Journal
NEURON
Volume 109, Issue 5, Pages -Publisher
CELL PRESS
DOI: 10.1016/j.neuron.2020.12.013
Keywords
-
Categories
Funding
- Wellcome Trust [093104]
- MRC [MR/P013031/1]
- NIH [R01 EB026949, EY014924]
- Pershing Square Foundation
- BBSRC [BB/F021399/1] Funding Source: UKRI
- MRC [MR/P013031/1, MR/K013785/1] Funding Source: UKRI
Ask authors/readers for more resources
Fluctuations in cortical excitability affect sensory processing and behavior. These fluctuations are coordinated across different brain areas, with top-down attention enhancing this coordination. The degree of local state coordination between different areas can predict behavioral performance.
Spontaneous fluctuations in cortical excitability influence sensory processing and behavior. These fluctuations, long thought to reflect global changes in cortical state, were recently found to be modulated locally within a retinotopic map during spatially selective attention. We report that periods of vigorous (On) and faint (Off) spiking activity, the signature of cortical state fluctuations, are coordinated across brain areas with retinotopic precision. Top-down attention enhanced interareal local state coordination, traversing along the reverse cortical hierarchy. The extent of local state coordination between areas was predictive of behavioral performance. Our results show that cortical state dynamics are shared across brain regions, modulated by cognitive demands and relevant for behavior.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available