4.4 Review

Photobiomodulation therapy as a high potential treatment modality for COVID-19

Journal

LASERS IN MEDICAL SCIENCE
Volume 36, Issue 5, Pages 935-938

Publisher

SPRINGER LONDON LTD
DOI: 10.1007/s10103-020-03206-9

Keywords

Coronavirus; Low-level light therapy; Respiratory distress syndrome; adult; Inflammation; COVID-19; Photobiomodulation

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COVID-19 has become a global concern, with patients showing different symptoms based on disease severity. While the host immune system can successfully eliminate the virus in mild cases, it may lead to acute respiratory distress syndrome in severe cases. Photobiomodulation has shown promising results in reducing acute pulmonary inflammation and may be an effective treatment modality for managing ARDS in COVID-19 patients.
COVID-19 is now a worldwide concern, causing an unprecedented pandemic. The infected cases show different symptoms based on the severity of the disease. In asymptomatic and non-severe symptomatic cases, the host immune system can successfully eliminate the virus and its effects. In severe cases, however, immune system impairment causes cytokine release syndrome which eventually leads to acute respiratory distress syndrome (ARDS). In recent years, photobiomodulation (PBM) has shown promising results in reducing acute pulmonary inflammation. Considering the high potential impact of PBM on immune responses, we hypothesized that using PBM could be an effective treatment modality for ARDS management in COVID-19 patients.

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