conspire to overwhelm the brain's control circuit
Nora D. Volkow et al.
BIOESSAYS (2010)
5-Hydroxytryptamine 2C Receptors in the Basolateral Amygdala Are Involved in the Expression of Anxiety After Uncontrollable Traumatic Stress
John P. Christianson et al.
BIOLOGICAL PSYCHIATRY (2010)
Synthesis and pharmacological properties of novel hydrophilic 5-HT4 receptor antagonists
Bjarne Brudeli et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2010)
Agonists and Antagonists Bind to an A-A Interface in the Heteromeric 5-HT3AB Receptor
M. Lochner et al.
BIOPHYSICAL JOURNAL (2010)
Dyskinesias after neural transplantation in Parkinson's disease: what do we know and what is next?
Marios Politis
BMC MEDICINE (2010)
Distribution of 5-HT1B, 5-HT1D and 5-HT1F receptor expression in rat trigeminal and dorsal root ganglia neurons: Relevance to the selective anti-migraine effect of triptans
J. D. Classey et al.
BRAIN RESEARCH (2010)
Mechanisms involved in the regulation of bovine pulmonary vascular tone by the 5-HT1B receptor
C. McKenzie et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Ligand-directed signalling at beta-adrenoceptors
Bronwyn A. Evans et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
Preferential in vivo action of F15599, a novel 5-HT1A receptor agonist, at postsynaptic 5-HT1A receptors
L. Llado-Pelfort et al.
BRITISH JOURNAL OF PHARMACOLOGY (2010)
The 5-HT2B Receptor Plays a Key Regulatory Role in Both Neuroendocrine Tumor Cell Proliferation and the Modulation of the Fibroblast Component of the Neoplastic Microenvironment
Bernhard Svejda et al.
CANCER (2010)
Serotonin 4 receptor (5-HT4R) internalization is isoform-specific: Effects of 5-HT and RS67333 on isoforms A and B
O. Mnie-Filali et al.
CELLULAR SIGNALLING (2010)
5-HT1A receptor-regulated signal transduction pathways in brain
Abigail M. Polter et al.
CELLULAR SIGNALLING (2010)
Preclinical pharmacological profile of the selective 5-HTIF receptor agonist lasmiditan
David L. Nelson et al.
CEPHALALGIA (2010)
Acute treatment of migraine with the selective 5-HTIF receptor agonist lasmiditan - A randomised proof-of-concept trial
Michel D. Ferrari et al.
CEPHALALGIA (2010)
Role of 5-HT2B receptors in cardiomyocyte apoptosis in noradrenaline-induced cardiomyopathy in rats
Chong-Feng Bai et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2010)
The role of dimerisation in the cellular trafficking of G-protein-coupled receptors
Graeme Milligan
CURRENT OPINION IN PHARMACOLOGY (2010)
Serotonin 2B receptor signaling is required for craniofacial morphogenesis and jaw joint formation in Xenopus
Elisa Reisoli et al.
DEVELOPMENT (2010)
Placental lactogens induce serotonin biosynthesis in a subset of mouse beta cells during pregnancy
A. Schraenen et al.
DIABETOLOGIA (2010)
Species Differences in the Formation of Vabicaserin Carbamoyl Glucuronide
Zeen Tong et al.
DRUG METABOLISM AND DISPOSITION (2010)
Social isolation stress induces ATF-7 phosphorylation and impairs silencing of the 5-HT 5B receptor gene
Toshio Maekawa et al.
EMBO JOURNAL (2010)
[18F]F15599, a novel 5-HT1A receptor agonist, as a radioligand for PET neuroimaging
Laetitia Lemoine et al.
EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING (2010)
F15599, a preferential post-synaptic 5-HT1A receptor agonist: Activity in models of cognition in comparison with reference 5-HT1A receptor agonists
Ronan Depoortere et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2010)
Evaluation of the effect of selective serotonin-reuptake inhibitors on lymphocyte subsets in patients with a major depressive disorder
Maria Eugenia Hernandez et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2010)
Controversies Involving the Role of 5-Hydroxytryptamine in Generating Colonic Migrating Motor Complexes: What Is Spontaneous?
Terence K. Smith et al.
GASTROENTEROLOGY (2010)
Serotonin Promotes Tumor Growth in Human Hepatocellular Cancer
Christopher Soll et al.
HEPATOLOGY (2010)
The snoRNA MBII-52 (SNORD 115) is processed into smaller RNAs and regulates alternative splicing
Shivendra Kishore et al.
HUMAN MOLECULAR GENETICS (2010)
Agonist-dependent modulation of G-protein coupling and transduction of 5-HT1A receptors in rat dorsal raphe nucleus
Elsa Maria Valdizan et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2010)
5-HT6 antagonism attenuates cue-induced relapse to cocaine seeking without affecting cocaine reinforcement
Marcel M. van Gaalen et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2010)
F15599, a highly selective post-synaptic 5-HT1A receptor agonist: in-vivo profile in behavioural models of antidepressant and serotonergic activity
Marie-Bernadette Assie et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2010)
Dopamine release induced by atypical antipsychotics in prefrontal cortex requires 5-HT1A receptors but not 5-HT2A receptors
Analia Bortolozzi et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2010)
Serotonergic 5-HT2B Receptor Controls Tissue-nonspecific Alkaline Phosphatase Activity in Osteoblasts via Eicosanoids and Phosphatidylinositol-specific Phospholipase C
Anne Baudry et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Physical Interaction of Jab1 with Human Serotonin 6 G-protein-coupled Receptor and Their Possible Roles in Cell Survival
Hyung-Mun Yun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Mechanism of interdigestive migrating motor complex in conscious dogs
Hitoshi Nakajima et al.
JOURNAL OF GASTROENTEROLOGY (2010)
Synthesis, Structure-Affinity Relationships, and Radiolabeling of Selective High-Affinity 5-HT4 Receptor Ligands as Prospective Imaging Probes for Positron Emission Tomography
Rong Xu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2010)
5-HT4 and 5-HT2 receptors antagonistically influence gap junctional coupling between rat auricular myocytes
Mickael Derangeon et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2010)
An Accurate, Clinically Feasible Multi-Gene Expression Assay for Predicting Metastasis in Uveal Melanoma
Michael D. Onken et al.
JOURNAL OF MOLECULAR DIAGNOSTICS (2010)
The central serotonin2B receptor: a new pharmacological target to modulate the mesoaccumbens dopaminergic pathway activity
Agnes L. Auclair et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Serotonin 5-HT2C receptor protein expression is enriched in synaptosomal and post-synaptic compartments of rat cortex
Noelle C. Anastasio et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Differences in the C-terminus contribute to variations in trafficking between rat and human 5-HT2A receptor isoforms: identification of a primate-specific tripeptide ASK motif that confers GRK-2 and β arrestin-2 interactions
Aditi Bhattacharya et al.
JOURNAL OF NEUROCHEMISTRY (2010)
Global Gene Expression Analysis of Rodent Motor Neurons Following Spinal Cord Injury Associates Molecular Mechanisms With Development of Postinjury Spasticity
J. Wienecke et al.
JOURNAL OF NEUROPHYSIOLOGY (2010)
The Largest Group of Superficial Neocortical GABAergic Interneurons Expresses Ionotropic Serotonin Receptors
SooHyun Lee et al.
JOURNAL OF NEUROSCIENCE (2010)
Serotonin Modulates Fast-Spiking Interneuron and Synchronous Activity in the Rat Prefrontal Cortex through 5-HT1A and 5-HT2A Receptors
M. Victoria Puig et al.
JOURNAL OF NEUROSCIENCE (2010)
Leptin Excites Proopiomelanocortin Neurons via Activation of TRPC Channels
Jian Qiu et al.
JOURNAL OF NEUROSCIENCE (2010)
Enhanced Function of Prefrontal Serotonin 5-HT2 Receptors in a Rat Model of Psychiatric Vulnerability
Madhurima Benekareddy et al.
JOURNAL OF NEUROSCIENCE (2010)
Serotonin, But Not N-Methyltryptamines, Activates the Serotonin 2A Receptor Via a β-Arrestin2/Src/Akt Signaling Complex In Vivo
Cullen L. Schmid et al.
JOURNAL OF NEUROSCIENCE (2010)
PRX-08066, a Novel 5-Hydroxytryptamine Receptor 2B Antagonist, Reduces Monocrotaline-Induced Pulmonary Arterial Hypertension and Right Ventricular Hypertrophy in Rats
Stacy L. Porvasnik et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
Cariprazine (RGH-188), a Dopamine D3 Receptor-Preferring, D3/D2 Dopamine Receptor Antagonist-Partial Agonist Antipsychotic Candidate: In Vitro and Neurochemical Profile
Bela Kiss et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
G protein coupled receptors as allosteric proteins and the role of allosteric modulators
Terry Kenakin
JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION (2010)
Acute and Repeated Flibanserin Administration in Female Rats Modulates Monoamines Differentially Across Brain Areas: A Microdialysis Study
Kelly A. Allers et al.
JOURNAL OF SEXUAL MEDICINE (2010)
Antiangiogenic Effect of a Selective 5-HT4 Receptor Agonist
Takeshi Nishikawa et al.
JOURNAL OF SURGICAL RESEARCH (2010)
Role of N-Linked Glycosylation of the 5-HT2A Receptor in JC Virus Infection
Melissa S. Maginnis et al.
JOURNAL OF VIROLOGY (2010)
Constitutive Activity of Serotonin2C Receptors at G Protein-Independent Signaling: Modulation by RNA Editing and Antidepressants
Marilyne Labasque et al.
MOLECULAR PHARMACOLOGY (2010)
High-Throughput Multiplexed Transcript Analysis Yields Enhanced Resolution of 5-Hydroxytryptamine2C Receptor mRNA Editing Profiles
Michael V. Morabito et al.
MOLECULAR PHARMACOLOGY (2010)
Disrupting 5-HT2A Receptor/PDZ Protein Interactions Reduces Hyperalgesia and Enhances SSRI Efficacy in Neuropathic Pain
Xavier Pichon et al.
MOLECULAR THERAPY (2010)
A population-specific HTR2B stop codon predisposes to severe impulsivity
Laura Bevilacqua et al.
NATURE (2010)
Genome-wide association study identifies five loci associated with lung function
Emmanouela Repapi et al.
NATURE GENETICS (2010)
Meta-analyses of genome-wide association studies identify multiple loci associated with pulmonary function
Dana B. Hancock et al.
NATURE GENETICS (2010)
Serotonin regulates pancreatic beta cell mass during pregnancy
Hail Kim et al.
NATURE MEDICINE (2010)
Long-term depression in the CNS
Graham L. Collingridge et al.
NATURE REVIEWS NEUROSCIENCE (2010)
Abnormal neural oscillations and synchrony in schizophrenia
Peter J. Uhlhaas et al.
NATURE REVIEWS NEUROSCIENCE (2010)
Structural basis of open channel block in a prokaryotic pentameric ligand-gated ion channel
Ricarda J. C. Hilf et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2010)
Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi syndrome
Michael V. Morabito et al.
NEUROBIOLOGY OF DISEASE (2010)
Changes in 5-HT4 receptor and 5-HT transporter binding in olfactory bulbectomized and glucocorticoid receptor heterozygous mice
Cecilie L. Licht et al.
NEUROCHEMISTRY INTERNATIONAL (2010)
Involvement of 5-Hydroxytryptamine in Canine Intestinal Motility Patterns
H. I. Davidson et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2010)
5-HT2B receptors modulate visceral hypersensitivity in a stress-sensitive animal model of brain-gut axis dysfunction
S. M. O'Mahony et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2010)
A selective, high affinity 5-HT2B receptor antagonist inhibits visceral hypersensitivity in rats
K. Ohashi-Doi et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2010)
Lack of serotonin 5-HT2B receptor alters proliferation and network volume of interstitial cells of Cajal in vivo
V. S. Tharayil et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2010)
A 5-HT4-receptor activation-induced neural plasticity enhances in vivo reconstructs of enteric nerve circuit insult
H. Matsuyoshi et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2010)
Enhancement of intestinal inflammation in mice lacking interleukin 10 by deletion of the serotonin reuptake transporter
S. Haub et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2010)
5-HT1A Autoreceptor Levels Determine Vulnerability to Stress and Response to Antidepressants
Jesse W. Richardson-Jones et al.
NEURON (2010)
Serotonin 1A receptor gene is associated with Japanese methamphetamine-induced psychosis patients
Taro Kishi et al.
NEUROPHARMACOLOGY (2010)
Neurocircuitry of Addiction
George F. Koob et al.
NEUROPSYCHOPHARMACOLOGY (2010)
Stimulation of Medial Prefrontal Cortex Serotonin 2C (5-HT2C) Receptors Attenuates Cocaine-Seeking Behavior
Nathan S. Pentkowski et al.
NEUROPSYCHOPHARMACOLOGY (2010)
Increased cortical expression of an RNA editing enzyme occurs in major depressive suicide victims
Micah Simmons et al.
NEUROREPORT (2010)
THE ROLE OF PERIPHERAL 5-HT1A, 5-HT1B, 5-HT1D, 5-HT1E AND 5-HT1F SEROTONERGIC RECEPTORS IN THE REDUCTION OF NOCICEPTION IN RATS
V. Granados-Soto et al.
NEUROSCIENCE (2010)
SUBTYPE-SPECIFIC CHANGES IN 5-HT RECEPTOR-MEDIATED MODULATION OF C FIBRE-EVOKED SPINAL FIELD POTENTIALS ARE TRIGGERED BY PERIPHERAL NERVE INJURY
Z. Aira et al.
NEUROSCIENCE (2010)
Effects of the 5-HT4 receptor agonist RS67333 and paroxetine on hippocampal extracellular 5-HT levels
Cecilie Loee Licht et al.
NEUROSCIENCE LETTERS (2010)
Serotonin receptor 5-HT5A in rat hippocampus decrease by leptin treatment
Guadalupe Garcia-Alcocer et al.
NEUROSCIENCE LETTERS (2010)
LP-211 is a brain penetrant selective agonist for the serotonin 5-HT7 receptor
Peter B. Hedlund et al.
NEUROSCIENCE LETTERS (2010)
Assessing serotonin receptor mRNA editing frequency by a novel ultra high-throughput sequencing method
Atheir I. Abbas et al.
NUCLEIC ACIDS RESEARCH (2010)
Serotonin (5-HT) receptor 5A sequence variants affect human plasma triglyceride levels
Y. Zhang et al.
PHYSIOLOGICAL GENOMICS (2010)
Pharmacological activation of 5-HT7 receptors reduces nerve injury-induced mechanical and thermal hypersensitivity
Alex Brenchat et al.
PAIN (2010)
Seven Transmembrane Receptors as Shapeshifting Proteins: The Impact of Allosteric Modulation and Functional Selectivity on New Drug Discovery
Terry Kenakin et al.
PHARMACOLOGICAL REVIEWS (2010)
Contribution of gene-modified mice and rats to our understanding of the cardiovascular pharmacology of serotonin
Laurent Monassier et al.
PHARMACOLOGY & THERAPEUTICS (2010)
The relevance of preclinical research models for the development of antimigraine drugs: Focus on 5-HT1B/1D and CGRP receptors
Saurabh Gupta et al.
PHARMACOLOGY & THERAPEUTICS (2010)
5-HT3 receptors: Role in disease and target of drugs
Jutta Walstab et al.
PHARMACOLOGY & THERAPEUTICS (2010)
Behavioural satiety sequence (BSS) Separating wheat from chaff in the behavioural pharmacology of appetite
R. J. Rodgers et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2010)
Reversal of hippocampal neuronal maturation by serotonergic antidepressants
Katsunori Kobayashi et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
β-Blocker drugs mediate calcium signaling in native central nervous system neurons by β-arrestin-biased agonism
Anastassios V. Tzingounis et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Correction of respiratory disorders in a mouse model of Rett syndrome
Ana P. L. Abdala et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
RGS inhibition at Gαi2 selectively potentiates 5-HT1A-mediated antidepressant effects
Jeffery N. Talbot et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Activation of 5-HT6 receptors facilitates attentional set shifting
Katherine E. Burnham et al.
PSYCHOPHARMACOLOGY (2010)
Clozapine and other competitive antagonists reactivate risperidone-inactivated h5-HT7 receptors: radioligand binding and functional evidence for GPCR homodimer protomer interactions
Milt Teitler et al.
PSYCHOPHARMACOLOGY (2010)
The structural basis of function in Cys-loop receptors
Andrew J. Thompson et al.
QUARTERLY REVIEWS OF BIOPHYSICS (2010)
The roles of phospholipase C activation and alternative ADAR1 and ADAR2 pre-mRNA splicing in modulating serotonin 2C-receptor editing in vivo
Claudia Schmauss et al.
RNA (2010)
MiR-16 Targets the Serotonin Transporter: A New Facet for Adaptive Responses to Antidepressants
Anne Baudry et al.
SCIENCE (2010)
Increased expression of 5-hydroxytryptamine2A/B receptors in idiopathic pulmonary fibrosis: a rationale for therapeutic intervention
Melanie Koenigshoff et al.
THORAX (2010)
Htr2a gene and 5-HT2A receptor expression in the cerebral cortex studied using genetically modified mice
Elaine T. Weber et al.
FRONTIERS IN NEUROSCIENCE (2010)
Modifying 5-HT1A receptor gene expression as a new target for antidepressant therapy
Paul R. Albert et al.
FRONTIERS IN NEUROSCIENCE (2010)
G Protein - Mediated Signaling: Same Receptor, Multiple Effectors
Andrew Woehler et al.
Current Molecular Pharmacology (2010)
Flibanserin: a potential treatment for Hypoactive Sexual Desire Disorder in premenopausal women
A. H. Clayton et al.
WOMENS HEALTH (2010)
Pharmacological Profile of Lurasidone, a Novel Antipsychotic Agent with Potent 5-Hydroxytryptamine 7 (5-HT7) and 5-HT1A Receptor Activity
Tadashi Ishibashi et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2010)
The novel melatonergic antidepressant, agomelatine, is a neutral antagonist at constitutively-active serotonin2C receptors
M. Millan et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2010)
Efficacy of 5-HT3 Antagonists and 5-HT4 Agonists in Irritable Bowel Syndrome: Systematic Review and Meta-Analysis
Alexander C. Ford et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2009)
Role of serotonin in intestinal inflammation: knockout of serotonin reuptake transporter exacerbates 2,4,6-trinitrobenzene sulfonic acid colitis in mice
Stephan C. Bischoff et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2009)
The spleen is required for 5-HT1A receptor agonist-mediated increases in mean circulatory filling pressure during hemorrhagic shock in the rat
Ruslan Tiniakov et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)
Inhibition of the cardiovascular response to stress by systemic 5-HT1A activation: sympathoinhibition or anxiolysis?
Daniel M. L. Vianna et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2009)
RhoA and Rho Kinase Activation in Human Pulmonary Hypertension Role of 5-HT Signaling
Christophe Guilluy et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2009)
Do Variations in the 5-HT3A and 5-HT3B Serotonin Receptor Genes (HTR3A and HTR3B) Influence the Occurrence of Postoperative Vomiting?
Henrik Rueffert et al.
ANESTHESIA AND ANALGESIA (2009)
Wnt2 acts as an angiogenic growth factor for non-sinusoidal endothelial cells and inhibits expression of stanniocalcin-1
Diana Klein et al.
ANGIOGENESIS (2009)
Mirtazapine Use in Human Immunodeficiency Virus-Infected Patients With Progressive Multifocal Leukoencephalopathy
Deanna Cettomai et al.
ARCHIVES OF NEUROLOGY (2009)
Selective Serotonin Receptor Stimulation of the Medial Nucleus Accumbens Causes Differential Effects on Food Intake and Locomotion
Wayne E. Pratt et al.
BEHAVIORAL NEUROSCIENCE (2009)
The 5-HT7 receptor is involved in allocentric spatial memory information processing
Gor Sarkisyan et al.
BEHAVIOURAL BRAIN RESEARCH (2009)
Constitutive Gs-mediated, but not G12-mediated, activity of the 5-hydroxytryptamine 5-HT7(a) receptor is modulated by the palmitoylation of its C-terminal domain
Elena Kvachnina et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
S100B's double life: Intracellular regulator and extracellular signal
Rosario Donato et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2009)
The Serotonin-1A Receptor in Anxiety Disorders
Elena Akimova et al.
BIOLOGICAL PSYCHIATRY (2009)
Novel antagonists of serotonin-4 receptors: Synthesis and biological evaluation of pyrrolothienopyrazines
Stephane Lemaitre et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2009)
Differential mediation of descending pain facilitation and inhibition by spinal 5HT-3 and 5HT-7 receptors
Ahmet Dogrul et al.
BRAIN RESEARCH (2009)
Signal transduction and functional selectivity of F15599, a preferential post-synaptic 5-HT1A receptor agonist
A. Newman-Tancredi et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Inhibition of colonic motility and defecation by RS-127445 suggests an involvement of the 5-HT2B receptor in rodent large bowel physiology
A. K. Bassil et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
Phospholipase A2 Biochemistry
John E. Burke et al.
