Related references
Note: Only part of the references are listed.Anti-angiogenic Agents: A Review on Vascular Endothelial Growth Factor Receptor-2 (VEGFR-2) Inhibitors
Kang Cheng et al.
CURRENT MEDICINAL CHEMISTRY (2021)
Understanding the role of integrins in breast cancer invasion, metastasis, angiogenesis, and drug resistance
Hassan Yousefi et al.
ONCOGENE (2021)
Thiazolidine-2,4-dione-based irreversible allosteric IKK-β kinase inhibitors: Optimization into in vivo active anti-inflammatory agents
Ahmed Elkamhawy et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2020)
The tubulin code and its role in controlling microtubule properties and functions
Carsten Janke et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2020)
Sulfonamide-based 4-anilinoquinoline derivatives as novel dual Aurora kinase (AURKA/B) inhibitors: Synthesis, biological evaluation and in silico insights
Mohammad M. Al-Sanea et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2020)
Exploring the multiple binding modes of inhibitors to carbonic anhydrases for novel drug discovery
Claudiu T. Supuran
EXPERT OPINION ON DRUG DISCOVERY (2020)
A Review on Recent Advances in Nitrogen-Containing Molecules and Their Biological Applications
Nagaraju Kerru et al.
MOLECULES (2020)
Hypoxia-induced alternative splicing: the 11th Hallmark of Cancer
Antonietta Rosella Farina et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
Dynamic and asymmetric fluctuations in the microtubule wall captured by high-resolution cryoelectron microscopy
Garrett E. Debs et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
An inhibitor of endothelial ETS transcription factors promotes physiologic and therapeutic vessel regression
Christopher M. Schafer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2020)
The Mechanism of Tubulin Assembly into Microtubules: Insights from Structural Studies
Marcel Knossow et al.
iScience (2020)
Discovery ofN-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide: a novel, selective, and competitive indole-based lead inhibitor for human monoamine oxidase B
Ahmed Elkamhawy et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2020)
A Review on the Antitumor Activity of Various Nitrogenous-based Hetero-cyclic Compounds as NSCLC Inhibitors
Jia-Chun Liu et al.
MINI-REVIEWS IN MEDICINAL CHEMISTRY (2019)
Matrix metalloproteinases participation in the metastatic process and their diagnostic and therapeutic applications in cancer
Georgina Gonzalez-Avila et al.
CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY (2019)
Integrins as biomechanical sensors of the microenvironment
Jenny Z. Kechagia et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2019)
Multi-target design strategies for the improved treatment of Alzheimer's disease
Pengfei Zhang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2019)
Optimization study towards more potent thiazolidine-2,4-dione IKK-β modulator: Synthesis, biological evaluation and in silico docking simulation
Ahmed Elkamhawy et al.
BIOORGANIC CHEMISTRY (2019)
EG-VEGF silencing inhibits cell proliferation and promotes cell apoptosis in pancreatic carcinoma via PI3K/AKT/mTOR signaling pathway
Xiaogang Yan et al.
BIOMEDICINE & PHARMACOTHERAPY (2019)
Synthesis and biological evaluation of novel 3-(quinolin-4-ylamino)benzenesulfonamidesAQ3 as carbonic anhydrase isoforms I and II inhibitors
Mohammad M. Al-Sanea et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2019)
Mechanisms of VEGF (Vascular Endothelial Growth Factor) Inhibitor-Associated Hypertension and Vascular Disease
Arvind K. Pandey et al.
HYPERTENSION (2018)
Angiogenesis biomarkers and their targeting ligands as potential targets for tumor angiogenesis
Mohammad Mashreghi et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2018)
Hypoxia-inducible factor-1 (HIF-1) inhibitors from the last decade (2007 to 2016): A structure-activity relationship perspective
Deepak Bhattarai et al.
MEDICINAL RESEARCH REVIEWS (2018)
Repositioning of the antipsychotic trifluoperazine: Synthesis, biological evaluation and in silico study of trifluoperazine analogs as anti-glioblastoma agents
Seokmin Kang et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2018)
Sulfonamide inhibitors: a patent review 2013-present
Ilhami Gulcin et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2018)
Inhibition studies on a panel of human carbonic anhydrases with N1-substituted secondary sulfonamides incorporating thiazolinone or imidazolone-indole tails
Fadi M. Awadallah et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2018)
From Oxiranes to Oligomers: Architectures of US FDA Approved Pharmaceuticals Containing Oxygen Heterocycles
Michael D. Delost et al.
JOURNAL OF MEDICINAL CHEMISTRY (2018)
Coming into Focus: Mechanisms of Microtubule Minus-End Organization
Maud Martin et al.
