Journal
JOURNAL OF INFECTIOUS DISEASES
Volume 224, Issue 5, Pages 865-869Publisher
OXFORD UNIV PRESS INC
DOI: 10.1093/infdis/jiab024
Keywords
organ transplant; parvovirus B19, human; polymerase chain reaction; incidence
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Funding
- Novo Nordisk Foundation, Independent Research Fund (FSS)
- Danish National Research Foundation [DNRF126]
- Research Foundation of Rigshospitalet
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Routine monitoring of parvovirus B19 in seronegative solid organ transplant recipients may not be necessary, as targeted screening 1 month posttransplantation and screening upon clinical suspicion could be alternative strategies.
Routine monitoring of parvovirus B19 (B19V) the first 6 months posttransplantation was performed in 241 seronegative solid organ transplant (SOT) recipients. Incidence rates during the first month and the second to sixth months posttransplantation were 1.2 (95% confidence interval [CI], .33-3.2) and 0.21 (95% CI, .06-.57) per 100 recipients per month, respectively. Of the 6 SOT recipients with positive B19V polymerase chain reaction, 3 (50%) were admitted to hospital and 2 (33%) were treated with intravenous immunoglobulin. Thus, routine monitoring of B19V in seronegative SOT recipients may not be necessary. Targeted screening 1 month posttransplantation and screening upon clinical suspicion could be an alternative strategy.
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