Related references
Note: Only part of the references are listed.Oncometabolites suppress DNA repair by disrupting local chromatin signalling
Parker L. Sulkowski et al.
NATURE (2020)
Radiation-induced H3K9 tri-methylation in E-cadherin promoter during lung EMT:in vitroandin vivoapproaches using vanillin
SunilGowda Sunnaghatta Nagaraja et al.
FREE RADICAL RESEARCH (2020)
The role of histone methylation in the development of digestive cancers: a potential direction for cancer management
Yuan Chen et al.
SIGNAL TRANSDUCTION AND TARGETED THERAPY (2020)
Sequence-dependent cross-resistance of combined radiotherapy plus BRAFV600E inhibition in melanoma
B. Shannan et al.
EUROPEAN JOURNAL OF CANCER (2019)
Small Molecule Inhibitors of KDM5 Histone Demethylases Increase the Radiosensitivity of Breast Cancer Cells Overexpressing JARID1B
Simone Pippa et al.
MOLECULES (2019)
JMJD2 promotes acquired cisplatin resistance in non-small cell lung carcinoma cells
Lei Duan et al.
ONCOGENE (2019)
Increased EZH2 expression in prostate cancer is associated with metastatic recurrence following external beam radiotherapy
Xiaoning Wu et al.
PROSTATE (2019)
Protein methylation functions as the posttranslational modification switch to regulate autophagy
Rui Li et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2019)
Misrepair in Context: TGFβ Regulation of DNA Repair
Qi Liu et al.
FRONTIERS IN ONCOLOGY (2019)
Radiation-Induced Normal Tissue Damage: Oxidative Stress and Epigenetic Mechanisms
Jinlong Wei et al.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY (2019)
Silencing Lysine-Specific Histone Demethylase 1 (LSD1) Causes Increased HP1-Positive Chromatin, Stimulation of DNA Repair Processes, and Dysregulation of Proliferation by Chk1 Phosphorylation in Human Endothelial Cells
Martyna Wojtala et al.
CELLS (2019)
Down-regulation of JMJD5 suppresses metastasis and induces apoptosis in oral squamous cell carcinoma by regulating p53/NF-κB pathway
Yuan Yao et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
A common Chk1-dependent phenotype of DNA double-strand break suppression in two distinct radioresistant cancer types
Patrick H. Dinkelborg et al.
BREAST CANCER RESEARCH AND TREATMENT (2019)
KDM5B is a master regulator of the H3K4-methylome in stem cells, development and cancer
Besa Xhabija et al.
SEMINARS IN CANCER BIOLOGY (2019)
A change of view: homologous recombination at single-molecule resolution
Kyle Kaniecki et al.
NATURE REVIEWS GENETICS (2018)
SETD1A protects HSCs from activation-induced functional decline in vivo
Kathrin Arndt et al.
BLOOD (2018)
H4K20me2 distinguishes pre-replicative from post-replicative chromatin to appropriately direct DNA repair pathway choice by 53BP1-RIF1-MAD2L2
Marco Simonetta et al.
CELL CYCLE (2018)
Tumor suppressor functions of DAXX through histone H3.3/H3K9me3 pathway in pancreatic NETs
Hiroki Ueda et al.
ENDOCRINE-RELATED CANCER (2018)
Homologous recombination and the repair of DNA double-strand breaks
William Douglass Wright et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2018)
KDM4B promotes DNA damage response via STAT3 signaling and is a target of CREB in colorectal cancer cells
Wei-Wu Deng et al.
MOLECULAR AND CELLULAR BIOCHEMISTRY (2018)
Inhibition of the Histone H3K27 Demethylase UTX Enhances Tumor Cell Radiosensitivity
Barbara H. Rath et al.
MOLECULAR CANCER THERAPEUTICS (2018)
Upregulation of the long noncoding RNA FOXD2-AS1 promotes carcinogenesis by epigenetically silencing EphB3 through EZH2 and LSD1, and predicts poor prognosis in gastric cancer
Tong-peng Xu et al.
ONCOGENE (2018)
KDM5B overexpression predicts a poor prognosis in patients with squamous cell carcinoma of the head and neck
Donghai Huang et al.
JOURNAL OF CANCER (2018)
Histone methylation in DNA repair and clinical practice: new findings during the past 5-years
Shuhua Wei et al.
