4.7 Review

Prospective therapeutic potential of Tanshinone IIA: An updated overview

Journal

PHARMACOLOGICAL RESEARCH
Volume 164, Issue -, Pages -

Publisher

ACADEMIC PRESS LTD- ELSEVIER SCIENCE LTD
DOI: 10.1016/j.phrs.2020.105364

Keywords

Tanshinone; Anti-oxidant; Anti-inflammatory; Cardiovascular disease; Cancer; Nanotherapeutics

Ask authors/readers for more resources

The review collates the pharmacological properties of Tanshinone IIA (Tan IIA) with a special emphasis on its therapeutic potential against diverse diseases, while also discussing possible applications of various therapeutic formulations based on nanotechnology. The convergence of nanomedicine and the therapeutic potential of Tan IIA shows great promise in clinical application.
In the past decades, the branch of complementary and alternative medicine based therapeutics has gained considerable attention worldwide. Pharmacological efficacy of various traditional medicinal plants, their products and/or product derivatives have been explored on an increasing scale. Tanshinone IIA (Tan IIA) is a pharmacologically active lipophilic component of Salvia miltiorrhiza extract. Tan IIA shares a history of high repute in Traditional Chinese Medicine. Reckoning with these, the present review collates the pharmacological properties of Tan IIA with a special emphasis on its therapeutic potential against diverse diseases including cardiovascular diseases, cerebrovascular diseases, cancer, diabetes, obesity and neurogenerative diseases. Further, possible applications of various therapeutic preparations of Tan IIA were discussed with special emphasis on nano-based drug delivery formulations. Considering the tremendous advancement in the field of nanomedicine and the therapeutic potential of Tan IIA, the convergence of these two aspects can be foreseen with great promise in clinical application.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.7
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available