4.6 Article

From iPS Cells to Rodents and Nonhuman Primates: Filling Gaps in Modeling Parkinson's Disease

Related references

Note: Only part of the references are listed.
Article Multidisciplinary Sciences

The process of Lewy body formation, rather than simply α-synuclein fibrillization, is one of the major drivers of neurodegeneration

Anne-Laure Mahul-Mellier et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)

Review Clinical Neurology

Nosology and Phenomenology of Psychosis in Movement Disorders

Malco Rossi et al.

MOVEMENT DISORDERS CLINICAL PRACTICE (2020)

Article Neurosciences

Animal Models of Parkinson's Disease: Are They Useful or Not?

Roger A. Barker et al.

JOURNAL OF PARKINSONS DISEASE (2020)

Review Clinical Neurology

Autonomic dysfunction in Parkinson disease and animal models

Jeanette M. Metzger et al.

CLINICAL AUTONOMIC RESEARCH (2019)

Review Clinical Neurology

Physiological changes in neurodegeneration - mechanistic insights and clinical utility

Rebekah M. Ahmed et al.

NATURE REVIEWS NEUROLOGY (2018)

Article Multidisciplinary Sciences

Assembly of functionally integrated human forebrain spheroids

Fikri Birey et al.

NATURE (2017)

Article Multidisciplinary Sciences

Cell diversity and network dynamics in photosensitive human brain organoids

Giorgia Quadrato et al.

NATURE (2017)

Article Biotechnology & Applied Microbiology

Guided self-organization and cortical plate formation in human brain organoids

Madeline A. Lancaster et al.

NATURE BIOTECHNOLOGY (2017)

Review Neurosciences

Selective neuronal vulnerability in Parkinson disease

D. James Surmeier et al.

NATURE REVIEWS NEUROSCIENCE (2017)

Article Cell & Tissue Engineering

Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells

Anna S. Monzel et al.

STEM CELL REPORTS (2017)

Article Biochemistry & Molecular Biology

Brain-Region-Specific Organoids Using Mini-bioreactors for Modeling ZIKV Exposure

Xuyu Qian et al.

Review Cell & Tissue Engineering

Genome Editing in Human Pluripotent Stem Cells: Approaches, Pitfalls, and Solutions

William T. Hendriks et al.

CELL STEM CELL (2016)

Article Neurosciences

Mutant Alpha-Synuclein Causes Age-Dependent Neuropathology in Monkey Brain

Weili Yang et al.

JOURNAL OF NEUROSCIENCE (2015)

Article Biochemical Research Methods

Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture

Anca M. Pasca et al.

NATURE METHODS (2015)

Article Multidisciplinary Sciences

Human cerebral organoids recapitulate gene expression programs of fetal neocortex development

J. Gray Camp et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)

Review Neurosciences

Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease

Matthieu F. Bastide et al.

PROGRESS IN NEUROBIOLOGY (2015)

Article Multidisciplinary Sciences

Long-term maintenance of human induced pluripotent stem cells by automated cell culture system

Shuhei Konagaya et al.

SCIENTIFIC REPORTS (2015)

Article Neurosciences

f Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression

Mathieu Bourdenx et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2015)

Article Geriatrics & Gerontology

Astrocytosis in parkinsonism: considering tripartite striatal synapses in physiopathology?

Giselle Charron et al.

FRONTIERS IN AGING NEUROSCIENCE (2014)

Review Cell & Tissue Engineering

Stem Cell Applications in Regenerative Medicine for Neurological Disorders

Shih-Ping Liu et al.

CELL TRANSPLANTATION (2013)

Article Neurosciences

Microglia Regulate the Number of Neural Precursor Cells in the Developing Cerebral Cortex

Christopher L. Cunningham et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Neurosciences

Evolutionarily Novel Functional Networks in the Human Brain?

Dante Mantini et al.

JOURNAL OF NEUROSCIENCE (2013)

Article Multidisciplinary Sciences

Cerebral organoids model human brain development and microcephaly

Madeline A. Lancaster et al.

NATURE (2013)

Article Multidisciplinary Sciences

Self-organization of axial polarity, inside-out layer pattern, and species-specific progenitor dynamics in human ES cell-derived neocortex

Taisuke Kadoshima et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)

Review Neurosciences

Animal models of the non-motor features of Parkinson's disease

Kimberly McDowell et al.

NEUROBIOLOGY OF DISEASE (2012)

Article Multidisciplinary Sciences

Systemic scAAV9 variant mediates brain transduction in newborn rhesus macaques

Benjamin Dehay et al.

SCIENTIFIC REPORTS (2012)

Article Medicine, Research & Experimental

Modeling Parkinson's Disease in Primates: The MPTP Model

Gregory Porras et al.

COLD SPRING HARBOR PERSPECTIVES IN MEDICINE (2012)

Review Clinical Neurology

A Tale on Animal Models of Parkinson's Disease

Erwan Bezard et al.

MOVEMENT DISORDERS (2011)

Article Multidisciplinary Sciences

Self-formation of functional adenohypophysis in three-dimensional culture

Hidetaka Suga et al.

NATURE (2011)

Article Biotechnology & Applied Microbiology

Rescue of the spinal muscular atrophy phenotype in a mouse model by early postnatal delivery of SMN

Kevin D. Foust et al.

NATURE BIOTECHNOLOGY (2010)

Article Neurosciences

Neurovascular Congruence during Cerebral Cortical Development

Daniel Stubbs et al.

CEREBRAL CORTEX (2009)

Article Neurosciences

A Stem Cell Niche for Intermediate Progenitor Cells of the Embryonic Cortex

Ashkan Javaherian et al.

CEREBRAL CORTEX (2009)

Article Biotechnology & Applied Microbiology

Highly efficient neural conversion of human ES and iPS cells by dual inhibition of SMAD signaling

Stuart M. Chambers et al.

NATURE BIOTECHNOLOGY (2009)

Article Multidisciplinary Sciences

Towards a transgenic model of Huntington's disease in a non-human primate

Shang-Hsun Yang et al.

NATURE (2008)

Article Biochemical Research Methods

Induction of pluripotent stem cells from fibroblast cultures

Kazutoshi Takahashi et al.

NATURE PROTOCOLS (2007)

Article Biochemistry & Molecular Biology

P25α stimulates a-synuclein aggregation and is co-localized with aggregated α-synuclein in α-synucleinopathies

E Lindersson et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Multidisciplinary Sciences

Derivation of midbrain dopamine neurons from human embryonic stem cells

AL Perrier et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)

Article Multidisciplinary Sciences

Yeast cells provide insight into alpha-synuclein biology and pathobiology

TF Outeiro et al.

SCIENCE (2003)

Article Multidisciplinary Sciences

Nigrostriatal α-synucleinopathy induced by viral vector-mediated overexpression of human α-synuclein:: A new primate model of Parkinson's disease

D Kirik et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)

Review Geriatrics & Gerontology

Staging of brain pathology related to sporadic Parkinson's disease

H Braak et al.

NEUROBIOLOGY OF AGING (2003)

Review Neurosciences

Animal models of neurological deficits: how relevant is the rat?

MA Cenci et al.

NATURE REVIEWS NEUROSCIENCE (2002)

Article Multidisciplinary Sciences

Transgenic monkeys produced by retroviral gene transfer into mature oocytes

AWS Chan et al.

SCIENCE (2001)