JOURNAL OF CANCER (2018)
SETDB1 Links the Meiotic DNA Damage Response to Sex Chromosome Silencing in Mice
Takayuki Hirota et al.
DEVELOPMENTAL CELL (2018)
Bre1-dependent H2B ubiquitination promotes homologous recombination by stimulating histone eviction at DNA breaks
Sihao Zheng et al.
NUCLEIC ACIDS RESEARCH (2018)
LncRNA ANCR promotes proliferation and radiation resistance of nasopharyngeal carcinoma by inhibiting PTEN expression
Xingkai Ma et al.
ONCOTARGETS AND THERAPY (2018)
Jumonji Inhibitors Overcome Radioresistance in Cancer through Changes in H3K4 Methylation at Double-Strand Breaks
Juan Bayo et al.
CELL REPORTS (2018)
Orchestration of H3K27 methylation: mechanisms and therapeutic implication
Mei-Ren Pan et al.
CELLULAR AND MOLECULAR LIFE SCIENCES (2018)
Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy
Lorenzo Galluzzi et al.
NATURE REVIEWS CLINICAL ONCOLOGY (2017)
Epigenetic silencing and activation of transcription: influence on the radiation sensitivity of glioma cell lines
Ali Sak et al.
INTERNATIONAL JOURNAL OF RADIATION BIOLOGY (2017)
Histone demethylase KDM5A regulates the ZMYND8-NuRD chromatin remodeler to promote DNA repair
Fade Gong et al.
JOURNAL OF CELL BIOLOGY (2017)
EZH2 promotes degradation of stalled replication forks by recruiting MUS81 through histone H3 trimethylation
Beatrice Rondinelli et al.
NATURE CELL BIOLOGY (2017)
The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity
Kenneth D. Bromberg et al.
NATURE CHEMICAL BIOLOGY (2017)
p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM
Jacob Stewart-Ornstein et al.
SCIENCE SIGNALING (2017)
Replication-Coupled Dilution of H4K20me2 Guides 53BP1 to Pre-replicative Chromatin
Stefania Pellegrino et al.
CELL REPORTS (2017)
JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity
Pier Giorgio Amendola et al.
PLOS GENETICS (2017)
p53 dynamics in response to DNA damage vary across cell lines and are shaped by efficiency of DNA repair and activity of the kinase ATM
Jacob Stewart-Ornstein et al.
SCIENCE SIGNALING (2017)
SMYD3 Promotes Homologous Recombination via Regulation of H3K4-mediated Gene Expression
Yun-Ju Chen et al.
SCIENTIFIC REPORTS (2017)
The C. elegans SET-2/SET1 histone H3 Lys4 (H3K4) methyltransferase preserves genome stability in the germline
M. Herbette et al.
DNA REPAIR (2017)
ATM-mediated KDM2A phosphorylation is required for the DNA damage repair
L-L Cao et al.
ONCOGENE (2016)
Biological function and regulation of histone and non-histone lysine methylation in response to DNA damage
Yongcan Chen et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2016)
Strong KDM4B and KDM4D Expression Associates with Radioresistance and Aggressive Phenotype in Classical Hodgkin Lymphoma
Hamid Bur et al.
ANTICANCER RESEARCH (2016)
Structure/Function Analysis of Recurrent Mutations in SETD2 Protein Reveals a Critical and Conserved Role for a SET Domain Residue in Maintaining Protein Stability and Histone H3 Lys-36 Trimethylation
Kathryn E. Hacker et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2016)
Patching Broken DNA: Nucleosome Dynamics and the Repair of DNA Breaks
Ozge Gursoy-Yuzugullu et al.
JOURNAL OF MOLECULAR BIOLOGY (2016)
Individual response to ionizing radiation
Nicolas Foray et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2016)
The many faces of histone H3K79 methylation
Zeenat Farooq et al.
MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH (2016)
53BP1 fosters fidelity of homology-directed DNA repair
Fena Ochs et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Dissecting the precise role of H3K9 methylation in crosstalk with DNA maintenance methylation in mammals
Qian Zhao et al.
NATURE COMMUNICATIONS (2016)
A cell cycle-dependent BRCA1-UHRF1 cascade regulates DNA double-strand break repair pathway choice
Haoxing Zhang et al.
