Extent of Resection of Glioblastoma A Critical Evaluation in the Molecular Era

In conclusion, with the 2016 revision of the WHO diagnostic criteria, surgery for adult diffuse gliomas has become even more tightly integrated with radiology and pathology, in both the diagnostic phase as well as the surgical treatment of these diseases. Certain classes of glioma, such as astrocytoma IDH mutant, display a substantial survival benefit in association with maximal resection, regardless of tumor grade under the legacy criteria. Thus, individualization of surgical strategy for patients with gliomas has advanced significantly in the modern era.

Automated summary

With the 2016 revision of the WHO diagnostic criteria, surgery for adult diffuse gliomas has become more integrated with radiology and pathology, leading to significant advancements in individualized surgical strategies for patients with gliomas. Certain classes of glioma, such as astrocytoma IDH mutant, show substantial survival benefits with maximal resection, regardless of tumor grade under the legacy criteria.