Related references
Note: Only part of the references are listed.MEG3 Induces Cervical Carcinoma Cells' Apoptosis Through Endoplasmic Reticulum Stress by miR-7-5p/STC1 Axis
Xi Pan et al.
CANCER BIOTHERAPY AND RADIOPHARMACEUTICALS (2021)
Emerging roles of long non-coding RNAs in breast cancer biology and management
I Amelio et al.
SEMINARS IN CANCER BIOLOGY (2021)
LncRNA MEG3 promotes endoplasmic reticulum stress and suppresses proliferation and invasion of colorectal carcinoma cells through the MEG3/miR-103a-3p/PDHB ceRNA pathway
Guoqin Wang et al.
NEOPLASMA (2021)
Xanthatin induces glioma cell apoptosis and inhibits tumor growth via activating endoplasmic reticulum stress-dependent CHOP pathway
Yu-yang Ma et al.
ACTA PHARMACOLOGICA SINICA (2020)
ASIP OUTSTANDING INVESTIGATOR AWARD LECTURE Endoplasmic Reticulum Stress Signaling in Cancer Cells
Scott A. Oakes
AMERICAN JOURNAL OF PATHOLOGY (2020)
撤稿声明: Downregulated long non-coding RNA FOXD3-AS1 promotes endoplasmic reticulum stress-induced apoptosis by inhibiting RCN1 via let-7e-5p in nasopharyngeal carcinoma (Retraction of 10.1152/AJPCELL.00352.2019, 2020)
Z. H. Huang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY (2020)
Exosomal transfer of miR-15b-3p enhances tumorigenesis and malignant transformation through the DYNLT1/Caspase-3/Caspase-9 signaling pathway in gastric cancer
Shuchun Wei et al.
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH (2020)
Circular RNA CRIM1 functions as a ceRNA to promote nasopharyngeal carcinoma metastasis and docetaxel chemoresistance through upregulating FOXQ1
Xiaohong Hong et al.
MOLECULAR CANCER (2020)
miR-7112-3p targets PERK to regulate the endoplasmic reticulum stress pathway and apoptosis induced by photodynamic therapy in colorectal cancer CX-1 cells
Fanhua Kong et al.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY (2020)
The lncRNA NORAD/miR-520a-3p Facilitates Malignancy in Non-Small Cell Lung Cancer via PI3k/Akt/mTOR Signaling Pathway
Yunyan Wan et al.
ONCOTARGETS AND THERAPY (2020)
Evaluating the Use of Circulating MicroRNA Profiles for Lung Cancer Detection in Symptomatic Patients
Tobias Fehlmann et al.
JAMA ONCOLOGY (2020)
microRNA: The Impact on Cancer Stemness and Therapeutic Resistance
Xueqiao Jiao et al.
CELLS (2020)
Spliced XBP1 Levels Determine Sensitivity of Multiple Myeloma Cells to Proteasome Inhibitor Bortezomib Independent of the Unfolded Protein Response Mediator GRP78
Bojana Borjan et al.
FRONTIERS IN ONCOLOGY (2020)
LncRNA NEAT1/miR-185-5p/IGF2 axis regulates the invasion and migration of colon cancer
Shu-tong Zhuang et al.
MOLECULAR GENETICS & GENOMIC MEDICINE (2020)
Clinicopathological significance of endoplasmic reticulum stress proteins in ovarian carcinoma
Soma Samanta et al.
SCIENTIFIC REPORTS (2020)
LncRNA LUCRC Regulates Colorectal Cancer Cell Growth and Tumorigenesis by Targeting Endoplasmic Reticulum Stress Response
Guo-Hui Tang et al.
FRONTIERS IN GENETICS (2020)
LncRNA OR3A4 Regulated the Growth of Osteosarcoma Cells by Modulating the miR-1207-5p/G6PD Signaling
Xiaole Wang et al.
ONCOTARGETS AND THERAPY (2020)
Long Noncoding RNA NEAT1 Upregulates Survivin and Facilitates Gallbladder Cancer Progression by Sponging microRNA-335
Facai Yang et al.
