One-pot synthesis of spiro-acridine/indoline and indoline derivatives using (MWCNTs)-COOH/La2O3 hybrid as an effective catalyst

Spiro-acridine/indoline and indoline derivatives were synthesized by the three-component reaction of isatin, dimedone, and amines or amino acids in the presence of acid-functionalized multiwalled carbon nanotubes/La2O3 (MWCNTs)-COOH/La2O3 hybrid (5 mol%) as a highly efficient catalyst in ethanol. The assigned structure was further established by CHN analysis, NMR, and FTIR spectra. (MWCNTs)-COOH/La2O3 was fabricated by the reaction of functionalized (MWCNTs)-COOH and La(NO3)(3).6H(2)O in acetic acid. Synthesis of La2O3 nanoparticles and their conjugation on the surface of MWCNT have been confirmed by FTIR, scanning electron microscopy, transmission electron microscopy, X-ray diffraction, and energy-dispersive X-ray spectroscopy.

Automated summary

Spiro-acridine/indoline and indoline derivatives were synthesized via the three-component reaction of isatin, dimedone, and amines or amino acids in the presence of acid-functionalized multiwalled carbon nanotubes/La2O3 hybrid as a highly efficient catalyst in ethanol. The structure was further confirmed by CHN analysis, NMR, and FTIR spectra. Fabrication of (MWCNTs)-COOH/La2O3 hybrid and confirmation of La2O3 nanoparticles conjugation on the MWCNT surface were achieved through various analytical techniques including FTIR, SEM, TEM, XRD, and EDX.