Related references
Note: Only part of the references are listed.Human Glioma Cells Acquire Temozolomide Resistance After Repeated Drug Exposure Via DNA Mismatch Repair Dysfunction
Kei Yamashiro et al.
ANTICANCER RESEARCH (2020)
Infiltration of CD163-positive macrophages in glioma tissues after treatment with anti-PD-L1 antibody and role of PI3Kγ inhibitor as a combination therapy with anti-PD-L1 antibody in in vivo model using temozolomide-resistant murine glioma-initiating cells
Tsubasa Miyazaki et al.
BRAIN TUMOR PATHOLOGY (2020)
A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity
Fadi Jacob et al.
CELL (2020)
Smoothened Promotes Glioblastoma Radiation Resistance Via Activating USP3-Mediated Claspin Deubiquitination
Yiming Tu et al.
CLINICAL CANCER RESEARCH (2020)
Replication Protein A (RPA) Mediates Radio-Resistance of Glioblastoma Cancer Stem-Like Cells
Henriette Pedersen et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2020)
DNA-methylation-mediated activating of lncRNA SNHG12 promotes temozolomide resistance in glioblastoma
Chenfei Lu et al.
MOLECULAR CANCER (2020)
Fyn tyrosine kinase, a downstream target of receptor tyrosine kinases, modulates antiglioma immune responses
Andrea Comba et al.
NEURO-ONCOLOGY (2020)
Wnt-mediated endothelial transformation into mesenchymal stem cell-like cells induces chemoresistance in glioblastoma
Menggui Huang et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
PDZ-Binding kinase-Dependent Transcriptional Regulation of CCNB2 Promotes Tumorigenesis and Radio-Resistance in Glioblastoma
Ping Mao et al.
TRANSLATIONAL ONCOLOGY (2020)
Intratumoral Heterogeneity and Longitudinal Changes in Gene Expression Predict Differential Drug Sensitivity in Newly Diagnosed and Recurrent Glioblastoma
Ella L. Kim et al.
CANCERS (2020)
Impact of Radiochemotherapy on Immune Cell Subtypes in High-Grade Glioma Patients
Valerie Dutoit et al.
FRONTIERS IN ONCOLOGY (2020)
Identification of a combination of transcription factors that synergistically increases endothelial cell barrier resistance
Filip Roudnicky et al.
SCIENTIFIC REPORTS (2020)
Single-Cell Mapping of Human Brain Cancer Reveals Tumor-Specific Instruction of Tissue-Invading Leukocytes
Ekaterina Friebel et al.
CELL (2020)
Interrogation of the Microenvironmental Landscape in Brain Tumors Reveals Disease-Specific Alterations of Immune Cells
Florian Klemm et al.
CELL (2020)
Surface modified silk fibroin nanoparticles for improved delivery of doxorubicin: Development, characterization, in-vitro studies
Vikas Pandey et al.
INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES (2020)
Ivosidenib in Isocitrate Dehydrogenase 1-Mutated Advanced Glioma
Ingo K. Mellinghoff et al.
JOURNAL OF CLINICAL ONCOLOGY (2020)
Neuronavigation-guided focused ultrasound (NaviFUS) for transcranial blood-brain barrier opening in recurrent glioblastoma patients: clinical trial protocol
Ko-Ting Chen et al.
ANNALS OF TRANSLATIONAL MEDICINE (2020)
Dynamic changes in glioma macrophage populations after radiotherapy reveal CSF-1R inhibition as a strategy to overcome resistance
Leila Akkari et al.
SCIENCE TRANSLATIONAL MEDICINE (2020)
Immunotherapy in CNS cancers: the role of immune cell trafficking
Nivedita M. Ratnam et al.
NEURO-ONCOLOGY (2019)
Evolutionary Trajectories of IDHWT Glioblastomas Reveal a Common Path of Early Tumorigenesis Instigated Years ahead of Initial Diagnosis
Verena Koerber et al.
CANCER CELL (2019)
Ly6G+ inflammatory cells enable the conversion of cancer cells to cancer stem cells in an irradiated glioblastoma model
Hee-Young Jeon et al.
