Journal
DNA REPAIR
Volume 38, Issue -, Pages 75-83Publisher
ELSEVIER
DOI: 10.1016/j.dnarep.2015.11.010
Keywords
Mismatch repair; Homologous recombination; Homeologous recombination; Antirecombination; Heteroduplex rejection
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Funding
- Netherlands Organization for Scientific Research (NWO) with VIDI Grant [700.58.428]
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DNA mismatch repair influences the outcome of recombination events between diverging DNA sequences. Here we discuss how mismatch repair proteins are active in different homologous recombination subpathways and specific reaction steps, resulting in differential modulation of these recombination events, with a focus on the mechanism of heteroduplex rejection during the inhibition of recombination between slightly diverged (homeologous) DNA sequences. (C) 2015 Elsevier B.V. All rights reserved.
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