NATURE COMMUNICATIONS (2016)
53BP1 fosters fidelity of homology-directed DNA repair
Fena Ochs et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2016)
Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance
Molly Gale et al.
ONCOTARGET (2016)
Histone H3 Lysine 9 Acetylation Obstructs ATM Activation and Promotes Ionizing Radiation Sensitivity in Normal Stem Cells
Barbara Meyer et al.
STEM CELL REPORTS (2016)
DnA Repair and Cytokines: TGF-β, IL-6, and Thrombopoietin as Different Biomarkers of Radioresistance
Lucia Centurione et al.
FRONTIERS IN ONCOLOGY (2016)
Depletion of Histone Demethylase Jarid1A Resulting in Histone Hyperacetylation and Radiation Sensitivity Does Not Affect DNA Double-Strand Break Repair
Corina Penterling et al.
PLOS ONE (2016)
Silencing JARID1B suppresses oncogenicity, sternness and increases radiation sensitivity in human oral carcinoma
Chun-Shu Lin et al.
CANCER LETTERS (2015)
Interaction of BARD1 and HP1 Is Required for BRCA1 Retention at Sites of DNA Damage
Wenwen Wu et al.
CANCER RESEARCH (2015)
Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination
Fade Gong et al.
GENES & DEVELOPMENT (2015)
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection
Vera Boersma et al.
NATURE (2015)
Modulation of LSD1 phosphorylation by CK2/WIP1 regulates RNF168-dependent 53BP1 recruitment in response to DNA damage
Bin Peng et al.
NUCLEIC ACIDS RESEARCH (2015)
Emodin attenuates radioresistance induced by hypoxia in HepG2 cells via the enhancement of PARP1 cleavage and inhibition of JMJD2B
Sang Youn Hwang et al.
ONCOLOGY REPORTS (2015)
The optimal utilization proportion of external beam radiotherapy in European countries: An ESTRO-HERO analysis
Josep M. Borras et al.
RADIOTHERAPY AND ONCOLOGY (2015)
Homologous Recombination and Human Health: The Roles of BRCA1, BRCA2, and Associated Proteins
Rohit Prakash et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
PHRF1 promotes genome integrity by modulating non-homologous end-joining
C-F Chang et al.
CELL DEATH & DISEASE (2015)
EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/FOXMI-Dependent Manner
Sung-Hak Kim et al.
STEM CELL REPORTS (2015)
Ionizing Radiation-Induced DNA Damage, Response, and Repair
Wil L. Santivasi et al.
ANTIOXIDANTS & REDOX SIGNALING (2014)
UTX and MLL4 Coordinately Regulate Transcriptional Programs for Cell Proliferation and Invasiveness in Breast Cancer Cells
Jae-Hwan Kim et al.
CANCER RESEARCH (2014)
Inefficient Double-Strand Break Repair in Murine Rod Photoreceptors with Inverted Heterochromatin Organization
Antonia Frohns et al.
CURRENT BIOLOGY (2014)
Polycomb-Dependent H3K27me1 and H3K27me2 Regulate Active Transcription and Enhancer Fidelity
Karin J. Ferrari et al.
MOLECULAR CELL (2014)
Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks
Francois Aymard et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2014)
p53 promotes repair of heterochromatin DNA by regulating JMJD2b and SUV39H1 expression
H. Zheng et al.
ONCOGENE (2014)
Aberrant histone methylation and the effect of Suv39H1 siRNA on gastric carcinoma
Lisheng Cai et al.
ONCOLOGY REPORTS (2014)
The Histone Lysine Demethylase JMJD3/KDM6B Is Recruited to p53 Bound Promoters and Enhancer Elements in a p53 Dependent Manner
Kristine Williams et al.
PLOS ONE (2014)
DNA double-strand breaks promote methylation of histone H3 on lysine 9 and transient formation of repressive chromatin
Marina K. Ayrapetov et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Histone demethylase KDM5B is a key regulator of genome stability
Xin Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Sources of DNA Double-Strand Breaks and Models of Recombinational DNA Repair
Anuja Mehta et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2014)
Concerted Activities of Distinct H4K20 Methyltransferases at DNA Double-Strand Breaks Regulate 53BP1 Nucleation and NHEJ-Directed Repair
Creighton T. Tuzon et al.