ONCOTARGETS AND THERAPY (2020)
Long Non-Coding RNA NEAT1 Serves as Sponge for miR-365a-3p to Promote Gastric Cancer Progression via Regulating ABCC4
Ming Gao et al.
ONCOTARGETS AND THERAPY (2020)
LncRNA GOLGA2P10 is induced by PERK/ATF4/CHOP signaling and protects tumor cells from ER stress-induced apoptosis by regulating Bcl-2 family members
Meng-Zhi Wu et al.
CELL DEATH & DISEASE (2020)
Long noncoding RNA AGPG regulates PFKFB3-mediated tumor glycolytic reprogramming
Jia Liu et al.
NATURE COMMUNICATIONS (2020)
Endoplasmic reticulum stress-induced exosomal miR-27a-3p promotes immune escape in breast cancer via regulating PD-L1 expression in macrophages
Xiaoli Yao et al.
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE (2020)
Roles of hsa-miR-12462 and SLC9A1 in acute myeloid leukemia
Yan Jia et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2020)
CircTLK1 promotes the proliferation and metastasis of renal cell carcinoma by sponging miR-136-5p
Jianfa Li et al.
MOLECULAR CANCER (2020)
被撤回的出版物: Circ_002117 binds to microRNA-370 and promotes endoplasmic reticulum stress-induced apoptosis in gastric cancer (Retracted article. See vol. 22, 2022)
Nan Zhou et al.
CANCER CELL INTERNATIONAL (2020)
Interactome analysis reveals that lncRNA HULC promotes aerobic glycolysis through LDHA and PKM2
Chunqing Wang et al.
NATURE COMMUNICATIONS (2020)
RNA Drugs and RNA Targets for Small Molecules: Principles, Progress, and Challenges
Ai-Ming Yu et al.
PHARMACOLOGICAL REVIEWS (2020)
Long non-coding RNA CASC2 enhances irradiation-induced endoplasmic reticulum stress in NSCLC cells through PERK signaling
Zhouli Ding et al.
3 BIOTECH (2020)
A Novel miRNA Restores the Chemosensitivity of AML Cells Through Targeting FosB
Huiwen Wang et al.
FRONTIERS IN MEDICINE (2020)
Transmissible ER stress reconfigures the AML bone marrow compartment
Ben Doron et al.
LEUKEMIA (2019)
High long non-coding RNA NORAD expression predicts poor prognosis and promotes breast cancer progression by regulating TGF- pathway
Ke Zhou et al.
CANCER CELL INTERNATIONAL (2019)
The Landscape of Circular RNA in Cancer
Josh N. Vo et al.
CELL (2019)
Role of Endoplasmic Reticulum Stress in the Anticancer Activity of Natural Compounds
Patrizia Limonta et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma
Shufang Jin et al.
MOLECULAR CANCER (2019)
MiR-451a suppressing BAP31 can inhibit proliferation and increase apoptosis through inducing ER stress in colorectal cancer
Ke Xu et al.
CELL DEATH & DISEASE (2019)
ER stress sensor, glucose regulatory protein 78 (GRP78) regulates redox status in pancreatic cancer thereby maintaining stemness
Patricia Dauer et al.
CELL DEATH & DISEASE (2019)
IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling
Xia Sheng et al.
NATURE COMMUNICATIONS (2019)
ER stress-induced mediator C/EBP homologous protein thwarts effector T cell activity in tumors through T-bet repression
Yu Cao et al.
NATURE COMMUNICATIONS (2019)
Overexpression of long non-coding RNA NORAD promotes invasion and migration in malignant melanoma via regulating the MIR-205-EGLN2 pathway
Yong Chen et al.
CANCER MEDICINE (2019)
MiR-657/ATF2 Signaling Pathway Has a Critical Role in Spatholobus suberectus Dunn Extract-Induced Apoptosis in U266 and U937 Cells
Hyun Ji Lim et al.