CELL DEATH AND DIFFERENTIATION (2019)
Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors
Niklas Schaefer et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2019)
Neoadjuvant nivolumab modifies the tumor immune microenvironment in resectable glioblastoma
Kurt A. Schalper et al.
NATURE MEDICINE (2019)
Immune and genomic correlates of response to anti-PD-1 immunotherapy in glioblastoma
Junfei Zhao et al.
NATURE MEDICINE (2019)
The Genetic Landscape of Human Glioblastoma and Matched Primary Cancer Stem Cells Reveals Intratumour Similarity and Intertumour Heterogeneity
Chiara Pesenti et al.
STEM CELLS INTERNATIONAL (2019)
Intratumoural Heterogeneity Underlies Distinct Therapy Responses and Treatment Resistance in Glioblastoma
Seckin Akgul et al.
CANCERS (2019)
Combination anti-CXCR4 and anti-PD-1 immunotherapy provides survival benefit in glioblastoma through immune cell modulation of tumor microenvironment
Adela Wu et al.
JOURNAL OF NEURO-ONCOLOGY (2019)
Intertumoral heterogeneity in patient-specific drug sensitivities in treatment-naive glioblastoma
Erlend Skaga et al.
BMC CANCER (2019)
An Integrative Model of Cellular States, Plasticity, and Genetics for Glioblastoma
Cyril Neftel et al.
CELL (2019)
A Phase 0 Trial of Ribociclib in Recurrent Glioblastoma Patients Incorporating a Tumor Pharmacodynamic- and Pharmacokinetic-Guided Expansion Cohort
An-Chi Tien et al.
CLINICAL CANCER RESEARCH (2019)
GARP as an Immune Regulatory Molecule in the Tumor Microenvironment of Glioblastoma Multiforme
Niklas Zimmer et al.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES (2019)
Genome-Wide CRISPR-Cas9 Screening Identifies NF-κB/E2F6 Responsible for EGFRvIII-Associated Temozolomide Resistance in Glioblastoma
Kai Huang et al.
ADVANCED SCIENCE (2019)
EZH2 Phosphorylation Promotes Self-Renewal of Glioma Stem-Like Cells Through NF-κB Methylation
Hailong Liu et al.
FRONTIERS IN ONCOLOGY (2019)
Glioblastoma ablates pericytes antitumor immune function through aberrant up-regulation of chaperone-mediated autophagy
Rut Valdor et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2019)
BRAF Mutations and the Utility of RAF and MEK Inhibitors in Primary Brain Tumors
Karisa C. Schreck et al.
CANCERS (2019)
Longitudinal molecular trajectories of diffuse glioma in adults
Floris P. Barthel et al.
NATURE (2019)
Temozolomide-resistant Glioblastoma Depends on HDAC6 Activity Through Regulation of DNA Mismatch Repair
Go Woon Kim et al.
ANTICANCER RESEARCH (2019)
Immunogenomic analysis reveals LGALS1 contributes to the immune heterogeneity and immunosuppression in glioma
Qun Chen et al.
INTERNATIONAL JOURNAL OF CANCER (2019)
Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
Derin B. Keskin et al.
NATURE (2019)
Hypoxic glioblastoma release exosomal VEGF-A induce the permeability of blood-brain barrier
Chen Zhao et al.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS (2018)
A Glial Signature and Wnt7 Signaling Regulate Glioma-Vascular Interactions and Tumor Microenvironment
Amelie Griveau et al.
CANCER CELL (2018)
Computational Characterization of Suppressive Immune Microenvironments in Glioblastoma
Suvi Luoto et al.
CANCER RESEARCH (2018)
IL-10 induces an immune repressor pathway in sepsis by promoting S100A9 nuclear localization and MDSC development
Isatou Bah et al.
CELLULAR IMMUNOLOGY (2018)
T-Cell Exhaustion Signatures Vary with Tumor Type and Are Severe in Glioblastoma
Karolina Woroniecka et al.
CLINICAL CANCER RESEARCH (2018)
Phase I Study of DNX-2401 (Delta-24-RGD) Oncolytic Adenovirus: Replication and Immunotherapeutic Effects in Recurrent Malignant Glioma
Frederick F. Lang et al.
