☆ 4.7 Article

In silico screening predicts common cold drug Dextromethorphan along with Prednisolone and Dexamethasone can be effective against novel Coronavirus disease (COVID-19)

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2022)

Related references

Note: Only part of the references are listed.

Article Biochemistry & Molecular Biology

Anisotine and amarogentin as promising inhibitory candidates against SARS-CoV-2 proteins: a computational investigation

Pallab Kar et al.

Summary: This study employed an in silico molecular interaction-based approach to evaluate the inhibitory potential of phytochemicals from Indian plants against key SARS-CoV-2 proteins. Two compounds showed promising inhibitory effects. These findings provide potential for further exploration of these compounds.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2022)

Add to Collection

Article Biochemistry & Molecular Biology

Repurposing of chloroquine and some clinically approved antiviral drugs as effective therapeutics to prevent cellular entry and replication of coronavirus

Akinwunmi O. Adeoye et al.

Summary: The study demonstrated the potential inhibitory effects of drugs like lopinavir and remdesivir on coronavirus, suggesting their repurposing as valuable treatments for preventing cellular entry and replication of the virus.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Moroccan Medicinal plants as inhibitors against SARS-CoV-2 main protease: Computational investigations

I. Aanouz et al.

Summary: The new coronavirus, known as SARS-CoV-2, first appeared in Wuhan, China. Research is being done on natural herbal remedies, with three molecules showing potential as inhibitors against the coronavirus.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2021)

Add to Collection

Article Biochemistry & Molecular Biology

In silico study the inhibition of angiotensin converting enzyme 2 receptor of COVID-19 by Ammoides verticillata components harvested from Western Algeria

Imane Abdelli et al.

Summary: The study focuses on screening an alternative drug to block ACE2 activity as a receptor for SARS-CoV-2, with Isothymol from Ammoides verticillata showing the best docking scores. This study suggests that Isothymol and other natural compounds could be potential inhibitors for the ACE2 receptor of SARS-CoV-2.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2021)

Add to Collection

Letter Biochemistry & Molecular Biology

Computational studies of drug repurposing and synergism of lopinavir, oseltamivir and ritonavir binding with SARS-CoV-2 protease against COVID-19

Nisha Muralidharan et al.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Using integrated computational approaches to identify safe and rapid treatment for SARS-CoV-2

Khattab Al-Khafaji et al.

Summary: The study evaluated FDA approved drugs for their effectiveness in forming a covalent bond with SARS-CoV-2 main protease, with the aim of identifying potential therapeutics for the treatment of COVID-19. The results showed promising binding energies for certain drugs, suggesting their potential use in the treatment of SARS-CoV-2.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Design of multi-epitope vaccine candidate against SARS-CoV-2: ain-silicostudy

K. Abraham Peele et al.

Summary: A novel multi-epitope vaccine was designed using in silico tools, potentially triggering both CD4 and CD8 T-cell immune responses against the novel Coronavirus. The vaccine candidate utilized B and T-cell epitopes as immunogens, successfully eliciting immune response in the host system.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2021)

Add to Collection

Article Biochemistry & Molecular Biology

Homology modeling andin silicodesign of novel and potential dual-acting inhibitors of human histone deacetylases HDAC5 and HDAC9 isozymes

Ammar D. Elmezayen et al.

Summary: In this study, protein models of HDAC5 and HDAC9 were constructed using homology modeling approach based on a template. The selected models were validated and subjected to molecular dynamic simulations, which indicated their stability and reliability for designing novel inhibitors targeting HDAC5 and HDAC9. The results obtained in this study could be valuable for future drug design efforts against these enzymes.

JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS (2021)

Add to Collection

Article Cell Biology

COVID-19 and chronological aging: senolytics and other anti-aging drugs for the treatment or prevention of corona virus infection?

Camillo Sargiacomo et al.

AGING-US (2020)

Add to Collection

Review Immunology

COVID-19 infection and rheumatoid arthritis: Faraway, so close!

Ennio Giulio Favalli et al.

AUTOIMMUNITY REVIEWS (2020)

Add to Collection

Editorial Material Multidisciplinary Sciences

Rapid repurposing of drugs for COVID-19

R. Kiplin Guy et al.

SCIENCE (2020)

Add to Collection

Article Rheumatology

On the Alert for Cytokine Storm: Immunopathology in COVID-19

Lauren A. Henderson et al.

ARTHRITIS & RHEUMATOLOGY (2020)

Add to Collection

Review Infectious Diseases

COVID-19, SARS and MERS: are they closely related?

N. Petrosillo et al.

CLINICAL MICROBIOLOGY AND INFECTION (2020)

Add to Collection

Letter Public, Environmental & Occupational Health

Dexamethasone: A boon for critically ill COVID-19 patients?

Shailesh Kumar Patel et al.

TRAVEL MEDICINE AND INFECTIOUS DISEASE (2020)

Add to Collection

Article Chemistry, Multidisciplinary

Molecular determinants of vascular transport of dexamethasone in COVID-19 therapy

Ivan G. Shabalin et al.

IUCRJ (2020)

Add to Collection

Article Physics, Multidisciplinary

Consistent thermostatistics forbids negative absolute temperatures

Joern Dunkel et al.

NATURE PHYSICS (2014)

Add to Collection

Article Biochemical Research Methods

GROMACS 4.5: a high-throughput and highly parallel open source molecular simulation toolkit

Sander Pronk et al.

BIOINFORMATICS (2013)

Add to Collection

Article Pharmacology & Pharmacy

Antitussive activity of sigma-1 receptor agonists in the guinea-pig

C Brown et al.

BRITISH JOURNAL OF PHARMACOLOGY (2004)

Add to Collection

© Peeref 2019-2024. All rights reserved.