CANCERS (2019)
Pharmacological effectors of GRP78 chaperone in cancers
Christian Bailly et al.
BIOCHEMICAL PHARMACOLOGY (2019)
ZBTB7A, a miR-663a target gene, protects osteosarcoma from endoplasmic reticulum stress-induced apoptosis by suppressing LncRNA GAS5 expression
Lu Zhang et al.
CANCER LETTERS (2019)
Role of microRNAs, circRNAs and long noncoding RNAs in acute myeloid leukemia
Yan Liu et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
The IRE1 endoplasmic reticulum stress sensor activates natural killer cell immunity in part by regulating c-Myc
Han Dong et al.
NATURE IMMUNOLOGY (2019)
Noncoding RNAs in cancer therapy resistance and targeted drug development
Wen-Tao Wang et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2019)
Mutant p53 improves cancer cells' resistance to endoplasmic reticulum stress by sustaining activation of the UPR regulator ATF6
Dania Sicari et al.
ONCOGENE (2019)
Regulation of PERK expression by FOXO3: a vulnerability of drug-resistant cancer cells
Glowi Alasiri et al.
ONCOGENE (2019)
MiR-34c acts as a tumor suppressor in non-small cell lung cancer by inducing endoplasmic reticulum stress through targeting HMGB1
Li Tu et al.
ONCOTARGETS AND THERAPY (2019)
ATF6α Activation Enhances Survival against Chemotherapy and Serves as a Prognostic Indicator in Osteosarcoma
Suma Yarapureddy et al.
NEOPLASIA (2019)
Novel p97/VCP inhibitor induces endoplasmic reticulum stress and apoptosis in both bortezomib-sensitive and -resistant multiple myeloma cells
Nao Nishimura et al.
CANCER SCIENCE (2019)
Dual role of Endoplasmic Reticulum Stress-Mediated Unfolded Protein Response Signaling Pathway in Carcinogenesis
Natalia Siwecka et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
The Role of Non-coding RNAs in Oncology
Frank J. Slack et al.
CELL (2019)
LncRNA NEAT1 Promotes Proliferation, Migration And Invasion Via Regulating miR-296-5p/CNN2 Axis In Hepatocellular Carcinoma Cells
Yandong Li et al.
ONCOTARGETS AND THERAPY (2019)
CircCDR1as upregulates autophagy under hypoxia to promote tumor cell survival via AKT/ERK½/mTOR signaling pathways in oral squamous cell carcinomas
Ling Gao et al.
Cell Death & Disease (2019)
Long noncoding RNA MEG3 inhibits breast cancer growth via upregulating endoplasmic reticulum stress and activating NF-κB and p53
Yan Zhang et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
LincRNA-p21 enhances the sensitivity of radiotherapy for gastric cancer by targeting the β-catenin signaling pathway
Lijun Chen et al.
JOURNAL OF CELLULAR BIOCHEMISTRY (2019)
LINC02273 drives breast cancer metastasis by epigenetically increasing AGR2 transcription
Bingqiu Xiu et al.
MOLECULAR CANCER (2019)
Targeting Cancer Cell Dormancy
Ariadna Recasens et al.
TRENDS IN PHARMACOLOGICAL SCIENCES (2019)
PERK/eIF-2α/CHOP Pathway Dependent ROS Generation Mediates Butein-induced Non-small-cell Lung Cancer Apoptosis and G2/M Phase Arrest
Shouyin Di et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL SCIENCES (2019)
Molecular mechanisms for stemness maintenance of acute myeloid leukemia stem cells
Jiazhen Wang et al.
BLOOD SCIENCE (2019)
A PERK-miR-211 axis suppresses circadian regulators and protein synthesis to promote cancer cell survival
Yiwen Bu et al.
NATURE CELL BIOLOGY (2018)
The role of XBP1s in the metastasis and prognosis of hepatocellular carcinoma
Sudong Wu et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
miR-223/Hsp70/JNK/JUN/miR-223 feedback loop modulates the chemoresistance of osteosarcoma to cisplatin
Qi Tang et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
miRNA 146a promotes chemotherapy resistance in lung cancer cells by targeting DNA damage inducible transcript 3 (CHOP)
Wenfeng Tan et al.
