4.7 Article

Multi -task contrastive learning for automatic CT and X-ray diagnosis of COVID-19

Journal

PATTERN RECOGNITION
Volume 114, Issue -, Pages -

Publisher

ELSEVIER SCI LTD
DOI: 10.1016/j.patcog.2021.107848

Keywords

Computed tomography; X-ray; COVID-19; Deep learning; Multi-task learning; Contrastive learning

Funding

  1. Zhejiang Provincial Natural Science Foundation of China [LQ20F030013]
  2. Research Foundation of HwaMei Hospital, University of Chinese Academy of Sciences, China [2020HMZD22]
  3. Ningbo Public Service Technology Foundation, China [202002N3181]
  4. Medical Scientific Research Foundation of Zhejiang Province, China [2021431314]

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The contrastive multi-task convolutional neural network (CMT-CNN) improves the generalization of automatic COVID-19 diagnosis using contrastive learning, achieving diagnosis of COVID-19 and local aggregation through the main and auxiliary tasks. Experimental results demonstrate significant accuracy improvement on CT and X-ray datasets, showcasing the effectiveness of CMT-CNN.
Computed tomography (CT) and X-ray are effective methods for diagnosing COVID-19. Although several studies have demonstrated the potential of deep learning in the automatic diagnosis of COVID-19 using CT and X-ray, the generalization on unseen samples needs to be improved. To tackle this problem, we present the contrastive multi-task convolutional neural network (CMT-CNN), which is composed of two tasks. The main task is to diagnose COVID-19 from other pneumonia and normal control. The auxiliary task is to encourage local aggregation though a contrastive loss: first, each image is transformed by a series of augmentations (Poisson noise, rotation, etc.). Then, the model is optimized to embed represen-tations of a same image similar while different images dissimilar in a latent space. In this way, CMT-CNN is capable of making transformation-invariant predictions and the spread-out properties of data are pre-served. We demonstrate that the apparently simple auxiliary task provides powerful supervisions to en-hance generalization. We conduct experiments on a CT dataset (4,758 samples) and an X-ray dataset (5,821 samples) assembled by open datasets and data collected in our hospital. Experimental results demonstrate that contrastive learning (as plugin module) brings solid accuracy improvement for deep learning models on both CT (5.49%-6.45%) and X-ray (0.96%-2.42%) without requiring additional annota-tions. Our codes are accessible online. (c) 2021 Elsevier Ltd. All rights reserved.

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