Related references
Note: Only part of the references are listed.Rilpivirine plus cobicistat-boosted darunavir as a two-drug switch regimen in HIV-infected, virologically suppressed subjects on steady standard three-drug therapy: a randomized, controlled, non-inferiority trial (PROBE2)
F. Maggiolo et al.
JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY (2020)
Peptides Mimicking the β7/β8 Loop of HIV-1 Reverse Transcriptase p51 as Hotspot-Targeted Dimerization Inhibitors
Pedro A. Sanchez-Murcia et al.
ACS MEDICINAL CHEMISTRY LETTERS (2020)
Recent discoveries in HIV-1 reverse transcriptase inhibitors
Shuang-Xi Gu et al.
CURRENT OPINION IN PHARMACOLOGY (2020)
Exploiting the Tolerant Region I of the Non-Nucleoside Reverse Transcriptase Inhibitor (NNRTI) Binding Pocket: Discovery of Potent Diarylpyrimidine-Typed HIV-1 NNRTIs against Wild-Type and E138K Mutant Virus with Significantly Improved Water Solubility and Favorable Safety Profiles
Boshi Huang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2019)
Role of the IgE variable heavy chain in FcεRIα and superantigen binding in allergy and immunotherapy
Wai-Heng Lua et al.
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY (2019)
Perspective: The promises of a holistic view of proteins-impact on antibody engineering and drug discovery
Ser-Xian Phua et al.
BIOSCIENCE REPORTS (2019)
Modeling the full length HIV-1 Gag polyprotein reveals the role of its p6 subunit in viral maturation and the effect of non-cleavage site mutations in protease drug resistance
Chinh Tran-To Su et al.
JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2018)
A computational study for rational HIV-1 non-nucleoside reverse transcriptase inhibitor selection and the discovery of novel allosteric pockets for inhibitor design
Ron Zhi-Hui Chiang et al.
BIOSCIENCE REPORTS (2018)
Current insights into anti-HIV drug discovery and development: a review of recent patent literature (2014-2017)
Xiaofang Zuo et al.
EXPERT OPINION ON THERAPEUTIC PATENTS (2018)
The effects of Antibody Engineering CH and CL in Trastuzumab and Pertuzumab recombinant models: Impact on antibody production and antigen-binding
Wai-Heng Lua et al.
SCIENTIFIC REPORTS (2018)
Effect of VH-VL Families in Pertuzumab and Trastuzumab Recombinant Production, Her2 and FcγIIA Binding
Wei-Li Ling et al.
FRONTIERS IN IMMUNOLOGY (2018)
Allosteric Effects between the Antibody Constant and Variable Regions: A Study of IgA Fc Mutations on Antigen Binding
Chinh Tran-To Su et al.
ANTIBODIES (2018)
CHARMM36m: an improved force field for folded and intrinsically disordered proteins
Jing Huang et al.
NATURE METHODS (2017)
The role of Antibody Vκ Framework 3 region towards Antigen binding: Effects on recombinant production and Protein L binding
Chinh Tran-To Su et al.
SCIENTIFIC REPORTS (2017)
Off-Target Effects of Drugs that Disrupt Human Mitochondrial DNA Maintenance
Matthew J. Young
FRONTIERS IN MOLECULAR BIOSCIENCES (2017)
Anti-HIV Drug Discovery and Development: Current Innovations and Future Trends
Peng Zhan et al.
JOURNAL OF MEDICINAL CHEMISTRY (2016)
Structural analyses of 2015-updated drug-resistant mutations in HIV-1 protease: an implication of protease inhibitor cross-resistance
Chinh Tran-To Su et al.
BMC BIOINFORMATICS (2016)
g_mmpbsa-A GROMACS Tool for High-Throughput MM-PBSA Calculations
Rashmi Kumari et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2014)
Old Dogs with New Tricks: exploiting alternative mechanisms of action and new drug design strategies for clinically validated HIV targets
Dongwei Kang et al.
MOLECULAR BIOSYSTEMS (2014)
ConSurf: Using Evolutionary Data to Raise Testable Hypotheses about Protein Function
Gershon Celniker et al.
ISRAEL JOURNAL OF CHEMISTRY (2013)
Fiji: an open-source platform for biological-image analysis
Johannes Schindelin et al.
NATURE METHODS (2012)
Comparison of end-point continuum-solvation methods for the calculation of protein-ligand binding free energies
Samuel Genheden et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2012)
Allosteric Suppression of HIV-1 Reverse Transcriptase Structural Dynamics upon Inhibitor Binding
James M. Seckler et al.
BIOPHYSICAL JOURNAL (2011)
LigPlot+: Multiple Ligand-Protein Interaction Diagrams for Drug Discovery
Roman A. Laskowski et al.
JOURNAL OF CHEMICAL INFORMATION AND MODELING (2011)
Virtual screening using molecular simulations
Tianyi Yang et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2011)
Fifteen years of HIV Protease Inhibitors: raising the barrier to resistance
Annemarie M. J. Wensing et al.
ANTIVIRAL RESEARCH (2010)
Software News and Update AutoDock Vina: Improving the Speed and Accuracy of Docking with a New Scoring Function, Efficient Optimization, and Multithreading
Oleg Trott et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2010)
CHARMM General Force Field: A Force Field for Drug-Like Molecules Compatible with the CHARMM All-Atom Additive Biological Force Fields
K. Vanommeslaeghe et al.
JOURNAL OF COMPUTATIONAL CHEMISTRY (2010)
ConSurf 2010: calculating evolutionary conservation in sequence and structure of proteins and nucleic acids
Haim Ashkenazy et al.
NUCLEIC ACIDS RESEARCH (2010)
Structure and Function of HIV-1 Reverse Transcriptase: Molecular Mechanisms of Polymerization and Inhibition
Stefan G. Sarafianos et al.
JOURNAL OF MOLECULAR BIOLOGY (2009)
HIV Entry Inhibitors and Their Potential in HIV Therapy
Keduo Qian et al.
MEDICINAL RESEARCH REVIEWS (2009)
The Hill equation: a review of its capabilities in pharmacological modelling
Sylvain Goutelle et al.
FUNDAMENTAL & CLINICAL PHARMACOLOGY (2008)
Probing nonnucleoside inhibitor-induced active-site distortion in HIV-1 reverse transcriptase by transient kinetic analyses
Qing Xia et al.
PROTEIN SCIENCE (2007)
HIV chemokine receptor inhibitors as novel anti-HIV drugs
K Princen et al.
CYTOKINE & GROWTH FACTOR REVIEWS (2005)
High sequence conservation of human immunodeficiency virus-type 1 reverse transcriptase under drug pressure despite the continuous appearance of mutations
F Ceccherini-Silberstein et al.
JOURNAL OF VIROLOGY (2005)
The N137 and P140 amino acids in the p51 and the P95 amino acid in the p66 subunit of human immunodeficiency virus type I (HIV-1) reverse transcriptase are instrumental to maintain catalytic activity and to design new classes of anti-HIV-1 drugs
J Auwerx et al.
FEBS LETTERS (2005)
Integrase inhibitors to treat HIV/AIDS
Y Pommier et al.
NATURE REVIEWS DRUG DISCOVERY (2005)
What are the dielectric constants of proteins and how to validate electrostatic models?
CN Schutz et al.
PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS (2001)
Control selection for RNA quantitation
T Suzuki et al.
BIOTECHNIQUES (2000)