CANCER LETTERS (2018)
Circular RNA: An emerging non-coding RNA as a regulator and biomarker in cancer
Bing Chen et al.
CANCER LETTERS (2018)
MiR-410 Acts as a Tumor Suppressor in Estrogen Receptor-Positive Breast Cancer Cells by Directly Targeting ERLIN2 via the ERS Pathway
Hewen Wu et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2018)
Activation of ER Stress-Dependent miR-216b Has a Critical Role in Salvia miltiorrhiza Ethanol-Extract-Induced Apoptosis in U266 and U937 Cells
Changmin Kim et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer
Na Zhao et al.
JOURNAL OF CLINICAL INVESTIGATION (2018)
Regulation of Cancer Stem Cell Self-Renewal by HOXB9 Antagonizes Endoplasmic Reticulum Stress-Induced Melanoma Cell Apoptosis via the miR-765-FOXA2 Axis
Jingrong Lin et al.
JOURNAL OF INVESTIGATIVE DERMATOLOGY (2018)
Overexpression of endoplasmic reticulum stress-related proteins, XBP1s and GRP78, predicts poor prognosis in pulmonary adenocarcinoma
Dohee Kwon et al.
LUNG CANCER (2018)
Resveratrol inhibits proliferation, migration and invasion of multiple myeloma cells via NEAT1-mediated Wnt/beta-catenin signaling pathway
Weizheng Geng et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
ER stress-related ATF6 upregulates CIP2A and contributes to poor prognosis of colon cancer
Chun-Yu Liu et al.
MOLECULAR ONCOLOGY (2018)
IRE1 alpha-XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity
Minkyung Song et al.
NATURE (2018)
miRNA-mediated TUSC3 deficiency enhances UPR and ERAD to promote metastatic potential of NSCLC
Young-Jun Jeon et al.
NATURE COMMUNICATIONS (2018)
A lifetime of stress: ATF6 in development and homeostasis
Robert F. Hillary et al.
JOURNAL OF BIOMEDICAL SCIENCE (2018)
ER Stress Signaling Promotes the Survival of Cancer Persister Cells Tolerant to EGFR Tyrosine Kinase Inhibitors
Hideki Terai et al.
CANCER RESEARCH (2018)
Non-coding RNAs as drug targets
Masayuki Matsui et al.
NATURE REVIEWS DRUG DISCOVERY (2017)
PERK inhibits DNA replication during the Unfolded Protein Response via Claspin and Chk1
E. Cabrera et al.
ONCOGENE (2017)
Noncoding RNAs and immune checkpoints-clinical implications as cancer therapeutics
Maria A. Smolle et al.
FEBS JOURNAL (2017)
Circular RNAs in cancer: an emerging key player
Yeping Dong et al.
JOURNAL OF HEMATOLOGY & ONCOLOGY (2017)
PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy
Iris C. Salaroglio et al.
MOLECULAR CANCER (2017)
Therapeutic implications of cellular and molecular biology of cancer stem cells in melanoma
Dhiraj Kumar et al.
MOLECULAR CANCER (2017)
Long non-coding RNA MEG3 induces cell apoptosis in esophageal cancer through endoplasmic reticulum stress
Zhen-Lun Huang et al.
ONCOLOGY REPORTS (2017)
Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells
Jeffrey J. Rodvold et al.
SCIENCE SIGNALING (2017)
MiR-1202 functions as a tumor suppressor in glioma cells by targeting Rab1A
Yu Quan et al.
TUMOR BIOLOGY (2017)
Melatonin, a novel selective ATF-6 inhibitor, induces human hepatoma cell apoptosis through COX-2 downregulation
Li-Jia Bu et al.
WORLD JOURNAL OF GASTROENTEROLOGY (2017)
Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1
Yu-Xiong Feng et al.
