4.5 Article

Treatment of pediatric periorificial dermatitis with topical calcineurin inhibitor and topical/oral metronidazole

Journal

JOURNAL OF DERMATOLOGY
Volume 48, Issue 3, Pages 405-407

Publisher

WILEY
DOI: 10.1111/1346-8138.15695

Keywords

metronidazole; pediatric dermatology; pediatric periorificial dermatitis; perioral dermatitis; topical calcineurin inhibitor

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Pediatric periorificial dermatitis is a papulopustular eruption around the facial orifices in children, and treatment with topical calcineurin inhibitors and metronidazole can be effective. Studies have shown that most Korean patients have a good response to this treatment approach.
Pediatric periorificial dermatitis is a papulopustular eruption found around the facial orifices in children. Although the treatment of the disease has been largely anecdotal and experience-based, studies have shown that topical calcineurin inhibitors, as well as other topical and oral antibiotics, such as metronidazole, can be effective treatment options. However, most of the studies with a sizable number of patients have been based on the Caucasian population. Herein, we evaluated the clinical efficacy of topical calcineurin inhibitors and topical/oral metronidazole in 24 Korean patients with pediatric periorificial dermatitis. The majority of the patients showed a complete response to treatment.

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