CARDIOVASCULAR DRUGS AND THERAPY (2009)
A Serotonin-Dependent Mechanism Explains the Leptin Regulation of Bone Mass, Appetite, and Energy Expenditure
Vijay K. Yadav et al.
CELL (2009)
Amyloid beta-derived neuroplasticity in bone marrow-derived mesenchymal stem cells is mediated by NPY and 5-HT2B receptors via ERK1/2 signalling pathways
H. K. Jin et al.
CELL PROLIFERATION (2009)
Pyramidal Neurons in Rat Prefrontal Cortex Projecting to Ventral Tegmental Area and Dorsal Raphe Nucleus Express 5-HT2A Receptors
Pablo Vazquez-Borsetti et al.
CEREBRAL CORTEX (2009)
Serotonin and Angiotensin Receptors in Cardiac Fibroblasts Coregulate Adrenergic-Dependent Cardiac Hypertrophy
Fabrice Jaffre et al.
CIRCULATION RESEARCH (2009)
BODY DISTRIBUTION OF INFUSED SEROTONIN IN RATS
A. Elizabeth Linder et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2009)
Vilazodone: A 5-HT1A Receptor Agonist/Serotonin Transporter Inhibitor for the Treatment of Affective Disorders
Lee A. Dawson et al.
CNS NEUROSCIENCE & THERAPEUTICS (2009)
Serotonin Receptors, Type 4: A New Hope?
Guillaume Lucas
CURRENT DRUG TARGETS (2009)
The 5-HT1B Receptor: A Novel Target for the Pathophysiology of Depression
B. M. Ruf et al.
CURRENT DRUG TARGETS (2009)
Nicotinic acetylcholine receptors at atomic resolution
Victor Tsetlin et al.
CURRENT OPINION IN PHARMACOLOGY (2009)
β-arrestin1 phosphorylation by GRK5 regulates G protein-independent 5-HT4 receptor signalling
Gael Barthet et al.
EMBO JOURNAL (2009)
Effect of piboserod, a 5-HT4 serotonin receptor antagonist, on left ventricular function in patients with symptomatic heart failure
John K. Kjekshus et al.
EUROPEAN JOURNAL OF HEART FAILURE (2009)
Serotonin excites fast-spiking interneurons in the striatum
Craig P. Blomeley et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2009)
Role of monoamine oxidases in the exaggerated 5-hydroxytryptamine-induced tension development of human isolated preeclamptic umbilical artery
Sai Wang Seto et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
In vitro and in vivo pharmacological characterization of PF-01354082, a novel partial agonist selective for the 5-HT4 receptor
Tadayoshi Mikami et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
Spinal sumatriptan inhibits capsaicin-induced canine external carotid vasodilatation via 5-HT1B rather than 5-HT1D receptors
Enriqueta Munoz-Islas et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2009)
D1-like receptor activation improves PCP-induced cognitive deficits in animal models: Implications for mechanisms of improved cognitive function in schizophrenia
Samantha L. McLean et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2009)
Serotonin neuron-dependent and -independent reduction of dyskinesia by 5-HT1A and 5-HT1B receptor agonists in the rat Parkinson model
Ana Munoz et al.
EXPERIMENTAL NEUROLOGY (2009)
Serotonin Has a Key Role in Pathogenesis of Experimental Colitis
Jean-Eric Ghia et al.
GASTROENTEROLOGY (2009)
Loss of the imprinted snoRNA mbii-52 leads to increased 5htr2c pre-RNA editing and altered 5HT2CR-mediated behaviour
Christine M. Doe et al.
HUMAN MOLECULAR GENETICS (2009)
Fluoxetine treatment to rats modifies serotonin transporter and cAMP in lymphocytes, CD4+and CD8+subpopulations and interleukins 2 and 4
Fili Fazzino et al.
INTERNATIONAL IMMUNOPHARMACOLOGY (2009)
Role of serotonin 5-HT1A receptors in the antidepressant-like effect and the antinociceptive effect of venlafaxine in mice
Esther Berrocoso et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2009)
Ribosomal S6 Kinase 2 Directly Phosphorylates the 5-Hydroxytryptamine 2A (5-HT2A) Serotonin Receptor, Thereby Modulating 5-HT2A Signaling
Ryan T. Strachan et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Evaluation of the novel 5-HT4 receptor PET ligand [C-11]SB207145 in the Gottingen minipig
Birgitte R. Kornum et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2009)
Lurasidone in the Treatment of Acute Schizophrenia: A Double-Blind, Placebo-Controlled Trial
Mitsutaka Nakamura et al.
JOURNAL OF CLINICAL PSYCHIATRY (2009)
Phospholipase A2 structure/function, mechanism, and signaling
John E. Burke et al.
JOURNAL OF LIPID RESEARCH (2009)
A Multivalent Approach to the Design and Discovery of Orally Efficacious 5-HT4 Receptor Agonists
R. Murray McKinnell et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
Platelet derived serotonin drives the activation of rat cardiac fibroblasts by 5-HT2A receptors
Samiye Yabanoglu et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2009)
Characterisation of 5-HT3C, 5-HT3D and 5-HT3E receptor subunits: evolution, distribution and function
Joanna D. Holbrook et al.
JOURNAL OF NEUROCHEMISTRY (2009)
In vivo evidence that constitutive activity of serotonin2C receptors in the medial prefrontal cortex participates in the control of dopamine release in the rat nucleus accumbens: differential effects of inverse agonist versus antagonist
Gian Marco Leggio et al.
JOURNAL OF NEUROCHEMISTRY (2009)
Layer II/III of the Prefrontal Cortex: Inhibition by the Serotonin 5-HT1A Receptor in Development and Stress
Nathalie M. Goodfellow et al.
JOURNAL OF NEUROSCIENCE (2009)
PSD-95 Is Essential for Hallucinogen and Atypical Antipsychotic Drug Actions at Serotonin Receptors
Atheir I. Abbas et al.
JOURNAL OF NEUROSCIENCE (2009)
5-HT4 Receptor-Mediated Neuroprotection and Neurogenesis in the Enteric Nervous System of Adult Mice
Min-Tsai Liu et al.
JOURNAL OF NEUROSCIENCE (2009)
Role of p11 in Cellular and Behavioral Effects of 5-HT4 Receptor Stimulation
Jennifer L. Warner-Schmidt et al.
JOURNAL OF NEUROSCIENCE (2009)
An innovative real-time PCR method to measure changes in RNA editing of the serotonin 2C receptor (5-HT2CR) in brain
Maria Fe Lanfranco et al.
JOURNAL OF NEUROSCIENCE METHODS (2009)
Adaptations in 5-HT Receptor Expression and Function: Implications for Treatment of Cognitive Impairment in Aging
Ellen S. Mitchell et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2009)
Kinetic Modeling of 11C-SB207145 Binding to 5-HT4 Receptors in the Human Brain In Vivo
Lisbeth Marner et al.
JOURNAL OF NUCLEAR MEDICINE (2009)
Expression of mRNA for 5-HT2 Receptors and Proteins Related to Inactivation of 5-HT in Mouse Osteoblasts
Takao Hirai et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2009)
Asenapine: a novel psychopharmacologic agent with a unique human receptor signature
M. Shahid et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2009)
Direct Subunit-Dependent Multimodal 5-Hydroxytryptamine3 Receptor Antagonism by Methadone
Tarek Z. Deeb et al.
MOLECULAR PHARMACOLOGY (2009)
Parallel Functional Activity Profiling Reveals Valvulopathogens Are Potent 5-Hydroxytryptamine2B Receptor Agonists: Implications for Drug Safety Assessment
Xi-Ping Huang et al.
MOLECULAR PHARMACOLOGY (2009)
Excess of serotonin affects embryonic interneuron migration through activation of the serotonin receptor 6
O. Riccio et al.
MOLECULAR PSYCHIATRY (2009)
Enhanced tonic GABAA inhibition in typical absence epilepsy
David W. Cope et al.
NATURE MEDICINE (2009)
Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
P. Jeffrey Conn et al.
NATURE REVIEWS DRUG DISCOVERY (2009)
Fibrosis and carcinoid syndrome: from causation to future therapy
Maralyn Druce et al.
NATURE REVIEWS ENDOCRINOLOGY (2009)
Activation of G proteins and extracellular signal-regulated kinase 1/2 phosphorylation via human dopamine D-4.4 receptors: differential pathway-dependent potencies of receptor agonists
Peter Heusler et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2009)
Phosphorylation of phospholamban and troponin I through 5-HT4 receptors in the isolated human atrium
Ulrich Gergs et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2009)
A placebo-controlled trial of the 5-HT1A agonist R-137696 on symptoms, visceral hypersensitivity and on impaired accommodation in functional dyspepsia
J. Tack et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2009)
5-hydroxyindalpine, an agonist at the putative 5-HT1P receptor, has no activity on human recombinant monoamine receptors but accelerates distension-induced peristalsis in mouse isolated colon
N. A. Mitchell et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2009)
Distribution of serotonin receptors and interacting proteins in the human sigmoid colon
N. Chetty et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2009)
Translating 5-HT4 receptor pharmacology
G. J. Sanger
NEUROGASTROENTEROLOGY AND MOTILITY (2009)
Serotonin2C receptors in the medial prefrontal cortex facilitate cocaine-induced dopamine release in the rat nucleus accumbens
Gian Marco Leggio et al.
NEUROPHARMACOLOGY (2009)
Allosteric modulation of 5-HT1A receptors by zinc: Binding studies
Sergio Barrondo et al.
NEUROPHARMACOLOGY (2009)
5-HT7 receptor deletion enhances REM sleep suppression induced by selective serotonin reuptake inhibitors, but not by direct stimulation of 5-HT1A receptor
Jonathan Shelton et al.
NEUROPHARMACOLOGY (2009)
Region-specific changes in 5-HT1A agonist-induced Extracellular signal-Regulated Kinases 1/2 phosphorylation in rat brain: A quantitative ELISA study
Jaroslava Buritova et al.
NEUROPHARMACOLOGY (2009)
The 5-HT3 receptor - the relationship between structure and function
Nicholas M. Barnes et al.
NEUROPHARMACOLOGY (2009)
Role of ventral medial prefrontal cortex in incubation of cocaine craving
Eisuke Koya et al.
NEUROPHARMACOLOGY (2009)
Stress Impairs 5-HT2A Receptor-Mediated Serotonergic Facilitation of GABA Release in Juvenile Rat Basolateral Amygdala
Xiaolong Jiang et al.
NEUROPSYCHOPHARMACOLOGY (2009)
Editing of Serotonin 2C Receptor mRNA in the Prefrontal Cortex Characterizes High-Novelty Locomotor Response Behavioral Trait
Stella Dracheva et al.
NEUROPSYCHOPHARMACOLOGY (2009)
5-HT INHIBITION OF RAT INSULIN 2 PROMOTER Cre RECOMBINASE TRANSGENE AND PROOPIOMELANOCORTIN NEURON EXCITABILITY IN THE MOUSE ARCUATE NUCLEUS
K. Hisadome et al.
NEUROSCIENCE (2009)
Central 5-HT receptors in cardiovascular control during stress
Eugene Nalivaiko et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2009)
Colocalization of 5-HT1F receptor and calcitonin gene-related peptide in rat vestibular nuclei
Seong-Ki Ahn et al.
NEUROSCIENCE LETTERS (2009)
5-HT7 receptor activation inhibits mechanical hypersensitivity secondary to capsaicin sensitization in mice
Alex Brenchat et al.
PAIN (2009)
Serotonylation of Vascular Proteins Important to Contraction
Stephanie W. Watts et al.
PLOS ONE (2009)
5-Hydroxytryptamine Modulates Migration, Cytokine and Chemokine Release and T-Cell Priming Capacity of Dendritic Cells In Vitro and In Vivo
Tobias Mueller et al.
PLOS ONE (2009)
Role of Serotonin via 5-HT2B Receptors in the Reinforcing Effects of MDMA in Mice
Stephane Doly et al.
PLOS ONE (2009)
Functional variants of the serotonin receptor type 3A and B gene are associated with eating disorders
Christian Hammer et al.
PHARMACOGENETICS AND GENOMICS (2009)
Pharmacological characterization and determination of pharmacokinetic and pharmacodynamic relationship of PF-00885706, a novel partial agonist selective for the 5-HT4 receptor
Tohru Komada et al.
PHARMACOLOGICAL RESEARCH (2009)
The role of CGRP in the pathophysiology of migraine and efficacy of CGRP receptor antagonists as acute antimigraine drugs
Carlos M. Villalon et al.
PHARMACOLOGY & THERAPEUTICS (2009)
Current status of inverse agonism at serotonin2A (5-HT2A) and 5-HT2C receptors
V. J. Aloyo et al.
PHARMACOLOGY & THERAPEUTICS (2009)
Rapid modulation of spine morphology by the 5-HT2A serotonin receptor through kalirin-7 signaling
Kelly A. Jones et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
WAY-163909, a 5-HT2C agonist, enhances the preclinical potency of current antipsychotics
Steven M. Grauer et al.
PSYCHOPHARMACOLOGY (2009)
The effects of the selective 5-HT2C receptor antagonist SB 242084 on learned helplessness in male Fischer 344 rats
Paul V. Strong et al.
PSYCHOPHARMACOLOGY (2009)
Olanzapine-induced weight gain in the rat: role of 5-HT2C and histamine H1 receptors
Shona L. Kirk et al.
PSYCHOPHARMACOLOGY (2009)
Role of 5-HT receptor mechanisms in sub-chronic PCP-induced reversal learning deficits in the rat
Samantha L. McLean et al.
PSYCHOPHARMACOLOGY (2009)
Amisulpride is a potent 5-HT7 antagonist: relevance for antidepressant actions in vivo
Atheir I. Abbas et al.
PSYCHOPHARMACOLOGY (2009)
The 5-HT7 receptor and disorders of the nervous system: an overview
Peter B. Hedlund
PSYCHOPHARMACOLOGY (2009)
A Randomized, Double-Blind, Placebo-Controlled Trial to Evaluate the Efficacy, Safety, Tolerability, and Pharmacokinetic/Pharmacodynamic Effects of a Targeted Exposure of Intravenous Repinotan in Patients With Acute Ischemic Stroke Modified Randomized Exposure Controlled Trial (mRECT)
Philip Teal et al.
STROKE (2009)
The Role of the Dorsal Raphe Nucleus in the Development, Expression, and Treatment of L-dopa-Induced Dyskinesia in Hemiparkinsonian Rats
Karen L. Eskow et al.
SYNAPSE (2009)
Making a neuron: Cdk5 in embryonic and adult neurogenesis
Sebastian Jessberger et al.
TRENDS IN NEUROSCIENCES (2009)
'7TM Receptor Allostery: Putting Numbers to Shapeshifting Proteins
Terry P. Kenakin
TRENDS IN PHARMACOLOGICAL SCIENCES (2009)
Depletion of Serotonin and Selective Inhibition of 2B Receptor Suppressed Tumor Angiogenesis by Inhibiting Endothelial Nitric Oxide Synthase and Extracellular Signal-Regulated Kinase 1/2 Phosphorylation
Masanori Asada et al.
NEOPLASIA (2009)
Altered serotonin physiology in human breast cancers favors paradoxical growth and cell survival
Vaibhav P. Pai et al.
BREAST CANCER RESEARCH (2009)
The role of serotonin in intestinal luminal sensing and secretion
M. Berner Hansen et al.
ACTA PHYSIOLOGICA (2008)
Effect of impulsivity on cardiovascular and subjective reactivity to smoking cues
Neal Doran et al.
ADDICTIVE BEHAVIORS (2008)
Balancing drug risk and benefit: Toward refining the process of FDA decisions affecting patient care
Lawrence R. Schiller et al.
AMERICAN JOURNAL OF GASTROENTEROLOGY (2008)
Serotonin (5-HT) release and uptake measured by real-time electrochemical techniques in the rat ileum
Paul P. Bertrand et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)
5-HT4 receptor activation facilitates recovery from synaptic rundown and increases transmitter release from single varicosities of myenteric neurons
Jianhua Ren et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2008)
Identification of biomarkers of adrenocortical carcinoma using genomewide gene expression profiling
Gustavo G. Fernandez-Ranvier et al.
ARCHIVES OF SURGERY (2008)
The 5-HT2C receptor agonist WAY-163909 decreases impulsivity in the 5-choice serial reaction time test
Rachel Navarra et al.
BEHAVIOURAL BRAIN RESEARCH (2008)
Improvement of phencyclidine-induced social behaviour deficits in rats:: Involvement of 5-HT1A receptors
Shikha Snigdha et al.
BEHAVIOURAL BRAIN RESEARCH (2008)
A preliminary investigation into the effects of antipsychotics on sub-chronic phencyclidine-induced deficits in attentional set-shifting in female rats
Samantha L. McLean et al.
BEHAVIOURAL BRAIN RESEARCH (2008)
Molecular biology of 5-HT receptors
Jason Hannon et al.
BEHAVIOURAL BRAIN RESEARCH (2008)
The effects of the 5-HT6 receptor agonist EMD and the 5-HT7 receptor agonist AS19 on memory formation
A. Meneses et al.
BEHAVIOURAL BRAIN RESEARCH (2008)
The role of 5-HT1A receptors in learning and memory
Sven Ove Ogren et al.
BEHAVIOURAL BRAIN RESEARCH (2008)
The serotonin 5-HT7 receptor agonist LP-44 microinjected into the dorsal raphe nucleus suppresses REM sleep in the rat
Jaime M. Monti et al.
BEHAVIOURAL BRAIN RESEARCH (2008)
Effects of SB-269970, a 5-HT7 receptor antagonist, in mouse models predictive of antipsychotic-like in activity
Ruggero Galici et al.
BEHAVIOURAL PHARMACOLOGY (2008)
Serotonin systems upregulate the expression of hypothalamic NUCB2 via 5-HT2C receptors and induce anorexia via a leptin-independent pathway in mice
Katsunori Nonogaki et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2008)
Pharmacology of 5HT2C receptor-mediated ERK1/2 phosphorylation: Agonist-specific activation pathways and the impact of RNA editing
Tim D. Werry et al.
BIOCHEMICAL PHARMACOLOGY (2008)
Organic Background of Restrictive-Type Anorexia Nervosa Suggested by Increased Serotonin1A Receptor Binding in Right Frontotemporal Cortex of Both Lean and Recovered Patients: [18F]MPPF PET Scan Study
Bogdan Galusca et al.
BIOLOGICAL PSYCHIATRY (2008)
Increased expression of 5-HT6 receptors in the nucleus accumbens blocks the rewarding but not psychomotor activating properties of cocaine
Susan M. Ferguson et al.
BIOLOGICAL PSYCHIATRY (2008)
Inactivation of the 5-HT7 receptor partially blocks phencyclidine-induced disruption of prepulse inhibition
Svetlana Semenova et al.
BIOLOGICAL PSYCHIATRY (2008)
Frontolimbic serotonin 2A receptor binding in healthy subjects is associated with personality risk factors for affective disorder
Vibe G. Frokjaer et al.
BIOLOGICAL PSYCHIATRY (2008)
Cyclic guanidines as dual 5-HT5A/5-HT7 receptor ligands: Optimising brain penetration
Jens-Uwe Peters et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2008)
The existence of a local 5-hydroxytryptaminergic system in peripheral arteries
W. Ni et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
5-HT4-elicited positive inotropic response is mediated by cAMP and regulated by PDE3 in failing rat and human cardiac ventricles
F. Afzal et al.
BRITISH JOURNAL OF PHARMACOLOGY (2008)
Serotonin regulates macrophage-mediated angiogenesis in a mouse model of colon cancer allografts
Antonio Nocito et al.
CANCER RESEARCH (2008)
Both 5-hydroxytryptamine 5-HT2A and 5-HT1B receptors are involved in the vasoconstrictor response to 5-HT in the human isolated internal thoracic artery
Naoko Tanaka et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2008)
Effects of 5-hydroxytryptamine (serotonin) type 3 antagoniosts on symptom relief and constipation in nonconstipated irritable bowel syndrome: A systematic review and meta-analysis of randomized controlled trials
Viola Andresen et al.
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY (2008)
Serotonergic agents and the irritable bowel syndrome: what goes wrong?
Robin Spiller
CURRENT OPINION IN PHARMACOLOGY (2008)
Mosapride - In gastrointestinal disorders
Monique P. Curran et al.
DRUGS (2008)
Serotonin 5-HT2C receptor agonist promotes hypophagia via downstream activation of melanocortin 4 receptors
Daniel D. Lam et al.
ENDOCRINOLOGY (2008)
Synergistic impairment of glucose homeostasis in ob/ob mice lacking functional serotonin 2C receptors
Jennifer M. Wade et al.