NATURE COMMUNICATIONS (2017)
miR-1271 inhibits ERα expression and confers letrozole resistance in breast cancer
Tao Yu et al.
ONCOTARGET (2017)
MicroRNA-128 suppresses paclitaxel-resistant lung cancer by inhibiting MUC1-C and BMI-1 in cancer stem cells
Hyebin Koh et al.
ONCOTARGET (2017)
MiR-410 induces stemness by inhibiting Gsk3β but upregulating β-catenin in non-small cells lung cancer
Xixian Ke et al.
ONCOTARGET (2017)
Common cytotoxic chemotherapeutics induce epithelial-mesenchymal transition (EMT) downstream of ER stress
Parag P. Shah et al.
ONCOTARGET (2017)
Intercellular transmission of the unfolded protein response promotes survival and drug resistance in cancer cells
Jeffrey J. Rodvold et al.
SCIENCE SIGNALING (2017)
Gemcitabine treatment induces endoplasmic reticular (ER) stress and subsequently upregulates urokinase plasminogen activator (uPA) to block mitochondrial-dependent apoptosis in Panc-1 cancer stem-like cells (CSCs)
Li Wang et al.
PLOS ONE (2017)
被撤回的出版物: Endoplasmic Reticulum Stress Promotes Autophagy and Apoptosis and Reduces Chemotherapy Resistance in Mutant p53 Lung Cancer Cells (Retracted article. See vol. 55, pg. 239, 2021)
Ping-Ping Gan et al.
CELLULAR PHYSIOLOGY AND BIOCHEMISTRY (2017)
Endoplasmic reticulum stress pathway PERK-eIF2 confers radioresistance in oropharyngeal carcinoma by activating NF-B
Qiao Qiao et al.
CANCER SCIENCE (2017)
A synthetic chalcone, 2′-hydroxy-2,3,5′-trimethoxychalcone triggers unfolded protein response-mediated apoptosis in breast cancer cells
Da Hyun Lee et al.
CANCER LETTERS (2016)
An Isogenic Human ESC Platform for Functional Evaluation of Genome-wide-Association-Study-Identified Diabetes Genes and Drug Discovery
Hui Zeng et al.
CELL STEM CELL (2016)
The Role of the PERK/eIF2 alpha/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress
W. Rozpedek et al.
CURRENT MOLECULAR MEDICINE (2016)
Endoplasmic reticulum stress induces 5-fluorouracil resistance in human colon cancer cells
Joon Ki Kim et al.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY (2016)
An initial phase of JNK activation inhibits cell death early in the endoplasmic reticulum stress response
Max Brown et al.
JOURNAL OF CELL SCIENCE (2016)
PERK Integrates Oncogenic Signaling and Cell Survival During Cancer Development
Yiwen Bu et al.
JOURNAL OF CELLULAR PHYSIOLOGY (2016)
Expression of GRP78, Master Regulator of the Unfolded Protein Response, Increases Chemoresistance in Pancreatic Ductal Adenocarcinoma
Jenifer B. Gifford et al.
MOLECULAR CANCER THERAPEUTICS (2016)
A network-biology perspective of microRNA function and dysfunction in cancer
Cameron P. Bracken et al.
NATURE REVIEWS GENETICS (2016)
Involvement of endoplasmic reticulum stress and p53 in lncRNA MEG3-induced human hepatoma HepG2 cell apoptosis
Rui-Pei Chen et al.
ONCOLOGY REPORTS (2016)
Hypoxic control of metastasis
Erinn B. Rankin et al.
SCIENCE (2016)
miR-663 overexpression induced by endoplasmic reticulum stress modulates hepatocellular carcinoma cell apoptosis via transforming growth factor beta 1
Yawei Huang et al.
ONCOTARGETS AND THERAPY (2016)
miR-216b regulation of c-Jun mediates GADD153/CHOP-dependent apoptosis
Zhenhua Xu et al.
NATURE COMMUNICATIONS (2016)
Role of SUMO activating enzyme in cancer stem cell maintenance and self-renewal
Li Du et al.