JOURNAL OF CLINICAL ONCOLOGY (2018)
Microenvironment-Derived Regulation of HIF Signaling Drives Transcriptional Heterogeneity in Glioblastoma Multiforme
Dieter Henrik Heiland et al.
MOLECULAR CANCER RESEARCH (2018)
Oncolytic virotherapy in glioblastoma patients induces a tumor macrophage phenotypic shift leading to an altered glioblastoma microenvironment
Wouter B. L. van den Bossche et al.
NEURO-ONCOLOGY (2018)
Recurrent Glioblastoma Treated with Recombinant Poliovirus
Annick Desjardins et al.
NEW ENGLAND JOURNAL OF MEDICINE (2018)
Deubiquitinating enzyme USP3 controls CHK1 chromatin association and activation
Yu-Che Cheng et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2018)
Ibrutinib inactivates BMX-STAT3 in glioma stem cells to impair malignant growth and radioresistance
Yu Shi et al.
SCIENCE TRANSLATIONAL MEDICINE (2018)
Vascular niche IL-6 induces alternative macrophage activation in glioblastoma through HIF-2 alpha
Qirui Wang et al.
NATURE COMMUNICATIONS (2018)
Blocking distinct interactions between Glioblastoma cells and their tissue microenvironment: A novel multi-targeted therapeutic approach
Melanie Mettang et al.
SCIENTIFIC REPORTS (2018)
Dexamethasone-induced immunosuppression: mechanisms and implications for immunotherapy
Amber J. Giles et al.
JOURNAL FOR IMMUNOTHERAPY OF CANCER (2018)
MAPK8 mediates resistance to temozolomide and apoptosis of glioblastoma cells through MAPK signaling pathway
Peng Xu et al.
BIOMEDICINE & PHARMACOTHERAPY (2018)
Sequestration of T cells in bone marrow in the setting of glioblastoma and other intracranial tumors
Pakawat Chongsathidkiet et al.
NATURE MEDICINE (2018)
Interleukin-10 produced by myeloid-derived suppressor cells is critical for the induction of Tregs and attenuation of rheumatoid inflammation in mice
Min-Jung Park et al.
SCIENTIFIC REPORTS (2018)
Temporal DNA-PK activation drives genomic instability and therapy resistance in glioma stem cells
Yanling Wang et al.
JCI INSIGHT (2018)
Immunovirotherapy with measles virus strains in combination with anti-PD-1 antibody blockade enhances antitumor activity in glioblastoma treatment
Jayson Hardcastle et al.
NEURO-ONCOLOGY (2017)
TMIC-14. TUMOR EVOLUTION OF GLIOMA INTRINSIC GENE EXPRESSION SUBTYPE ASSOCIATES WITH IMMUNOLOGICAL CHANGES IN THE MICROENVIRONMENT
Qianghu Wang et al.
NEURO-ONCOLOGY (2017)
Genetic driver mutations define the expression signature and microenvironmental composition of high-grade gliomas
C. J. Herting et al.
GLIA (2017)
The anti-tumor activity of the STAT3 inhibitor STX-0119 occurs via promotion of tumor-infiltrating lymphocyte accumulation in temozolomide-resistant glioblastoma cell line
Yasuto Akiyama et al.
IMMUNOLOGY LETTERS (2017)
Ultrasmall AGuIX theranostic nanoparticles for vascular-targeted interstitial photodynamic therapy of glioblastoma
Eloise Thomas et al.
INTERNATIONAL JOURNAL OF NANOMEDICINE (2017)
被撤回的出版物: Targeting NEK2 attenuates glioblastoma growth and radioresistance by destabilizing histone methyltransferase EZH2 (Publication with Expression of Concern. See vol. 130, pg. 5027, 2020) (Retracted article. See vol. 130, pg. 6187, 2020)
Jia Wang et al.
JOURNAL OF CLINICAL INVESTIGATION (2017)
Immune microenvironment of gliomas
Anna Gieryng et al.
LABORATORY INVESTIGATION (2017)
Rindopepimut with temozolomide for patients with newly diagnosed, EGFRvIII-expressing glioblastoma (ACT IV): a randomised, double-blind, international phase 3 trial
Michael Weller et al.
