4.6 Article

Association of substance use disorders and drug overdose with adverse COVID-19 outcomes in New York City: January-October 2020

Journal

JOURNAL OF PUBLIC HEALTH
Volume 43, Issue 3, Pages 462-465

Publisher

OXFORD UNIV PRESS
DOI: 10.1093/pubmed/fdaa241

Keywords

COVID-19; substance use disorder; drug overdose

Funding

  1. New York University Center for Drug Use and HIV Research [P30 DA011041]
  2. New York University-City University of New York (NYU-CUNY) Prevention Research Center [U48 DP005008]
  3. New York State Department of Health Empire Clinical Research Investigator Program (ECRIP)

Ask authors/readers for more resources

The study indicates that patients with histories of substance use disorder (SUD) and drug overdose may face elevated risk of adverse COVID-19 outcomes.
Background Evidence suggests that individuals with history of substance use disorder (SUD) are at increased risk of COVID-19, but little is known about relationships between SUDs, overdose and COVID-19 severity and mortality. This study investigated risks of severe COVID-19 among patients with SUDs. Methods We conducted a retrospective review of data from a hospital system in New York City. Patient records from 1 January to 26 October 2020 were included. We assessed positive COVID-19 tests, hospitalizations, intensive care unit (ICU) admissions and death. Descriptive statistics and bivariable analyses compared the prevalence of COVID-19 by baseline characteristics. Logistic regression estimated unadjusted and sex-, age-, race- and comorbidity-adjusted odds ratios (AORs) for associations between SUD history, overdose history and outcomes. Results Of patients tested for COVID-19 (n = 188 653), 2.7% (n = 5107) had any history of SUD. Associations with hospitalization EAOR5 (95% confidence interval)] ranged from 1.78 (0.85-3.74) for cocaine use disorder (COUD) to 6.68 (4.33-10.33) for alcohol use disorder. Associations with ICU admission ranged from 0.57 (0.17-1.93) for COUD to 5.00 (3.02-8.30) for overdose. Associations with death ranged from 0.64 (0.14-2.84) for COUD to 3.03 (1.70-5.43) for overdose. Discussion Patients with histories of SUD and drug overdose may be at elevated risk of adverse COVID-19 outcomes.

Authors

I am an author on this paper
Click your name to claim this paper and add it to your profile.

Reviews

Primary Rating

4.6
Not enough ratings

Secondary Ratings

Novelty
-
Significance
-
Scientific rigor
-
Rate this paper

Recommended

No Data Available
No Data Available