4.4 Article

Two novel compounds from green walnut husks (Juglans mandshurica Maxim.)

Journal

NATURAL PRODUCT RESEARCH
Volume 36, Issue 13, Pages 3389-3395

Publisher

TAYLOR & FRANCIS LTD
DOI: 10.1080/14786419.2020.1860976

Keywords

Green walnut husks of Juglans mandshurica Maxim; macrolide; diarylheptanoids; structural identification

Funding

  1. National Science and Technology Major Project of the Ministry of Science and Technology of China [2018ZX09735005]
  2. Outstanding Young Talents Funding of the Pharmacy College Harbin Medical University [2019-JQ-04]
  3. Hei Long Jiang Postdoctoral Foundation [LBH-Z18105]

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A phytochemical investigation on the ethanol extract of green walnut husks (Juglans mandshurica Maxim.) led to the discovery of two previously unknown compounds, along with 19 known compounds. The structures of these 21 compounds were elucidated by extensive analyses of NMR and HR-MS data, and the basis of spectroscopic analysis.
Phytochemical investigation on the ethanol extract of green walnut husks (Juglans mandshurica Maxim.) led to the isolation of two previously unknown compounds, including a macrolide compound (13S)-8-oxo-(9E, 11E)-8-oxo-octadeca-9,11-dien-13-olide (1) and a diarylheptanoid compound 1-(3 '-methoxy-4 '-hydroxyphenyl)-7-(3 '',4 ''-dimethoxyphenyl)heptan-3-one (2), together with 19 known compounds. The structures of these 21 compounds were elucidated by extensive analyses of NMR and HR-MS data, and the basis of spectroscopic analysis.

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