LANCET ONCOLOGY (2017)
Restricted Delivery of Talazoparib Across the Blood-Brain Barrier Limits the Sensitizing Effects of PARP Inhibition on Temozolomide Therapy in Glioblastoma
Sani H. Kizilbash et al.
MOLECULAR CANCER THERAPEUTICS (2017)
Gpr124 is essential for blood-brain barrier integrity in central nervous system disease
Junlei Chang et al.
NATURE MEDICINE (2017)
Mutational burden, immune checkpoint expression, and mismatch repair in glioma: implications for immune checkpoint immunotherapy
Tiffany R. Hodges et al.
NEURO-ONCOLOGY (2017)
RANDOMIZED PHASE 3 STUDY EVALUATING THE EFFICACY AND SAFETY OF NIVOLUMAB VS BEVACIZUMAB IN PATIENTS WITH RECURRENT GLIOBLASTOMA: CHECKMATE 143
D. A. Reardona et al.
NEURO-ONCOLOGY (2017)
Tumour exosomes from cells harbouring PTPRZ1-MET fusion contribute to a malignant phenotype and temozolomide chemoresistance in glioblastoma
A-L Zeng et al.
ONCOGENE (2017)
Tumor-derived fibulin-3 activates pro-invasive NF-κB signaling in glioblastoma cells and their microenvironment
M. S. Nandhu et al.
ONCOGENE (2017)
Cancer immunotherapy with recombinant poliovirus induces IFN-dominant activation of dendritic cells and tumor antigen-specific CTLs
Michael C. Brown et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
A single dose of peripherally infused EGFRvIII-directed CAR T cells mediates antigen loss and induces adaptive resistance in patients with recurrent glioblastoma
Donald M. O'Rourke et al.
SCIENCE TRANSLATIONAL MEDICINE (2017)
Glioblastoma-synthesized G-CSF and GM-CSF contribute to growth and immunosuppression: Potential therapeutic benefit from dapsone, fenofibrate, and ribavirin
Richard E. Kast et al.
TUMOR BIOLOGY (2017)
Glioblastoma progression is assisted by induction of immunosuppressive function of pericytes through interaction with tumor cells
Rut Valdor et al.
Oncotarget (2017)
Single-Cell RNA-Seq Analysis of Infiltrating Neoplastic Cells at the Migrating Front of Human Glioblastoma
Spyros Darmanis et al.
CELL REPORTS (2017)
Caspase-8 contributes to angiogenesis and chemotherapy resistance in glioblastoma
Giulia Fianco et al.
ELIFE (2017)
Specificity protein 1-modulated superoxide dismutase 2 enhances temozolomide resistance in glioblastoma, which is independent of O6-methylguanine-DNA methyltransferase
Kwang-Yu Chang et al.
REDOX BIOLOGY (2017)
Targeting Glioma Stem Cell-Derived Pericytes Disrupts the Blood-Tumor Barrier and Improves Chemotherapeutic Efficacy
Wenchao Zhou et al.
CELL STEM CELL (2017)
Infiltrating T Cells Increase IDO1 Expression in Glioblastoma and Contribute to Decreased Patient Survival
Lijie Zhai et al.
CLINICAL CANCER RESEARCH (2017)
Glioblastoma targeted therapy: updated approaches from recent biological insights
M. Touat et al.
ANNALS OF ONCOLOGY (2017)
Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression
Alvaro G. Alvarado et al.
CELL STEM CELL (2017)
Preclinical Efficacy of the MDM2 Inhibitor RG7112 in MDM2-Amplified and TP53 Wild-type Glioblastomas
Maite Verreault et al.
CLINICAL CANCER RESEARCH (2016)
Tumor microenvironment tenascin-C promotes glioblastoma invasion and negatively regulates tumor proliferation
Shuli Xia et al.
NEURO-ONCOLOGY (2016)
Isocitrate dehydrogenase mutations in gliomas
Matthew S. Waitkus et al.
NEURO-ONCOLOGY (2016)
Loss of PTEN Promotes Resistance to T Cell-Mediated Immunotherapy
Weiyi Peng et al.
CANCER DISCOVERY (2016)
Replication protein A and more: single-stranded DNA-binding proteins in eukaryotic cells
Ting Liu et al.