CELL REPORTS (2014)
SETD2-Dependent Histone H3K36 Trimethylation Is Required for Homologous Recombination Repair and Genome Stability
Sophia X. Pfister et al.
CELL REPORTS (2014)
SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint
Silvia Carvalho et al.
ELIFE (2014)
KDM4/JMJD2 Histone Demethylases: Epigenetic Regulators in Cancer Cells
William L. Berry et al.
CANCER RESEARCH (2013)
Chromatin Remodeling at DNA Double-Strand Breaks
Brendan D. Price et al.
CELL (2013)
The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through Its Interaction with MutSα
Feng Li et al.
CELL (2013)
Polycomb repressive complex 2 contributes to DNA double-strand break repair
Stuart Campbell et al.
CELL CYCLE (2013)
Detection and Repair of Ionizing Radiation-Induced DNA Double Strand Breaks: New Developments in Nonhomologous End Joining
Chen Wang et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2013)
Kdm4b Histone Demethylase Is a DNA Damage Response Protein and Confers a Survival Advantage following γ-Irradiation
Leah C. Young et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2013)
The histone demethylase LSD1/KDM1A promotes the DNA damage response
Nima Mosammaparast et al.
JOURNAL OF CELL BIOLOGY (2013)
A Method for Systematic Mapping of Protein Lysine Methylation Identifies Functions for HP1β in DNA Damage Response
Huadong Liu et al.
MOLECULAR CELL (2013)
Acetylation limits 53BP1 association with damaged chromatin to promote homologous recombination
Jiangbo Tang et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2013)
Inhibition of EZH2 suppresses self-renewal and induces radiation sensitivity in atypical rhabdoid teratoid tumor cells
Irina Alimova et al.
NEURO-ONCOLOGY (2013)
Drosophila UTX Coordinates with p53 to Regulate ku80 Expression in Response to DNA Damage
Chengwan Zhang et al.
PLOS ONE (2013)
53BP1 Regulates DSB Repair Using Rif1 to Control 5′ End Resection
Michal Zimmermann et al.
SCIENCE (2013)
Repair of Strand Breaks by Homologous Recombination
Maria Jasin et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2013)
Histone Methyltransferase DOT1L Drives Recovery of Gene Expression after a Genotoxic Attack
Valentyn Oksenych et al.
PLOS GENETICS (2013)
Double strand breaks Hurdles for RNA polymerase II transcription?
Tibor Pankotai et al.
TRANSCRIPTION-AUSTIN (2013)
Histone methylation: a dynamic mark in health, disease and inheritance
Eric L. Greer et al.
NATURE REVIEWS GENETICS (2012)
DNAPKcs-dependent arrest of RNA polymerase II transcription in the presence of DNA breaks
Tibor Pankotai et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
LEDGF (p75) promotes DNA-end resection and homologous recombination
Mads Daugaard et al.
NATURE STRUCTURAL & MOLECULAR BIOLOGY (2012)
SPOC1 modulates DNA repair by regulating key determinants of chromatin compaction and DNA damage response
Andreas Mund et al.
NUCLEIC ACIDS RESEARCH (2012)
Chk1 phosphorylation of Metnase enhances DNA repair but inhibits replication fork restart
R. Hromas et al.
ONCOGENE (2012)
BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair
Amitabh V. Nimonkar et al.
GENES & DEVELOPMENT (2011)
H3K27me3 Protein Is a Promising Predictive Biomarker of Patients' Survival and Chemoradioresistance in Human Nasopharyngeal Carcinoma
Mu-Yan Cai et al.
MOLECULAR MEDICINE (2011)
MMSET regulates histone H4K20 methylation and 53BP1 accumulation at DNA damage sites
Huadong Pei et al.
NATURE (2011)
The Polycomb complex PRC2 and its mark in life
Raphael Margueron et al.
NATURE (2011)
Methylation of histone H3 lysine 36 enhances DNA repair by nonhomologous end-joining
Sheema Fnu et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
ATM-Dependent Chromatin Changes Silence Transcription In cis to DNA Double-Strand Breaks
Niraj M. Shanbhag et al.
CELL (2010)
Acetylation of H2AX on lysine 36 plays a key role in the DNA double-strand break repair pathway
Xiaofeng Jiang et al.
