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CHEMMEDCHEM (2007)
Chemistry and biology of resorcylic acid lactones
Nicolas Winssinger et al.
CHEMICAL COMMUNICATIONS (2007)
Modular synthesis of radicicol a and related resorcylic acid lactones, potent kinase inhibitors
Pierre-Yves Dakas et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2007)
Inhibitory effect of Andrographis paniculata extract and its active diterpenoids on platelet aggregation
Piengpen Thisoda et al.
EUROPEAN JOURNAL OF PHARMACOLOGY (2006)
Isodeoxyelephantopin, a novel sesquiterpene lactone, potentiates apoptosis, inhibits invasion, and abolishes osteoclastogenesis through suppression of nuclear factor-κB (NF-κB) activation and NF-κB-regulated gene expression
Haruyo Ichikawa et al.
CLINICAL CANCER RESEARCH (2006)
Synthesis of 13-amino costunolide derivatives as anticancer agents
Sanjay K. Srivastava et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2006)
Targeted covalent inactivation of protein kinases by resorcylic acid lactone polyketides
A Schirmer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2006)
Inhibtion of VEGFR-3 activation with the antagonistic antibody more potently suppresses lymph node and distant metastases than inactivation of VEGFR-2
N Roberts et al.
CANCER RESEARCH (2006)
Biosynthesis of plant volatiles: Nature's diversity and ingenuity
E Pichersky et al.
SCIENCE (2006)
Total synthesis of (-)-scabronine G, an inducer of neurotrophic factor production
SP Waters et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2005)
Solution- and solid-phase synthesis of radicicol (monorden) and pochonin C
S Barluenga et al.
CHEMISTRY-A EUROPEAN JOURNAL (2005)
Therapeutic roles of peroxisome proliferator-activated receptor agonists
B Staels et al.
DIABETES (2005)
The sesquiterpene lactone parthenolide in combination with docetaxel reduces metastasis and improves survival in a xenograft model of breast cancer
CJ Sweeney et al.
MOLECULAR CANCER THERAPEUTICS (2005)
Metathesis reactions in total synthesis
KC Nicolaou et al.
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION (2005)
Involvement of proapoptotic Bcl-2 family members in parthenolide-induced mitochondrial dysfunction and apoptosis
SY Zhang et al.
CANCER LETTERS (2004)
Phase I dose escalation trial of feverfew with standardized doses of parthenolide in patients with cancer
EA Curry et al.
INVESTIGATIONAL NEW DRUGS (2004)
Macrocyclic diacylglycerol-bis-lactones as conformationally constrained analogues of diacylglycerol-lactones. Interactions with protein kinase C
JH Kang et al.
JOURNAL OF MEDICINAL CHEMISTRY (2004)
Crosstalk between angiogenesis and lymphangiogenesis in tumor progression
C Scavelli et al.
LEUKEMIA (2004)
A novel synthesis of functionalized allylsilanes
WDZ Li et al.
ORGANIC LETTERS (2004)
Terpenoid metabolism in wild-type and transgenic Arabidopsis plants
A Aharoni et al.
PLANT CELL (2003)
Synthesis of (-)-nakamurol A and assignment of absolute configuration of diterpenoid (+)-nakamurol A
S Díaz et al.
JOURNAL OF ORGANIC CHEMISTRY (2003)
A concise route to benzofused macrolactones via ynolides: Cycloproparadicicol
ZQ Yang et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2003)
Synthetic diacylglycerols (DAG) and DAG-lactones as activators of protein kinase C (PK-C)
VE Marquez et al.
ACCOUNTS OF CHEMICAL RESEARCH (2003)
A resorcylic acid lactone, 5Z-7-oxozeaenol, prevents inflammation by inhibiting the catalytic activity of TAK1 MAPK kinase kinase
J Ninomiya-Tsuji et al.
JOURNAL OF BIOLOGICAL CHEMISTRY (2003)
Antibacterial evaluation of cnicin and some natural and semisynthetic analogues
M Bruno et al.
PLANTA MEDICA (2003)
Costunolide, a sesquiterpene lactone from Saussurea lappa, inhibits the VEGFR KDR/Flk-1 signaling pathway
SJ Jeong et al.
CANCER LETTERS (2002)
Halohydrin and oxime derivatives of radicicol: Synthesis and antitumor activities
T Agatsuma et al.
BIOORGANIC & MEDICINAL CHEMISTRY (2002)
Convergent stereospecific synthesis of C292 (or LL-Z1640-2), and hypothemycin.: Part 1
P Sellès et al.
TETRAHEDRON LETTERS (2002)
Balancing the activation state of the endothelium via two distinct TGF-β type I receptors
MJ Goumans et al.
EMBO JOURNAL (2002)
Enantioselective synthesis of the antiinflammatory agent (-)-acanthoic acid
TT Ling et al.
JOURNAL OF ORGANIC CHEMISTRY (2001)
Concise asymmetric syntheses of radicicol and monocillin I
RM Garbaccio et al.
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY (2001)
The anti-inflammatory natural product parthenolide from the medicinal herb Feverfew directly binds to and inhibits IκB kinase
BHB Kwok et al.
CHEMISTRY & BIOLOGY (2001)
Cytotoxic Michael-type amine adducts of α-methylene lactones alantolactone and isoalantolactone
NJ Lawrence et al.
BIOORGANIC & MEDICINAL CHEMISTRY LETTERS (2001)
The first total synthesis of a macrocyclic anti-protozoan, LL-Z1640-2
K Tatsuta et al.
CHEMISTRY LETTERS (2001)
Efficient asymmetric synthesis of radicicol dimethyl ether: A novel application of ring-forming olefin metathesis
RM Garbaccio et al.
ORGANIC LETTERS (2000)
Absolute stereostructures and syntheses of saussureamines A, B, C, D and E, amino acid-sesquiterpene conjugates with gastroprotective effect, from the roots of Saussurea lappa
H Matsuda et al.
TETRAHEDRON (2000)
The role of the redox protein thioredoxin in cell growth and cancer
G Powis et al.
FREE RADICAL BIOLOGY AND MEDICINE (2000)