ACTA BIOCHIMICA ET BIOPHYSICA SINICA (2016)
Molecular Profiling Reveals Biologically Discrete Subsets and Pathways of Progression in Diffuse Glioma
Michele Ceccarelli et al.
CELL (2016)
c-Met-mediated endothelial plasticity drives aberrant vascularization and chemoresistance in glioblastoma
Menggui Huang et al.
JOURNAL OF CLINICAL INVESTIGATION (2016)
Clonal evolution of glioblastoma under therapy
Jiguang Wang et al.
NATURE GENETICS (2016)
Regression of Glioblastoma after Chimeric Antigen Receptor T-Cell Therapy
Christine E. Brown et al.
NEW ENGLAND JOURNAL OF MEDICINE (2016)
Clonal neoantigens elicit T cell immunoreactivity and sensitivity to immune checkpoint blockade
Nicholas McGranahan et al.
SCIENCE (2016)
Anti-PD-1 antitumor immunity is enhanced by local and abrogated by systemic chemotherapy in GBM
Dimitrios Mathios et al.
SCIENCE TRANSLATIONAL MEDICINE (2016)
Multiple Subsets of Brain Tumor Initiating Cells Coexist in Glioblastoma
Robert C. Rennert et al.
STEM CELLS (2016)
Efficacy and Safety of Abemaciclib, an Inhibitor of CDK4 and CDK6, for Patients with Breast Cancer, Non-Small Cell Lung Cancer, and Other Solid Tumors
Amita Patnaik et al.
CANCER DISCOVERY (2016)
Spatiotemporal Evolution of the Primary Glioblastoma Genome
Jinkuk Kim et al.
CANCER CELL (2015)
Development of Resistance to EGFR-Targeted Therapy in Malignant Glioma Can Occur through EGFR-Dependent and -Independent Mechanisms
Stefan Klingler et al.
CANCER RESEARCH (2015)
STAT3 Blockade Inhibits Radiation-Induced Malignant Progression in Glioma
Jasmine Lau et al.
CANCER RESEARCH (2015)
Detection, Characterization, and Inhibition of FGFR-TACC Fusions in IDH Wild-type Glioma
Anna Luisa Di Stefano et al.
CLINICAL CANCER RESEARCH (2015)
Whole-genome and multisector exome sequencing of primary and post-treatment glioblastoma reveals patterns of tumor evolution
Hoon Kim et al.
GENOME RESEARCH (2015)
Maintenance Therapy With Tumor-Treating Fields Plus Temozolomide vs Temozolomide Alone for Glioblastoma A Randomized Clinical Trial
Roger Stupp et al.
JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION (2015)
Decreased affinity for efflux transporters increases brain penetrance and molecular targeting of a PI3K/mTOR inhibitor in a mouse model of glioblastoma
Chani M. Becker et al.
NEURO-ONCOLOGY (2015)
Phase 2 trial of dasatinib in target-selected patients with recurrent glioblastoma (RTOG 0627)
Andrew B. Lassman et al.
NEURO-ONCOLOGY (2015)
Nivolumab in Previously Untreated Melanoma without BRAF Mutation
Caroline Robert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Nivolumab versus Docetaxel in Advanced Squamous-Cell Non-Small-Cell Lung Cancer
Julie Brahmer et al.
NEW ENGLAND JOURNAL OF MEDICINE (2015)
Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity
Mona Meyer et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2015)
Mutational landscape determines sensitivity to PD-1 blockade in non-small cell lung cancer
Naiyer A. Rizvi et al.
SCIENCE (2015)
Mesenchymal Stem Cells Isolated From Human Gliomas Increase Proliferation and Maintain Stemness of Glioma Stem Cells Through the IL-6/gp130/STAT3 Pathway
Anwar Hossain et al.
STEM CELLS (2015)
The Blood-Brain Barrier
Richard Daneman et al.
COLD SPRING HARBOR PERSPECTIVES IN BIOLOGY (2015)
Genetic and Functional Diversity of Propagating Cells in Glioblastoma
Sara G. M. Piccirillo et al.
STEM CELL REPORTS (2015)
EZH2 Protects Glioma Stem Cells from Radiation-Induced Cell Death in a MELK/FOXMI-Dependent Manner
Sung-Hak Kim et al.
