Journal
JOURNAL OF HETEROCYCLIC CHEMISTRY
Volume 58, Issue 2, Pages 612-621Publisher
WILEY
DOI: 10.1002/jhet.4200
Keywords
-
Categories
Ask authors/readers for more resources
A new, efficient synthetic method has been developed for the synthesis of a novel series of derivatives containing 1,3,4-oxadiazole. The synthesized compounds showed significant biological responses in in vitro antidiabetic and antibacterial screening, indicating the potential of this method for drug discovery.
A modest, efficient, and mild synthetic procedure has been developed for the synthesis of novel series of 1,3,4-oxadiazole containing azaspirocycles derivatives. The reaction of 1,3,4-oxadiazole derivative with diverse azaspiro compounds under room temperature condition with helps of sodium iodide catalyst and polar aprotic solvent. Numerous compensations of this strategy embrace less time required, yield increment, consumption of all reactants, and mild condition. All synthesized compounds evaluated for in vitro antidiabetic and antibacterial screening. Among them some compounds show significant biological response.
Authors
I am an author on this paper
Click your name to claim this paper and add it to your profile.
Reviews
Recommended
No Data Available