4.4 Article

A new antidiabetic and anti-inflammatory biflavonoid from Schinus polygama (Cav.) Cabrera leaves

Journal

NATURAL PRODUCT RESEARCH
Volume 36, Issue 5, Pages 1182-1190

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2020.1864365

Keywords

biflavonoid; Schinus polygama; amylase; anti-inflammatory; membrane stabilization

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A new biflavonoid, luteolin-(6 -> 8'')-apigenin, was isolated from the leaves of Schinus polygama. This compound exhibited in vitro antidiabetic effect and anti-inflammatory activity.
A new biflavonoid, luteolin-(6 -> 8'')-apigenin was isolated from 80% methanol extract of Schinus polygama (Cav.) Cabrera leaves (Anacardiaceae). The structure was elucidated by 1D and 2D-NMR spectroscopic data. This compound exhibited in vitro antidiabetic effect via alpha-amylase assay. Furthermore, it possesses anti-inflammatory activity through membrane stabilization effect on erythrocytes.

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