STEM CELL REPORTS (2015)
A phase II trial of everolimus, temozolomide, and radiotherapy in patients with newly diagnosed glioblastoma: NCCTG N057K
Daniel J. Ma et al.
NEURO-ONCOLOGY (2015)
Expression of DNA mismatch repair proteins MLH1, MSH2, and MSH6 in recurrent glioblastoma
Andreas M. Stark et al.
NEUROLOGICAL RESEARCH (2015)
Phase I study of sorafenib combined with radiation therapy and temozolomide as first-line treatment of high-grade glioma
A. F. Hottinger et al.
BRITISH JOURNAL OF CANCER (2014)
A Randomized Trial of Bevacizumab for Newly Diagnosed Glioblastoma
Mark R. Gilbert et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Bevacizumab for Newly Diagnosed Glioblastoma Reply
Olivier L. Chinot et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
MRI-localized biopsies reveal subtype-specific differences in molecular and cellular composition at the margins of glioblastoma
Brian J. Gill et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2014)
Single-cell RNA-seq highlights intratumoral heterogeneity in primary glioblastoma
Anoop P. Patel et al.
SCIENCE (2014)
EFEMP1 induces gamma-secretase/Notch-mediated temozolomide resistance in glioblastoma
Lotte Hiddingh et al.
ONCOTARGET (2014)
A randomized, double-blind, placebo-controlled phase 2 trial of dendritic cell (DC) vaccination with ICT-107 in newly diagnosed glioblastoma (GBM) patients
Patrick Y. Wen et al.
JOURNAL OF CLINICAL ONCOLOGY (2014)
Bevacizumab plus Radiotherapy-Temozolomide for Newly Diagnosed Glioblastoma
Olivier L. Chinot et al.
NEW ENGLAND JOURNAL OF MEDICINE (2014)
Soluble GARP has potent antiinflammatory and immunomodulatory impact on human CD4(+) T cells
Susanne A. Hahn et al.
BLOOD (2013)
Glioblastoma Stem Cells Generate Vascular Pericytes to Support Vessel Function and Tumor Growth
Lin Cheng et al.
CELL (2013)
The Somatic Genomic Landscape of Glioblastoma
Cameron W. Brennan et al.
CELL (2013)
Inhibition of NF-κB Signaling Ablates the Invasive Phenotype of Glioblastoma
Mike-Andrew Westhoff et al.
MOLECULAR CANCER RESEARCH (2013)
CSF-1R inhibition alters macrophage polarization and blocks glioma progression
Stephanie M. Pyonteck et al.
NATURE MEDICINE (2013)
NABTT 0502: a phase II and pharmacokinetic study of erlotinib and sorafenib for patients with progressive or recurrent glioblastoma multiforme
David M. Peereboom et al.
NEURO-ONCOLOGY (2013)
Identification of prognostic gene signatures of glioblastoma: a study based on TCGA data analysis
Yong-Wan Kim et al.
NEURO-ONCOLOGY (2013)
Human Glioblastoma Multiforme: p53 Reactivation by a Novel MDM2 Inhibitor
Barbara Costa et al.
PLOS ONE (2013)
Intratumor heterogeneity in human glioblastoma reflects cancer evolutionary dynamics
Andrea Sottoriva et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2013)
Reduction of MLH1 and PMS2 confers temozolomide resistance and is associated with recurrence of glioblastoma
Yoshinari Shinsato et al.
ONCOTARGET (2013)
Fibulin-3 Promotes Glioma Growth and Resistance through a Novel Paracrine Regulation of Notch Signaling
Bin Hu et al.
CANCER RESEARCH (2012)
Rapid Radiographic and Clinical Improvement After Treatment of a MET-Amplified Recurrent Glioblastoma With a Mesenchymal-Epithelial Transition Inhibitor
Andrew S. Chi et al.
JOURNAL OF CLINICAL ONCOLOGY (2012)
Wnt activation is implicated in glioblastoma radioresistance
Yonghyun Kim et al.
LABORATORY INVESTIGATION (2012)
A Role for Homologous Recombination and Abnormal Cell-Cycle Progression in Radioresistance of Glioma-Initiating Cells
Yi Chieh Lim et al.