TRENDS IN CELL BIOLOGY (2018)
Anti-Angiogenics: Current Situation and Future Perspectives
Katja Zirlik et al.
ONCOLOGY RESEARCH AND TREATMENT (2018)
Tumour microenvironment and metabolic plasticity in cancer and cancer stem cells: Perspectives on metabolic and immune regulatory signatures in chemoresistant ovarian cancer stem cells
Nuzhat Ahmed et al.
SEMINARS IN CANCER BIOLOGY (2018)
Structure and function of vascular endothelial growth factor and its receptor system
Seong Ah Park et al.
BMB REPORTS (2018)
Every step of the way: integrins in cancer progression and metastasis
Hellyeh Hamidi et al.
NATURE REVIEWS CANCER (2018)
Microtubule destabilising agents: far more than just antimitotic anticancer drugs
Darcy Bates et al.
BRITISH JOURNAL OF CLINICAL PHARMACOLOGY (2017)
Structure-activity relationship (SAR) study and design strategies of nitrogen-containing heterocyclic moieties for their anticancer activities
Jawaid Akhtar et al.
EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY (2017)
VEGFR-2 inhibitors and the therapeutic applications thereof: a patent review (2012-2016)
Fan-Wei Peng et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2017)
Tumor angiogenesis revisited: Regulators and clinical implications
Roberto Ronca et al.
MEDICINAL RESEARCH REVIEWS (2017)
Tubulin isoform composition tunes microtubule dynamics
Annapurna Vemu et al.
MOLECULAR BIOLOGY OF THE CELL (2017)
Anti-angiogenic agents for the treatment of solid tumors: Potential pathways, therapy and current strategies - A review
Ahmed M. Al-Abd et al.
JOURNAL OF ADVANCED RESEARCH (2017)
Transport of drugs from blood vessels to tumour tissue
Mark W. Dewhirst et al.
NATURE REVIEWS CANCER (2017)
Tumor angiogenesis and vascular normalization: alternative therapeutic targets
Claire Viallard et al.
ANGIOGENESIS (2017)
Hit discovery of 4-amino-N-(4-(3-(trifluoromethyl)phenoxy)pyrimidin-5-yl)benzamide: A novel EGFR inhibitor from a designed small library
Ahmed Elkamhawy et al.
BIOORGANIC CHEMISTRY (2017)
CXCL1 Is Critical for Premetastatic Niche Formation and Metastasis in Colorectal Cancer
Dingzhi Wang et al.
CANCER RESEARCH (2017)
Examining the structure-activity relationship of benzopyran-based inhibitors of the hypoxia inducible factor-1 pathway
Jalisa Ferguson et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2017)
Discovery of a broad spectrum antiproliferative agent with selectivity for DDR1 kinase: cell line-based assay, kinase panel, molecular docking, and toxicity studies
Ahmed Elkamhawy et al.
JOURNAL OF ENZYME INHIBITION AND MEDICINAL CHEMISTRY (2016)
Paclitaxel-Paclitaxel Prodrug Nanoassembly as a Versatile Nanoplatform for Combinational Cancer Therapy
Xiangfei Han et al.
ACS APPLIED MATERIALS & INTERFACES (2016)
A BOILED-Egg To Predict Gastrointestinal Absorption and Brain Penetration of Small Molecules
Antoine Daina et al.
CHEMMEDCHEM (2016)
Angiogenesis inhibitors as therapeutic agents in cancer: Challenges and future directions
Zhexuan Lin et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2016)
Mechanosensing in cell-matrix adhesions - Converting tension into chemical signals
Vesa P. Hytonen et al.
EXPERIMENTAL CELL RESEARCH (2016)
Current Advances of Tubulin Inhibitors in Nanoparticle Drug Delivery and Vascular Disruption/Angiogenesis
Souvik Banerjee et al.
MOLECULES (2016)
VEGF-A/Notch-Induced Podosomes Proteolyse Basement Membrane Collagen-IV during Retinal Sprouting Angiogenesis
Pirjo Spuul et al.
CELL REPORTS (2016)
Research advances on structure and biological functions of integrins
Li Pan et al.
SPRINGERPLUS (2016)
Global Cancer Statistics, 2012
Lindsey A. Torre et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2015)
The Warburg effect in tumor progression: Mitochondrial oxidative metabolism as an anti-metastasis mechanism
Jianrong Lu et al.