FEBS LETTERS (2010)
A chromatin localization screen reveals poly (ADP ribose)-regulated recruitment of the repressive polycomb and NuRD complexes to sites of DNA damage
Danny M. Chou et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2010)
Deficiency in Bre1 Impairs Homologous Recombination Repair and Cell Cycle Checkpoint Response to Radiation Damage in Mammalian Cells
Sophia B. Chernikova et al.
RADIATION RESEARCH (2010)
Repair of ionizing radiation-induced DNA double-strand breaks by non-homologous end-joining
Brandi L. Mahaney et al.
BIOCHEMICAL JOURNAL (2009)
Global reduction of the epigenetic H3K79 methylation mark and increased chromosomal instability in CALM-AF10-positive leukemias
Yi-Hui Lin et al.
BLOOD (2009)
Prognostic impact of H3K27me3 expression on locoregional progression after chemoradiotherapy in esophageal squamous cell carcinoma
Li-Ru He et al.
BMC CANCER (2009)
Embryonic stem cells lacking the epigenetic regulator Cfp1 are hypersensitive to DNA-damaging agents and exhibit decreased Ape1/Ref-1 protein expression and endonuclease activity
Courtney M. Tate et al.
DNA REPAIR (2009)
Histone H3 methylation links DNA damage detection to activation of the tumour suppressor Tip60
Yingli Sun et al.
NATURE CELL BIOLOGY (2009)
Histone H3 Lys79 methylation is required for efficient nucleotide excision repair in a silenced locus of Saccharomyces cerevisiae
Shubho Chaudhuri et al.
NUCLEIC ACIDS RESEARCH (2009)
Sgs1 helicase and two nucleases Dna2 and Exo1 resect DNA double-strand break ends
Zhu Zhu et al.
CELL (2008)
Role of Dot1 in the response to alkylating DNA damage in Saccharomyces cerevisiae:: Regulation of DNA damage tolerance by the error-prone polymerases Po1ζ/Rev1
Francisco Conde et al.
GENETICS (2008)
Preferential dimethylation of histone H4 lysine 20 by Suv4-20
Hongbo Yang et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2008)
HP1-β mobilization promotes chromatin changes that initiate the DNA damage response
Nabieh Ayoub et al.
NATURE (2008)
Distinct roles of chromatin-associated proteins MDC1 and 53BP1 in mammalian double-strand break repair
Anyong Xie et al.
MOLECULAR CELL (2007)
Human CtIP promotes DNA end resection
Alessandro A. Sartori et al.
NATURE (2007)
DNA damage-dependent acetylation and ubiquitination of H2AX enhances chromatin dynamics
Tsuyoshi Ikura et al.
MOLECULAR AND CELLULAR BIOLOGY (2007)
Pharmacologic disruption of polycomb-repressive complex 2-mediated gene repression selectively induces apoptosis in cancer cells
Jing Tan et al.
GENES & DEVELOPMENT (2007)
Chromatin modifications and their function
Tony Kouzarides
CELL (2007)
CpG-binding protein (CXXC finger protein 1) is a component of the mammalian set1 histone H3-Lys4 methyltransferase complex, the analogue of the yeast Set1/COMPASS complex
JH Lee et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair
SH Lee et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
The diverse functions of histone lysine methylation
C Martin et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2005)
Role of Dot1-dependent histone H3 methylation in G1 and S phase DNA damage checkpoint functions of Rad9
R Wysocki et al.
MOLECULAR AND CELLULAR BIOLOGY (2005)
A role for the Tip60 histone acetyltransferase in the acetylation and activation of ATM
YL Sun et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2005)
Methylated lysine 79 of histone H3 targets 53BP1 to DNA double-strand breaks
Y Huyen et al.
NATURE (2004)
Mechanisms of human DNA repair: an update
M Christmann et al.
TOXICOLOGY (2003)
Roles of BRCA1 and BRCA2 in homologous recombination, DNA replication fidelity and the cellular response to ionizing radiation
SN Powell et al.
ONCOGENE (2003)
The role of p53 in determining sensitivity to radiotherapy
AV Gudkov et al.
NATURE REVIEWS CANCER (2003)
53BP1, a mediator of the DNA damage checkpoint
B Wang et al.
SCIENCE (2002)
Hairpin opening and overhang processing by an Artemis/DNA-dependent protein kinase complex in nonhomologous end joining and V(D)J recombination
YM Ma et al.
CELL (2002)