4.7 Article

Unipept Desktop: A Faster, More Powerful Metaproteomics Results Analysis Tool

Journal

JOURNAL OF PROTEOME RESEARCH
Volume 20, Issue 4, Pages 2005-2009

Publisher

AMER CHEMICAL SOC
DOI: 10.1021/acs.jproteome.0c00855

Keywords

metaproteomics; proteogenomics; data analysis; interactive visualization; biodiversity analysis; functional analysis; comparative analysis

Funding

  1. Research Foundation. Flanders (FWO) [1164420N, 12I5220N, 1S90918N, G042518N]

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Metaproteomics has become an important research tool for studying microbial systems, leading to increased data generation. However, tools for processing this data have not kept pace. Unipept is a widely used tool for data interpretation, but its web-based implementation has limitations on data analysis. To address this, Unipept Desktop has been introduced to increase throughput and capacity for metaproteomics data analysis.
Metaproteomics has become an important research tool to study microbial systems, which has resulted in increased metaproteomics data generation. However, efficient tools for processing the acquired data have lagged behind. One widely used tool for metaproteomics data interpretation is Unipept, a web-based tool that provides, among others, interactive and insightful visualizations. Due to its web-based implementation, however, the Unipept web application is limited in the amount of data that can be analyzed. In this manuscript we therefore present Unipept Desktop, a desktop application version of Unipept that is designed to drastically increase the throughput and capacity of metaproteomics data analysis. Moreover, it provides a novel comparative analysis pipeline and improves the organization of experimental data into projects, thus addressing the growing need for more efficient and versatile analysis tools for metaproteomics data.

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