4.3 Article

Malaria surveillance in the Democratic Republic of the Congo: comparison of microscopy, PCR, and rapid diagnostic test

Journal

DIAGNOSTIC MICROBIOLOGY AND INFECTIOUS DISEASE
Volume 85, Issue 1, Pages 16-18

Publisher

ELSEVIER SCIENCE INC
DOI: 10.1016/j.diagmicrobio.2016.01.004

Keywords

Malaria; Surveillance; Diagnostics; Microscopy; PCR; Rapid diagnostic test; RDT; Latent class analysis

Funding

  1. National Institutes of Health [5R01AI107949]
  2. National Science Foundation [BSC-1339949]
  3. Division Of Behavioral and Cognitive Sci
  4. Direct For Social, Behav & Economic Scie [1339949] Funding Source: National Science Foundation

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Malaria surveillance is critical for control efforts, but diagnostic methods frequently disagree. Here, we compare microscopy, PCR, and a rapid diagnostic test in 7137 samples from children in the Democratic Republic of the Congo using latent class analysis. PCR had the highest sensitivity (94.6%) and microscopy had the lowest (76.7%). (C) 2016 Elsevier Inc. All rights reserved.

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