NATURE COMMUNICATIONS (2016)
An endoplasmic reticulum stress-regulated lncRNA hosting a microRNA megacluster induces early features of diabetic nephropathy
Mitsuo Kato et al.
NATURE COMMUNICATIONS (2016)
Inhibition of IRE1α-driven pro-survival pathways is a promising therapeutic application in acute myeloid leukemia
Haibo Sun et al.
ONCOTARGET (2016)
STAT3 and STAT6 Signaling Pathways Synergize to Promote Cathepsin Secretion from Macrophages via IRE1α Activation
Dongyao Yan et al.
CELL REPORTS (2016)
Overexpression of X-Box Binding Protein 1 (XBP1) Correlates to Poor Prognosis and Up-Regulation of PI3K/mTOR in Human Osteosarcoma
Jielai Yang et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2015)
Cell intrinsic and extrinsic activators of the unfolded protein response in cancer: Mechanisms and targets for therapy
Feven Tameire et al.
SEMINARS IN CANCER BIOLOGY (2015)
miR-15b-5p induces endoplasmic reticulum stress and apoptosis in human hepatocellular carcinoma, both in vitro and in vivo, by suppressing Rab1A
Yang Yang et al.
ONCOTARGET (2015)
LincRNA-p21 activates endoplasmic reticulum stress and inhibits hepatocellular carcinoma
Yang Ning et al.
ONCOTARGET (2015)
A novel chemical, STF-083010, reverses tamoxifen-related drug resistance in breast cancer by inhibiting IRE1/XBP1
Jie Ming et al.
ONCOTARGET (2015)
PERK silence inhibits glioma cell growth under low glucose stress by blockage of p-AKT and subsequent HK2′s mitochondria translocation
Xu Hou et al.
SCIENTIFIC REPORTS (2015)
The Malat1 long non-coding RNA is upregulated by signalling through the PERK axis of unfolded protein response during flavivirus infection
Sankar Bhattacharyya et al.
SCIENTIFIC REPORTS (2015)
GRP78 Protein Expression as Prognostic Values in Neoadjuvant Chemoradiotherapy and Laparoscopic Surgery for Locally Advanced Rectal Cancer
Hee Yeon Lee et al.
CANCER RESEARCH AND TREATMENT (2015)
Endoplasmic reticulum stress associated responses in cancer
Wen-An Wang et al.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH (2014)
Endoplasmic Reticulum Stress in Malignancy
Hanna J. Clarke et al.
CANCER CELL (2014)
High XBP1 expression is a marker of better outcome in multiple myeloma patients treated with bortezomib
Manuela Gambella et al.
HAEMATOLOGICA (2014)
ER stress regulates myeloid-derived suppressor cell fate through TRAIL-R-mediated apoptosis
Thomas Condamine et al.
JOURNAL OF CLINICAL INVESTIGATION (2014)
Endoplasmic Reticulum Stress-Activated Transcription Factor ATF6α Requires the Disulfide Isomerase PDIA5 To Modulate Chemoresistance
Arisa Higa et al.
MOLECULAR AND CELLULAR BIOLOGY (2014)
XBP1 promotes triple-negative breast cancer by controlling the HIF1α pathway
Xi Chen et al.
NATURE (2014)
Activating Transcription Factor 4 Promotes Esophageal Squamous Cell Carcinoma Invasion and Metastasis in Mice and Is Associated with Poor Prognosis in Human Patients
Hongwu Zhu et al.
PLOS ONE (2014)
Epithelial-to-Mesenchymal Transition Activates PERK-eIF2α and Sensitizes Cells to Endoplasmic Reticulum Stress
Yu-xiong Feng et al.
CANCER DISCOVERY (2014)
The impact of the endoplasmic reticulum protein-folding environment on cancer development
Miao Wang et al.
