Journal
NEW ENGLAND JOURNAL OF MEDICINE
Volume 383, Issue 22, Pages 2182-2184Publisher
MASSACHUSETTS MEDICAL SOC
DOI: 10.1056/NEJMc2031173
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Funding
- British Heart Foundation [PG/15/7/31235]
- Wellcome Trust [212183/Z/18/Z]
- Medical Research Council [MR/S021108/1]
- National Institute for Health Research Imperial Biomedical Research Centre
- Imperial Clinical Trials Unit
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Patients who had discontinued statins because of side effects received four bottles of a statin, four bottles of placebo, and four empty bottles, each to be used for 1 month in a random sequence for 12 months. The symptom burden with placebo was 90% of the symptom burden with the statin.
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