CANCER LETTERS (2015)
Panobinostat: First Global Approval
Karly P. Garnock-Jones
DRUGS (2015)
Angiogenin promotes tumoral growth and angiogenesis by regulating matrix metallopeptidase-2 expression via the ERK1/2 pathway
M. Miyake et al.
ONCOGENE (2015)
VEGF-Mediated Angiogenesis Links EMT-Induced Cancer Stemness to Tumor Initiation
Anna Fantozzi et al.
CANCER RESEARCH (2014)
Remodelling the extracellular matrix in development and disease
Caroline Bonnans et al.
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2014)
Pazopanib versus Sunitinib in Metastatic Renal-Cell Carcinoma
Robert J. Motzer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2013)
'Go or Grow': the key to the emergence of invasion in tumour progression?
H. Hatzikirou et al.
MATHEMATICAL MEDICINE AND BIOLOGY-A JOURNAL OF THE IMA (2012)
Sulfonamides as a new scaffold for hypoxia inducible factor pathway inhibitors
Chalet Tan et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2011)
Global Cancer Statistics
Ahmedin Jemal et al.
CA-A CANCER JOURNAL FOR CLINICIANS (2011)
Roles of matrix metalloproteinases in cancer progression and their pharmacological targeting
Chrisostomi Gialeli et al.
FEBS JOURNAL (2011)
Computer-aided drug design and ADMET predictions for identification and evaluation of novel potential farnesyltransferase inhibitors in cancer therapy
Carlos Henrique Tomich de Paula da Silva et al.
JOURNAL OF MOLECULAR GRAPHICS & MODELLING (2010)
Targeting Angiogenesis with Multitargeted Tyrosine Kinase Inhibitors in the Treatment of Non-Small Cell Lung Cancer
Giorgio Scagliotti et al.
ONCOLOGIST (2010)
Tumor Angiogenesis: Insights and Innovations
Fernando Nussenbaum et al.
JOURNAL OF ONCOLOGY (2010)
Targeting the tumour vasculature: insights from physiological angiogenesis
Alicia S. Chung et al.
NATURE REVIEWS CANCER (2010)
Integrin α2 Mediates Selective Metastasis to the Liver
Kiyoshi Yoshimura et al.
CANCER RESEARCH (2009)
Actin and microtubule cytoskeleton interactions
Jan Petrasek et al.
CURRENT OPINION IN PLANT BIOLOGY (2009)
Design, Structure-Activity Relationships and in Vivo Characterization of 4-Amino-3-benzimidazol-2-ylhydroquinolin-2-ones: A Novel Class of Receptor Tyrosine Kinase Inhibitors
Paul A. Renhowe et al.
JOURNAL OF MEDICINAL CHEMISTRY (2009)
The angiogenic switch in carcinogenesis
Vanessa Baeriswyl et al.
SEMINARS IN CANCER BIOLOGY (2009)
Primary and Secondary Kinase Genotypes Correlate With the Biological and Clinical Activity of Sunitinib in Imatinib-Resistant Gastrointestinal Stromal Tumor
Michael C. Heinrich et al.
JOURNAL OF CLINICAL ONCOLOGY (2008)
Evaluation of the tubulin-bound paclitaxel conformation:: Synthesis, biology, and SAR studies of C-4 to C-3′ bridged paclitaxel analogues
Thota Ganesh et al.
JOURNAL OF MEDICINAL CHEMISTRY (2007)
Targeting Microtubules to inhibit angiogenesis and disrupt tumour vasculature: Implications for cancer treatment
Eddy Pasquier et al.
CURRENT CANCER DRUG TARGETS (2007)
Understanding the biology of angiogenesis: Review of the most important molecular mechanisms
Zaher K. Otrock et al.
BLOOD CELLS MOLECULES AND DISEASES (2007)
Synthesis and structure-activity relationships of β- and α-piperidine sulfone hydroxamic acid matrix metalloproteinase inhibitors with oral antitumor efficacy
DP Becker et al.
JOURNAL OF MEDICINAL CHEMISTRY (2005)
Molecular regulation of the VEGF family - inducers of angiogenesis and lymphangiogenesis
BK McColl et al.
APMIS (2004)
Hypoxia-inducible factors and hypoxic cell death in tumour physiology
AL Bacon et al.
ANNALS OF MEDICINE (2004)
Microtubule-interacting drugs for cancer treatment
PM Checchi et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2003)
Solution structure and backbone dynamics of the catalytic domain of matrix metalloproteinase-2 complexed with a hydroxamic acid inhibitor
YQ Feng et al.
BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS (2002)
Novel sulphonamide derivatives for the treatment of cancer
T Owa et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2000)
Cell signaling by receptor tyrosine kinases
J Schlessinger
CELL (2000)