NATURE REVIEWS CANCER (2014)
Cell-extrinsic effects of the tumor unfolded protein response on myeloid cells and T cells
Maurizio Zanetti
RENAISSANCE OF CANCER IMMUNOTHERAPY (2013)
Hypoxic Activation of the PERK/eIF2α Arm of the Unfolded Protein Response Promotes Metastasis through Induction of LAMP3
Hilda Mujcic et al.
CLINICAL CANCER RESEARCH (2013)
Circular RNAs are a large class of animal RNAs with regulatory potency
Sebastian Memczak et al.
NATURE (2013)
miR-30d, miR-181a and miR-199a-5p cooperatively suppress the endoplasmic reticulum chaperone and signaling regulator GRP78 in cancer
S-F Su et al.
ONCOGENE (2013)
MicroRNA-1291-mediated silencing of IRE1α enhances Glypican-3 expression
Marion Maurel et al.
RNA (2013)
IRE1: ER stress sensor and cell fate executor
Yani Chen et al.
TRENDS IN CELL BIOLOGY (2013)
Discovery of GSK2656157: An Optimized PERK Inhibitor Selected for Preclinical Development
Jeffrey M. Axten et al.
ACS MEDICINAL CHEMISTRY LETTERS (2013)
Genome Regulation by Long Noncoding RNAs
John L. Rinn et al.
ANNUAL REVIEW OF BIOCHEMISTRY, VOL 81 (2012)
Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma
Naoya Mimura et al.
BLOOD (2012)
MicroRNA-30c-2*limits expression of proadaptive factor XBP1 in the unfolded protein response
Andrew E. Byrd et al.
JOURNAL OF CELL BIOLOGY (2012)
Discovery of 7-Methyl-5-(1-{[3-(trifluoromethyl)phenyl]acetyl}-2,3-dihydro-1H-indol-5-yl)-7H-pyrrolo[2,3-d]pyrimidin-4-amine (GSK2606414), a Potent and Selective First-in-Class Inhibitor of Protein Kinase R (PKR)-like Endoplasmic Reticulum Kinase (PERK)
Jeffrey M. Axten et al.
JOURNAL OF MEDICINAL CHEMISTRY (2012)
miR-211 Is a Prosurvival MicroRNA that Regulates chop Expression in a PERK-Dependent Manner
Nilesh S. Chitnis et al.
MOLECULAR CELL (2012)
Landscape of transcription in human cells
Sarah Djebali et al.
NATURE (2012)
An integrated encyclopedia of DNA elements in the human genome
Ian Dunham et al.
NATURE (2012)
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
Claudio Hetz
NATURE REVIEWS MOLECULAR CELL BIOLOGY (2012)
ER Stress Negatively Modulates the Expression of the miR-199a/214 Cluster to Regulates Tumor Survival and Progression in Human Hepatocellular Cancer
Quanlu Duan et al.
PLOS ONE (2012)
IRE1α Cleaves Select microRNAs During ER Stress to Derepress Translation of Proapoptotic Caspase-2
John-Paul Upton et al.
SCIENCE (2012)
Protein Folding and Quality Control in the ER
K. Araki et al.
Cold Spring Harbor Perspectives in Biology (2012)
Targeting autophagy enhances sorafenib lethality for hepatocellular carcinoma via ER stress-related apoptosis
Ying-Hong Shi et al.
AUTOPHAGY (2011)
Identification of an Ire1alpha endonuclease specific inhibitor with cytotoxic activity against human multiple myeloma
Ioanna Papandreou et al.
BLOOD (2011)
The Unfolded Protein Response (UPR)-activated Transcription Factor X-box-binding Protein 1 (XBP1) Induces MicroRNA-346 Expression That Targets the Human Antigen Peptide Transporter 1 (TAP1) mRNA and Governs Immune Regulatory Genes
Rafal Bartoszewski et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Akt is the downstream target of GRP78 in mediating cisplatin resistance in ER stress-tolerant human lung cancer cells
Yidan Lin et al.
LUNG CANCER (2011)
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
Ira Tabas et al.
