Related references
Note: Only part of the references are listed.Selective targeting of 3 repeat Tau with brain penetrating single chain antibodies for the treatment of neurodegenerative disorders
Brian Spencer et al.
ACTA NEUROPATHOLOGICA (2018)
The Neurotoxic Role of Extracellular Tau Protein
Alvaro Sebastian-Serrano et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)
Anti-tau conformational scFv MC1 antibody efficiently reduces pathological tau species in adult JNPL3 mice
Francesca Vitale et al.
ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)
AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy
Christina Ising et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2017)
Extracellular Tau and Its Potential Role in the Propagation of Tau Pathology
Kaoru Yamada
FRONTIERS IN NEUROSCIENCE (2017)
Chaperone-like Antibodies Targeting Misfolded Tau Protein: New Vistas in the Immunotherapy of Neurodegenerative Foldopathies
Norbert Zilka et al.
JOURNAL OF ALZHEIMERS DISEASE (2017)
Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory
M. Fa et al.
SCIENTIFIC REPORTS (2016)
Effects of Tau Domain-Specific Antibodies and Intravenous lmmunoglobulin on Tau Aggregation and Aggregate Degradation
Jose O. Esteves-Villanueva et al.
BIOCHEMISTRY (2015)
Further understanding of tau phosphorylation: implications for therapy
Miguel Medina et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2015)
Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation
Hilda Mirbaha et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2015)
Further understanding of tau phosphorylation: implications for therapy
Miguel Medina et al.
EXPERT REVIEW OF NEUROTHERAPEUTICS (2015)
Passive immunotherapy of tauopathy targeting pSer413-tau: a pilot study in mice
Tomohiro Umeda et al.
ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2015)
Tau-aggregation inhibitor therapy for Alzheimer's disease
Claude M. Wischik et al.
BIOCHEMICAL PHARMACOLOGY (2014)
Amplification of Tau Fibrils from Minute Quantities of Seeds
Virginia Meyer et al.
BIOCHEMISTRY (2014)
TOC1: Characterization of a Selective Oligomeric Tau Antibody
Sarah M. Ward et al.
JOURNAL OF ALZHEIMERS DISEASE (2013)
Anti-Tau Antibodies that Block Tau Aggregate Seeding In Vitro Markedly Decrease Pathology and Improve Cognition In Vivo
Kiran Yanamandra et al.
NEURON (2013)
Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity
Cristina d'Abramo et al.
PLOS ONE (2013)
Potential synergy between tau aggregation inhibitors and tau chaperone modulators
Laura J. Blair et al.
ALZHEIMERS RESEARCH & THERAPY (2013)
The Alzheimer's Disease Related Tau Protein as a New Target for Chemical Protein Engineering
Malgorzata Broncel et al.
CHEMISTRY-A EUROPEAN JOURNAL (2012)
scFv Antibody: Principles and Clinical Application
Zuhaida Asra Ahmad et al.
CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2012)
Immunotherapy for Alzheimer's disease: from anti-β-amyloid to tau-based immunization strategies
Francesco Panza et al.
IMMUNOTHERAPY (2012)
Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability
Katharina Flach et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2012)
Propagation of Tau Pathology in a Model of Early Alzheimer's Disease
Alix de Calignon et al.
NEURON (2012)
The Contrasting Effect of Macromolecular Crowding on Amyloid Fibril Formation
Qian Ma et al.
PLOS ONE (2012)
Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau
Cristian A. Lasagna-Reeves et al.
SCIENTIFIC REPORTS (2012)
Passive Immunization with Anti-Tau Antibodies in Two Transgenic Models REDUCTION OF TAU PATHOLOGY AND DELAY OF DISEASE PROGRESSION
Xiyun Chai et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2011)
Passive immunization targeting pathological phospho-tau protein in a mouse model reduces functional decline and clears tau aggregates from the brain
Allal Boutajangout et al.
JOURNAL OF NEUROCHEMISTRY (2011)
Aggregation of Detergent-insoluble Tau Is Involved in Neuronal Loss but Not in Synaptic Loss
Tetsuya Kimura et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2010)
Aβ-directed Single-chain Antibody Delivery Via a Serotype-1 AAV Vector Improves Learning Behavior and Pathology in Alzheimer's Disease Mice
Deborah A. Ryan et al.
MOLECULAR THERAPY (2010)
Radiosensitization and growth inhibition of cancer cells mediated by an scFv antibody gene against DNA-PKcs in vitro and in vivo
Li Du et al.
RADIATION ONCOLOGY (2010)
Crowded Cell-like Environment Accelerates the Nucleation Step of Amyloidogenic Protein Misfolding
Zheng Zhou et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2009)
Beyond the neurotransmitter-focused approach in treating Alzheimer's Disease: drugs targeting β-amyloid and tau protein
Francesco Panza et al.
AGING CLINICAL AND EXPERIMENTAL RESEARCH (2009)
An scFv intrabody against the nonamyloid component of α-synuclein reduces intracellular aggregation and toxicity
Sandra M. Lynch et al.
JOURNAL OF MOLECULAR BIOLOGY (2008)
The toxicity of β-amyloid is attenuated by interaction with its specific human scFv E3 in vitro
Shen Yue et al.
LIFE SCIENCES (2008)
Initiation and elongation in fibrillation of ALS-linked superoxide dismutase
Madhuri Chattopadhyay et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)
Phenylthiazolyl-hydrazide and its derivatives are potent inhibitors of τ aggregation and toxicity in vitro and in cells
Marcus Pickhardt et al.
BIOCHEMISTRY (2007)
How can biochemical reactions within cells differ from those in test tubes?
Allen P. Minton
JOURNAL OF CELL SCIENCE (2006)
Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins
S Taniguchi et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
Effects of different anti-tau antibodies on tau fibrillogenesis: RTA-1 and RTA-2 counteract tau aggregation
T Taniguchi et al.
FEBS LETTERS (2005)
Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells
M Pickhardt et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2005)
PAR-1 kinase plays an initiator role in a temporally ordered phosphorylation process that confers tau toxicity in Drosophila
I Nishimura et al.
CELL (2004)
Biochemical effects of molecular crowding
NA Chebotareva et al.
BIOCHEMISTRY-MOSCOW (2004)
Alzheimer's disease:: β-amyloid protein and tau
M Morishima-Kawashima et al.
JOURNAL OF NEUROSCIENCE RESEARCH (2002)
Heparin and other glycosaminoglycans stimulate the formation of amyloid fibrils from α-synuclein in vitro
JA Cohlberg et al.
BIOCHEMISTRY (2002)
Macromolecular crowding: an important but neglected aspect of the intracellular environment
RJ Ellis
CURRENT OPINION IN STRUCTURAL BIOLOGY (2001)