ENDOCRINOLOGY (2008)
Characterization of contractile 5-hydroxytryptamine receptor subtypes in the in situ autoperfused kidney in the anaesthetized rat
Asuncion Moran et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Agonist-directed trafficking of signalling at serotonin 5-HT2A, 5-HT2B and 5-HT2C-VSV receptors mediated Gq/11 activation and calcium mobilisation in CHO cells
Didier Cussac et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2008)
Fenfluramine: riddle or Rosetta stone?
E. K. Weir et al.
EUROPEAN RESPIRATORY JOURNAL (2008)
Modulation of bleomycin-induced lung fibrosis by serotonin receptor antagonists in mice
A. Fabre et al.
EUROPEAN RESPIRATORY JOURNAL (2008)
5-Hydroxytryptamine (5HT)-induced valvulopathy: Compositional. valvular alterations are associated with 5HT2B receptor and 5HT transporter transcript changes in Sprague-Dawley rats
Chandikumar S. Elangbam et al.
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY (2008)
The serotonin 5-HT2B receptor controls bone mass via osteoblast recruitment and proliferation
C. Collet et al.
FASEB JOURNAL (2008)
Cloning, genomic organization and functionality of 5-HT7 receptor splice variants from mouse brain
Evelien Gellynck et al.
GENE (2008)
The discovery and development of the triptans, a major therapeutic breakthrough
Patrick P. A. Humphrey
HEADACHE (2008)
Effects of 5-HT drugs in prefrontal cortex during memory formation and the ketamine amnesia-model
Gustavo Liy-Salmeron et al.
HIPPOCAMPUS (2008)
First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome
Johannes Kapeller et al.
HUMAN MOLECULAR GENETICS (2008)
Serotonin 5-HT2B receptor blockade prevents reactive oxygen species-induced cardiac hypertrophy in mice
Laurent Monassier et al.
HYPERTENSION (2008)
Genetic polymorphisms in the 5-hydroxytryptamine type 3B receptor gene and paroxetine-induced nausea
Misuzu Tanaka et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2008)
Structural determinants of Ca2+ permeability and conduction in the human 5-hydroxytryptamine type 3A receptor
Matthew R. Livesey et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
Modular design of cys-loop ligand-gated ion channels:: Functional 5-HT3 and GABA ρ1 receptors lacking the large cytoplasmic M3M4 loop
Michaela Jansen et al.
JOURNAL OF GENERAL PHYSIOLOGY (2008)
Structural modifications of N-(1,2,3,4-tetrahydronaphthalen-1-yl)-4-aryl-1-piperazinehexanamides:: Influence on lipophilicity and 5-HT7 receptor activity.: Part III
Marcello Leopoldo et al.
JOURNAL OF MEDICINAL CHEMISTRY (2008)
Pathogenic mechanisms of pulmonary arterial hypertension
Stephen Y. Chan et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2008)
Dysregulated Editing of Serotonin 2C Receptor mRNAs Results in Energy Dissipation and Loss of Fat Mass
Yukio Kawahara et al.
JOURNAL OF NEUROSCIENCE (2008)
Targeting of the 5-HT1A serotonin receptor to neuronal dendrites is mediated by Yif1B
Damien Carrel et al.
JOURNAL OF NEUROSCIENCE (2008)
Serotonin 5-HT2B receptors are required for 3,4-methylenedioxymethamphetamine-induced hyperlocomotion and 5-HT release in vivo and in vitro
Stephane Doly et al.
JOURNAL OF NEUROSCIENCE (2008)
A transcriptome database for astrocytes, neurons, and oligodendrocytes: A new resource for understanding brain development and function
John D. Cahoy et al.
JOURNAL OF NEUROSCIENCE (2008)
Effects of a cannabinoid1 receptor antagonist and serotonin2C receptor agonist alone and in combination on motivation for palatable food:: A dose-addition analysis study in mice
Sara Jane Ward et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Lorcaserin, a novel selective human 5-Hydroxytryptamine2C agonist:: In vitro and in vivo pharmacological characterization
William J. Thomsen et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Serotonin increases GABA release in rat entorhinal cortex by inhibiting interneuron TASK-3 K+ channels
Pan-Yue Deng et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2008)
Sumatriptan inhibits synaptic transmission in the rat midbrain periaqueductal grey
Hyo-Jin Jeong et al.
MOLECULAR PAIN (2008)
Apneusis responding to buspirone in multiple sclerosis
R. J. O'Sullivan et al.
MULTIPLE SCLEROSIS JOURNAL (2008)
Identification of a serotonin/glutamate receptor complex implicated in psychosis
Javier Gonzalez-Maeso et al.
NATURE (2008)
Hormones of the gut-brain axis as targets for the treatment of upper gastrointestinal disorders
Gareth J. Sanger et al.
NATURE REVIEWS DRUG DISCOVERY (2008)
The in vivo gastrointestinal activity of TD-5108, a selective 5-HT4 receptor agonist with high intrinsic activity
D. T. Beattie et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2008)
Serotonin pharmacology in the gastrointestinal tract: a review
D. T. Beattie et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2008)
Identification and functional significance of N-glycosylation of the 5-ht5A receptor
Alice C. Dutton et al.
NEUROCHEMISTRY INTERNATIONAL (2008)
Serotonergic signalling in the stomach and duodenum of patients with gastroparesis
N. Van Lelyveld et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2008)
5-HT4 receptor agonists:: similar but not the same
J. H. De Maeyer et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2008)
5-HT2CRs Expressed by Pro-Opiomelanocortin Neurons Regulate Energy Homeostasis
Yong Xu et al.
NEURON (2008)
5HT2 receptor activation facilitates P2X receptor mediated excitatory neurotransmission to cardiac vagal neurons in the nucleus ambiguus
Olga Dergacheva et al.
NEUROPHARMACOLOGY (2008)
Insights into the regulation of 5-HT2A serotonin receptors by scaffolding proteins and kinases
John A. Allen et al.
NEUROPHARMACOLOGY (2008)
Fine-tuning serotonin2c receptor function in the brain: Molecular and functional implications
Kelly A. Berg et al.
NEUROPHARMACOLOGY (2008)
An update on the role of the 5-hydroxytryptamine6 receptor in cognitive function
Kevin C. F. Fone
NEUROPHARMACOLOGY (2008)
5-HT4 receptors: History, molecular pharmacology and brain functions
Joel Bockaert et al.
NEUROPHARMACOLOGY (2008)
Effects of serotonin in failing cardiac ventricle: Signalling mechanisms and potential therapeutic implications
Finn Olav Levy et al.
NEUROPHARMACOLOGY (2008)
Altered serotonin 2C receptor RNA splicing in suicide: association with editing
Stella Dracheva et al.
NEUROREPORT (2008)
The effects of photic and nonphotic stimuli in the 5-HT7 receptor knockout mouse
M. Gardani et al.
NEUROSCIENCE (2008)
5-HT6 receptor antagonists as novel cognitive enhancing agents for Alzheimer's disease
Neil Upton et al.
NEUROTHERAPEUTICS (2008)
Alternative splicing and exon duplication generates 10 unique porcine 5-HT4 receptor splice variants including a functional homofusion variant
Joris H. De Maeyer et al.
PHYSIOLOGICAL GENOMICS (2008)
Sucrose intake and fasting glucose levels in 5-HT1A and 5-HT1B receptor mutant mice
Anita J. Bechtholt et al.
PHYSIOLOGY & BEHAVIOR (2008)
Serotonin type 3 receptor genes:: HTR3A, B, C, D, E
Beate Niesler et al.
PHARMACOGENOMICS (2008)
Selective 5-HT6 receptor ligands:: Progress in the development of a novel pharmacological approach to the treatment of obesity and related metabolic disorders
D. J. Heal et al.
PHARMACOLOGY & THERAPEUTICS (2008)
Agonist-directed signaling of the serotonin 2A receptor depends on β-arrestin-2 interactions in vivo
Cullen L. Schmid et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
High-frequency HTR3B variant associated with major depression dramatically augments the signaling of the human 5-HT3AB receptor
Karen Krzywkowski et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Alternative splicing of the G protein-coupled receptor superfamily in human airway smooth muscle diversifies the complement of receptors
Richard Einstein et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Antagonism of dopamine D2 receptor/β-arrestin 2 interaction is a common property of clinically effective antipsychotics
Bernard Masri et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Genetic evaluation of the serotonergic system in chronic fatigue syndrome
Alicia K. Smith et al.
PSYCHONEUROENDOCRINOLOGY (2008)
Identification of 5-HT3 receptors on human platelets: Increased surface immunoreactivity after activation with adenosine diphosphate (ADP) and thrombin receptor-activating peptide (TRAP)
Christian Stratz et al.
THROMBOSIS AND HAEMOSTASIS (2008)
5-hydroxytryptamine and the gastrointestinal tract: where next?
Gareth J. Sanger
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Signaling at G-protein-coupled serotonin receptors: recent advances and future research directions
Mark J. Millan et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
5-hydroxytryptamine and cardiovascular regulation
Andrew G. Ramage et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
A role for the 5-HT1A, 5-HT4 and 5-HT6 receptors in learning and memory
Madeleine V. King et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2008)
Interferon β1-a and selective anti-5HT2a receptor antagonists inhibit infection of human glial cells by JC virus
B. A. O'Hara et al.
VIRUS RESEARCH (2008)
Neuropharmacological profile of novel and selective 5-HT6 receptor agonists:: WAY-181187 and WAY-208466
Lee E. Schechter et al.
NEUROPSYCHOPHARMACOLOGY (2008)
The 5-HT2C receptor agonist Ro60-0175 reduces cocaine self-administration and reinstatement induced by the stressor yohimbine, and contextual cues
Paul J. Fletcher et al.
NEUROPSYCHOPHARMACOLOGY (2008)
A conservative, single-amino acid substitution in the second cytoplasmic domain of the human serotonin2C receptor alters both ligand-dependent and -independent receptor signaling
Kelly A. Berg et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2008)
Increased serotonin 2C receptor mRNA editing: a possible risk factor for suicide
S. Dracheva et al.
MOLECULAR PSYCHIATRY (2008)
Gene expression profiling in uveal melanoma:: Two regions on 3p related to prognosis
Walter van Gils et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2008)
The promnesic effect of G-protein-coupled 5-HT4 receptors activation is mediated by a potentiation of learning-induced spine growth in the mouse hippocampus
Leonardo Restivo et al.
NEUROPSYCHOPHARMACOLOGY (2008)
Synthesis and Evaluation of [C-11]SB207145 as the First In Vivo Serotonin 5-HT4 Receptor Radioligand for PET Imaging in Man
A. D. Gee et al.
CURRENT RADIOPHARMACEUTICALS (2008)
Differential regulation of the mesoaccumbens dopamine circuit by serotonin2C receptors in the ventral tegmental area and the nucleus accumbens: An in vivo microdialysis study with cocaine
Sylvia Navailles et al.
NEUROPSYCHOPHARMACOLOGY (2008)
Pro-cognitive effects of 5-HT6 receptor antagonists in the social recognition procedure in rats: implication of the frontal cortex
Florence Loiseau et al.
PSYCHOPHARMACOLOGY (2008)
Anxiety as a developmental disorder
E. David Leonardo et al.
NEUROPSYCHOPHARMACOLOGY (2008)
Stimulation of serotonin(2C) receptors influences cocaine-seeking behavior in response to drug-associated stimuli in rats
Silvia Burbassi et al.
PSYCHOPHARMACOLOGY (2008)
5-HT1B receptor subtype and aging in rat resistance vessels
Guglielmina Froldi et al.
PHARMACOLOGY (2008)
Modifying Ligand-Induced and Constitutive Signaling of the Human 5-HT4 Receptor
Wei Chun Chang et al.
PLOS ONE (2007)
Important messages in the 'post':: recent discoveries in 5-HT neurone feedback control
Trevor Sharp et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2007)
Stimulation of 5-HT2C receptors attenuates cue and cocaine-primed reinstatement of cocaine-seeking behavior in rats
Janet L. Neisewander et al.
BEHAVIOURAL PHARMACOLOGY (2007)
Heterogeneous rate of protein evolution in serotonin genes
Aida M. Andres et al.
MOLECULAR BIOLOGY AND EVOLUTION (2007)
Opposing effects of 5-HT2A and 5-HT2C receptor antagonists in the rat and mouse on premature responding in the five-choice serial reaction time test
Paul J. Fletcher et al.
PSYCHOPHARMACOLOGY (2007)
Appetite stimulants in cystic fibrosis: a systematic review
R. S. Chinuck et al.
JOURNAL OF HUMAN NUTRITION AND DIETETICS (2007)
Serotonin responsiveness through 5-HT2A and 5-HT4 receptors is differentially regulated in hypertrophic and failing rat cardiac ventricle
Trond Brattelid et al.
JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY (2007)
Atypical antipsychotics attenuate a sub-chronic PCP-induced cognitive deficit in the novel object recognition task in the rat
B. Grayson et al.
BEHAVIOURAL BRAIN RESEARCH (2007)
Inhibition of human 5-HT3A and 5-HT3AB receptors by etomidate, propofol and pentobarbital
Dirk Ruesch et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Serotonin 2C receptor agonists improve type 2 diabetes via melanocortin-4 receptor signaling pathways
Ligang Zhou et al.
CELL METABOLISM (2007)
5-HT2c receptor agonists as an innovative approach for psychiatric disorders
Sharon Rosenzweig-Lipson et al.
DRUG NEWS & PERSPECTIVES (2007)
The association of serotonin transporter genetic polymorphisms and irritable bowel syndrome and its influence on tegaserod treatment in chinese patients
Yuyuan Li et al.
DIGESTIVE DISEASES AND SCIENCES (2007)
Intestinal nutrients elicit satiation through concomitant activation of CCK1 and 5-HT3 receptors
David M. Savastano et al.
PHYSIOLOGY & BEHAVIOR (2007)
Anorexia induced by activation of serotonin 5-HT4 receptors is mediated by increases in CART in the nucleus accumbens
Alexandra Jean et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Serotonin increases L-type Ca2+ current and SR Ca2+ content through 5-HT4 receptors in failing rat ventricular cardiomyocytes
Jon Arne Kro Birkeland et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2007)
Cardiovascular responses produced by 5-hydroxytriptamine: a pharmacological update on the receptors/mechanisms involved and therapeutic implications
Carlos M. Villalon et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2007)
SB-649915-B, a novel 5-HT1A/B Autoreceptor antagonist and serotonin Reuptake inhibitor, is Anxiolytic and displays fast onset activity in the rat high light social interaction test
Kathryn R. Starr et al.
NEUROPSYCHOPHARMACOLOGY (2007)
Effects of Ondansetron on gastric tone and motility changes induced by a prolonged intraduodenal infusion of nutrients.: Results of a placebo-controlled study
Guillaume Savoye et al.
DIGESTIVE DISEASES AND SCIENCES (2007)
Serotonin 5-hydroxytryptamine2C receptor signaling in hypothalamic proopiomelanocortin neurons:: Role in energy homeostasis in females
Jian Qiu et al.
MOLECULAR PHARMACOLOGY (2007)
Effect of impulsivity on craving and behavioral reactivity to smoking cues
Neal Doran et al.
PSYCHOPHARMACOLOGY (2007)
Ion channel diversity, channel expression and function in the choroid plexuses
Ian D. Millar et al.
FLUIDS AND BARRIERS OF THE CNS (2007)
Differential subcellular localization of RIC-3 Isoforms and their role in determining 5-HT3 receptor composition
Aixin Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Serotonin4 (5-HT4) receptor Agonists are putative antidepressants with a rapid onset of action
Guillaume Lucas et al.
NEURON (2007)
Mirtazapine in progressive multifocal leukoencephalopathy associated with polycythemia vera
Susama Verma et al.
JOURNAL OF INFECTIOUS DISEASES (2007)
Endogenous serotonin excites striatal cholinergic interneurons via the activation of 5-HT 2C, 5-HT6, and 5-HT7 serotonin receptors: implications for extrapyramidal side effects of serotonin reuptake inhibitors
Paola Bonsi et al.
NEUROPSYCHOPHARMACOLOGY (2007)
6-hydroxybuspirone is a major active metabolite of buspirone:: Assessment of pharmacokinetics and 5-hydroxytryptamine1A receptor occupancy in rats
Harvey Wong et al.
DRUG METABOLISM AND DISPOSITION (2007)
Dopamine and serotonin receptor binding and antipsychotic efficacy
Neil M. Richtand et al.
NEUROPSYCHOPHARMACOLOGY (2007)
Serotonin and neuroprotection in functional bowel disorders
M. D. Gershon et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2007)
The partial 5-HT1A agonist buspirone reduces the expression and development of I-DOPA-induced dyskinesia in rats and improves I-DOPA efficacy
Karen L. Eskow et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2007)
Serotonin 5-HT2C receptor homodimerization is not regulated by agonist or inverse agonist treatment
Katharine Herrick-Davis et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Promoting effects of serotonin on hematopoiesis:: Ex vivo expansion of cord blood CD34+ stem/progenitor cells, proliferation of bone marrow stromal cells, and antiapoptosis
Mo Yang et al.
STEM CELLS (2007)
Serotonin 2B receptor: Upregulated with age and hearing loss in mouse auditory system
Sherif F. Tadros et al.
NEUROBIOLOGY OF AGING (2007)
Increased expression of 5-HT6 receptors in the rat dorsomedial striatum impairs instrumental learning
Ellen S. Mitchell et al.
NEUROPSYCHOPHARMACOLOGY (2007)
Serotonin 5-HT2C receptors regulate anxiety-like behavior
L. K. Heisler et al.
GENES BRAIN AND BEHAVIOR (2007)
Augmentation of SSRI effects on serotonin by 5-HT2C antagonists:: Mechanistic studies
Thomas I. F. H. Cremers et al.
NEUROPSYCHOPHARMACOLOGY (2007)
Activation of nucleus tractus solitarius 5-HT2A but not other 5-HT2 receptor subtypes inhibits the sympathetic activity in rats
M.-A. Comet et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
An inhibitory compound against the interaction between Gas and the third intracellular loop region of serotonin receptor subtype 6 (5-HT6) disrupts the signaling pathway of 5-HT6
Yun Hee Choi et al.
EXPERIMENTAL AND MOLECULAR MEDICINE (2007)
Serotonin activates the hypothalamic-pituitary-adrenal axis via serotonin 2C receptor stimulation
Lora K. Heisler et al.
JOURNAL OF NEUROSCIENCE (2007)
Characterization of the serotonin transporter knockout rat: A selective change in the functioning of the serotonergic system
J. R. Homberg et al.
NEUROSCIENCE (2007)
Serotonin2C receptor localization in GABA neurons of the rat medial prefrontal cortex:: Implications for understanding the neurobiology of addiction
S. Liu et al.
NEUROSCIENCE (2007)
Mechanism of the 5-hydroxytryptamine 2A receptor-mediated facilitation of synaptic activity in prefrontal cortex
Jean-Claude Beique et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2007)
Antidepressant-like effects of the novel, selective, 5-HT2C receptor agonist WAY-163909 in rodents
Sharon Rosenzweig-Lipson et al.
PSYCHOPHARMACOLOGY (2007)
Functional selectivity of hallucinogenic phenethylamine and phenylisopropylamine derivatives at human 5-hydroxytryptamine (5-HT)2A and 5-HT2C receptors
Pablo R. Moya et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Modified receptor internalization upon coexpression of 5-HT1B receptor and 5-HT2B receptors
Agnes Janoshazi et al.
MOLECULAR PHARMACOLOGY (2007)
Novel benzodifuran analogs as potent 5-HT2A receptor agonists with ocular hypotensive activity
Zixia Feng et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2007)
Quantitative mRNA analysis of serotonin 5-HT4 receptor isoforms, calcium handling proteins and ion channels in human atrial fibrillation
Frank Lezoualc'h et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2007)
Effective adjunctive use of tandospirone with perospirone for enhancing verbal memory and quality of life in schizophrenia
Tomiki Sumiyoshi et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2007)
Selective blockade of 5-hydroxytryptamine (5-HT)7 receptors enhances 5-HT transmission, antidepressant-like behavior, and rapid eye movement sleep suppression induced by citalopram in rodents
Pascal Bonaventure et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Expression of mRNA encoding G protein-coupled receptors involved in congestive heart failure - A quantitative RT-PCR study and the question of normalisation
Trond Brattelid et al.
BASIC RESEARCH IN CARDIOLOGY (2007)
5-HT2C receptor activation inhibits appetitive and consummatory components of feeding and increases brain c-fos immunoreactivity in mice
Elizabeth M. Somerville et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2007)
5-HT1A receptor agonist properties of antipsychotics determined by [35S]GTPγS binding in rat hippocampal membranes
Yuji Odagaki et al.
CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY (2007)
Exaggerated 5-HT1A but normal 5-HT2A receptor activity in individuals ill with anorexia nervosa
Ursula F. Bailer et al.
BIOLOGICAL PSYCHIATRY (2007)
Simultaneous blockade of 5-HT1A/B receptors and 5-HT transporters results in acute increases in extracellular 5-HT in both rats and guinea pigs:: in vivo characterization of the novel 5-HT1A/B receptor antagonist/5-HT transport inhibitor SB-649915-B
Zoe A. Hughes et al.
