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Bcl6 Mediates the Development of T Follicular Helper Cells
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Inflammatory Bowel Disease and Celiac Disease: Overlaps in the Pathology and Genetics, and their Potential Drug Targets
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Endocrine Metabolic & Immune Disorders-Drug Targets (2009)
Regulatory T cells and immune tolerance
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CELL (2008)
Intratumoural FOXP3-positive regulatory T cells are associated with adverse prognosis in radically resected gastric cancer
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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages
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Transforming growth factor-β 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
Marc Veldhoen et al.
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IL-4 inhibits TGF-β-induced Foxp3+ T cells and, together with TGF-β, generates IL-9+ IL-10+ Foxp3- effector T cells
Valerie Dardalhon et al.
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How regulatory T cells work
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TGF-β and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain TH-17 cell-mediated pathology
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Transient regulatory T-cells: A state attained by all activated human T-cells
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STAT3 regulates cytokine-mediated generation of inflammatory helper T cells
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No alterations in the frequency of FOXP3+ regulatory T-cells in type 1 diabetes
Todd Brusko et al.
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Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
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Quantification of regulatory T cells enables the identification of high-risk breast cancer patients and those at risk of late relapse
Gaynor J. Bates et al.
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CD4+CD25high T cells are enriched in the tumor and peripheral blood of prostate cancer patients
Ashley M. Miller et al.
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T-bet regulates Th1 responses through essential effects on GATA-3 function rather than on IFNG gene acetylation and transcription
T Usui et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2006)
TGFβ in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
M Veldhoen et al.
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Global natural regulatory T cell depletion in active systemic lupus erythematosus
M Miyara et al.
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Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
LE Harrington et al.
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Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule
YL Li et al.
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Decreased FOXP3 levels in multiple sclerosis patients
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Analysis of FOXP3 protein expression in human CD4+CD25+ regulatory T cells at the single-cell level
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EUROPEAN JOURNAL OF IMMUNOLOGY (2005)
Unconventional topology of self peptide-major histocompatibility complex binding by a human autoimmune T cell receptor
M Hahn et al.
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CD4+CD25high regulatory T cells in human autoimmune diabetes
AL Putnam et al.
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Defective suppressor function in CD4(+)CD25(+) T-cells from patients with type 1 diabetes
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Interleukin 2 plays a central role in Th2 differentiation
J Cote-Sierra et al.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA (2004)
Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-β induction of transcription factor Foxp3
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HLA types in celiac disease patients not carrying the DQA1*05-DQB1*02 (DQ2) heterodimer:: Results from the European genetics cluster on celiac disease
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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells
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GATA-3 suppresses Th1 development by downregulation of Stat4 and not through effects on IL-12Rβ2 chain or T-bet
T Usui et al.
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Control of regulatory T cell development by the transcription factor Foxp3
S Hori et al.
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Characterization of CD4+ CTLs ex vivo
V Appay et al.
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Distinct effects of T-bet in TH1 lineage commitment and IFN-γ production in CD4 and CD8 T cells
SJ Szabo et al.
SCIENCE (2002)
IPEX is a unique X-linked syndrome characterized by immune dysfunction, polyendocrinopathy, enteropathy, and a variety of autoimmune phenomena
CL Bennett et al.
CURRENT OPINION IN PEDIATRICS (2001)
CD4+CD25high regulatory cells in human peripheral blood
C Baecher-Allan et al.
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Subspecialization of CXCR5+ T cells:: B helper activity is focused in a germinal center-localized subset of CXCR5+ T cells
CH Kim et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Role of T-bet in commitment of TH1 cells before IL-12-dependent selection
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Ex vivo isolation and characterization of CD4+CD25+ T cells with regulatory properties from human blood
D Dieckmann et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2001)
Identification and functional characterization of human CD4+CD25+ T cells with regulatory properties isolated from peripheral blood
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JOURNAL OF EXPERIMENTAL MEDICINE (2001)
The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3
CL Bennett et al.
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A disease-associated cellular immune response in type 1 diabetics to an immunodominant epitope of insulin
DG Alleva et al.
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Follicular B helper T cells express CXC chemokine receptor 5, localize to B cell follicles, and support immunoglobulin production
D Breitfeld et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
CXC chemokine receptor 5 expression defines follicular homing T cells with B cell helper function
P Schaerli et al.
JOURNAL OF EXPERIMENTAL MEDICINE (2000)
Structure of a covalently stabilized complex of a human αβ T-cell receptor, influenza HA peptide and MHC class II molecule, HLA-DR1
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A novel transcription factor, T-bet, directs Th1 lineage commitment
SJ Szabo et al.
CELL (2000)
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