MOLECULAR CANCER THERAPEUTICS (2012)
IDH mutation impairs histone demethylation and results in a block to cell differentiation
Chao Lu et al.
NATURE (2012)
A restricted cell population propagates glioblastoma growth after chemotherapy
Jian Chen et al.
NATURE (2012)
Soluble factors secreted by glioblastoma cell lines facilitate recruitment, survival, and expansion of regulatory T cells: implications for immunotherapy
Courtney A. Crane et al.
NEURO-ONCOLOGY (2012)
Safety, Activity, and Immune Correlates of Anti-PD-1 Antibody in Cancer
Suzanne L. Topalian et al.
NEW ENGLAND JOURNAL OF MEDICINE (2012)
Cross-talk between myeloid-derived suppressor cells (MDSC), macrophages, and dendritic cells enhances tumor-induced immune suppression
Suzanne Ostrand-Rosenberg et al.
SEMINARS IN CANCER BIOLOGY (2012)
Balancing repair and tolerance of DNA damage caused by alkylating agents
Dragony Fu et al.
NATURE REVIEWS CANCER (2012)
Nonreceptor Tyrosine Kinase BMX Maintains Self-Renewal and Tumorigenic Potential of Glioblastoma Stem Cells by Activating STAT3
Olga A. Guryanova et al.
CANCER CELL (2011)
PHASE II EVALUATION OF GEFITINIB IN PATIENTS WITH NEWLY DIAGNOSED GRADE 4 ASTROCYTOMA: MAYO/NORTH CENTRAL CANCER TREATMENT GROUP STUDY N0074
Joon H. Uhm et al.
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS (2011)
Functional characterization of human Cd33+ And Cd11b+ myeloid-derived suppressor cell subsets induced from peripheral blood mononuclear cells co-cultured with a diverse set of human tumor cell lines
Melissa G. Lechner et al.
JOURNAL OF TRANSLATIONAL MEDICINE (2011)
Targeted therapy for high-grade glioma with the TGF-beta 2 inhibitor trabedersen: results of a randomized and controlled phase IIb study
U. Bogdahn et al.
NEURO-ONCOLOGY (2011)
c-Met signaling induces a reprogramming network and supports the glioblastoma stem-like phenotype
Yunqing Li et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2011)
The Hedgehog Pathway Promotes Blood-Brain Barrier Integrity and CNS Immune Quiescence
Jorge Ivan Alvarez et al.
SCIENCE (2011)
Identification of a CpG Island Methylator Phenotype that Defines a Distinct Subgroup of Glioma
Houtan Noushmehr et al.
CANCER CELL (2010)
Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1
Roel G. W. Verhaak et al.
CANCER CELL (2010)
Pharmacologic Inhibition of Cyclin-Dependent Kinases 4 and 6 Arrests the Growth of Glioblastoma Multiforme Intracranial Xenografts
Karine Michaud et al.
CANCER RESEARCH (2010)
Tumor-Induced Tolerance and Immune Suppression Depend on the C/EBPβ Transcription Factor
Ilaria Marigo et al.
IMMUNITY (2010)
A mechanism for vertebrate Hedgehog signaling: recruitment to cilia and dissociation of SuFu-Gli protein complexes
Hanna Tukachinsky et al.
JOURNAL OF CELL BIOLOGY (2010)
Implications for immunotherapy of tumor-mediated T-cell apoptosis associated with loss of the tumor suppressor PTEN in glioblastoma
James S. Waldron et al.
JOURNAL OF CLINICAL NEUROSCIENCE (2010)
LAG-3 Expression Defines a Subset of CD4+CD25highFoxp3+ Regulatory T Cells That Are Expanded at Tumor Sites
Chiara Camisaschi et al.
JOURNAL OF IMMUNOLOGY (2010)
Mechanism of T Cell Tolerance Induced by Myeloid-Derived Suppressor Cells
Srinivas Nagaraj et al.
JOURNAL OF IMMUNOLOGY (2010)
Phase II trial of pazopanib (GW786034), an oral multi-targeted angiogenesis inhibitor, for adults with recurrent glioblastoma
Sandeep Kunwar et al.
NEURO-ONCOLOGY (2010)
Glioma cancer stem cells induce immunosuppressive macrophages/microglia
Adam Wu et al.