NATURE CELL BIOLOGY (2011)
Transmission of endoplasmic reticulum stress and pro-inflammation from tumor cells to myeloid cells
Navin R. Mahadevan et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
Modulation of the Unfolded Protein Response Is the Core of MicroRNA-122-Involved Sensitivity to Chemotherapy in Hepatocellular Carcinoma
Fu Yang et al.
NEOPLASIA (2011)
miR-221/222 suppression protects against endoplasmic reticulum stress-induced apoptosis via p27Kip1- and MEK/ERK-mediated cell cycle regulation
Rongyang Dai et al.
BIOLOGICAL CHEMISTRY (2010)
XBP1s levels are implicated in the biology and outcome of myeloma mediating different clinical outcomes to thalidomide-based treatments
Tina Bagratuni et al.
BLOOD (2010)
MiR-199a-3p Regulates mTOR and c-Met to Influence the Doxorubicin Sensitivity of Human Hepatocarcinoma Cells
Francesca Fornari et al.
CANCER RESEARCH (2010)
The unfolded protein response protects human tumor cells during hypoxia through regulation of the autophagy genes MAP1LC3B and ATG5
Kasper M. A. Rouschop et al.
JOURNAL OF CLINICAL INVESTIGATION (2010)
Glucose-regulated protein 78 antagonizes cisplatin and adriamycin in human melanoma cells
Chen Chen Jiang et al.
CARCINOGENESIS (2009)
Mechanism of Drug Sensitivity and Resistance in Melanoma
Caterina A. M. La Porta
CURRENT CANCER DRUG TARGETS (2009)
Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development
Heather P. Harding et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2009)
Hypoxic activation of the unfolded protein response (UPR) induces expression of the metastasis-associated gene LAMP3
Hilda Mujcic et al.
RADIOTHERAPY AND ONCOLOGY (2009)
JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis
Vasileia-Ismini Alexaki et al.
PIGMENT CELL & MELANOMA RESEARCH (2008)
ATF6α-Rheb-mTOR signaling promotes survival of dormant tumor cells in vivo
Denis M. Schewe et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Integrated endoplasmic reticulum stress responses in cancer
Michel Moenner et al.
CANCER RESEARCH (2007)
Models, mechanisms and clinical evidence for cancer dormancy
Julio A. Aguirre-Ghiso
NATURE REVIEWS CANCER (2007)
Effects of the isoform-specific characteristics of ATF6α and ATF6β on endoplasmic reticulum stress response gene expression and cell viability
Donna J. Thuerauf et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2007)
Decay of endoplasmic reticulum-localized mRNAs during the unfolded protein response
Julie Hollien et al.
SCIENCE (2006)
Functional coupling of p38-induced up-regulation of BiP and activation of RNA-dependent protein kinase-like endoplasmic reticulum kinase to drug resistance of dormant carcinoma cells
AC Ranganathan et al.
CANCER RESEARCH (2006)
GCN2 phosphorylation of eIF2α activates NF-κB in response to UV irradiation
HY Jiang et al.
BIOCHEMICAL JOURNAL (2005)
XBP1 is essential for survival under hypoxic conditions and is required for tumor growth
L Romero-Ramirez et al.
CANCER RESEARCH (2004)
Nrf2 is a direct PERK substrate and effector of PERK-dependent cell survival
SB Cullinan et al.
MOLECULAR AND CELLULAR BIOLOGY (2003)
JNK phosphorylation of Bim-related members of the Bcl2 family induces Bax-dependent apoptosis
K Lei et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2003)
ER stress regulation of ATF6 localization by dissociation of BiP/GRP78 binding and unmasking of golgi localization signals
JS Shen et al.
DEVELOPMENTAL CELL (2002)
ASK1 is essential for endoplasmic reticulum stress-induced neuronal cell death triggered by expanded polyglutamine repeats
H Nishitoh et al.
GENES & DEVELOPMENT (2002)
PERK mediates cell-cycle exit during the mammalian unfolded protein response
JW Brewer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
A Bertolotti et al.
NATURE CELL BIOLOGY (2000)
Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
F Urano et al.
SCIENCE (2000)
Share Paper