PSYCHOPHARMACOLOGY (2007)
F15063, a compound with D2/D3 antagonist, 5-HT1A agonist and D4 partial agonist properties:: (III) Activity in models of cognition and negative symptoms
R. Depoortere et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Expression of 5-HT7 receptor mRNA in the hamster brain:: Effect of aging and association with calbindin-D28K expression
Marilyn J. Duncan et al.
BRAIN RESEARCH (2007)
Distribution of serotonin 5-HT2C receptors in the ventral tegmental area
M. J. Bubar et al.
NEUROSCIENCE (2007)
Serotonin provides an accessory signal to enhance T-cell activation by signaling through the 5-HT7 receptor
Matilde Leon-Ponte et al.
BLOOD (2007)
The role of 5-HT7 receptors in the control of seizures
Danka Pericic et al.
BRAIN RESEARCH (2007)
Biochemical and behavioral evidence for antidepressant-like effects of 5-HT6 receptor stimulation
Per Svenningsson et al.
JOURNAL OF NEUROSCIENCE (2007)
The discovery of a new drug class for the acute treatment of migraine
Patrick P. A. Humphrey
HEADACHE (2007)
Identification of 5-HT3A and 5-HT3B receptor subunits in human hippocampus
Catherine A. Brady et al.
NEUROPHARMACOLOGY (2007)
Naturally occurring variations in the human 5-HT3A gene profoundly impact 5-HT3 receptor function and expression
Karen Krzywkowski et al.
PHARMACOGENETICS AND GENOMICS (2007)
Prefrontal cortical network activity: Opposite effects of psychedelic hallucinogens and D1/D5 dopamine receptor activation
E. K. Lambe et al.
NEUROSCIENCE (2007)
The effects of non-medically used psychoactive drugs on monoamine neurotransmission in rat brain
Fumiko Nagai et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2007)
Mapping 5-HT inputs to enteric neurons of the guinea-pig small intestine
K. B. Neal et al.
NEUROSCIENCE (2007)
Functional CRF receptors in BON cells stimulate serotonin release
Bengt von Mentzer et al.
BIOCHEMICAL PHARMACOLOGY (2007)
The 5-HT7 receptor influences stereotypic behavior in a model of obsessive-compulsive disorder
Peter B. Hedlund et al.
NEUROSCIENCE LETTERS (2007)
Comparison of 5-HT4 and 5-HT7 receptor expression and function in the circular muscle of the human colon
Helen R. Irving et al.
LIFE SCIENCES (2007)
Native rat hippocampal 5-HT1A receptors show constitutive activity
Jean-Claude Martel et al.
MOLECULAR PHARMACOLOGY (2007)
Role of the anterior cingulate and medial orbitofrontal cortex in processing drug cues in cocaine addiction
R. Z. Goldstein et al.
NEUROSCIENCE (2007)
Selective activation of 5-ht2C receptors stimulates GABA-ERGIC function in the rat substant a nigra pars reticulata:: A combined in vivo electrophysiological and neurochemical study
R. W. Invernizzi et al.
NEUROSCIENCE (2007)
The novel cellular mechanism of human 5-HT6 receptor through an interaction with Fyn
Hyung-Mun Yun et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
p11 (S100A10) - an inducible adaptor protein that modulates neuronal functions
Per Svenningsson et al.
CURRENT OPINION IN PHARMACOLOGY (2007)
CP-809,101, a selective 5-HT2C agonist, shows activity in animal models of antipsychotic activity
Judith A. Siuciak et al.
NEUROPHARMACOLOGY (2007)
AL-34662: A potent, selective, and efficacious ocular hypotensive serotonin-2 receptor agonist
Najam A. Sharif et al.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2007)
Serotonin and epilepsy
Gyorgy Bagdy et al.
JOURNAL OF NEUROCHEMISTRY (2007)
Human mast cells are capable of serotonin synthesis and release
Nataliya M. Kushnir-Sukhov et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2007)
Tegaserod for constipation-predominant irritable bowel syndrome
Pramodini B. Kale-Pradhan et al.
PHARMACOTHERAPY (2007)
Hallucinogens recruit specific cortical 5-HT2A receptor-mediated signaling pathways to affect behavior
Javier Gonzalez-Maeso et al.
NEURON (2007)
Pharmacologic mechanisms of serotonergic regulation of dopamine neurotransmission
K. D. Alex et al.
PHARMACOLOGY & THERAPEUTICS (2007)
Novel interaction between the human 5-HT7 receptor isoforms and PLAC-24/eIF3k
Kim De Martelaere et al.
CELLULAR SIGNALLING (2007)
Tissue-specific alternative promoters of the serotonin receptor gene HTR3B in human brain and intestine
Mladen Vassilev Tzvetkov et al.
GENE (2007)
Sarizotan as a treatment for dyskinesias in Parkinson's disease:: A double-blind placebo-controlled trial
Christopher G. Goetz et al.
MOVEMENT DISORDERS (2007)
Pharmacodynamic effects of a novel prokinetic 5-HT4 receptor agonist, ATI-7505, in humans
M. Camilleri et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2007)
Intractable nausea and vomiting successfully treated with granisetron 5-hydroxytryptamine type 3 receptor antagonists in Palliative Medicine
Deans Buchanan
PALLIATIVE MEDICINE (2007)
Sensory transmission in the gastrointestinal tract
L. A. Blackshaw et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2007)
Effects of treatment with a 5-HT4 receptor antagonist in heart failure
J. A. K. Birkeland et al.
BRITISH JOURNAL OF PHARMACOLOGY (2007)
Serotoninergic receptors on human airway epithelial cells
Hans Bayer et al.
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY (2007)
SLV313 (1-(2,3-dihydro-benzo[1,4]dioxin-5-yl)-4-[5-(4-fluoro-phenyl)-pyridin-3-ylmethyl]-piperazine monohydrochloride): A novel dopamine D-2 receptor antagonist and 5-HT1A receptor agonist potential antipsychotic drug
Andrew C. McCreary et al.
NEUROPSYCHOPHARMACOLOGY (2007)
VRX-03011, a novel 5-HT4 agonist, enhances memory and hippocampal acetylcholine efflux
Eric G. Mohler et al.
NEUROPHARMACOLOGY (2007)
Ca2+-calmodulin and Janus kinase 2 are required for activation of sodium-proton exchange by the G(i)-coupled 5-hydroxytryptamine(1a) receptor
Justin H. Turner et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
WAY-163909 [(7bR, 10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta[b][1,4]diazepino[6,7,1hi]indole]: A novel 5-hydroxytryptamine 2C receptor-selective agonist with preclinical antipsychotic-like activity
Karen L. Marquis et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2007)
Stimulation of growth hormone release by 5-hydroxytryptamine (5-HT) in cultured rat anterior pituitary cell aggregates: Evidence for mediation by 5-HT2B, 5-HT7, 5-HT1B, and ketanserin-sensitive receptors
A. Papageorgiou et al.
ENDOCRINOLOGY (2007)
Effect of tryptophan hydroxylase 1 deficiency on the development of hypoxia-induced pulmonary hypertension
Ian Morecroft et al.
HYPERTENSION (2007)
The serotonin signaling system: From basic understanding to drug development-for functional GI disorders
Michael D. Gershon et al.
GASTROENTEROLOGY (2007)
Human 5-HT4 and 5-HT7 receptor splice vairants: Are they important?
Ian M. Coupar et al.
CURRENT NEUROPHARMACOLOGY (2007)
Sub-chronic psychotomimetic phencyclidine induces deficits in reversal learning and alterations in parvalbumin-immunoreactive expression in the rat
Z. Abdul-Monim et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2007)
The 5-HT3 receptor as a therapeutic target
Andrew J. Thompson et al.
EXPERT OPINION ON THERAPEUTIC TARGETS (2007)
Constitutive deletion of the serotonin-7 (5-HT7) receptor decreases electrical and chemical seizure thresholds
Jeffrey M. Witkin et al.
EPILEPSY RESEARCH (2007)
In vitro continuous amperometric monitoring of 5-hydroxytryptamine release from enterochromaffin cells of the guinea pig ileum
Bhavik Anil Patel et al.
ANALYST (2007)
Serotonergic drugs - Effects on appetite expression and use for the treatment of obesity
Jason C. G. Halford et al.
DRUGS (2007)
Fibrotic heart-valve reactions to dopamine-agonist treatment in Parkinson's disease
Angelo Antonini et al.
LANCET NEUROLOGY (2007)
Chronic 5-HT6 receptor modulation by E-6837 induces hypophagia and sustained weight loss in diet-induced obese rats
Angels Fisas et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Rapid desensitization of somatodendritic 5-HT1A receptors by chronic administration of the high-efficacy 5-HT1A agonist, F13714:: a microdialysis study in the rat
M-B Assie et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Anxiolytic activity of a novel potent serotonin 5-HT2C receptor antagonist FR260010:: A comparison with diazepam and buspirone
Katsuya Harada et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
SB-399885 is a potent, selective 5-HT6 receptor antagonist with cognitive enhancing properties in aged rat water maze and novel object recognition models
Warren D. Hirst et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Potential anxiolytic and antidepressant effects of the selective 5-HT7 receptor antagonist SB 269970 after intrahippocampal administration to rats
Anna Wesolowska et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Deletion of the serotonin 2c receptor from transgenic mice overexpressing leptin does not affect their lipodystrophy but exacerbates their diet-induced obesity
Biao Wang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2006)
In vitro characterization of SLV308 (7-[4-methyl-1-piperazinyl]-2(3H)-benzoxazolone, monohydrochloride):: A novel partial dopamine D2 and D3 receptor agonist and serotonin 5-HT1A receptor agonist
Jeffrey C. Glennon et al.
SYNAPSE (2006)
5-HT1B receptors play a prominent role in the proliferation of T-lymphocytes
Jun Yin et al.
JOURNAL OF NEUROIMMUNOLOGY (2006)
Use of a serotonin 1A receptor agonist to treat restless legs syndrome
Katsutoshi Shioda et al.
JOURNAL OF CLINICAL PSYCHOPHARMACOLOGY (2006)
Serotonin-2 (5-HT2) receptor-mediated signal transduction in human ciliary muscle cells:: Role in ocular hypotension
Najam A. Sharif et al.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2006)
Serotonin 1A receptor availability in patients with schizophrenia and schizo-affective disorder:: a positron emission tomography imaging study with [11C]WAY 100635
W. Gordon Frankle et al.
PSYCHOPHARMACOLOGY (2006)
Cortical serotonin7, 1D and 1F receptors:: Effects of schizophrenia, suicide and antipsychotic drug treatment
Brian Dean et al.
SCHIZOPHRENIA RESEARCH (2006)
Neuronal 5-HT metabotropic receptors:: fine-tuning of their structure, signaling, and roles in synaptic modulation
Joel Bockaert et al.
CELL AND TISSUE RESEARCH (2006)
Serotonin 5-HT2A receptor activation induces 2-arachidonoylglycerol release through a phospholipase c-dependent mechanism
Jason C. Parrish et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Mechanical stress enhances serotonin 2B receptor modulating brain natriuretic peptide through nuclear factor-κB in cardiomyocytes
Yao-Jen Liang et al.
CARDIOVASCULAR RESEARCH (2006)
5-hydroxytryptamine induces mast cell adhesion and migration
Nataliya M. Kushnir-Sukhov et al.
JOURNAL OF IMMUNOLOGY (2006)
Do polymorphisms in the human 5-HT3 genes contribute to pathological phenotypes?
K. Krzywkowski
BIOCHEMICAL SOCIETY TRANSACTIONS (2006)
Effect of serotonin on the differentiation of human monocytes into dendritic cells
N. Katoh et al.
CLINICAL AND EXPERIMENTAL IMMUNOLOGY (2006)
Systemic morphine produce antinociception mediated by spinal 5-HT7, but not 5-HT1A and 5-HT2 receptors in the spinal cord
A. Dogrul et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Treatment of nausea and vomiting: Gaps in our knowledge
Gareth J. Sanger et al.
AUTONOMIC NEUROSCIENCE-BASIC & CLINICAL (2006)
Induction of indefinite survival of fully mismatched cardiac allografts and generation of regulatory cells by sarpogrelate hydrochloride
Takurin Akiyoshi et al.
TRANSPLANTATION (2006)
Novel pharmacological targets for the treatment of Parkinson's disease
Anthony H. V. Schapira et al.
NATURE REVIEWS DRUG DISCOVERY (2006)
Effect of 5-HT1A receptor gene polymorphism on negative and depressive symptom response to antipsychotic treatment of drug-naive psychotic patients
Gavin P. Reynolds et al.
AMERICAN JOURNAL OF PSYCHIATRY (2006)
New and future migraine therapy
Nabih M. Ramadan et al.
PHARMACOLOGY & THERAPEUTICS (2006)
Role of the conserved NPxxY motif of the 5-HT2A receptor in determining selective interaction with isoforms of ADP-ribosylation factor (ARF)
Melanie S. Johnson et al.
CELLULAR SIGNALLING (2006)
Serotonin 5-HT2C receptor homodimer biogenesis in the endoplasmic reticulum -: Real-time visualization with confocal fluorescence resonance energy transfer
Katharine Herrick-Davis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
5-HT4 receptor agonists enhance both cholinergic and nitrergic activities in human isolated colon circular muscle
S. Cellek et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2006)
Antipsychotic-like vs cataleptogenic actions in mice of novel antipsychotics having D2 antagonist and 5-HT1A agonist properties
Laurent Bardin et al.
NEUROPSYCHOPHARMACOLOGY (2006)
A role for serotonin (5-HT) in hepatic stellate cell function and liver fibrosis
Richard G. Ruddell et al.
AMERICAN JOURNAL OF PATHOLOGY (2006)
Identification of neurons that express 5-hydroxytryptamine4 receptors in intestine
Daniel P. Poole et al.
CELL AND TISSUE RESEARCH (2006)
The effect of 5-hydroxytryptamine 3A and 3B receptor genes on nausea induced by paroxetine
T. Sugai et al.
PHARMACOGENOMICS JOURNAL (2006)
Am5-HT7:: molecular and pharmacological characterization of the first serotonin receptor of the honeybee (Apis mellifera)
Jana Schlenstedt et al.
JOURNAL OF NEUROCHEMISTRY (2006)
Regional differences in the coupling of 5-hydroxytryptamine-1A receptors to G proteins in the rat brain
Clotilde Mannoury la Cour et al.
MOLECULAR PHARMACOLOGY (2006)
Whole genome expression profiling of glucose-dependent insulinotropic peptide (GIP)- and adrenocorticotropin-dependent adrenal hyperplasias reveals novel targets for the study of GIP-dependent Cushing's syndrome
Antoine Lampron et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2006)
Human trabecular meshwork cells express functional serotonin-2A (5HT2A) receptors:: Role in IOP reduction
Najam A. Sharif et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2006)
Serotonin transport and serotonin transporter-mediated antidepressant recognition are controlled by 5-HT2B receptor signaling in serotonergic neuronal cells
Jean-Marie Launay et al.
FASEB JOURNAL (2006)
Increased 5-HT2A receptor binding in euthymic, medication-free patients recovered from depression:: A positron emission study with [11C] MDL 100,907
Zubin Bhagwagar et al.
AMERICAN JOURNAL OF PSYCHIATRY (2006)
Intracellular 5-HT2C-receptor dephosphorylation:: a new target for treating drug addiction
Christian P. Mueller et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2006)
The 5-HT4 antagonist R216073 does not affect gastric motor and sensory function in patients with functional dyspepsia
N. Van Lelyveld et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2006)
A null mutation of the serotonin 6 receptor alters acute responses to ethanol
Stephen J. Bonasera et al.
NEUROPSYCHOPHARMACOLOGY (2006)
Efficacy of selective 5-HT6 receptor ligands determined by monitoring 5-HT6 receptor-mediated cAMP signaling pathways
Gonzalo Romero et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Higher 5-HTIA receptor binding potential during a major depressive episode predicts poor treatment response:: Preliminary data from a naturalistic study
Rarnin V. Parsey et al.
NEUROPSYCHOPHARMACOLOGY (2006)
Hallucinogen-induced UP states in the brain slice of rat-prefrontal cortex: Role of glutamate spillover and NR2B-NMDA receptors
Evelyn K. Lambe et al.
NEUROPSYCHOPHARMACOLOGY (2006)
Endogenous 5-HT2B receptor activation regulates neonatal respiratory activity in vitro
Silke Guenther et al.
JOURNAL OF NEUROBIOLOGY (2006)
5-HT2A receptor induces ERK phosphorylation and proliferation through ADAM-17 tumor necrosis factor-α-converting enzyme (TACE) activation and heparin-bound epidermal growth factor-like growth factor (HB-EGF) shedding in mesangial cells
Monika Gooz et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Cortical 5-HT2A receptor signaling modulates anxiety-like behaviors in mice
Noelia V. Weisstaub et al.
SCIENCE (2006)
Serotonin reciprocally regulates melanocortin neurons to modulate food intake
Lora K. Heisler et al.
NEURON (2006)
5-HT1A receptor agonist-mediated protection from MPTP toxicity in mouse and macaque models of Parkinson's disease
Erwan Bezard et al.
NEUROBIOLOGY OF DISEASE (2006)
A neurotrophic model for stress-related mood disorders
Ronald S. Duman et al.
BIOLOGICAL PSYCHIATRY (2006)
Differential effects of 5-hydroxytryptamine4 receptor agonists at gastric versus cardiac receptors:: An operational framework to explain and quantify organ-specific behavior
Joris H. De Maeyer et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Pharmacological evidence for a functional serotonin-2B receptor in a human uterine smooth muscle cell line
CR Kelly et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
Transgenic mice overexpressing the 5-hydroxytryptamine transporter gene in smooth muscle develop pulmonary hypertension
Christophe Guignabert et al.
CIRCULATION RESEARCH (2006)
Molecular cloning and pharmacological characterization of serotonin 5-HT3A receptor subtype in dog
Thomas N. Jensen et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
The effect of atypical and classical antipsychotics on sub-chronic PCP-induced cognitive deficits in a reversal-learning paradigm
Z Abdul-Monim et al.
BEHAVIOURAL BRAIN RESEARCH (2006)
The contractile effect of the ghrelin receptor antagonist, D-Lys3-Ghrp-6, in rat fundic strips is mediated through 5-HT receptors
I Depoortere et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Investigation of the SSRI augmentation properties of 5-HT2 receptor antagonists using in vivo microdialysis
LJ Boothman et al.
NEUROPHARMACOLOGY (2006)
Pharmacological and behavioral profile of N-(4-fluorophenylmethyl)-N-(1-methylpiperidin-4-yl)-N′-(4-(2-methylpropyloxy)phenylmethyl) carbamide (2R, 3R)-dihydroxybutanedioate (2:1) (ACP-103), a novel 5-hydroxytryptamine2A receptor inverse agonist
KE Vanover et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
The acute and chronic administration of (±)-8-hydroxy-2-(Di-n-propylamino) tetralin significantly alters the activity of spontaneously active midbrain dopamine neurons in rats:: An in vivo electrophysiological study
K Nakarura et al.
SYNAPSE (2006)
Multi-target strategies for the improved treatment of depressive states: Conceptual foundations and neuronal substrates, drug discovery and therapeutic application
MJ Millan
PHARMACOLOGY & THERAPEUTICS (2006)
Stepwise control of osteogenic differentiation by 5-HT2B receptor signaling:: Nitric oxide production and phospholipase A2 activation
M Locker et al.
CELLULAR SIGNALLING (2006)
Evidence for a vagal pathophysiology for bulimia nervosa and the accompanying depressive symptoms
Patricia L. Faris et al.
JOURNAL OF AFFECTIVE DISORDERS (2006)
Serotonin 5-HT2A and 5-HT6 receptors in the prefrontal cortex of Alzheimer and normal aging patients
Dietrich E. Lorke et al.
BMC NEUROSCIENCE (2006)
Distinct β-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation
D Gesty-Palmer et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2006)
Serotonin inhibits voltage-gated K+ currents in pulmonary artery smooth muscle cells -: Role of 5-HT2A receptors, caveolin-1, and KV1.5 channel internalization
A Cogolludo et al.
CIRCULATION RESEARCH (2006)
Effect of serotonin receptor 2 blockage on liver regeneration after partial hepatectomy in the rat liver
GK Papadimas et al.
LIVER INTERNATIONAL (2006)
Functional bowel disorders
George F. Longstreth et al.
GASTROENTEROLOGY (2006)
p90 ribosomal S6 kinase 2 exerts a tonic brake on G protein-coupled receptor signaling
DJ Sheffler et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Relationship of disinhibition and aggression to blunted prolactin response to meta-chlorophenylpiperazine in cocaine-dependent patients
AA Patkar et al.
PSYCHOPHARMACOLOGY (2006)
Oncogenic property of acrogranin in human uterine leiomyosarcoma:: Direct evidence of genetic contribution in vivo tumorigenesis
N Matsumura et al.
