FlyBase: updates to the Drosophila melanogaster knowledge base

FlyBase (flybase.org) is an essential online database for researchers using Drosophila melanogaster as a model organism, facilitating access to a diverse array of information that includes genetic, molecular, genomic and reagent resources. Here, we describe the introduction of several new features at FlyBase, including Pathway Reports, paralog information, disease models based on orthology, customizable tables within reports and overview displays ('ribbons') of expression and disease data. We also describe a variety of recent important updates, including incorporation of a developmental proteome, upgrades to the GAL4 search tab, additional Experimental Tool Reports, migration to JBrowse for genome browsing and improvements to batch queries/downloads and the Fast-Track Your Paper tool.

Automated summary

FlyBase is an essential online database for researchers using Drosophila melanogaster, offering a wide range of genetic, molecular, genomic resources. New features include Pathway Reports, paralog information, disease models based on orthology, customizable tables, and expression and disease data overview displays. Recent updates include developmental proteome incorporation, GAL4 search tab upgrades, additional Experimental Tool Reports, migration to JBrowse for genome browsing, and improvements to batch queries/downloads and the Fast-Track Your Paper tool.