Journal
JOURNAL OF INFECTIOUS DISEASES
Volume 223, Issue -, Pages S194-S200Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/infdis/jiaa408
Keywords
bacteria; bile acids; Clostridioides difficile; microbiota; short-chain fatty acids
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Funding
- National Institute of General Medical Sciences of the National Institutes of Health [R35GM119438]
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Clostridioides difficile is an urgent antimicrobial-resistant bacterium causing a range of diseases, and commensal gut microbes play a critical role in providing resistance against it, potentially serving as a non-antibiotic alternative therapy for prevention and treatment.
Clostridioides difficile is an urgent antimicrobial-resistant bacterium, causing mild to moderate and sometimes life-threatening disease. Commensal gut microbes are critical for providing colonization resistance against C. difficile and can be leveraged as non-antibiotic alternative therapeutics for the prevention and treatment of C. difficile infection.
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