A screen of brain organoids to study neurodevelopmental disease

A high-throughput technique has been developed to screen genes implicated in neurodevelopmental diseases in 3D cell cultures. It reveals a mechanism that might be involved in a rare disorder called microcephaly. A CRISPR-based organoid screen for genes involved in microcephaly.

Automated summary

This high-throughput technique screens genes implicated in neurodevelopmental diseases in 3D cell cultures, revealing a potential mechanism involved in a rare disorder known as microcephaly. The CRISPR-based organoid screen targets genes linked to microcephaly.