CLINICAL CANCER RESEARCH (2006)
Disruption of PTEN coupling with 5-HT2C receptors suppresses behavioral responses induced by drugs of abuse
SP Ji et al.
NATURE MEDICINE (2006)
Serotonin 1B and 2C receptor interactions in the modulation of feeding behaviour in the mouse
GL Dalton et al.
PSYCHOPHARMACOLOGY (2006)
Effects of the 5-HT7 receptor antagonist SB-269970 microinjected into the dorsal raphe nucleus on REM sleep in the rat
JM Monti et al.
BEHAVIOURAL BRAIN RESEARCH (2006)
Heterologous desensitization is evoked by both agonist and antagonist stimulation of the human 5-HT7 serotonin receptor
KA Krobert et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Evidence for the preferential involvement of 5-HT2A serotonin receptors in stress- and drug-induced dopamine release in the rat medial prefrontal cortex
EA Pehek et al.
NEUROPSYCHOPHARMACOLOGY (2006)
A novel form of immune signaling revealed by transmission of the inflammatory mediator serotonin between dendritic cells and T cells
PJ O'Connell et al.
BLOOD (2006)
5-Hydroxytryptamine 1A receptor blockade facilitates aversive learning in mice:: Interactions with cholinergic and glutamatergic mechanisms
N Madjid et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2006)
The effect of 5-hydroxtryptamine on the regulation of megakaryocytopoiesis
YS Liu et al.
HEMATOLOGY (2006)
Pindolol augmentation of antidepressant response
F Artigas et al.
CURRENT DRUG TARGETS (2006)
Monoamine receptors in human corneal epithelium and endothelium
M Grueb et al.
ACTA OPHTHALMOLOGICA SCANDINAVICA (2006)
The snoRNA HBII-52 regulates alternative splicing of the serotonin receptor 2C
S Kishore et al.
SCIENCE (2006)
Alterations in 5-HT1B receptor function by p11 in depression-like states
P Svenningsson et al.
SCIENCE (2006)
Co-ordinated covalent modification of G-protein coupled receptors
Ignacio Torrecilla et al.
CURRENT PHARMACEUTICAL DESIGN (2006)
Donitriptan, but not sumatriptan, inhibits capsaicin-induced canine external carotid vasodilatation via 5-HT1B rather than 5-HT1D receptors
E. Munoz-Islas et al.
BRITISH JOURNAL OF PHARMACOLOGY (2006)
Activation of adenylyl cyclase by endogenous G(s)-coupled receptors in human embryonic kidney 293 cells is attenuated by 5-HT7 receptor expression
KW Andressen et al.
MOLECULAR PHARMACOLOGY (2006)
Expression mapping of 5-HT1 serotonin receptor subtypes during fetal and early postnatal mouse forebrain development
A. Bonnin et al.
NEUROSCIENCE (2006)
Characterization of 5-HT3 receptor mutations identified in schizophrenic patients
Andrew J. Thompson et al.
JOURNAL OF MOLECULAR NEUROSCIENCE (2006)
Serotonin 5-HT2A and 5-HT2C receptors as potential targets for modulation of psychostimulant use and dependence
Marcy J. Bubar et al.
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2006)
5-ht(5A) receptors as a therapeutic target
David R. Thomas
PHARMACOLOGY & THERAPEUTICS (2006)
5-Hydroxytryptamine receptors in the human cardiovascular system
Alberto J. Kaumann et al.
PHARMACOLOGY & THERAPEUTICS (2006)
SB-699551-A (3-cyclopentyl-N-[2-(dimethylamino) ethyl]-N-[(4'-{[2-phenylethyl)amino]methyl}-4-biphenylyl) methyl]propanamide dihydrochloride), a novel 5-ht(54) receptor-selective antagonist, enhances 5-HT neuronal function: Evidence for an autoreceptor role for the 5-Ht(5A) receptor in guinea pig brain
David R. Thomas et al.
NEUROPHARMACOLOGY (2006)
Effect of the selective 5-HT7 receptor antagonist SB 269970 in animal models of anxiety and depression
Anna Wesolowska et al.
NEUROPHARMACOLOGY (2006)
Distribution of mRNA coding for 5-hydroxytryptamine receptor subtypes in the intestines of healthy dairy cows and dairy cows with cecal dilatation-dislocation
L Engel et al.
AMERICAN JOURNAL OF VETERINARY RESEARCH (2006)
Excitatory effects of serotonin on rat striatal cholinergic interneurones
C Blomeley et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Contribution of 5-HT2 receptor subtypes to sleep-wakefulness and respiratory control, and functional adaptations in knock-out mice lacking 5-HT2A receptors
D Popa et al.
JOURNAL OF NEUROSCIENCE (2005)
Inhibition of serotonin 5-hydroxytryptamine2C receptor function through heterodimerization - Receptor dimers bind two molecules of ligand and one G-protein
K Herrick-Davis et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
5-Hydroxytryptamine induced excitation and inhibition in the subthalamic nucleus:: Action at 5-HT2C, 5-HT4 and 5-HT1A receptors
IM Stanford et al.
NEUROPHARMACOLOGY (2005)
Effects of novel antipsychotics with mixed D2 antagonist/5-HT1A agonist properties on PCP-induced social interaction deficits in the rat
LAB Slot et al.
NEUROPHARMACOLOGY (2005)
5-HT6 receptors:: a novel target for cognitive enhancement
ES Mitchell et al.
PHARMACOLOGY & THERAPEUTICS (2005)
The selective 5-HT2A receptor antagonist M100907 enhances antidepressant-like behavioral effects of the SSRI fluoxetine
GJ Marek et al.
NEUROPSYCHOPHARMACOLOGY (2005)
Expression and function of 5-HT4 receptors in the mouse enteric nervous system
M Liu et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2005)
The selective 5-HT6 receptor antagonist Ro4368554 restores memory performance in cholinergic and serotonergic models of memory deficiency in the rat
CKJ Lieben et al.
NEUROPSYCHOPHARMACOLOGY (2005)
Roles of extracellular signal-regulated kinase and Akt signaling in coordinating nuclear transcription factor-κB-dependent cell survival after serotonin 1A receptor activation
SC Hsiung et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Aqueous humor dynamics in monkeys after topical R-DOI
BT Gabelt et al.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE (2005)
Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes
C de Luca et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Expression profile of serotonin4 (5-HT4) receptors in adrenocortical aldosterone-producing adenomas
D Cartier et al.
EUROPEAN JOURNAL OF ENDOCRINOLOGY (2005)
5-HT7 receptor inhibition and inactivation induce antidepressantlike behavior and sleep pattern
PB Hedlund et al.
BIOLOGICAL PSYCHIATRY (2005)
5-HT7 receptors modulate peristalsis and accommodation in the guinea pig ileum
M Tonini et al.
GASTROENTEROLOGY (2005)
General anesthetic-induced channel gating enhancement of 5-hydroxytryptamine type 3 receptors depends on receptor subunit composition
K Solt et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Molecular determinants of single-channel conductance and ion selectivity in the Cys-loop family:: insights from the 5-HT3 receptor
JA Peters et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2005)
Decision making, impulse control and loss of willpower to resist drugs: a neurocognitive perspective
A Bechara
NATURE NEUROSCIENCE (2005)
CCK and 5-HT act synergistically to suppress food intake through simultaneous activation of CCK-1 and 5-HT3 receptors
MR Hayes et al.
PEPTIDES (2005)
Pathways modulating neural KCNQ/M (Kv7) potassium channels
P Delmas et al.
NATURE REVIEWS NEUROSCIENCE (2005)
5-HT1A receptor-mediated G protein activation assessed by [35S]GTPγS binding in rat cerebral cortex
Y Odagaki et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2005)
Serotonin 5-HT2C receptor agonists:: For the treatment of obesity
KJ Miller
MOLECULAR INTERVENTIONS (2005)
2-Alkyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indoles as novel 5-HT6 receptor agonists
C Mattsson et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Differential effects of the 5-hydroxytryptamine (5-HT)1A receptor inverse agonists Rec 27/0224 and Rec 27/0074 on electrophysiological responses to 5-HT1A receptor activation in rat dorsal raphe nucleus and hippocampus in vitro
R Corradetti et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Pre- and postsynaptic localization of the 5-HT7 receptor in rat dorsal spinal cord:: Immunocytochemical evidence
S Doly et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2005)
Discovery of a potent and selective 5-ht5A receptor antagonist by high-throughput chemistry
DF Corbett et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2005)
Absence of Fyn and Src causes a reeler-like phenotype
G Kuo et al.
JOURNAL OF NEUROSCIENCE (2005)
Interaction of calmodulin with the serotonin 5-hydroxytryptamine2A receptor -: A putative regulator of G protein coupling and receptor phosphorylation by protein kinase C
JH Turner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Serotonin 5-HT2C receptors as a target for the treatment of depressive and anxious states:: Focus on novel therapeutic strategies
MJ Millan
THERAPIE (2005)
Novel antipsychotics activate recombinant human and native rat serotonin 5-HT1A receptors:: affinity, efficacy and potential implications for treatment of schizophrenia
A Newman-Tancredi et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2005)
Pronociceptive role of peripheral and spinal 5-HT7 receptors in the formalin test
HI Rocha-González et al.
PAIN (2005)
Atomic force microscopy reveals the stoichiometry and subunit arrangement of 5-HT3 receptors
NP Barrera et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
5-HT7 receptor is coupled to Gα subunits of heterotrimeric G12-protein to regulate gene transcription and neuronal morphology
E Kvachnina et al.
JOURNAL OF NEUROSCIENCE (2005)
Dual serotonergic regulation of ventricular contractile force through 5-HT2A and 5-HT4 receptors induced in the acute failing heart
E Qvigstad et al.
CIRCULATION RESEARCH (2005)
SSR181507, a dopamine D2 receptor antagonist and 5-HT1A receptor agonist, alleviates disturbances of novelty discrimination in a social context in rats, a putative model of selective attention deficit
JP Terranova et al.
PSYCHOPHARMACOLOGY (2005)
The neural basis of addiction: A pathology of motivation and choice
PW Kalivas et al.
AMERICAN JOURNAL OF PSYCHIATRY (2005)
Uncoupling and endocytosis of 5-hydroxytryptamine 4 receptors - Distinct molecular events with different GRK2 requirements
G Barthet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Dual role of the RIC-3 protein in trafficking of serotonin and nicotinic acetylcholine receptors
M Castillo et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Gain modulation by serotonin in pyramidal neurones of the rat prefrontal cortex
ZW Zhang et al.
JOURNAL OF PHYSIOLOGY-LONDON (2005)
Modulation of human 5-hydroxytryptamine type 3AB receptors by volatile anesthetics and n-alcohols
R Stevens et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
The role of 5-HT2C receptor polymorphisms in the pharmacogenetics of antipsychotic drug treatment
GP Reynolds et al.
PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY (2005)
Activation of 5-hydroxytryptamine 1A receptors suppresses the cardiovascular response evoked from the dorsomedial hypothalamic nucleus
J Horiuchi et al.
HYPERTENSION (2005)
Cell surface expression of 5-hydroxytryptamine type 3 receptors is promoted by RIC-3
AX Cheng et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
An expression screen reveals modulators of class II histone deacetylase phosphorylation
SR Chang et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Characterization of serotonin 5-HT2C receptor signaling to extracellular signal-regulated kinases 1 and 2
TD Werry et al.
JOURNAL OF NEUROCHEMISTRY (2005)
5-HT2A/2C receptor signaling via phospholipase A2 and arachidonic acid is attenuated in mice lacking the serotonin reuptake transporter
Y Qu et al.
PSYCHOPHARMACOLOGY (2005)
Prucalopride is a partial agonist through human and porcine atrial 5-HT4 receptors:: comparison with recombinant human 5-HT4 splice variants
KA Krobert et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2005)
Differential agonist-mediated internalization of the human 5-hydroxytryptamine 7 receptor isoforms
CR Guthrie et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
Expression of serotonin receptors 2B and 4 in human prostate cancer tissue and effects of their antagonists on prostate cancer cell lines
N Dizeyi et al.
EUROPEAN UROLOGY (2005)
5-HTM-mediated serotonin signaling is required for eye morphogenesis in Xenopus
S De Lucchini et al.
MOLECULAR AND CELLULAR NEUROSCIENCE (2005)
Serotonin transporter inhibition prevents and reverses monocrotaline-induced pulmonary hypertension in rats
C Guignabert et al.
CIRCULATION (2005)
Serotonin alterations, in anorexia and bulimia nervosa: New insights from imaging studies
WH Kaye et al.
PHYSIOLOGY & BEHAVIOR (2005)
Clozapine, ziprasidone and aripiprazole but not haloperidol protect against kainic acid-induced lesion of the striatum in mice, in vivo:: Role of 5-HT1A receptor activation
C Cosi et al.
BRAIN RESEARCH (2005)
Endogenous expression and protein kinase A-dependent phosphorylation of the guanine nucleotide exchange factor Ras-GRF1 in human embryonic kidney 293 cells
JH Norum et al.
FEBS JOURNAL (2005)
Detailed pharmacological characterization of 5-HT1A-receptor-mediated [35S]GTPγS binding in rat hippocampal membranes
Y Odagaki et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2005)
The serotonin transporter (SLC6A4) is present in B-cell clones of diverse malignant origin: probing a potential antitumor target for psychotropics
EJ Meredith et al.
FASEB JOURNAL (2005)
Serotonin excites neurons in the human submucous plexus via 5-HT3 receptors
K Michel et al.
GASTROENTEROLOGY (2005)
Analysis of the role of 5-HT1A receptors in spatial and aversive learning in the rat
M Lüttgen et al.
NEUROPHARMACOLOGY (2005)
WAY-163909 [(7bR,10aR)-1,2,3,4,8,9,10,10a-octahydro-7bH-cyclopenta-[b][1,4]diazepino[6,7,1hi]indole], a novel 5-hydroxytryptamine 2C receptor-selective agonist with anorectic activity
J Dunlop et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2005)
5-hydroxytryptamine modulates cytokine and chemokine production in LPS-primed human monocytes via stimulation of different 5-HTR subtypes
T Dürk et al.
INTERNATIONAL IMMUNOLOGY (2005)
Modifications of 5-HT4 receptor expression in rat brain during memory consolidation
L Manuel-Apolinar et al.
BRAIN RESEARCH (2005)
Frontocortical 5-HT4 receptors exert positive feedback on serotonergic activity:: Viral transfections, subacute and chronic treatments with 5-HT4 agonists
G Lucas et al.
BIOLOGICAL PSYCHIATRY (2005)
Effect of the activation of central 5-HT2C receptors by the 5-HT2C agonist mCPP on blood pressure and heart rate in rats
HS Ferreira et al.
BRAIN RESEARCH (2005)
Inhibitory effects of the 5-HT1A receptor agonist buspirone on stress-induced hyperglycemia in mice:: Involvement of insulin and a buspirone metabolite, 1-(2-pyrimidinyl)piperazine (1-PP)
Y Sugimoto et al.
BIOLOGICAL & PHARMACEUTICAL BULLETIN (2005)
Activation of the JAK/STAT pathway in vascular smooth muscle by serotonin
AKL Banes et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2005)
Neuroprotective efficacy of repinotan HCl, a 5-HT1A receptor agonist, in animal models of stroke and traumatic brain injury
F Mauler et al.
JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM (2005)
Gene expression studies provide clues to the pathogenesis of uterine leiomyoma: new evidence and a systematic review
AA Arslan et al.
HUMAN REPRODUCTION (2005)
Serotonin inhibits Na+/H+ exchange activity via 5-HT4 receptors and activation of PKCα in human intestinal epithelial cells
RK Gill et al.
GASTROENTEROLOGY (2005)
The natural mutation encoding a C terminus-truncated 5-hydroxytryptamine2B receptor is a gain of proliferative functions
M Deraet et al.
MOLECULAR PHARMACOLOGY (2005)
5-hydroxytryptamine synthesis in HL-1 cells and neonatal rat cardiocytes
K Ikeda et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2005)
[H3]LY334370, a novel radioligand for the 5-HT1F receptor.: I.: In vitro characterization of binding properties
DB Wainscott et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2005)
Expression of serotonin 5-HT2c receptors in GABAergic cells of the anterior raphe nuclei
J Serrats et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2005)
Appearance of a ventricular 5-HT4 receptor-mediated inotropic response to serotonin in heart failure
E Qvigstad et al.
CARDIOVASCULAR RESEARCH (2005)
Toward transcriptional therapies for the failing heart: chemical screens to modulate genes
TA McKinsey et al.
JOURNAL OF CLINICAL INVESTIGATION (2005)
Vagal control of the heart: central serotonergic (5-HT) mechanisms
D Jordan
EXPERIMENTAL PHYSIOLOGY (2005)
Genetic knockout and pharmacological blockade studies of the 5-HT7 receptor suggest therapeutic potential in depression
M Guscott et al.
NEUROPHARMACOLOGY (2005)
Low gene expression conferred by association of an allele of the 5-HT2C receptor gene with antipsychotic-induced weight gain
PR Buckland et al.
AMERICAN JOURNAL OF PSYCHIATRY (2005)
Emerging role of homo- and heterodimerization in G-protein-coupled receptor biosynthesis and maturation
S Bulenger et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2005)
Changes of 5-HT receptor subtype mRNAs in rat dorsal root ganglion by bee venom-induced inflammatory pain
XY Liu et al.
NEUROSCIENCE LETTERS (2005)
Sorting nexins - Unifying trends and new perspectives
J Carlton et al.
TRAFFIC (2005)
Anxiolytic properties of agomelatine, an antidepressant with melatoninergic and serotonergic properties:: role of 5-HT2C receptor blockade
MJ Millan et al.
PSYCHOPHARMACOLOGY (2005)
A TASK-like pH- and amine-sensitive 'leak' K+ conductance regulates neonatal rat facial motoneuron excitability in vitro
PM Larkman et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Pharmacological properties of the Cys23Ser single nucleotide polymorphism in human 5-HT2C receptor isoforms
HM Fentress et al.
PHARMACOGENOMICS JOURNAL (2005)
The olfactory bulbectomised rat as a model of depression
C Song et al.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS (2005)
Serotonergic 5-HT2C receptors as a potential therapeutic target for the design antiepileptic drugs
M Isaac
CURRENT TOPICS IN MEDICINAL CHEMISTRY (2005)
Is there a pharmacological basis for differences in 5-HT3-receptor antagonist efficacy in refractory patients?
R de Wit et al.
CANCER CHEMOTHERAPY AND PHARMACOLOGY (2005)
The novel analgesic and high-efficacy 5-HT1A receptor agonist F 13640 inhibits nociceptive responses, wind-up, and after-discharges in spinal neurons and withdrawal reflexes
HJ You et al.
EXPERIMENTAL NEUROLOGY (2005)
NMDA-induced potentiation of mGluR5 is mediated by activation of protein phosphatase 2B/calcineurin
S Alagarsamy et al.
NEUROPHARMACOLOGY (2005)
A rapid new assay to detect RNA editing reveals antipsychotic-induced changes in serotonin-2C transcripts
MSK Sodhi et al.
MOLECULAR PHARMACOLOGY (2005)
Serotonergic regulation of calcium-activated potassium currents in rodent prefrontal cortex
C Villalobos et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2005)
Slow excitatory post-synaptic potentials in myenteric AH neurons of the guinea-pig ileum are reduced by the 5-hydroxytrytamine(7) receptor antagonist SB 269970
RL Monro et al.
NEUROSCIENCE (2005)
Evidence for 5-HT2B and 5-HT7 receptor-mediated relaxation in pulmonary arteries of weaned pigs
S Jahnichen et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2005)
Different properties of the central and peripheral forms of human tryptophan hydroxylase
J McKinney et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Enhanced activation of Akt and extracellular-regulated kinase pathways by simultaneous occupancy of G(q)-coupled 5-HT2A receptors and G(s)-coupled 5-HT7A receptors in PC12 cells
NN Johnson-Farley et al.
JOURNAL OF NEUROCHEMISTRY (2005)
Investigation of the association between 5-HT3A receptor gene polymorphisms and efficiency of antiemetic treatment with 5-HT3 receptor antagonists
R Kaiser et al.
PHARMACOGENETICS (2004)
Altered RNA editing of serotonin 5-HT2C receptor induced by interferon:: implications for depression associated with cytokine therapy
WD Yang et al.
MOLECULAR BRAIN RESEARCH (2004)
Calmodulin interacts with the third intracellular loop of the serotonin 5-hydroxytryptamine1A receptor at two distinct sites -: Putative role in receptor phosphorylation by protein kinase C
JH Turner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Selective 5-HT1A and 5-HT7 antagonists decrease epileptic activity in the WAG/Rij rat model of absence epilepsy
M Graf et al.
NEUROSCIENCE LETTERS (2004)
Functional 5-HT receptors in human occipital artery
R Verheggen et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2004)
Mice lacking 5-HT7 receptors show specific impairments in contextual learning
AJ Roberts et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2004)
A 5-HT2C receptor promoter polymorphism (HTR2C-759C/T) is associated with obesity in women, and with resistance to weight loss in heterozygotes
EC Pooley et al.
AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS (2004)
A paracrine signaling role for serotonin in rat taste buds: expression and localization of serotonin receptor subtypes
N Kaya et al.
AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY (2004)
Evidence that RNA editing modulates splice site selection in the 5-HT2C receptor gene
R Flomen et al.
NUCLEIC ACIDS RESEARCH (2004)
8-OH-DPAT acts on both 5-HT1A and 5-HT7 receptors to induce hypothermia in rodents
PB Hedlund et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Phosphorylation of tau by fyn: Implications for Alzheimer's disease
G Lee et al.
JOURNAL OF NEUROSCIENCE (2004)
A small molecular activator of cardiac hypertrophy uncovered in a chemical screen for modifiers of the calcineurin signaling pathway
E Bush et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Kv1.1 and Kv1.3 channels contribute to the delayed-rectifying K+ conductance in rat choroid plexus epithelial cells
T Speake et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2004)
Multicenter, open-label, trial of sarizotan in Parkinson disease patients with levodopa-induced dyskinesias (the SPLENDID study)
CW Olanow et al.
CLINICAL NEUROPHARMACOLOGY (2004)
Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1
JC Hartner et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene
QD Wang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
5-ht5B receptor mRNA in the raphe nuclei:: Coexpression with serotonin transporter
J Serrats et al.
SYNAPSE (2004)
Further characterization of the 5-HT1 receptors mediating cardiac sympatho-inhibition in pithed rats:: pharmacological correlation with the 5-HT1B and 5-HT1D subtypes
A Sánchez-López et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2004)
In vivo evidence that 5-HT2C receptor antagonist but not agonist modulates cocaine-induced dopamine outflow in the rat nucleus accumbens and striatum
S Navailles et al.
NEUROPSYCHOPHARMACOLOGY (2004)
Injection of the 5-HT2C receptor agonist Ro60-0175 into the ventral tegmental area reduces cocaine-induced locomotor activity and cocaine self-administration
PJ Fletcher et al.
NEUROPSYCHOPHARMACOLOGY (2004)
Molecular cloning and pharmacological characterization of the guinea pig 5-HT1E receptor
F Bai et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
RNA editing induces variation in desensitization and trafficking of 5-hydroxytryptamine 2c receptor isoforms
S Marion et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Cdk5 phosphorylation of doublecortin ser297 regulates its effect on neuronal migration
T Tanaka et al.
NEURON (2004)
Attenuated response to stress and novelty and hypersensitivity to seizures in 5-HT4 receptor knock-out mice
V Compan et al.
JOURNAL OF NEUROSCIENCE (2004)
Substituted furo[3,2-b]pyridines:: novel bioisosteres of 5-HT1F receptor agonists
BM Mathes et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Mechanisms intrinsic to 5-HT2B receptor-induced potentiation of NMDA receptor responses in frog motoneurones
AM Holohean et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Pharmacology of serotonin: What a clinician should know
F De Ponti
GUT (2004)
Inactivation of 5-HT2C receptors potentiates consequences of serotonin reuptake blockade
TIFH Cremers et al.
NEUROPSYCHOPHARMACOLOGY (2004)
Cutting edge: Serotonin is a chemotactic factor for eosinophils and functions additively with eotaxin
SA Boehme et al.
JOURNAL OF IMMUNOLOGY (2004)
Regulation of serotonin 5-HT2C receptors by chronic ligand exposure
MG Devlin et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Distribution of 5-HT7 receptors in the human brain:: a preliminary autoradiographic study using [3H]SB-269970
K Varnäs et al.
NEUROSCIENCE LETTERS (2004)
Lack of association between the-759C/T polymorphism of the 5-HT2C receptor gene and clozapine-induced weight gain among German schizophrenic individuals
FM Theisen et al.
PSYCHIATRIC GENETICS (2004)
Ligand dependency of 5-hydroxytryptamine 2C receptor internalization
BD Schlag et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
A positron emission tomography study of the 5-HT1A receptor in schizophrenia and during clozapine treatment
RA Bantick et al.
JOURNAL OF PSYCHOPHARMACOLOGY (2004)
Functional serotonin 5-HT4 receptors in porcine and human ventricular myocardium with increased 5-HT4 mRNA in heart failure
T Brattelid et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2004)
5-HT5A receptor localization in the rat spinal cord suggests a role in nociception and control of pelvic floor musculature
S Doly et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2004)
Involvement of the serotonin 5-HT2B receptor in cardiac hypertrophy linked to sympathetic stimulation control of interleukin-6, interleukin-1β, and tumor necrosis factor-α cytokine production by ventricular fibroblasts
F Jaffré et al.
CIRCULATION (2004)
Three putative N-glycosylation sites within the murine 5-HT3A-receptor sequence affect plasma membrane targeting, ligand binding, and calcium influx in heterologous mammalian cells
PL Quirk et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2004)
Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Gαq-coupled protein receptors
A Bhatnagar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
In vivo regulation of glycogen synthase kinase-3β (GSK3β) by serotonergic activity in mouse brain
XH Li et al.
NEUROPSYCHOPHARMACOLOGY (2004)
Gene expression profiles during human CD4+ T cell differentiation
MS Lee et al.
INTERNATIONAL IMMUNOLOGY (2004)
Pharmacological characterisation of the agonist radioligand binding site of 5-HT2A, 5-HT2B and 5-HT2C receptors
AR Knight et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2004)
Increased wakefulness, motor activity and decreased theta activity after blockade of the 5-HT2B receptor by the subtype-selective antagonist SB-215505
S Kantor et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
The 5HT1A receptor agonist, 8-OH-DPAT, protects neurons and reduces astroglial reaction after ischemic damage caused by cortical devascularization
AJ Ramos et al.
BRAIN RESEARCH (2004)
Design, synthesis and evaluation of bicyclic benzamides as novel 5-HT1F receptor agonists
DY Zhang et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2004)
Effects of the 5-HT7 receptor antagonists SB-269970 and DR 4004 in autoshaping Pavlovian/instrumental learning task
A Meneses
BEHAVIOURAL BRAIN RESEARCH (2004)
Hippocampal 5-hydroxytryptamine receptors: abnormalities in postmortem brain from schizophrenic subjects
E Scarr et al.
SCHIZOPHRENIA RESEARCH (2004)
5-HT1B receptors, α2A/2C- and, to a lesser extent, α1-adrenoceptors mediate the external carotid vasoconstriction to ergotamine in vagosympathectomised dogs
LF Valdivia et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2004)
Mpdz is a quantitative trait gene for drug withdrawal seizures
RL Shirley et al.
NATURE NEUROSCIENCE (2004)
The human serotonin receptor 213: coding region polymorphisms and association with vulnerability to illegal drug abuse
ZC Lin et al.
PHARMACOGENETICS (2004)
Association of the C(-1019)G 5-HT1A functional promoter polymorphism with antidepressant response
S Lemonde et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2004)
Focus on the 5-HT1A receptor: emerging role of a gene regulatory variant in psychopathology and pharmacogenetics
KP Lesch et al.
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY (2004)
Subchronic effects of olanzapine on sleep EEG in schizophrenic patients with predominantly negative symptoms
MJ Müller et al.
PHARMACOPSYCHIATRY (2004)
Involvement of 5-HT1B receptors in triptan-induced contractile responses in guinea-pig isolated iliac artery
S Jähnichen et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2004)
5-HT1A receptors are differentially involved in the anxiolytic- and antidepressant-like effects of 8-OH-DPAT and fluoxetine in the rat
J De Vry et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2004)
8-OH-DPAT as a 5-HT7 agonist: phase shifts of the circadian biological clock through increases in cAMP production
J Sprouse et al.
NEUROPHARMACOLOGY (2004)
The human polyomavirus, JCV, uses serotonin receptors to infect cells
GF Elphick et al.
SCIENCE (2004)
Family-based association studies between 5-HT5A receptor gene and schizophrenia
C Dubertret et al.
JOURNAL OF PSYCHIATRIC RESEARCH (2004)
β-oxygenated analogues of the 5-HT2A serotonin receptor agonist 1-(4-bromo-2,5-dimethoxyphenyl)-2-aminopropane
RA Glennon et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Autoradiographic distribution of 5-HT7 receptors in the human brain using [H-3]mesulergine: comparison to other mammalian species
FJ Martin-Cora et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
RNA editing of the human serotonin 5-HT2C receptor disrupts transactivation of the small G-protein RhoA
L McGrew et al.
MOLECULAR PHARMACOLOGY (2004)
Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid receptors
JD Leggett et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Cloning and pharmacological characterisation of the guinea pig 5-ht5A receptor
DR Thomas et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Biochemical and biophysical characterization of serotonin 5-HT2C receptor homodimers on the plasma membrane of living cells
K Herrick-Davis et al.
BIOCHEMISTRY (2004)
Uropathic observations in mice expressing a constitutively active point mutation in the 5-HT3A receptor subunit
A Bhattacharya et al.
JOURNAL OF NEUROSCIENCE (2004)
5-HT2A and 5-HT2C receptor antagonists have opposing effects on a measure of impulsivity:: interactions with global 5-HT depletion
CA Winstanley et al.
PSYCHOPHARMACOLOGY (2004)
Region specific changes in forebrain 5-hydroxytryptamine(1A) and 5-hydroxytryptamine(2A) receptors in isolation-reared rats: An in vitro autoradiography study
MA Preece et al.
NEUROSCIENCE (2004)
Prevalence of neuroleptic-induced movement disorders in chronic schizophrenia inpatients
S Janno et al.
AMERICAN JOURNAL OF PSYCHIATRY (2004)
SSR181507, a putative atypical antipsychotic with dopamine D2 antagonist and 5-HT1A agonist activities:: improvement of social interaction deficits induced by phencyclidine in rats
D Boulay et al.
NEUROPHARMACOLOGY (2004)
Proximity between 5-HT secreting enteroendocrine cells and lymphocytes in the gut mucosa of rhesus macaques (Macaca mulatta) is suggestive of a role for enterochrornaffin cell 5-HT in mucosal immunity
GB Yang et al.
JOURNAL OF NEUROIMMUNOLOGY (2004)
The 5-HT4 receptor agonist, tegaserod, is a potent 5-HT2B receptor antagonist in vitro and in vivo
DT Beattie et al.
BRITISH JOURNAL OF PHARMACOLOGY (2004)
Identification and importance of N-glycosylation of the human 5-hydroxytryptamine3A receptor subunit
SA Monk et al.
BIOCHEMICAL PHARMACOLOGY (2004)
GABAergic modulation of 5-HT7 receptor-mediated effects on 5-HT efflux in the guinea-pig dorsal raphe nucleus
C Roberts et al.
NEUROPHARMACOLOGY (2004)
The serotonin transporter is present and functional in peripheral arterial smooth muscle
W Ni et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2004)
5-ht(6) Receptors
Marie L. Woolley et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2004)
Early-life blockade of the 5-HT transporter alters emotional behavior in adult mice
MS Ansorge et al.
SCIENCE (2004)
5-HT7 Receptors
David R. Thomas et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2004)
TRPV1 function in mouse colon sensory neurons is enhanced by metabotropic 5-hydroxytryptamine receptor activation
T Sugiura et al.
JOURNAL OF NEUROSCIENCE (2004)
Severe multivalvular heart disease: A new complication of the ergot derivative dopamine agonists
J Horvath et al.
MOVEMENT DISORDERS (2004)
Expression of genes coding melatonin and serotonin receptors in rodent skin
A Slominski et al.
BIOCHIMICA ET BIOPHYSICA ACTA-GENE STRUCTURE AND EXPRESSION (2004)
Increased 5-HT2A receptor expression and function following central glucocorticoid receptor knockdown in vivo
A Islam et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2004)
Mutational analysis of the serotonin receptor 5HT2c in severe early-onset human obesity
WT Gibson et al.
CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY (2004)
New sorting nexin (SNX27) and NHERF specifically interact with the 5-HT4(a) receptor splice variant:: roles in receptor targeting
L Joubert et al.
JOURNAL OF CELL SCIENCE (2004)
5-HT4 Receptors
J. Bockaert et al.
CNS & NEUROLOGICAL DISORDERS-DRUG TARGETS (2004)
Cloning, pharmacological characterisation and tissue distribution of a novel 5-HT4 receptor splice variant, 5-HT4(i)
T Brattelid et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2004)
Dynamics of β2-adrenergic receptor -: Ligand complexes on living cells
O Hegener et al.
BIOCHEMISTRY (2004)
Hippocampal long-term depression and long-term potentiation encode different aspects of novelty acquisition
A Kemp et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
RNA editing and short variant of serotonin 2C receptor mRNA in neuronally differentiated NG108-15 cells
M Tohda et al.
JOURNAL OF PHARMACOLOGICAL SCIENCES (2004)
Role of tension receptors in dryspeptic patients with hypersensitivity to gastric distention
J Tack et al.
GASTROENTEROLOGY (2004)
The serotoninergic receptors of human dendritic cells:: Identification and coupling to cytokine release
M Idzko et al.
JOURNAL OF IMMUNOLOGY (2004)
Expression of serotonin receptors and role of serotonin in human prostate cancer tissue and cell lines
N Dizeyi et al.
PROSTATE (2004)
Binding of tryptamine analogs at h5-HT1E receptors:: a structure-affinity investigation
M Dukat et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2004)
Expression of Serotonin1A and Serotonin2A receptors in pyramidal and GABAergic neurons of the rat prefrontal cortex
N Santana et al.
CEREBRAL CORTEX (2004)
The serotonin 5-HT2A and 5-HT2C receptors interact with specific sets of PDZ proteins
C Bécamel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2004)
Expression of 5-HT3A receptors in cells of the immune system
BL Fiebich et al.
SCANDINAVIAN JOURNAL OF RHEUMATOLOGY (2004)
The serotonin1A receptor partial agonist S15535 [4-(benzodioxan-5-yl)1-(indan-2-yl)piperazine] enhances cholinergic transmission and cognitive function in rodents:: A combined neurochemical and behavioral analysis
MJ Millan et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Modification of human 5-HT2C receptor function by Cys23Ser, an abundant, naturally occurring amino-acid substitution
M Okada et al.
MOLECULAR PSYCHIATRY (2004)
Opposing regulation of cell proliferation by retinoic acid and the serotonin2B receptor in the mouse frontonasal mass
N Bhasin et al.
ANATOMY AND EMBRYOLOGY (2004)
5-hydroxytryptamine1B receptor-mediated contraction of rabbit saphenous vein and basilar artery:: Role of vascular endothelium
A Bhattacharya et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2004)
Identification of a novel family of G protein-coupled receptor associated sorting proteins
F Simonin et al.
JOURNAL OF NEUROCHEMISTRY (2004)
N-linked glycosylation of the human bradykinin B-2 receptor is required for optimal cell-surface expression and coupling
S Michineau et al.
BIOLOGICAL CHEMISTRY (2004)
Vasoconstriction in human isolated middle meningeal arteries: determining the contribution of 5-HT1B- and 5-HT1F-receptor activation
Razzaque et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2003)
Structure and Function of the Third Intracellular Loop of the 5-Hydroxytryptamine2A Receptor: The Third Intracellular Loop Is α-Helical and Binds Purified Arrestins
Edward I. Gelber et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Serotonylation of small GTPases is a signal transduction pathway that triggers platelet α-granule release
DJ Walther et al.
CELL (2003)
G-protein-coupled receptors at a glance
WK Kroeze et al.
JOURNAL OF CELL SCIENCE (2003)
Serotonin 2C receptors within the basolateral amygdala induce acute fear-like responses in an open-field environment
BM Campbell et al.
BRAIN RESEARCH (2003)
Serotonin 5-HT2B receptor loss of function mutation in a patient with fenfluramine-associated primary pulmonary hypertension
C Blanpain et al.
CARDIOVASCULAR RESEARCH (2003)
5-HT2C receptors inhibit and 5-HT1A receptors activate the generation of spike-wave discharges in a genetic rat model of absence epilepsy
R Jakus et al.
EXPERIMENTAL NEUROLOGY (2003)
Differences in the central nervous system distribution and pharmacology of the mouse 5-hydroxytryptamine-6 receptor compared with rat and human receptors investigated by radioligand binding, site-directed mutagenesis, and molecular modeling
WD Hirst et al.
MOLECULAR PHARMACOLOGY (2003)
Serotonin receptor antagonist inhibits monocrotaline-induced pulmonary hypertension and prolongs survival in rats
E Hironaka et al.
CARDIOVASCULAR RESEARCH (2003)
Plasticity in serotonin control mechanisms in the gut
MD Gershon
CURRENT OPINION IN PHARMACOLOGY (2003)
SSR181507, a dopamine D2 receptor antagonist and 5-HT1A receptor agonist.: I:: Neurochemical and electrophysiological profile
Y Claustre et al.
NEUROPSYCHOPHARMACOLOGY (2003)
The 5-HT3B subunit confers reduced sensitivity to picrotoxin when co-expressed with the 5-HT3A receptor
P Das et al.
MOLECULAR BRAIN RESEARCH (2003)
What is the role of β-adrenergic signaling in heart failure?
MJ Lohse et al.
CIRCULATION RESEARCH (2003)
SSR181507, a dopamine D2 receptor antagonist and 5-HT1A receptor agonist.: II:: Behavioral profile predictive of an atypical antipsychotic activity
R Depoortere et al.
NEUROPSYCHOPHARMACOLOGY (2003)
Amino acids in transmembrane domain two influence anesthetic enhancement of serotonin-3A receptor function
GF Lopreato et al.
MOLECULAR BRAIN RESEARCH (2003)
Pharmacological profile of the 5-HT-induced inhibition of cardioaccelerator sympathetic outflow in pithed rats:: correlation with 5-HT1 and putative 5-ht5A/5B receptors
A Sánchez-López et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
5-HT1F receptor agonists in acute migraine treatment:: a hypothesis
NM Ramadan et al.
CEPHALALGIA (2003)
Palatability, food intake and the behavioural satiety sequence in male rats
Y Ishii et al.
PHYSIOLOGY & BEHAVIOR (2003)
SER-7b, a constitutively active Gas coupled 5-HT7-like receptor expressed in the Caenorhabditis elegans M4 pharyngeal motorneuron
RJ Hobson et al.
JOURNAL OF NEUROCHEMISTRY (2003)
A single ring of charged amino acids at one end of the pore can control ion selectivity in the 5-HT3 receptor
AJ Thompson et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Agonist actions of dihydroergotamine at 5-HT2B and 5-HT2C receptors and their possible relevance to antimigraine efficacy
B Schaerlinger et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Comparison of hippocampal G protein activation by 5-HT1A receptor agonists and the atypical antipsychotics clozapine and S16924
A Newman-Tancredi et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2003)
The novel melatonin agonist agomelatine (S20098) is an antagonist at 5-hydroxytryptamine2C receptors, blockade of which enhances the activity of frontocortical dopaminergic and adrenergic pathways
MJ Millan et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Improvements in hippocampal-dependent learning and decremental attention in 5-HT3 receptor overexpressing mice
AV Harrell et al.
LEARNING & MEMORY (2003)
Serine 732 phosphorylation of FAK by Cdk5 is important for microtubule organization, nuclear movement, and neuronal migration
ZG Xie et al.
CELL (2003)
Serotonin transporter inhibitors protect against hypoxic pulmonary hypertension
E Marcos et al.
AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE (2003)
RNA editing of serotonin 2C receptor in human postmortem brains of major mental disorders
K Iwamoto et al.
NEUROSCIENCE LETTERS (2003)
Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology
DA Shapiro et al.
NEUROPSYCHOPHARMACOLOGY (2003)
Pharmacological aspects of anticancer drug-induced emesis with emphasis on serotonin release and vagal nerve activity
M Minami et al.
PHARMACOLOGY & THERAPEUTICS (2003)
A complex signaling cascade links the serotonin2A receptor to phospholipase A2 activation:: the involvement of MAP kinases
DM Kurrasch-Orbaugh et al.
JOURNAL OF NEUROCHEMISTRY (2003)
S100B and response to treatment in major depression: a pilot study
V Arolt et al.
EUROPEAN NEUROPSYCHOPHARMACOLOGY (2003)
New lessons from knockout mice: The role of serotonin during development and its possible contribution to the origins of neuropsychiatric disorders
JA Gingrich et al.
CNS SPECTRUMS (2003)
Discriminative stimulus effects of m-chlorophenylpiperazine as a model of the role of serotonin receptors in anxiety
MB Gatch
LIFE SCIENCES (2003)
Cell surface expression of 5-hydroxytryptamine type 3 receptors is controlled by an endoplasmic reticulum retention signal
GW Boyd et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
A cytoplasmic region determines single-channel conductance in 5-HT3 receptors
SP Kelley et al.
NATURE (2003)
5-HT4(a) receptors avert opioid-induced breathing depression without loss of analgesia
T Manzke et al.
