4.5 Article

A Single-Chain Variable Fragment Antibody Inhibits Aggregation of Phosphorylated Tau and Ameliorates Tau Toxicity in vitro and in vivo

Related references

Note: Only part of the references are listed.
Review Biochemistry & Molecular Biology

The Neurotoxic Role of Extracellular Tau Protein

Alvaro Sebastian-Serrano et al.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2018)

Article Neurosciences

Anti-tau conformational scFv MC1 antibody efficiently reduces pathological tau species in adult JNPL3 mice

Francesca Vitale et al.

ACTA NEUROPATHOLOGICA COMMUNICATIONS (2018)

Article Immunology

AAV-mediated expression of anti-tau scFvs decreases tau accumulation in a mouse model of tauopathy

Christina Ising et al.

JOURNAL OF EXPERIMENTAL MEDICINE (2017)

Review Neurosciences

Extracellular Tau and Its Potential Role in the Propagation of Tau Pathology

Kaoru Yamada

FRONTIERS IN NEUROSCIENCE (2017)

Article Multidisciplinary Sciences

Extracellular Tau Oligomers Produce An Immediate Impairment of LTP and Memory

M. Fa et al.

SCIENTIFIC REPORTS (2016)

Article Biochemistry & Molecular Biology

Effects of Tau Domain-Specific Antibodies and Intravenous lmmunoglobulin on Tau Aggregation and Aggregate Degradation

Jose O. Esteves-Villanueva et al.

BIOCHEMISTRY (2015)

Review Clinical Neurology

Further understanding of tau phosphorylation: implications for therapy

Miguel Medina et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2015)

Article Biochemistry & Molecular Biology

Tau Trimers Are the Minimal Propagation Unit Spontaneously Internalized to Seed Intracellular Aggregation

Hilda Mirbaha et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2015)

Review Clinical Neurology

Further understanding of tau phosphorylation: implications for therapy

Miguel Medina et al.

EXPERT REVIEW OF NEUROTHERAPEUTICS (2015)

Article Clinical Neurology

Passive immunotherapy of tauopathy targeting pSer413-tau: a pilot study in mice

Tomohiro Umeda et al.

ANNALS OF CLINICAL AND TRANSLATIONAL NEUROLOGY (2015)

Review Pharmacology & Pharmacy

Tau-aggregation inhibitor therapy for Alzheimer's disease

Claude M. Wischik et al.

BIOCHEMICAL PHARMACOLOGY (2014)

Article Biochemistry & Molecular Biology

Amplification of Tau Fibrils from Minute Quantities of Seeds

Virginia Meyer et al.

BIOCHEMISTRY (2014)

Article Neurosciences

TOC1: Characterization of a Selective Oligomeric Tau Antibody

Sarah M. Ward et al.

JOURNAL OF ALZHEIMERS DISEASE (2013)

Article Multidisciplinary Sciences

Tau Passive Immunotherapy in Mutant P301L Mice: Antibody Affinity versus Specificity

Cristina d'Abramo et al.

PLOS ONE (2013)

Review Clinical Neurology

Potential synergy between tau aggregation inhibitors and tau chaperone modulators

Laura J. Blair et al.

ALZHEIMERS RESEARCH & THERAPY (2013)

Article Chemistry, Multidisciplinary

The Alzheimer's Disease Related Tau Protein as a New Target for Chemical Protein Engineering

Malgorzata Broncel et al.

CHEMISTRY-A EUROPEAN JOURNAL (2012)

Review Immunology

scFv Antibody: Principles and Clinical Application

Zuhaida Asra Ahmad et al.

CLINICAL & DEVELOPMENTAL IMMUNOLOGY (2012)

Article Biochemistry & Molecular Biology

Tau Oligomers Impair Artificial Membrane Integrity and Cellular Viability

Katharina Flach et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2012)

Article Neurosciences

Propagation of Tau Pathology in a Model of Early Alzheimer's Disease

Alix de Calignon et al.

NEURON (2012)

Article Multidisciplinary Sciences

The Contrasting Effect of Macromolecular Crowding on Amyloid Fibril Formation

Qian Ma et al.

PLOS ONE (2012)

Article Multidisciplinary Sciences

Alzheimer brain-derived tau oligomers propagate pathology from endogenous tau

Cristian A. Lasagna-Reeves et al.

SCIENTIFIC REPORTS (2012)

Article Biochemistry & Molecular Biology

Aggregation of Detergent-insoluble Tau Is Involved in Neuronal Loss but Not in Synaptic Loss

Tetsuya Kimura et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2010)

Article Biochemistry & Molecular Biology

Crowded Cell-like Environment Accelerates the Nucleation Step of Amyloidogenic Protein Misfolding

Zheng Zhou et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2009)

Review Geriatrics & Gerontology

Beyond the neurotransmitter-focused approach in treating Alzheimer's Disease: drugs targeting β-amyloid and tau protein

Francesco Panza et al.

AGING CLINICAL AND EXPERIMENTAL RESEARCH (2009)

Article Biochemistry & Molecular Biology

An scFv intrabody against the nonamyloid component of α-synuclein reduces intracellular aggregation and toxicity

Sandra M. Lynch et al.

JOURNAL OF MOLECULAR BIOLOGY (2008)

Article Medicine, Research & Experimental

The toxicity of β-amyloid is attenuated by interaction with its specific human scFv E3 in vitro

Shen Yue et al.

LIFE SCIENCES (2008)

Article Multidisciplinary Sciences

Initiation and elongation in fibrillation of ALS-linked superoxide dismutase

Madhuri Chattopadhyay et al.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2008)

Article Cell Biology

How can biochemical reactions within cells differ from those in test tubes?

Allen P. Minton

JOURNAL OF CELL SCIENCE (2006)

Article Biochemistry & Molecular Biology

Inhibition of heparin-induced tau filament formation by phenothiazines, polyphenols, and porphyrins

S Taniguchi et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Article Biochemistry & Molecular Biology

Anthraquinones inhibit tau aggregation and dissolve Alzheimer's paired helical filaments in vitro and in cells

M Pickhardt et al.

JOURNAL OF BIOLOGICAL CHEMISTRY (2005)

Review Biochemistry & Molecular Biology

Biochemical effects of molecular crowding

NA Chebotareva et al.

BIOCHEMISTRY-MOSCOW (2004)

Review Neurosciences

Alzheimer's disease:: β-amyloid protein and tau

M Morishima-Kawashima et al.

JOURNAL OF NEUROSCIENCE RESEARCH (2002)

Article Biochemistry & Molecular Biology

Macromolecular crowding: an important but neglected aspect of the intracellular environment

RJ Ellis

CURRENT OPINION IN STRUCTURAL BIOLOGY (2001)