4.5 Article

Heterotopic Cesarean Scar Pregnancy An Analysis of 20 Cases Following in vitro Fertilization-Embryo Transfer

Journal

JOURNAL OF ULTRASOUND IN MEDICINE
Volume 40, Issue 10, Pages 2239-2249

Publisher

WILEY
DOI: 10.1002/jum.15610

Keywords

heterotopic cesarean scar pregnancy; in vitro fertilization-embryo transfer; first trimester; transvaginal sonography; expectant management; single embryo transfer

Funding

  1. Science and Technology Major Project of the Ministry of Science and Technology of Hunan Province, China [2017SK1030]
  2. China Postdoctoral Science Foundation [2019M652778]
  3. Science and Technology Project of Health and Family Planning Commission of Hunan Province [C20180289]
  4. Natural Science Foundation of Hunan Province [2020JJ5992]

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The study highlights the importance of accurate diagnosis using transvaginal sonography in the first trimester for patients with heterotopic cesarean scar pregnancy, particularly those with a history of in vitro fertilization-embryo transfer. It recommends single embryo transfer for such patients and suggests that expectant management may offer a chance for live cesarean scar pregnancy development, albeit with risks that need further verification in the future.
We report a series of 20 cases of heterotopic cesarean scar pregnancy in this study. The results show that transvaginal sonography offers highly accurate diagnoses of heterotopic cesarean scar pregnancy during the first trimester. Careful exclusion of cesarean scar pregnancy is of great clinical importance for patients with a history of cesarean section after in vitro fertilization-embryo transfer, even when an intrauterine pregnancy has been detected. We recommend single embryo transfer for patients with a history of cesarean section. Expectant management may provide the opportunity for a live cesarean scar pregnancy to develop, albeit at high risks of placenta accreta and hemorrhage, and this needs further verification in the future.

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