SCIENCE (2003)
The 'magic tail' of G protein-coupled receptors: an anchorage for functional protein networks
J Bockaert et al.
FEBS LETTERS (2003)
Novel potent 5-HT1F receptor agonists:: Structure-activity studies of a series of substituted N-[3-(1-methyl-4-piperidinyl)-1H-pyrrolo[3,2-b]pyridin-5-yl]amides
SA Filla et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
Positive allosteric modulator of the human 5-HT2C receptor
W Bin Im et al.
MOLECULAR PHARMACOLOGY (2003)
Functional activity of serotoninergic and melatoninergic systems expressed in the skin
A Slominski et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2003)
Overexpression of the serotonin 5-HT2B receptor in heart leads to abnormal mitochondrial function and cardiac hypertrophy
CG Nebigil et al.
CIRCULATION (2003)
Evaluation of the ocular hypotensive response of serotonin 5-HT1A and 5-HT2 receptor ligands in conscious ocular hypertensive cynomolgus monkeys
JA May et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Convulsive ergotism: epidemics of the serotonin syndrome?
MJ Eadie
LANCET NEUROLOGY (2003)
Structure and gating mechanism of the acetylcholine receptor pore
A Miyazawa et al.
NATURE (2003)
Protective effect of 5-HT1B receptor gene deletion on the age-related decline in spatial learning abilities in mice
MC Buhot et al.
BEHAVIOURAL BRAIN RESEARCH (2003)
Agonist-induced phosphorylation of the serotonin 5-HT2C receptor regulates its interaction with multiple PDZ protein 1
LL Parker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Variations in the 5-hydroxytryptamine type 3B receptor gene as predictors of the efficacy of antiemetic treatment in cancer patients
PB Tremblay et al.
JOURNAL OF CLINICAL ONCOLOGY (2003)
SB-656104-A, a novel selective 5-HT7 receptor antagonist, modulates REM sleep in rats
DR Thomas et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
3,4-methylenedioxymethamphetamine (MDMA, Ecstasy) induces fenfluramine-like proliferative actions on human cardiac valvular interstitial cells in vitro
V Setola et al.
MOLECULAR PHARMACOLOGY (2003)
The neurobiology and control of anxious states
MJ Millan
PROGRESS IN NEUROBIOLOGY (2003)
Brain edema induced by in vitro ischemia:: causal factors and neuroprotection
DG MacGregor et al.
JOURNAL OF NEUROCHEMISTRY (2003)
BIMU 1 and RS 67333, two 5-HT4 receptor agonists, modulate spontaneous alternation deficits induced by scopolamine in the mouse
V Lelong et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2003)
The hypothermic effect of 5-CT in mice is mediated through the 5-HT7 receptor
MR Guscott et al.
NEUROPHARMACOLOGY (2003)
The G-protein-coupled receptors in the human genome form five main families.: Phylogenetic analysis, paralogon groups, and fingerprints
R Fredriksson et al.
MOLECULAR PHARMACOLOGY (2003)
Large-scale identification and characterization of human genes that activate NF-κB and MAPK signaling pathways
A Matsuda et al.
ONCOGENE (2003)
Cloning, physical mapping and expression analysis of the human 5-HT3 serotonin receptor-like genes HTR3C, HTR3D and HTR3E
B Niesler et al.
GENE (2003)
Intra-prefrontal S-OH-DPAT and M100907 improve visuospatial attention and decrease impulsivity on the five-choice serial reaction time task in rats
CA Winstanley et al.
PSYCHOPHARMACOLOGY (2003)
Fluoxetine suppresses morphine tolerance and dependence: Modulation of NO-cGMP/DA/serotoninergic pathways
VP Singh et al.
METHODS AND FINDINGS IN EXPERIMENTAL AND CLINICAL PHARMACOLOGY (2003)
Serotonin is a novel survival factor of cardiomyocytes:: mitochondria as a target of 5-HT2B-receptor signaling
CG Nebigil et al.
FASEB JOURNAL (2003)
Serotonin upregulates the activity of phagocytosis through 5-HT1A receptors
M Freire-Garabal et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Phoneutria nigriventer spider venom activates 5-HT4 receptors in rat-isolated vagus nerve
SKP Costa et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Selective serotonin reuptake inhibitors directly signal for apoptosis in biopsy-like Burkitt lymphoma cells
A Serafeim et al.
BLOOD (2003)
The G protein-coupled 5-HT1A receptor causes suppression of caspase-3 through MAPK and protein kinase Cα
T Adayev et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2003)
5-HT7 receptors mediate the inhibitory effect of 5-HT on peristalsis in the isolated guinea-pig ileum
BR Tuladhar et al.
BRITISH JOURNAL OF PHARMACOLOGY (2003)
Polymorphism of the promoter region of the serotonin 5-HT2C receptor gene and clozapine-induced weight gain
GP Reynolds et al.
AMERICAN JOURNAL OF PSYCHIATRY (2003)
Anxiolytic-like effects of 5-HT2 ligands on three mouse models of anxiety
BAN Dhonnchadha et al.
BEHAVIOURAL BRAIN RESEARCH (2003)
Modulation of serotonergic function in rat brain by VN2222, a serotonin Reuptake inhibitor and 5-HTIA receptor agonist
L Romero et al.
NEUROPSYCHOPHARMACOLOGY (2003)
Expression of 5-HT3 receptors by extrinsic duodenal afferents contribute to intestinal inhibition of gastric emptying
HE Raybould et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2003)
Creation, expression, and characterization of a constitutively active mutant of the human serotonin 5-HT6 receptor
A Purohit et al.
SYNAPSE (2003)
Neurogenic dural protein extravasation induced by meta-chlorophenylpiperazine (mCPP) involves nitric oxide and 5-HT2B receptor activation
KW Johnson et al.
CEPHALALGIA (2003)
Neuroendocrine evidence that (S)-2-(chloro-5-fluoro-indol-l-yl)-1-methylethylamine fumarate (Ro 60-0175) is not a selective 5-hydroxytryptamine2C receptor agonist
KJ Damjanoska et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Unaltered agonist potency upon inducible 5-HT7(a) but not 5-HT4(b) receptor expression indicates agonist-independent association of 5-HT7(a) receptor and Gs
S Bruheim et al.
RECEPTORS & CHANNELS (2003)
Regulation of 5-HT1A receptor function in brain following agonist or antidepressant administration
JG Hensler
LIFE SCIENCES (2003)
Serotonin receptor rnRNA expression in rat dorsal root ganglion neurons
R Nicholson et al.
NEUROSCIENCE LETTERS (2003)
Targeted gene deletion of the 5-HT3A receptor subunit produces an anxiolytic phenotype in mice
SP Kelley et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2003)
No hypothermic response to serotonin in 5-HT7 receptor knockout mice
PB Hedlund et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
Inhibitory effect of hippocampal 5-HT1A receptors on human explicit memory
F Yasuno et al.
AMERICAN JOURNAL OF PSYCHIATRY (2003)
Synergistic action of 5-HT2A antagonists and selective serotonin reuptake inhibitors in neuropsychiatric disorders
GJ Marek et al.
NEUROPSYCHOPHARMACOLOGY (2003)
5-HT2 receptor-mediated phosphoinositide hydrolysis in bovine ciliary epithelium
E Inoue-Matsuhisa et al.
JOURNAL OF OCULAR PHARMACOLOGY AND THERAPEUTICS (2003)
Ras-dependent ERK activation by the human Gs-coupled serotonin receptors 5-HT4(b) and 5-HT7(a)
JH Norum et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
5-HT4 receptor ligands:: Applications and new prospects
M Langlois et al.
JOURNAL OF MEDICINAL CHEMISTRY (2003)
The 5-HT1A serotonin receptor is located on calbindin- and parvalbumin-containing neurons in the rat brain
S Aznar et al.
BRAIN RESEARCH (2003)
Synthesis of serotonin by a second tryptophan hydroxylase isoform
DJ Walther et al.
SCIENCE (2003)
Selective interaction of ARF1 with the carboxy-terminal tail domain of the 5-HT2A receptor
DN Robertson et al.
MOLECULAR PHARMACOLOGY (2003)
The 5-HT2A receptor antagonist M100,907 attenuates motor and 'impulsive-type' behaviours produced by NMDA receptor antagonism
GA Higgins et al.
PSYCHOPHARMACOLOGY (2003)
The PDZ-binding domain is essential for the dendritic targeting of 5-HT2A serotonin receptors in cortical pyramidal neurons in vitro
Z Xia et al.
NEUROSCIENCE (2003)
Dysfunctional attitudes and 5-HT2 receptors during depression and self-harm
JH Meyer et al.
AMERICAN JOURNAL OF PSYCHIATRY (2003)
Serotonin 5-hydroxytryptamine(2A) receptor-coupled phospholipase C and phospholipase A(2) signaling pathways have different receptor reserves
DM Kurrasch-Orbaugh et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
5-hydroxytryptamine(2A) receptors regulate sympathetic nerves constricting the cutaneous vascular bed in rabbits and rats
WW Blessing et al.
NEUROSCIENCE (2003)
Ca2+ responses in Chinese hamster ovary-K1 cells demonstrate an atypical pattern of ligand-induced 5-HT1A receptor activation
PJ Pauwels et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2003)
Recombinant human serotonin 5A receptors stably expressed in C6 ghoma cells couple to multiple signal transduction pathways
M Noda et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Coupling of neuronal 5-HT7 receptors to activation of extracellular-regulated kinase through a protein kinase A-independent pathway that can utilize Epac
SL Lin et al.
JOURNAL OF NEUROCHEMISTRY (2003)
Serotonin receptors: guardians of stable breathing
DW Richter et al.
TRENDS IN MOLECULAR MEDICINE (2003)
The serotonin 5-HT4 receptor and the amyloid precursor protein processing
F Lezoualc'h et al.
EXPERIMENTAL GERONTOLOGY (2003)
Pharmacokinetic-pharmacodynamic modeling of buspirone and its metabolite 1-(2-pyrimidinyl)-piperazine in rats
KP Zuideveld et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Phospholipase D activation by endogenous 5-hydroxytryptamine 2C receptors is mediated by Gα13 and pertussis toxin-insensitive Gβγ subunits
L McGrew et al.
MOLECULAR PHARMACOLOGY (2002)
Preclinical studies characterizing the anti-migraine and cardiovascular effects of the selective 5-HT1D receptor agonist PNU-142633
RB McCall et al.
CEPHALALGIA (2002)
-759C/T genetic variation of 5HT2C receptor and clozapine-induced weight gain
VS Basile et al.
LANCET (2002)
-759C/T genetic variation of 5HT2C receptor and clozapine-induced weight gain
SJ Tsai et al.
LANCET (2002)
Serotonin-induced MMP-13 production is mediated via phospholipase C, protein kinase C, and ERK1/2 in rat uterine smooth muscle cells
JKS Shum et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Activation of extracellular-regulated kinase by 5-hydroxytryptamine2A receptors in PC12 cells is protein kinase C-independent and requires calmodulin and tyrosine kinases
JC Quinn et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Sleep and sleep homeostasis in mice lacking the 5-HT2c receptor
MG Frank et al.
NEUROPSYCHOPHARMACOLOGY (2002)
Large-amplitude 5-HT1A receptor activation:: a new mechanism of profound, central analgesia
FC Colpaert et al.
NEUROPHARMACOLOGY (2002)
5-HT1A receptor activation and anti-cataleptic effects:: high-efficacy agonists maximally inhibit haloperidol-induced catalepsy
EPM Prinssen et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
The need to feed: Homeostatic and hedonic control of eating
CB Saper et al.
NEURON (2002)
5-hydroxytryptamine2B receptor function is enhanced in the Nω-nitro-L-arginine hypertensive rat
A Russell et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Function of the serotonin 5-hydroxytryptamine 2B receptor in pulmonary hypertension
JM Launay et al.
NATURE MEDICINE (2002)
Molecular cloning and tissue distribution of mRNA encoding procine 5-HT7 receptor and its comparison with the structure of other species
P Bhalla et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2002)
Antibody capture assay reveals bell-shaped concentration-response isotherms for h5-HT1A receptor-mediated Gαi3 activation:: Conformational selection by high-efficacy agonists, and relationship to trafficking of receptor signaling
A Newman-Tancredi et al.
MOLECULAR PHARMACOLOGY (2002)
5-HT4 receptors exert a frequency-related facilitatory control on dorsal raphe nucleus 5-HT neuronal activity
G Lucas et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2002)
Cation-π interactions in ligand recognition by serotonergic (5-HT3A) and nicotinic acetylcholine receptors:: The anomalous binding properties of nicotine
DL Beene et al.
BIOCHEMISTRY (2002)
Serotonin-transporter polymorphism pharmacogenetics in diarrhea-predominant irritable bowel syndrome
M Camilleri et al.
GASTROENTEROLOGY (2002)
Endogenous kynurenines as targets for drug discovery and development
TW Stone et al.
NATURE REVIEWS DRUG DISCOVERY (2002)
Impaired gastrocolonic response and peristaltic reflex in slow-transit constipation:: role of 5-HT3 pathways
ES Björnsson et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2002)
SL65.0155, a novel 5-hydroxytryptamine4 receptor partial agonist with potent cognition-enhancing properties
PC Moser et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
Activation of central melanocortin pathways by fenfluramine
LK Heisler et al.
SCIENCE (2002)
A 5-HT4 receptor transmembrane network implicated in the activity of inverse agonists but not agonists
L Joubert et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Nuclei and subnuclei gene expression profiling in mammalian brain
P Bonaventure et al.
BRAIN RESEARCH (2002)
Reconsideration of 5-hydroxytryptamine (5-HT)7 receptor distribution using [3H]5-carboxamidotryptamine and [3H]8-hydroxy-2-(di-n-propylamino)tetraline:: Analysis in brain of 5-HT1A knockout and 5-HT1A/1B double-knockout mice
P Bonaventure et al.
JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS (2002)
5-HT-induced, 5-HT3 receptor-mediated, and ruthenium red- and capsaicin-sensitive positive chronotropic effects in the isolated guinea pig atrium
H Nishio et al.
JAPANESE JOURNAL OF PHARMACOLOGY (2002)
Multiple 5-HT receptors are involved in the effects of acute MDMA treatment: studies on locomotor activity and responding for conditioned reinforcement
PJ Fletcher et al.
PSYCHOPHARMACOLOGY (2002)
Patient-tailored antiemetic treatment with 5-hydroxytryptamine type 3 receptor antagonists according to cytochrome P-450 2D6 genotypes
R Kaiser et al.
JOURNAL OF CLINICAL ONCOLOGY (2002)
5-hydroxytryptamine 4(a) receptor is coupled to the Gα subunit of heterotrimeric G13 protein
EG Ponimaskin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Repeated treatment with antidepressants differentially alters 5-HT1A agonist-stimulated [35S]GTPγS binding in rat brain regions
C Shen et al.
NEUROPHARMACOLOGY (2002)
5-Hydroxytryptamine1B/1D and 5-hydroxytryptamine1F receptors inhibit capsaicin-induced c-fos immunoreactivity within mouse trigeminal nucleus caudalis
DD Mitsikostas et al.
CEPHALALGIA (2002)
Localization of 5-HT2A, 5-HT3, 5-HT5A and 5-HT7 receptor-like immunoreactivity in the rat cerebellum
FJ Geurts et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2002)
Synaptic multiprotein complexes associated with 5-HT2C receptors:: a proteomic approach
C Bécamel et al.
EMBO JOURNAL (2002)
Activation of 5-HT7 receptor in rat glomerulosa cells is associated with an increase in adenylyl cyclase activity and calcium influx through T-type calcium channels
S Lenglet et al.
ENDOCRINOLOGY (2002)
5HT2A receptors:: location and functional analysis in intestines of wild-type and 5-HT2A knockout mice
E Fiorica-Howells et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2002)
Stimulation of 5-HT2 receptors in prefrontal pyramidal neurons inhibits Cav1.2 L-type Ca2+ currents via a PLCβ/IP3/calcineurin signaling cascade
M Day et al.
JOURNAL OF NEUROPHYSIOLOGY (2002)
Altered editing of serotonin 2C receptor pre-mRNA in the prefrontal cortex of depressed suicide victims
I Gurevich et al.
NEURON (2002)
An investigation of the role of 5-HT2C receptors in modifying ethanol self-administration behaviour
DM Tomkins et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2002)
5-hydroxytryptamine drives apoptosis in biopsylike Burkitt lymphoma cells: reversal by selective serotonin reuptake inhibitors
A Serafeim et al.
BLOOD (2002)
Effects of the 5-HT7 receptor antagonist SB-258741 in animal models for schizophrenia
B Pouzet et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2002)
Effects of motilin on human interdigestive gastrointestinal and gallbladder motility, and involvement of 5HT3 receptors
YC Luiking et al.
NEUROGASTROENTEROLOGY AND MOTILITY (2002)
Molecular, pharmacological and functional diversity of 5-HT receptors
D Hoyer et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2002)
Serotonin 2C receptor agonists and the behavioural satiety sequence in mice
KN Hewitt et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2002)
Serotonin 5-HT2C receptors in nucleus accumbens regulate expression of the hyperlocomotive and discriminative stimulus effects of cocaine
M Filip et al.
PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR (2002)
DARPP-32 mediates serotonergic neurotransmission in the forebrain
P Svenningsson et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2002)
Molecular cloning and expression of the porcine trigeminal ganglion cDNA encoding a 5-ht1F receptor
P Bhalla et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2002)
Upregulation of arterial serotonin 1B and 2B receptors in deoxycorticosterone acetate-salt hypertension
AKL Banes et al.
HYPERTENSION (2002)
Modulation by serotonin 5-HT4 receptors of long-term potentiation and depotentiation in the dentate gyrus of freely moving rats
A Kulla et al.
CEREBRAL CORTEX (2002)
Effects of 5-HT3 antagonism on postprandial gastric volume and symptoms in humans
B Kuo et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2002)
5-HT6 receptor antagonism potentiates the behavioral and neurochemical effects of amphetamine but not cocaine
KJ Frantz et al.
NEUROPHARMACOLOGY (2002)
The 5-hydroxytryptamine(4a) receptor is palmitoylated at two different sites, and acylation is critically involved in regulation of receptor constitutive activity
EG Ponimaskin et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2002)
Characterization of sumatriptan-induced contractions in human isolated blood vessels using selective 5-HT1B and 5-HT1D receptor antagonists and in situ hybridization
RWM van den Broek et al.
CEPHALALGIA (2002)
Pharmacological studies of the acute effects of (+)-3,4-methylenedioxymethamphetamine on locomotor activity: Role of 5-HT1B/1D and 5-HT2 receptors
MG Bankson et al.
NEUROPSYCHOPHARMACOLOGY (2002)
Does intravenous ondansetron affect gastric emptying of a solid meal, gastric electrical activity or blood hormone levels in healthy volunteers
P Netzer et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2002)
Cloning and characterization of a novel human 5-HT4 receptor variant that lacks the alternatively spliced carboxy terminal exon. RT-PCR distribution in human brain and periphery of multiple 5-HT4 receptor variants
MT Vilaro et al.
NEUROPHARMACOLOGY (2002)
[H-3]-SB-269970 radiolabels 5-HT7 receptors in rodent, pig and primate brain tissues
DR Thomas et al.
NEUROPHARMACOLOGY (2002)
Differences in signal transduction of two 5-HT4 receptor splice variants: Compound specificity and dual coupling with G alpha s- and G alpha i/o-proteins
A Pindon et al.
MOLECULAR PHARMACOLOGY (2002)
Localization of 5-HT2A receptors on dopamine cells in subnuclei of the midbrain A10 cell group
C Nocjar et al.
NEUROSCIENCE (2002)
Similar ultrastructural distribution of the 5-HT2A serotonin receptor and microtubule-associated protein MAP1A in cortical dendrites of adult rat
V Cornea-Hebert et al.
NEUROSCIENCE (2002)
Characterization of phospholipase C activity at h5-HT2C compared with h5-HT2B receptors: influence of novel ligands upon membrane-bound levels of [H-3]phosphatidylinositols
D Cussac et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2002)
The human 5-HT7 serotonin receptor splice variants: constitutive activity and inverse agonist effects
KA Krobert et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
Evidence for a centrally located gate in the pore of a serotonin-gated ion channel
S Panicker et al.
JOURNAL OF NEUROSCIENCE (2002)
5-HT2B receptors play a key role in mediating the excitatory effects of 5-HT in human colon in vitro
RA Borman et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
The atypical 5-HT2 receptor mediating tachycardia in pithed rats: pharmacological correlation with the 5-HT2A receptor subtype
D Centurion et al.
BRITISH JOURNAL OF PHARMACOLOGY (2002)
Mast cells and inflammatory mediators in chronic ulcerative colitis
II Stoyanova et al.
ACTA HISTOCHEMICA (2002)
Effects of newer Antipsychotics on extrapyramidal function
D Tarsy et al.
