Journal
DOKLADY BIOCHEMISTRY AND BIOPHYSICS
Volume 470, Issue 1, Pages 368-370Publisher
MAIK NAUKA/INTERPERIODICA/SPRINGER
DOI: 10.1134/S1607672916050197
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- Ministry of Education and Science of the Russian Federation
- Ministry of Education and Science of the Russian Federation [14.607.21.0119, RFMEFI60715X0119]
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3D cultivation of MG-63 osteoblast-like cells on mineralized fibroin scaffolds leads to an increase in the expression of alkaline phosphatase, an early marker of bone formation. Increased expression is associated with the actin cytoskeleton reorganization under the influence of 3D cultivation and osteogenic calcium phosphate component of the microcarrier.
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