4.4 Article

Insecticidal activity of copper (II) complexes with flavanone derivatives

Journal

NATURAL PRODUCT RESEARCH
Volume 36, Issue 5, Pages 1342-1345

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2020.1868465

Keywords

Flavonoid derivatives complexes; fall armyworm; Spodoptera frugiperda

Funding

  1. National Council for Scientific and Technological Development [403210/2016-0]
  2. Coordination for the Improvement of Higher Education Personnel (CAPES)
  3. National Institute of Science and Technology for Biorational Control of Insect Pests
  4. Sao Paulo Research Foundation (FAPESP) [2012/25299-6]

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This study demonstrates the insecticidal activity of copper (II) complexes of flavanone derivatives (naringin, naringenin and hesperidin) against Spodoptera frugiperda. Among the tested compounds, complex 9 showed the highest toxicity with a larval mortality rate of 96.66%.
In this work, we describe the insecticidal activity against Spodoptera frugiperda of flavanone derivatives (naringin, naringenin and hesperidin) complexed to copper (II). For the assays, the compounds were incorporated into an artificial diet and offered to S. frugiperda during its larval period. The duration of larval and pupal phases, the weight of pupae and the percentage of dead insects at the end of the larval phase were evaluated. Among the tested compounds, the free flavanones 1 and 3 and the complexes 4 and 6 showed a shortening of the larval phase when compared to the control. Complex 9 showed the highest toxicity, with 96.66% larval mortality. This is the first report on the insecticidal activity of the Cu2+ complexes of the flavanones naringin, naringenin and hesperidin.

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