4.5 Article

Switchable Imine and Amine Synthesis Catalyzed by a Well-Defined Cobalt Complex

Journal

ORGANOMETALLICS
Volume 40, Issue 3, Pages 418-426

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.organomet.0c00727

Keywords

-

Funding

  1. National Science Foundation [CHE-1465051, MRI CHE-1626549]
  2. Middle Tennessee State University

Ask authors/readers for more resources

The presence of base plays a crucial role in determining the selectivity of the imine and amine synthesis process. A catalytic amount of base leads to imine formation, while an excess loading of base results in amine product. The product selectivity also strongly depends on the organometallic catalysts used.
Switchable imine and amine synthesis catalyzed by a tripodal ligand-supported well-defined cobalt complex is presented herein. A large variety of primary alcohols and amines were selectively converted to imines or amines in good to excellent yields. It is discovered that the base plays a crucial role on the selectivity. A catalytic amount of base leads to the imine formation, while an excess loading of base results in the amine product. This strategy on product selectivity also strongly depends on the organometallic catalysts in use. We expect that the present study could provide useful insights toward selective organic synthesis and catalyst design.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.5
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available