NEURO-ONCOLOGY (2010)
Notch Promotes Radioresistance of Glioma Stem Cells
Jialiang Wang et al.
STEM CELLS (2010)
Cetuximab, bevacizumab, and irinotecan for patients with primary glioblastoma and progression after radiation therapy and temozolomide: a phase II trial
Benedikte Hasselbalch et al.
NEURO-ONCOLOGY (2010)
Regulation and Roles for Claudin-family Tight Junction Proteins
Mary K. Findley et al.
IUBMB LIFE (2009)
Phase II Trial of Single-Agent Bevacizumab Followed by Bevacizumab Plus Irinotecan at Tumor Progression in Recurrent Glioblastoma
Teri N. Kreisl et al.
JOURNAL OF CLINICAL ONCOLOGY (2009)
Induction of MGMT expression is associated with temozolomide resistance in glioblastoma xenografts
Gaspar J. Kitange et al.
NEURO-ONCOLOGY (2009)
IDH1 mutations are present in the majority of common adult gliomas but rare in primary glioblastomas
Koichi Ichimura et al.
NEURO-ONCOLOGY (2009)
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
L. Chin et al.
NATURE (2008)
A novel small molecule inhibitor of signal transducers and activators of transcription 3 reverses immune tolerance in malignant glioma patients
S. Farzana Hussain et al.
CANCER RESEARCH (2007)
Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment
Ilona Kryczek et al.
JOURNAL OF IMMUNOLOGY (2007)
Loss of the mismatch repair protein MSH6 in human glioblastomas is associated with tumor progression during temozolomide treatment
Daniel P. Cahill et al.
CLINICAL CANCER RESEARCH (2007)
A perivascular niche for brain tumor stem cells
Christopher Calabrese et al.
CANCER CELL (2007)
Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O-6-methylguanine
W. P. Roos et al.
ONCOGENE (2007)
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
Shideng Bao et al.
NATURE (2006)
The role of human glioma-infiltrating microglia/macrophages in mediating antitumor immune responses
S. Farzana Hussain et al.
NEURO-ONCOLOGY (2006)
An increase in CD4+CD25+FOXP3+ regulatory T cells in tumor-infiltrating lymphocytes of human glioblastoma multiforme
Abdejabar El Andaloussi et al.
NEURO-ONCOLOGY (2006)
Increased regulatory T-cell fraction amidst a diminished CD4 compartment explains cellular immune defects in patients with malignant glioma.
PE Fecci et al.
CANCER RESEARCH (2006)
Inhibiting Stat3 signaling in the hematopoietic system elicits multicomponent antitumor immunity
M Kortylewski et al.
NATURE MEDICINE (2005)
Targeting the c-Met pathway potentiates glioblastoma responses to γ-radiation
BC Lal et al.
CLINICAL CANCER RESEARCH (2005)
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
J Bartkova et al.
NATURE (2005)
MGMT gene silencing and benefit from temozolomide in glioblastoma
ME Hegi et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Radiotherapy plus concomitant and adjuvant temozolomide for glioblastoma
R Stupp et al.
NEW ENGLAND JOURNAL OF MEDICINE (2005)
Identification of human brain tumour initiating cells
SK Singh et al.
NATURE (2004)
The blood-brain barrier: an overview - Structure, regulation, and clinical implications
P Ballabh et al.
NEUROBIOLOGY OF DISEASE (2004)
PTEN methylation and expression in glioblastomas
N Baeza et al.
ACTA NEUROPATHOLOGICA (2003)
Ex vivo isolation and characterization of CD4+CD25+ T cells with regulatory properties from human blood
D Dieckmann et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
VEGF increases BMEC monolayer permeability by affecting occludin expression and tight junction assembly
W Wang et al.
AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY (2001)
Increased production of immature myeloid cells in cancer patients: A mechanism of immunosuppression in cancer
B Almand et al.
JOURNAL OF IMMUNOLOGY (2001)
Characterization of PDZ-binding kinase, a mitotic kinase
S Gaudet et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2000)
Radiation-induced centrosome overduplication and multiple mitotic spindles in human tumor cells
N Sato et al.
EXPERIMENTAL CELL RESEARCH (2000)
Share Paper
