Sustained Breast Development and Breast Anthropometric Changes in 3 Years of Gender-Affirming Hormone Treatment

Context Breast development is important for most trans women. An important limitation of current breast development measurement methods is that these do not allow for 3D volume analyses. Objectives To examine breast development and change in anthropometry during the first 3 years of gender-affirming hormone treatment using 3D imaging. Associations with clinical or laboratory parameters and satisfaction with the gained breast development were also studied. Design Prospective cohort study. Setting Specialized tertiary gender identity clinic in Amsterdam, the Netherlands. Participants Participants were 69 adult trans women with a median age of 26 years (interquartile range, 21-38). Interventions Gender-affirming hormone treatment. Main Outcome Measures Volumetric and anthropometric breast development and satisfaction. Results Breast volume increased by 72 cc (95% confidence interval [CI], 48-97) to 100 cc (standard deviation 48). This resulted in a cup-size

Automated summary

This study examined breast development in 69 adult trans women during the first 3 years of gender-affirming hormone treatment using 3D imaging, finding an average increase in breast volume of 72cc to 100cc, with high satisfaction with the breast development.