4.6 Review

Neurodevelopmental Disorders Commonly Presenting with Sleep Disturbances

Journal

NEUROTHERAPEUTICS
Volume 18, Issue 1, Pages 156-169

Publisher

SPRINGER
DOI: 10.1007/s13311-020-00982-8

Keywords

Neurodevelopmental disorders; Autism; Prader Willi syndrome; Rett syndrome; Williams syndrome; Sleep disorders

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Neurodevelopmental disorders are often accompanied by sleep disturbances, which can manifest as either insomnia or hypersomnia. Clinicians must consider the specific characteristics and diagnostic findings to accurately diagnose and treat sleep disturbances in individuals with NDD. Understanding the different presentations of sleep disturbances is crucial in providing effective care for these patients.
There are multiple disorders of neurodevelopment that present with co-occurring sleep disturbances. Many of these neurodevelopmental disorders (NDD) include sleep disturbances in their diagnostic criteria. Neurobiological, genetic, and environmental factors overlap to cause different sleep disorders in individuals with NDD. Caregivers often present reporting either insomnia or hypersomnia, and based on the clinical history and findings from diagnostic tests, an appropriate diagnosis can be made. It is crucial that clinicians understand the different presentations of sleep disturbances in individuals with NDD.

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