CNS DRUGS (2002)
Involvement of T-type calcium channels in the mechanism of action of 5-HT in rat glomerulosa cells: A novel signaling pathway for the 5-HT7 receptor
S Lenglet et al.
ENDOCRINE RESEARCH (2002)
5-HT7 receptor and β2-adrenoceptor share in the inhibition of porcine uterine contractility in a muscle layer-dependent manner
T Kitazawa et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2001)
The serotonin 5-HT2B receptor from the puffer fish Tetraodon fluviatilis:: cDNA cloning, genomic organization and alternatively spliced variants
S De Lucchini et al.
MOLECULAR BRAIN RESEARCH (2001)
The role of Kv1.2-containing potassium channels in serotonin-induced glutamate release from thalamocortical terminals in rat frontal cortex
EK Lambe et al.
JOURNAL OF NEUROSCIENCE (2001)
Contribution of the 5-HT1B receptor to hypoxia-induced pulmonary hypertension -: Converging evidence using 5-HT1B-receptor knockout mice and the 5-HT1B/1D-receptor antagonist GR127935
A Keegan et al.
CIRCULATION RESEARCH (2001)
Underediting of glutamate receptor GluR-B mRNA in malignant gliomas
S Maas et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2001)
The impact of impulsivity on cocaine use and retention in treatment
FG Moeller et al.
JOURNAL OF SUBSTANCE ABUSE TREATMENT (2001)
Enhancement of place and object recognition memory in young adult and old rats by RS 67333, a partial agonist of 5-HT4 receptors
L Lamirault et al.
NEUROPHARMACOLOGY (2001)
Allosteric modulation of the human 5-HT7A receptor by lipidic amphipathic compounds
GL Alberts et al.
MOLECULAR PHARMACOLOGY (2001)
RNA editing of the human serotonin 5-HT2C receptor alters receptor-mediated activation of G13 protein
RD Price et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Serotonin 5-HT1A agonist improves motor complications in rodent and primate parkinsonian models
F Bibbiani et al.
NEUROLOGY (2001)
N-[3-(2-dimethylaminoethyl)-2-methyl-1H-indol-5-yl]-4-fluorobenzamide:: A potent, selective, and orally active 5-HT1F receptor agonist potentially useful for migraine therapy
YC Xu et al.
JOURNAL OF MEDICINAL CHEMISTRY (2001)
Structural and electrostatic properties of the 5-HT3 receptor pore revealed by substituted cysteine accessibility mutagenesis
DC Reeves et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Multiplicity of mechanisms of serotonin receptor signal transduction
JR Raymond et al.
PHARMACOLOGY & THERAPEUTICS (2001)
Psychiatric aspects of impulsivity
FG Moeller et al.
AMERICAN JOURNAL OF PSYCHIATRY (2001)
Selective seratonin 1F (5-HT1F) receptor agonist LY334370 for acute migraine:: a randomised controlled trial
DJ Goldstein et al.
LANCET (2001)
Expression patterns of 5-HT7 receptor isoforms in the rat digestive tract
HH Liu et al.
LIFE SCIENCES (2001)
Effects of alosetron on spontaneous migrating motor complexes in murine small and large bowel in vitro
TG Bush et al.
AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY (2001)
Activation of Erk mitogen-activated protein kinase proteins by vascular serotonin receptors
SW Watts et al.
JOURNAL OF CARDIOVASCULAR PHARMACOLOGY (2001)
Enhancement of cognitive performance in schizophrenia by addition of tandospirone to neuroleptic treatment
T Sumiyoshi et al.
AMERICAN JOURNAL OF PSYCHIATRY (2001)
Regional distribution and cellular localization of 5-HT2C receptor mRNA in monkey brain:: Comparison with [3H]mesulergine binding sites and choline acetyltransferase mRNA
JF López-Giménez et al.
SYNAPSE (2001)
Heterodimerization of G-protein-coupled receptors: pharmacology, signaling and trafficking
LA Devi
TRENDS IN PHARMACOLOGICAL SCIENCES (2001)
Selective deletion of leptin receptor in neurons leads to obesity
P Cohen et al.
JOURNAL OF CLINICAL INVESTIGATION (2001)
RNA-editing of the 5-HT2C receptor alters agonist-receptor-effector coupling specificity
KA Berg et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
RS 67333 and D-cycloserine accelerate learning acquisition in the rat
V Lelong et al.
NEUROPHARMACOLOGY (2001)
Sertindole is a serotonin 5-HT2c inverse agonist and decreases agonist but not antagonist binding to 5-HT2c receptors after chronic treatment
J Hietala et al.
PSYCHOPHARMACOLOGY (2001)
Activation of 5-HT2C receptors reduces the locomotor and rewarding effects of nicotine
AJ Grottick et al.
PSYCHOPHARMACOLOGY (2001)
Safety and efficacy of PNU-142633, a selective 5-HT1D agonist, in patients with acute migraine
B Gomez-Mancilla et al.
CEPHALALGIA (2001)
Agonist-induced functional desensitization of recombinant human 5-HT2 receptors expressed in CHO-K1 cells
RHP Porter et al.
BIOCHEMICAL PHARMACOLOGY (2001)
5-HT1B and 5-HT1D receptors in the human trigeminal ganglion:: co-localization with calcitonin gene-related peptide, substance P and nitric oxide synthase
MY Hou et al.
BRAIN RESEARCH (2001)
Expression of serotonin receptors in bone
I Westbroek et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Sorting nexin-14, a gene expressed in motoneurons trapped by an in vitro preselection method
P Carroll et al.
DEVELOPMENTAL DYNAMICS (2001)
SB-243213;: a selective 5-HT2C receptor inverse agonist with improved anxiolytic profile:: lack of tolerance and withdrawal anxiety
MD Wood et al.
NEUROPHARMACOLOGY (2001)
A role for 5-ht6 receptors in retention of spatial learning in the Morris water maze
ML Woolley et al.
NEUROPHARMACOLOGY (2001)
Association between the 5′ UTR variant C178T of the serotonin receptor gene HTR3A and bipolar affective disorder
B Niesler et al.
PHARMACOGENETICS (2001)
Changes of the expression of 5-HT receptor subtype mRNAs in rat dorsal root ganglion by complete Freund's adjuvant-induced inflammation
SX Wu et al.
NEUROSCIENCE LETTERS (2001)
The N-methyl-D-aspartate receptor channel blockers memantine, MRZ 2/579 and other amino-alkyl-cyclohexanes antagonise 5-HT3 receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive manner
G Rammes et al.
NEUROSCIENCE LETTERS (2001)
Cloning of the mouse 5-HT6 serotonin receptor and mutagenesis studies of the third cytoplasmic loop
R Kohen et al.
MOLECULAR BRAIN RESEARCH (2001)
Ablation of serotonin 5-HT2B receptors in mice leads to abnormal cardiac structure and function
CG Nebigil et al.
CIRCULATION (2001)
Co-localization of 5-HT1B/1B/1F receptors and glutamate in trigeminal ganglia in rats
QP Ma
NEUROREPORT (2001)
Affinity of serotonin receptor antagonists and agonists to recombinant and native α1-adrenoceptor subtypes
R Yoshio et al.
JAPANESE JOURNAL OF PHARMACOLOGY (2001)
Colocalization of CGRP with 5-HT1B/1D receptors and substance P in trigeminal ganglion neurons in rats
QP Ma et al.
EUROPEAN JOURNAL OF NEUROSCIENCE (2001)
The cloned human 5-HT7 receptor splice variants:: a comparative characterization of their pharmacology, function and distribution
KA Krobert et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2001)
The effect of tandospirone, a serotonin1A agonist, on memory function in schizophrenia
T Sumiyoshi et al.
BIOLOGICAL PSYCHIATRY (2001)
Genetic variation in the 5-HT5A receptor gene in patients with bipolar disorder and major depression
B Arias et al.
NEUROSCIENCE LETTERS (2001)
RNA editing of the human serotonin 5-MT2C receptor:: Alterations in suicide and implications for serotonergic pharmacotherapy
CM Niswender et al.
NEUROPSYCHOPHARMACOLOGY (2001)
Human 5-HT5 receptors:: the 5-HT5A receptor is functional but the 5-HT5B receptor was lost during mammalian evolution
R Grailhe et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2001)
Interaction of serotonin 5-hydroxytryptamine type 2C receptors with PDZ10 of the multi-PDZ domain protein MUPP1
C Bécamel et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
5-HT7 receptor mRNA expression in human trigeminal ganglia
JA Terrón et al.
NEUROSCIENCE LETTERS (2001)
Subcellular distribution of 5-HT1B and 5-HT7 receptors in the mouse suprachiasmatic nucleus
MA Belenky et al.
JOURNAL OF COMPARATIVE NEUROLOGY (2001)
Conversion of the ion selectivity of the 5-HT3A receptor from cationic to anionic reveals a conserved feature of the ligand-gated ion channel superfamily.
MJ Gunthorpe et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
A dose-ranging, placebo-controlled, randomized trial of alosetron in patients with functional dyspepsia
NJ Talley et al.
ALIMENTARY PHARMACOLOGY & THERAPEUTICS (2001)
The dynamin-dependent, arrestin-independent internalization of 5-hydroxytryptamine 2A (5-HT2A) serotonin receptors reveals differential sorting of arrestins and 5-HT2A receptors during endocytosis
A Bhatnagar et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
Differential occupancy of somatodendritic and postsynaptic 5HT1A receptors by pindolol:: A dose-occupancy study with [11C]WAY 100635 and positron emission tomography in humans
D Martinez et al.
NEUROPSYCHOPHARMACOLOGY (2001)
Association of a 5-MT5A receptor polymorphism, Pro15Ser, to schizophrenia
N Iwata et al.
MOLECULAR PSYCHIATRY (2001)
The GR127935-sensitive 5-HT1 receptors mediating canine internal carotid vasoconstriction:: resemblance to the 5-HT1B, but not to the 5-HT1D or 5-ht1F, receptor subtype
D Centurión et al.
BRITISH JOURNAL OF PHARMACOLOGY (2001)
Pharmacological characterisation of human 5-HT2 receptor subtypes
JC Jerman et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2001)
Transcriptional mechanisms for induction of 5-HT1A receptor mRNA and protein in activated B and T lymphocytes
M Abdouh et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2001)
5-HT4(a) and 5-HT4(b) receptors have nearly identical pharmacology and are both expressed in human atrium and ventricle
T Bach et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2001)
The impact of sucrose-derived unconditioned and conditioned negative feedback on the microstructure of ingestive behavior
JD Davis et al.
PHYSIOLOGY & BEHAVIOR (2001)
Lack of association between the T→C 267 serotonin 5-MT6 receptor gene (HTR6) polymorphism and prediction of response to clozapine in schizophrenia
M Masellis et al.
SCHIZOPHRENIA RESEARCH (2001)
5-HT7 receptors activate the mitogen activated protein kinase extracellular signal related kinase in cultured rat hippocampal neurons
H Errico et al.
NEUROSCIENCE (2001)
m-Chlorophenylpiperazine excites non-dopaminergic neurons in the rat substantia nigra and ventral tegmental area by activating serotonin-2C receptors
G Di Giovanni et al.
NEUROSCIENCE (2001)
Unravelling the pharmacological profile of the canine external carotid vasodilator '5-HT1-like receptors: coexistence of sympatho-inhibitory 5-HT1B and postjunctional 5-HT7 receptors
CM Villalon et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2001)
Localization of 5-HT7 receptors in rat brain by immunocytochemistry, in situ hybridization, and agonist stimulated cFos expression
JF Neumaier et al.
JOURNAL OF CHEMICAL NEUROANATOMY (2001)
Conserved helix 7 tyrosine functions as an activation relay in the serotonin 5HT2C receptor
A Rosendorff et al.
MOLECULAR BRAIN RESEARCH (2000)
In vivo modulation of vagal-identified dorsal medullary neurones by activation of different 5-hydroxytryptamine2 receptors in rats
C Sévoz-Couche et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Regulation of central synaptic transmission by 5-HT1B auto- and heteroreceptors
H Morikawa et al.
MOLECULAR PHARMACOLOGY (2000)
Collar-induced elevation of mRNA and functional activity of 5-HT1B receptor in the rabbit carotid artery
IS Geerts et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Modified 5-HT3A receptor function by co-expression of alternatively spliced human 5-HT3A receptor isoforms
M Brüss et al.
NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY (2000)
Effects of a serotonin 5-HT4 receptor antagonist SE-207266 on gastrointestinal motor and sensory function in humans
AE Bharucha et al.
GUT (2000)
Pharmacological characterization of the human 5-HT4(d) receptor splice variant stably expressed in Chinese hamster ovary cells
J Mialet et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Oligomerization of dopamine and serotonin receptors
SP Lee et al.
NEUROPSYCHOPHARMACOLOGY (2000)
Similarities in the action of Ro 60-0175, a 5-HT2C receptor agonist, and d-fenfluramine on feeding patterns in the rat
PG Clifton et al.
PSYCHOPHARMACOLOGY (2000)
Contractile responses to sumatriptan and ergotamine in the rabbit saphenous vein:: effect of selective 5-HT1F receptor agonists and PGF2α
ML Cohen et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Serotonin 2B receptor is required for heart development
CG Nebigil et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Deletion of the serotonin 5-HT2C receptor PDZ recognition motif prevents receptor phosphorylation and delays resensitization of receptor responses
JR Backstrom et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
The 5HT1B receptor agonist, CP-93129, inhibits [3H]-GABA release from rat globus pallidus slices and reverses akinesia following intrapallidal injection in the reserpine-treated rat
A Chadha et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
A comparison of the behavioural effects of 5-HT2A and 5-HT2C receptor agonists in the pigeon
MC Wolff et al.
BEHAVIOURAL PHARMACOLOGY (2000)
Localization of 5-HT6 receptors at the plasma membrane of neuronal cilia in the rat brain
I Brailov et al.
BRAIN RESEARCH (2000)
The putative silent 5-HT1A receptor antagonist, WAY 100635, has inverse agonist properties at cloned human 5-HT1A receptors
C Cosi et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2000)
Cloning, expression, and characterization of ferret 5-HT3 receptor subunit
S Mochizuki et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2000)
Leftward shift in the acquisition of cocaine self-administration in isolation-reared rats: relationship to extracellular levels of dopamine, serotonin and glutamate in the nucleus accumbens and amygdala-striatal FOS expression
SR Howes et al.
PSYCHOPHARMACOLOGY (2000)
Somatodendritic 5-HT1A autoreceptors mediate the anti-aggressive actions of 5-HT1A receptor agonists in rats:: An ethopharmacological study with S-15535, alnespirone, and WAY-100635
SF de Boer et al.
NEUROPSYCHOPHARMACOLOGY (2000)
Pharmacological properties of 5-hydroxytryptamine4 receptor antagonists on constitutively active wild-type and mutated receptors
S Claeysen et al.
MOLECULAR PHARMACOLOGY (2000)
Localization of serotonin5A receptors in discrete regions of the circadian timing system in the Syrian hamster
MJ Duncan et al.
BRAIN RESEARCH (2000)
Association analysis of the 5-HT5A gene in depression, psychosis and antipsychotic response
JT Birkett et al.
NEUROREPORT (2000)
Localization of 5-ht5A receptor-like immunoreactivity in the rat brain
KR Oliver et al.
BRAIN RESEARCH (2000)
Increased defecation during stress or after 5-hydroxytryptophan:: selective inhibition by the 5-HT4 receptor antagonist, SB-207266
GJ Sanger et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Repeated treatment with 8-OH-DPAT induces tolerance to its ability to produce the 5-HT1A behavioural syndrome, but not to its ability to attenuate haloperidol-induced
EPM Prinssen et al.
BEHAVIOURAL PHARMACOLOGY (2000)
The involvement of intracellular Ca2+ in 5-HT1B/1D receptor-mediated contraction of the rabbit isolated renal artery
PB Hill et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Characterization of SB-269970-A, a selective 5-HT7 receptor antagonist
JJ Hagan et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Further evidence that 5-HT-induced relaxation of pig pulmonary artery is mediated by endothelial 5-HT2B receptors
E Glusa et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Biochemical and electrophysiological evidence that RO 60-0175 inhibits mesolimbic dopaminergic function through serotonin2C receptors
M Di Matteo et al.
BRAIN RESEARCH (2000)
Ultrastructural localization of the serotonin 2A receptor in dopaminergic neurons in the ventral tegmental area
MD Doherty et al.
BRAIN RESEARCH (2000)
Identification of the adenylyl cyclase-activating 5-hydroxytryptamine receptor subtypes expressed in the rat submandibular gland
DM Bourdon et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
Cellular localization of serotonin2A (5HT2A) receptors in the rat brain
TJ Xu et al.
BRAIN RESEARCH BULLETIN (2000)
5-Hydroxytryptamine2B receptors stimulate Ca2+ increases in cultured astrocytes from three different brain regions
N Sandén et al.
NEUROCHEMISTRY INTERNATIONAL (2000)
Activation of intrinsic afferent pathways in submucosal ganglia of the guinea pig small intestine
H Pan et al.
JOURNAL OF NEUROSCIENCE (2000)
An improved in vitro bioassay for the study of 5-HT4 receptors in the human isolated large intestinal circular muscle
NH Prins et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
5-Hydroxytryptamine 2B receptor regulates cell-cycle progression: Cross-talk with tyrosine kinase pathways
CG Nebigil et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Dissecting G protein-coupled receptor signaling pathways with membrane-permeable blocking peptides -: Endogenous 5-HT2C receptors in choroid plexus epithelial cells
M Chang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
2-Substituted tryptamines:: Agents with selectivity for 5-HT6 serotonin receptors
RA Glennon et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
Separate systems for serotonin and leptin in appetite control
JCG Halford et al.
ANNALS OF MEDICINE (2000)
5-HT2A receptors stimulate mitogen-activated protein kinase via H2O2 generation in rat renal mesangial cells
EL Greene et al.
AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY (2000)
Characterization of receptor-mediated [35S]GTPγS binding to cortical membranes from postmortem human brain
J González-Maeso et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2000)
A novel, potent, and selective 5-HT7 antagonist:: (R)-3-(2-(2-(4-methylpiperidin-1-yl)-ethyl)pyrrolidine-1-sulfonyl)phenol (SB-269970)
PJ Lovell et al.
JOURNAL OF MEDICINAL CHEMISTRY (2000)
PDZ-dependent activation of nitric-oxide syntheses by the serotonin 2B receptor
P Manivet et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2000)
No contractile effect for 5-HT1D and 5-HT1F receptor agonists in human and bovine cerebral arteries:: similarity with human coronary artery
I Bouchelet et al.
BRITISH JOURNAL OF PHARMACOLOGY (2000)
TASK-1, a two-pore domain K+ channel, is modulated by multiple neurotransmitters in motoneurons
EM Talley et al.
NEURON (2000)
Structure of the human serotonin 5-HT4 receptor gene and cloning of a novel 5-HT4 splice variant
E Bender et al.
JOURNAL OF NEUROCHEMISTRY (2000)
The 4′lysine in the putative channel lining domain affects desensitization but not the single-channel conductance of recombinant homomeric 5-HT3A receptors
MJ Gunthorpe et al.
JOURNAL OF PHYSIOLOGY-LONDON (2000)
Effects of RO 60 0175, a 5-HT2C receptor agonist, in three animal models of anxiety
G Kennett et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2000)
5-HT5a receptors in the carotid body chemoreception pathway of rat
ZY Wang et al.
NEUROSCIENCE LETTERS (2000)
Mechanisms of agonism and inverse agonism at serotonin 5-HT1A receptors
DJ McLoughlin et al.
JOURNAL OF NEUROCHEMISTRY (2000)
The terminals of myenteric intrinsic primary afferent neurons of the guinea-pig ileum are excited by 5-hydroxytryptamine acting at 5-hydroxytryptamine-3 receptors
PP Bertrand et al.
NEUROSCIENCE (2000)
Olanzapine increases slow-wave sleep: Evidence for blockade of central 5-HT2C receptors in vivo
AL Sharpley et al.
BIOLOGICAL PSYCHIATRY (2000)
Presence of a 5-HT7 receptor positively coupled to adenylate cyclase activation in human granulosa-lutein cells
C Graveleau et al.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM (2000)
Serotonin and the 5-HT2B receptor in the development of enteric neurons
E Fiorica-Howells et al.
JOURNAL OF NEUROSCIENCE (2000)
Differential modulation of the 5-HT4 receptor agonists and antagonist on rat learning and memory
E Marchetti et al.
NEUROPHARMACOLOGY (2000)
Identification of polymorphic loci in the promoter region of the serotonin 5-HT2C receptor gene and their association with obesity and Type II diabetes
X Yuan et al.
DIABETOLOGIA (2000)
Effect of serotonin(4) (5-HT4) receptor agonists on aldosterone secretion in idiopathic hyperaldosteronism
H Lefebvre et al.
ENDOCRINE RESEARCH (2000)
Rat glomerulosa cells express functional 5-HT7 receptors
S Lenglet et al.
ENDOCRINE RESEARCH (2000)
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